Neuromultivitis: composition, instructions for use of the drug in tablets and injections, analogues

Composition and release form

The drug Neuromultivit is available in the form of film-coated tablets. The composition is represented by active and auxiliary components, substances that make up the tablet shell.

Pharmacodynamics and pharmacokinetics

Instructions for use of Neuromultivit contain information about each component of the composition. More information about the pharmacodynamics and pharmacokinetics of water-soluble vitamins:

1. Thiamine hydrochloride or vitamin B1 during phosphorylation is converted into cocarboxylase, which serves as a coenzyme and takes part in many enzymatic reactions. The substance is involved in protein, carbohydrate and fat metabolism, the process of conducting nervous excitation in synapses, alpha-keto acids. Thiamin hydrochloride is absorbed in the upper intestine, metabolized in the liver, and excreted by the kidneys.
2. Pyridoxine or vitamin B6 is needed by the body for the normal functioning of all parts of the nervous system. Its phosphorylated form is a coenzyme and takes part in the metabolism of amino acids, including the processes of peramination and decarboxylation of glycosphingolipids. The substance is a coenzyme in enzymatic reactions within nerve tissue. It is involved in the synthesis of the neurotransmitters dopamine, adrenaline, norepinephrine, gamma-aminobutyric acid, and histamine. Pyridoxine is metabolized in the liver and excreted by the kidneys.
3. Vitamin B12 or cyanocobaolamine is involved in the process of normal hematopoiesis, maturation of red blood cells, and biochemical reactions to ensure the vital functions of the body. Without it, the transfer of methyl groups and the exchange of amino acids, lipids and carbohydrates are impossible. The vitamin affects the production of nucleic acids, the lipid composition of phospholipids, and cerebrosides. Coenzyme forms methylcobalamin and adenosylcobalamin take part in the replication and growth of cells and affect acidity. Delivery of cyanocobalamin to tissues occurs due to the protein transcobalamin. The substance is metabolized in the liver and excreted in the bile or kidneys.

Indications for use of Neuromultivit

The instructions highlight a list of diseases and pathological conditions of the nervous system for which Neuromultivit is prescribed. Direct indications for use:

• plexitis (cervical, lumbosacral, shoulder);
• sciatica (damage to the sciatic nerve);
• lumbago (lumbar lumbago, sciatica, lumboischialgia);
• diabetic polyneuropathy;
• alcoholic polyneuropathy, polyneuritis, paralysis;
• mononeuropathy;
• prosoplegia;
• radiculopathy (stimulation of the diseased area);
• psychosis;
• metabolic disorders;
• neuralgia and neuritis;
• trigeminal neuralgia;
• degenerative diseases of the spine with radicular syndrome;
• intercostal neuralgia.

special instructions

The pharmacological features of Neuromultivit made it necessary to indicate a number of special instructions in the instructions. When using the drug you need to pay attention to the following points:

• high doses are allowed to be taken for no more than 4 weeks in a row, otherwise there is a risk of neurological symptoms;
• absorption of thiamine (vitamin B1) decreases when drinking black tea;
• under the influence of sulfites, the process of destruction of thiamine is accelerated;
• due to the presence of vitamin B6 in the drug, it is necessary to prescribe Neuromultivit with caution to patients with duodenal and gastric ulcers, with significant liver and kidney dysfunction;
• in patients with pernicious anemia or funicular myelosis, the use of vitamin B12 may lead to a loss of specificity of the clinical picture of the disease;
• if neoplasms are detected, therapy should be discontinued (exceptions include cases of megaloblastic anemia and B12 deficiency);
• The drug should not be used if you are diagnosed with angina pectoris or with acute or severe decompensation of heart failure.

Neuromultivitis during pregnancy features

During pregnancy, every representative of the fair sex wants to feel good and confident. Therefore, the question arises about the feasibility and safety of taking Neuromultivit during pregnancy. The complex contains vitamin substances that significantly exceed the daily requirement for humans. And this effect is especially harmful for pregnant women. After all, this is a special condition in which even vitamin substances can have a negative effect. Therefore, during the first weeks of pregnancy, in the early stages (1st trimester), the use of the drug is strictly prohibited.

As for the later periods of this condition, certain substances may be used. However, only those products that are intended for pregnant women are allowed. What are they needed for? The answer is simple: to normalize the vitamin balance in a woman’s body. As for this particular composition, it is not recommended to drink it even in the 2nd trimester and 3rd trimester of gestation. This is due to the fact that there is no accurate data on how high dosages of vitamins can affect the expectant mother’s body.

