Description
The main active ingredient of the medicine is highly active recombinant, that is, produced using genetic engineering, interferon a-2. The medication is absolutely safe with respect to virus contamination, which is extremely important, since hepatitis B, C, D, as well as such dangerous pathologies as HIV, CMV and other blood-borne infections are widespread in the modern world.
The medicine is a clear or light yellow liquid, the shelf life of which is two years. An opened plastic bottle should be stored in the refrigerator at a temperature of up to 8 degrees for no more than one month. Instructions for Grippferon are presented below.
Details about the safety of Grippferon: contraindications and side effects of the drug
Grippferon can cause side effects. Among them:
- Dizziness;
- Pain in bones and joints;
- Pain in the eyes;
- Nausea and vomiting;
- Diarrhea;
- Tachycardia;
- Arrhythmia;
- Itching on the skin.
Dizziness and headaches are one of the side effects of Grippferon
Allergic reactions in response to taking Grippferon occur extremely rarely. Still, its active substance does not penetrate into the blood or tissues and cannot affect the body either badly or well.
Several cases of myocardial infarction have been reported, presumably due to the use of Grippferon, so this drug is not recommended for people with diseases of the cardiovascular system.
Grippferon is also contraindicated for:
- Liver cirrhosis;
- Depression;
- Psychosis;
- Alcohol or drug addiction;
- Renal dysfunction.
Lower back pain may be an indicator of kidney problems. In this case, Grippferon cannot be taken.
The most strict adherence to such safety measures is when using Grippferon in the form of an injection solution. Nasal drops are less dangerous and can be used more safely, but if there is the slightest sign of side effects, you should stop using them and consult a doctor immediately.
And you certainly shouldn’t use Grippferon for any runny nose, just to do something. Remember that this is a narrowly targeted remedy, and if the runny nose is not viral, there will be no point in using it.
pharmachologic effect
The mechanism of action of the main substance contained in this drug is based on eliminating the proliferation of any types of viruses that enter the body by any means, including as a result of respiratory activity.
Already on the second day of using this medication, patients experience a significant reduction in the number of viruses excreted during breathing, and, therefore, the risk of infection of people who have been in contact with it is reduced.
Unlike other drugs in this group, it prevents the spread of viruses in the mucous membrane of the nasopharynx, that is, where they primarily enter during ARVI.
This medical product has no direct analogues and is superior to other medications in terms of versatility of action on acute respiratory infections:
- Blocks the reproduction mechanisms of all known types of respiratory viruses that infect humans.
- Has high therapeutic effectiveness.
- Effective as a medicine for emergency prevention.
- Not addictive.
Viruses known to medical science at the present stage are not capable of acquiring resistance to the action of the main substance of the drug “Grippferon”, which is non-toxic and safe. It has been established that the drug reduces the incidence of complications in acute respiratory infections by 50-60% and the number of medications taken by patients by approximately 60-70%.
It has absolutely no contraindications and is compatible with any other medications, including a variety of antiviral drugs. "Grippferon" can be used in conjunction with vaccine prophylaxis. This medical product significantly reduces the number of viruses that are released from the respiratory tract of patients with ARVI (analogous to a bandage), and significantly reduces infectiousness. It also has very pronounced anti-epidemic properties.
Doctors' recommendations for taking Grippferon
The main active ingredient in the drug for ODS is interferon-alpha. It is he who triggers biochemical processes in the body, as a result of which an enzyme is produced that breaks down the virus cells and blocks its reproduction. Another function is that a protective barrier is created around the source of infection from healthy cells, preventing the pathogen from spreading throughout the body. Everyone has long understood that acute respiratory viral infections pose a danger both in themselves and in the form of various complications that affect organs such as:
- heart;
- kidneys;
- vessels, etc.
Therefore, how to use the drug Grippferon, whether taking the medicine to prevent a dangerous disease - coronavirus is justified, must be decided by a specialist observing the patient, who has a complete picture based on the collected medical history.
The drops and spray have no serious contraindications and are recommended for both adults and children over one year of age. The only obstacle to the use of the drug can be the individual characteristics of the patient’s body, causing intolerance to interferons.
Release form and composition
The release form of "Grippferon" is indicated in the instructions. The drug is available in the form of a dosed nasal spray and drops of light yellow or colorless color. They are packaged in plastic bottles of 5 or 10 ml.
What is the composition of the drug “Grippferon”? One dose of spray contains interferon alpha-2b - at least 500 IU. The auxiliary components are sodium chloride, purified water, povidone, sodium hydrogen phosphate dodecahydrate, macrogol, disodium edetate dihydrate, potassium dihydrogen phosphate.
1 ml of drops contains human recombinant interferon alpha-2b of at least 10,000 IU, as well as excipients similar to those in the spray.
Grippferon suppositories
The drug in the form of suppositories is prescribed to newborns and children over one year old. Children from birth are given suppositories one at a time twice a day with an interval of 12 hours. Treatment is carried out for no more than five days. Children over one year of age are prescribed three suppositories per day with an interval of 8 hours. The exact dose of medication should be calculated by the attending physician, depending on the height and weight of the child.
Grippferon for children
The drug in the form of drops is prescribed to children over one year of age and up to three years of age, two drops about 4 times a day. Children aged 3-14 years are prescribed the medicine in a dose of two drops about 5 times a day.
Grippferon in the form of a spray for children over one year of age and up to three years of age is prescribed two drops about 4 times a day. Children under one year of age are prescribed one drop about five times a day. Children aged 3-14 years are prescribed two drops about five times a day.
Grippferon for newborns
The medicine is a modern medication that is absolutely safe to use and intended for use by pregnant women and infants. The drug is produced in the form of nasal drops, which is intended to combat viral and cold infections such as influenza, ARVI, which enter the body through the respiratory tract with inhaled air. This product is quite effective in use and begins to act immediately after the first injection, blocking the movement of pathogenic microbes and preventing them from penetrating further into the body.
Grippferon has a positive effect and prevents complications from pneumonia, sinusitis and bronchitis. Taking the drug for two days reduces harmful and contagious infections.
In case of infection, it is necessary to bury nose drops for five days. For newborn children, one drop is instilled into the nose five times a day; for older children, the single dose is increased to two drops and instilled up to 4 times a day.
Grippferon, side effects
During the use of the drug, no severe side effects were observed, except that in rare cases allergic reactions occurred.
Grippferon, contraindications
The use of the drug is contraindicated if the patient has hypersensitivity to one of its components, as well as if the patient has severe allergic reactions or diseases.
Grippferon, interactions with other drugs
The drug is not prescribed with the simultaneous use of intranasal drugs that have a vasoconstrictor effect.
Grippferon, overdose
To date, there have been no reports of drug overdose.
Grippferon analogues
Analogues of the drug Grippferon are drugs similar to it in structure, such as human recombinant interferon alpha 2b and Reaferon Lipint, as well as drugs similar in their pharmacological group, such as Avonex, Betaferon, Genfaxon, Ingaron, Inferon, Laifferon, Loktoferon, Pegasys, Ronbetal, SinnoVex, Extavia.
Grippferon price
The cost of Grippferon depends on the form of inlet, the country of manufacture and the region in which it is sold, so the real price of the medicine must be clarified in regional pharmacies. The approximate cost of the drug starts from 239 rubles.
Viruses against which the drug is active
At the moment, science knows more than two thousand serotypes of the influenza virus and more than two hundred varieties of other viruses that cause ARVI, each of which can also have hundreds of its own subspecies.
During influenza epidemics, only 20% of all infected people suffer from this particular disease. Other people suffer, as a rule, from other respiratory pathological conditions, against which vaccination and numerous medications do not protect. The drug "Grippferon" is able to affect not only the influenza virus, but also other infections that cause respiratory diseases.
In the course of scientific experimental studies, a pronounced antiviral effect of the drug “Grippferon” on the following types of infections was established:
- All existing strains of the influenza virus, even H1N1.
- Adenovirus AdV 6.
- Human coronavirus HCoV/SPb/01/03 (229E) - one of the types of this virus causes atypical pneumonia.
- Respiratory syncytial virus.
- Rubella virus.
- Edmonston measles vaccine strain.
- Mumps vaccine virus strain L-3.
- Bird flu.
- Parainfluenza virus, strain PG2/SPb5/11/03.
- Lethal strains of avian influenza.
Indications
According to the instructions, it is advisable to use Grippferon at the first symptoms of an acute viral disease, the sooner the better. This medication is used in the following cases:
- Prevention and treatment of respiratory infections - influenza, rotavirus, colds.
- To prevent such diseases.
What is the difference between Grippferon for children and for adults?
The medication can be used in the treatment of newborns, its use is possible during pregnancy, and also for people who, due to weakened immunity, are susceptible to frequent colds, after contact with people already suffering from ARVI and influenza, after hypothermia, etc.
Good effectiveness of children's "Grippferon" was established when using this medicine in preschool institutions. Also among people affected by so-called risk factors. These are health workers, teachers, educators, etc. Indications for the use of Grippferon are described in the instructions.
This medicine is also effective for emergency prevention of viral diseases. Unlike vaccines, which create long-term resistance to certain subtypes of the influenza virus, the medication is used directly in cases where there is a real threat of a respiratory infection after close contact with patients, as well as for colds, etc.
A single dose of medication for individual urgent prevention significantly reduces the risk of the occurrence and development of the disease. In our country, the drug is included in the list of drugs in the state reserve in case of bird flu epidemics.
Application and dosage
As the instructions for Grippferon indicate, when the first manifestations of a respiratory disease occur, this drug should be dripped into the nose. The dosages used are as follows:
- 1 drop five times a day for children under one year of age.
- 2 drops three times a day - for children from one to three years old.
- 2 drops four times a day - from three to 14 years of age.
- 3 drops every four hours - for adults.
For preventive purposes, the drug is used according to age-specific dosages 2 times a day immediately after contact with the patient. Prophylactic therapy lasts several days and can be repeated if necessary.
After instillation, the nose should be massaged with light finger movements for several minutes. This is done to ensure that the medicine is evenly distributed on the nasal mucosa.
When using the drug "Grippferon" there is no need to simultaneously use vasoconstrictor therapy, since it relieves swelling of the mucous membrane and makes breathing easier.
Grippferon spray
The drug in the form of a spray is prescribed intranasally. For correct dosing, you must first press the spray mechanism several times and clean the nasal passages. Before using the medicine, you need to carefully and carefully insert the nozzle into the nasal passage and press the nozzle all the way. The duration of use of Grippferon is determined by the doctor depending on the severity of the disease and the patient’s condition. Adults are prescribed three drops of the drug about five times a day. Treatment is carried out for 5 days. For preventive treatment or hypothermia, the medicine is prescribed three drops twice a day for one day. During seasonal epidemics, the medication is prescribed three drops once every 1-2 days. If re-treatment is necessary, the treatment course is repeated according to the same scheme.
Analogs
"Grippferon" has several analogues, which are medications based on interferons. These medications include:
- "Alfaron."
- "Interferon".
- "Viferon".
- "Kipferon".
- "Cycloferon".
The remaining drugs that are currently presented on the pharmacological market are not similar medications in composition, however, they are analogues of Grippferon in the antiviral direction of action. These include:
- "Ingavirin".
- "Tsitovir".
- "Amiksin".
- "Peramivir".
- "Ingavirin".
- "Rebetol."
- "Lavomax".
- "Kagocel".
- "Tamiflu."
- "Ribavirin".
- "Arbidol".
- "Remantadine."
- "Relenza."
special instructions
In accordance with the instructions for Grippferon, treatment when the first signs of the disease are detected leads to their significant weakening. This applies to a runny nose, cough, headache, fever, mucosal hyperemia, etc.
The duration of pathological conditions is reduced by 50%. In uncomplicated cases, this medication, as a rule, does not require additional symptomatic therapy with aspirin, sulfonamides, or vasoconstrictor nasal drops. When the temperature rises, the drug "Grippferon" can be combined with various antipyretic drugs.
The use of this medication several times reduces the risk of developing complications such as acute bronchitis, sinusitis, pneumonia, etc. The use of the drug for preventive purposes, during epidemics in children's and medical groups, reduces the risk of morbidity by almost three times. This is especially true for pregnant women. There are a large number of reviews about Grippferon.
Action declared by the manufacturer
Grippferon is positioned by the manufacturer and retail chains as a drug with immunomodulatory and antiviral effects. In particular, it is reported that its drops stimulate the body’s defenses, inhibit the development of a viral infection and help to quickly cure the disease if it has already developed.
Some sources even indicate that the use of Grippferon can reduce the recovery time from the flu by 2-3 days.
The manufacturer also indicates that Grippferon can be used to prevent influenza and ARVI during an epidemic, or if necessary, to be in a public place with a risk of infection. In this case, the drops reduce the risk of infection and infection in the body.
Kindergarten is the place where a child has the greatest chance of contracting a viral infection. It is not surprising that parents often use Grippferon specifically to protect their child from infection here.
At the same time, Grippferon does not act directly on viruses, does not destroy them and does not directly disrupt their replication process.
It is also useful to read: Which is better: Grippferon or Interferon?