Neuromultivitis for children

According to the instructions, the use of Neuromultivit in children under 12 years of age is contraindicated. This limitation is due to the lack of information about the effectiveness and safety of using the drug in this group of patients. Pediatricians use the medicine earlier, but after the child reaches one year. If you start taking it before one year, there is a risk of overdose - the vitamin content in Neuromultivit is 10 times higher than the baby’s daily requirement.

Prescribing vitamins in pediatrics is necessary to activate metabolic processes occurring at the cellular level, restore functions and improve the condition of the nervous system. Vitamin B6 is important for the child’s psyche, it is an irreplaceable source of energy, participates in the metabolism of amino acids, the transmission of nerve impulses, and the synthesis of neurotransmitters. Vitamin B12 improves oxygen saturation of tissues and organs.

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Neuromultivitis is indicated for inadequate or incorrect diet, neuralgia, increased physical and neuropsychic stress. Children can be given three tablets per day - one three times a day after meals, washed down with a small amount of water. For babies under one year of age, the drug is prescribed with caution, a quarter of a tablet twice a day. It is allowed to crush the dose and mix it with formula or breast milk. You should not take the drug for more than 4 weeks in a row and before bedtime, because insomnia may occur.

Overdose symptoms

With prolonged use of this medication or accidental use of a high dosage, patients may experience overdose symptoms, which are expressed in the form of the following clinical symptoms:

• ataxia;
• neuropathy;
• heart rhythm disturbances;
• seborrheic dermatitis;
• convulsive syndrome;
• changes in data on the electrocardiogram;
• hypochromic anemia;
• eczematous rashes.

If these negative effects occur, treatment with the medication should be discontinued. If necessary, the patient should be given symptomatic treatment.

Instructions for use for Neuromultivit tablets and ampoules confirm this.

Drug interactions

The interaction of Neuromultivit with other medications is described in the instructions. Examples of combinations:

1. The drug reduces the antiparkinsonian effect of Levodopa when used simultaneously.
2. During treatment, you should not take other complex supplements based on B vitamins to avoid the development of hypervitaminosis.
3. 5-fluorouracil minimizes the activity of thiamine because it competitively inhibits its phosphorylation to cocarboxylase.
4. Antacids slow down the absorption of vitamin B1.
5. Long-term use of Neuromultivit with loop diuretics, Furosemide, and other agents to inhibit tubular reabsorption increases the elimination of thiamine and reduces its level.
6. When combining the drug with pyridoxine antagonists, antituberculosis drugs Isoniazid and Cycloserine, penicillamine, the vasodilator Hydralazine, and oral contraceptives, the need for vitamin B6 increases.

Side effects and interactions with other medications

The medicine is well tolerated and rarely has side effects. Side effects of the drug include nausea, vomiting, dizziness, increased heart rate, general weakness, allergic reactions of the skin (redness, rash, itching). If these symptoms occur, you should stop taking Neuromultivit and consult your doctor.

Before starting treatment, you should carefully read the instructions for interactions of the drug with other medications. The combination of Neuromultivit with medications containing alcohol leads to a deterioration in the absorption of vitamin B1. There can be no talk of any compatibility between Neuromultivit and alcohol.

It is forbidden to combine the drug with other supplements containing B vitamins. Taking it reduces the effectiveness of levodopa in the treatment of Parkinson's disease.

Analogs

You can replace the product with drugs based on B vitamins. These include:

• Angiovit - tablets with the same component composition with the addition of glucose;
• Multi-tabs B-complex – multivitamin tablets with B vitamins and others;
• Beviplex – lyophilized powder for injection solution based on a vitamin complex;
• Pentavit - tablets with the same composition, enhanced with nicotinamide and folic acid;
• Purified dry brewer's yeast - powder or capsules with B vitamins, amino acids;
• Medivitan is a solution of B vitamins to replenish their deficiency.

Milgamma or Neuromultivit – which is better?

Neuromultivit solution and tablets are often compared with the drug Milgamma. It contains the same active ingredients, but is additionally enhanced with lidocaine so that the injection is not so painful. Milgamma tablets do not contain lidocaine, so they can be considered a structural analogue of Neuromultivit. The doctor decides which one is better, but we must remember that Milgamma cannot be used in the treatment of children.

Instructions for use

Apply like this:

1. 1 tablet 1 or 3 times a day, as prescribed by the treating doctor.
2. Used for greatest effectiveness immediately after eating. Do not chew or crush, otherwise the properties of the drug will change.
3. Take it with water or tea; you can’t take it with anything else.
4. The duration of the appointment is prescribed by the doctor, but usually no more than a month.

Neuromultivit price

The drug Neuromultivit is sold in pharmacy chains or online departments. Its cost depends on the form of release and pricing policy. In Moscow prices will be: