Absolutely forbidden
Fluorocort ointment should not be prescribed to patients if they have been diagnosed with a high level of hypersensitivity to any component of the composition. It is contraindicated to use the medication as the main and only treatment option for the following diagnoses:
- Syphilis in the presence of skin rashes;
- Plaque type psoriasis;
- Tuberculosis;
- Scabies in the presence of parasitic infestations;
- Penetration of fungus or bacteria;
- Itching in the genital area;
- Varicose veins in the lower extremities;
- Diaper rash caused by using wet diapers.
These and other diseases can be treated with this drug only in combination with specific therapy. In addition, the doctor does not prescribe Fluorocort to lubricate the skin of the breast before feeding the baby if it has dry peeling. Contraindicated for use in children under 1 year of age. The ointment does not treat skin reactions after vaccination, and is also not used to eliminate rosacea on the face or perioral dermatitis. It is strictly forbidden to apply the mixture to the skin of the eyelids and lubricate the area around the eyes.
Contraindicated
Increased sensitivity to triamcinolone acetonide or any other drug.
The drug cannot be applied to the eyes or skin of the eyes.
Staying in monotherapy without specific treatment for fungal and bacterial skin infections; tuberculosis; viral skin infections, especially with simple herpes and chickenpox; for parasitic infections (scab); show syphilis in the skin; skin reactions after vaccination; perianal and genital itching; viraza gomilka; varicose veins; expansion of plaque psoriasis; skin lesions (acne vulgaris, acne vulgaris, oral dermatitis); skin leaks caused by wet pellets; bathing the dry peeling of the skin and applying ointment to the chest directly before bathing the chest; children age until 1st birthday.
Details about the components of the product
The ointment is made on the basis of cetyl alcohol and stearic acid, which are only auxiliary ingredients. The active substance is triamcinolone. To prepare 1 g of the product, it must be taken in an amount of 1 mg. To maintain the shape and consistency, liquid paraffin and glycerin are added to the preparation; other fillers are polysorbate 60 and E218. The result is a homogeneous ointment that has virtually no odor. It is usually either white or transparent.
Topical corticosteroids provide pain relief due to the presence of fluoride in the composition. The substance reduces the intensity of allergic manifestations, relieves swelling, redness, itching and eliminates pain. The drug Ftorokort is characterized as a quick remedy, because it is able to penetrate deeply into the layers of the skin, and then the active substances easily enter the blood.
The active ingredients of the drug increase the body's resistance to stress, while utilizing glucose and enhancing gluconeogenesis. After applying the ointment, the blood vessels narrow, tissue swelling is relieved, and the risk of permeability is reduced. At the same time, the medicine has a positive effect on internal organs: vascular resistance in the lungs decreases, and the bronchi expand.
The elimination process takes about 5 hours, but the ingredients are metabolized, so some goes to the kidneys and liver. The half-life of the substances occurs in 18-36 hours.
Contraindications
The official instructions for use indicate contraindications for the drug Fluorocort:
- Lupus.
- Malignant tumors.
- Perioral dermatitis.
- Cutaneous syphilis.
- Leg ulcers.
- Varicose veins
- Infectious diseases.
It is forbidden to apply the drug to the area around the eyes. Cannot be used by children under one year of age. The duration of therapy in children over one year of age is a maximum of five days.
The drug should not be used in the first trimester of pregnancy. In the second and third cases, treatment is allowed, but only after consultation with the attending physician and in case of urgent need.
Interesting to know
The active component of the drug passes into breast milk, so it should not be used by nursing mothers.
According to the instructions, Fluorocort may cause side effects. Although the medicine penetrates very quickly into the subcutaneous layer, this hormonal drug enters the blood in very small quantities. The percentage of the active component entering the blood increases only when there is little oxygen access to the skin, that is, under an occlusive dressing.
Of the side effects, only symptoms of allergy to the composition of the ointment were noted. It manifests itself in the form of peeling skin, redness, and itching. There are also cases of secondary infections, skin pigmentation and folliculitis.
In some cases, the ointment is applied under elastic bandages. Although this method increases the effectiveness of the drug, it also increases the risk of side effects. If after a few days of using the ointment the therapeutic effect of the ointment is not observed, you should consult a dermatologist. Most likely, the doctor will prescribe an analogue of the action of this drug and change the treatment regimen.
Side effects
Side effects appear when the instructions for use are violated - an overdose of the drug or when the duration of treatment exceeds 1 month. Side effects appear:
- perioral dermatitis;
- sweating;
- poor wound healing;
- hypopigmentation;
- allergic dermatitis;
- skin maceration;
- skin irritation, dryness, itching;
- folliculitis;
- excessive hair growth;
- skin atrophy.
With prolonged use or application to large areas of the skin, side effects are likely that are characteristic of all GCS, for example: insomnia, anxiety, adrenal insufficiency, secondary immunodeficiency, steroid diabetes mellitus, Itsenko-Cushing syndrome, arterial hypertension, myocardial dystrophy, cardiac arrhythmias , swelling, muscle weakness, muscle atrophy, osteoporosis, steroid gastric ulcers, intestinal atony, tendency to thrombus formation, skin atrophy, allergic reactions.
Pharmacological properties
Triamcionolone is a hormone that, like other hormones, significantly accelerates metabolic processes occurring inside the body. Thus, this leads to the stabilization of mast cell membranes, the number of inflammatory processes decreases, and the condition of the epithelial layers significantly improves.
The advantage of the hormone is its rapid penetration deep into the epidermis, due to which swelling resolves, fluid leaves, and the number of neutrophils decreases. An action that is expressed as:
- accelerating the process of lipocortin production. They eliminate allergy symptoms, reduce inflammation;
- increasing the rate of lipid metabolism;
- reducing the amount of histamine;
- regulation of the permeability of the walls of blood vessels, due to which timely outflow of fluid occurs.
A person gets rid of redness, itching, and discomfort. Patients begin to feel better.
Analogs
Fluorocrt ointment is used based on the tolerability of the components and indications for treatment. However, if necessary, the drug can be replaced with other medications.
The drug has several substitutes for the active component and several medications with similar pharmacological effects:
Triacort. It is produced in the form of liniment for outdoor use. The main component is triamcinolone. Belongs to the class of anti-inflammatory, antiallergic pharmaceuticals. Eliminates signs of itching and is prescribed for complex treatment of skin pathologies. Effective in the treatment of eczema, psoriasis, and various forms of dermatitis. Contraindicated in the presence of infectious and bacterial lesions of the skin. Liniment is applied to the affected area 1-3 times a day. The duration of therapy is 5-10 days. It is prohibited to use the drug for more than 25 days. Cost – 120-140 rubles. for the remedy.
Berlicourt. Available in tablet form. The main active ingredient is triamcinolone. Belongs to the group of glucocorticosteroids. It has a pronounced antipruritic and anti-inflammatory effect. Prescribed in the treatment of skin diseases and internal infectious lesions. There are contraindications: pregnancy, stomach ulcers, mental disorders. The daily norm is calculated based on the weight and age of the patient. May be used as maintenance therapy. The duration of the course depends on the established form of the disease.
Akriderm. It is produced in the form of ointment and cream. The active ingredient is betamethasone. Belongs to the class of glucocorticosteroids. Shows a pronounced anti-inflammatory and antipruritic effect. Used for various types of dermatitis, psoriasis. Active against some gram-positive and gram-negative microorganisms. Has an antifungal effect. Prohibited for use in case of development of infectious skin lesions, including skin tuberculosis, herpetic lesions, chicken pox. Not prescribed for children under 1 year of age. Standard treatment regimen: lubricate the affected area twice a day - in the morning and at night. The course of treatment depends on the disease. The cost of the drug ranges from 80 to 173 rubles. per package.
Lokoid ointment. Belongs to the group of anti-inflammatory steroid drugs. The main substance is hydrocortisone. It has anti-inflammatory, anti-edematous and antipruritic properties. Used for various skin diseases. Effective in complex therapy of various forms of dermatitis and psoriasis. Contraindicated for infectious and fungal lesions of the skin
Use with caution during pregnancy. Apply the composition 1-3 times a day
The duration of treatment is determined by the doctor, based on the severity and nature of the disease. Cost – 266-283 rubles.
Triderm. Available in the form of liniment - ointment and cream. A combined anti-inflammatory drug belonging to the group of hormonal external agents. Used for various forms of dermatitis, including allergic forms. Effective in the complex treatment of psoriasis and dermatomycosis. The medicine is prohibited for use in certain infectious diseases: skin tuberculosis, chicken pox, herpes simplex virus. Age restrictions – up to 2 years. Can be used with caution during pregnancy. The composition is applied to the affected area 2 times a day. If there is no therapeutic effect after a month, the drug must be discontinued. Cost – from 600 to 650 rubles.
Belosalik. It is produced in the form of liniment or topical lotion. Belongs to the class of combined hormonal pharmaceuticals. Shows keratolytic, anti-inflammatory and antiallergic properties. Contraindications: children under 2 years of age. Can be used during pregnancy only under medical supervision. Treatment regimen: apply the composition 2 times a day. Treatment is carried out over 21 days; in childhood, the course of therapy should not exceed 5 days. The cost of the medicine in Moscow pharmacies varies between 190-430 rubles.
Analogs should only be selected by the treating specialist. Self-prescription of substitutes may lead to undesirable reactions.
Fluorocort application
The drug is used to treat skin diseases of various etiologies, except infectious skin diseases. In addition, the medicine treats acute and chronic eczema, itching in the genital and anal areas, contact dermatitis and neurodermatitis, including dermatitis of the external auditory canal and Dühring's hepertiform dermatitis. This remedy effectively treats lichen planus, discoid lupus erythematosus, verrucous verrucous, pemphigus vulgaris, psoriasis and balanitis, pityriasis rosea and granuloma annulare. The drug also showed good results in the treatment of patients with urticaria, photosensitivity, patients with symptoms such as itching and burning, skin damage as a result of insect bites and sunburn. The drug can be used to treat Leiner's disease.
Fluorocort ointment
The drug in the form of an ointment is applied in a thin layer to the affected areas of the skin, without rubbing. It should be applied about three times a day. Adults are prescribed to apply the drug under an occlusive dressing. Under an occlusive dressing, it is necessary to apply the medicine no more than 10 g per day, without it the maximum daily dose should be 15 g. The duration of treatment for adults is determined by the attending physician, depending on the severity of the disease and the patient’s condition; children and the elderly are prescribed a course of treatment of no more than five days and without use of an occlusive dressing.
Fluorocort, side effects
When using the drug, side effects occur quite rarely. Sometimes erythema and hypertrichosis, pyoderma are observed; with prolonged use of the ointment, skin atrophy may occur; when using the ointment under an occlusive dressing, suppression of the hypothalamic-pituitary-adrenal system may occur, a decrease in the synthesis of endogenous corticosteroids, carbohydrate metabolism may be disrupted, and blood pressure may change.
Fluorocort: pregnancy and lactation
The drug in the form of an ointment is prescribed to pregnant women if it will benefit the mother and will not harm the fetus. In such cases, use the drug in a minimal amount and stop using it immediately after the clinical picture improves. Do not use the ointment on large areas of skin, on the face and in skin folds, and do not use occlusive dressings. During breastfeeding, it is better to stop using the drug.
Fluorocort, contraindications
The ointment is not prescribed if the patient has hypersensitivity to one of the components of the drug, with infectious skin diseases and tuberculosis, with perioral dermatitis, malignant formations, precancerous skin diseases, with syphilis diseases with severe skin manifestations.
Fluorocort price
The cost of the drug depends on the country of manufacture and the region in which it is sold, so the real cost must be clarified in regional pharmacies. The approximate price of the ointment ranges from 110.12 rubles. up to 175 rub.
Description of the drug
Fluorocort is a thick white ointment with a homogeneous consistency without any specific odor. Its ingredients penetrate into all epidermal layers, beginning to have a therapeutic effect after a few minutes. The drug is used in the treatment of skin diseases of non-infectious origin.
What is Fluorocort ointment used for:
- elimination of allergic rashes formed under the influence of external or internal negative factors;
- reducing the severity of pain;
- resorption of edema of inflammatory origin;
- restoration of optimal permeability of blood vessels;
- relief from burning sensation and itchy skin.
The drug is used in dermatology to treat both acute and chronic pathologies. It is included in therapeutic regimens to eliminate all symptoms of allergic diseases at once. This allows you to avoid the pharmacological load on the body that occurs when using a combination of external drugs.
Pharmacological group and action
Fluorocort is a representative of the clinical and pharmacological group of glucocorticosteroids for external use. The multifaceted therapeutic effect allows it to be classified as an anti-inflammatory, decongestant, and analgesic agent.
Patients often ask dermatologists whether Fluorocort is a hormonal drug or not. The active ingredient of the ointment is a glucocorticosteroid, a synthetic analogue of hormones produced by the adrenal glands. It is due to the steroid component that the drug has a pronounced therapeutic effect:
- stimulates the synthesis of lipocortins - proteins involved in the construction of DNA. As a result, the biosynthesis of arachidonic acid, which serves as a building material for prostaglandins, is inhibited. It is these mediators that are responsible for the development of acute and chronic inflammatory processes;
- due to a decrease in the activity of cellular phospholipase enzymes, leukotrienes, prostacyclins, and thromboxane cease to be produced. This leads to a decrease in the intensity of pain and fever;
- the permeability of vascular walls is optimized, preventing the accumulation of pathological exudate. Macrophages stop penetrating into inflammatory foci, causing the formation of edema;
- The body stops producing histamine, a mediator of immediate allergic reactions.
The diverse effects of the synthetic hormone help improve blood circulation in tissues affected by inflammation. They replenish reserves of nutrients and biologically active substances, accelerating skin restoration. The use of the drug allows you to avoid the formation of scars, spots, pits after severe damage to the dermis.
Release form and composition
The drug is produced in a Hungarian pharmaceutical factory. It is packaged in 15 g units in hermetically sealed aluminum tubes. Secondary packaging is a cardboard box with instructions for use included. The active ingredient of the ointment is triamcinolone acetonide.
The auxiliary composition of Fluorocort is represented by the following ingredients:
- stearic acid;
- methyl parahydroxybenzoate;
- polysorbate 60;
- glycerol (an aqueous solution of glycerin);
- liquid paraffin;
- cetyl alcohol;
- purified water.
Additional components ensure maximum absorption of the glucocorticosteroid into pathological lesions. They moisturize the skin, preventing the evaporation of much-needed moisture. Paraffin is evenly distributed on the surface of the epidermis, forming a thin, durable film. Molecular oxygen freely penetrates through it, but not pathogenic bacteria and pathogenic fungi.
The optimal temperature for storing the drug is 8-15°C. If it is violated, the ointment separates, its color and smell change. This indicates deterioration of the drug and its unsuitability for therapy. The shelf life of Fluorocort is 24 months, after opening the tube it is limited to several weeks.
Fluorocort ointment – what is it used for, instructions for use, reviews
Fluorocort ointment is a medicinal product used for various skin diseases. According to the instructions, it can be used as an anti-infective agent. How to use, what helps and what the price of the ointment is, we will consider later in the article.
Fluorocort - what is it?
Fluorocort is a drug for external use used in dermatological practice. The ointment is prescribed to patients for the treatment of allergic dermatoses, eczema, psoriasis, and neurodermatitis.
The active ingredient of the product - triamcinolone - has a pronounced anti-inflammatory, antiproliferative, antipruritic effect.
It quickly copes with swelling, skin itching, and painful sensations of varying intensity.
Latin name | Fluorocort |
ATX code | D07AB09 |
Active substance | Triamcinolone |
Manufacturer | JSC “Gedeon Richter”, Hungary |
Price from | 219 rub. |
Compound
1 gram of Fluorocort ointment consists of:
- 1 mg - triamcinolone acetonide - active substance.
Auxiliary ingredients:
- 0.025 g - stearic acid;
- 0.002 g – methyl parahydroxybenzoate;
- 0.035 g - polysorbate 60;
- 0.18 g – 85% glycerol;
- 0.12 g – liquid paraffin;
- 0.06 g – cetyl alcohol;
- 0.577 g - purified water.
Release form and packaging
The drug is produced in a Hungarian pharmaceutical factory. It is packaged in 15 g units in hermetically sealed aluminum tubes. Secondary packaging is a cardboard box with instructions for use included.
pharmachologic effect
GCS for external use. When applied topically, it has anti-inflammatory, antiallergic, anti-edematous and antiproliferative effects.
When exposed to the skin, the marginal accumulation of neutrophils is prevented, which leads to a decrease in exudation, cytokine production, inhibition of macrophage migration, ultimately leading to a decrease in the processes of infiltration and granulation.
Pharmacodynamics and pharmacokinetics
The main component of liniment has a high penetrating ability, and therefore is quickly distributed throughout the tissues of the body. As a result of metabolism, the active substance is metabolized to 6-beta-hydroxytriamcinolone.
The majority of drug components are excreted through the kidneys and intestines. The half-life of the main component from the blood is observed after 5 hours, from body tissues - from 18 to 36 hours.
What is Fluorocort used for? Indications
What does Fluorocort ointment help with? Skin diseases sensitive to GCS:
- acute and chronic eczema;
- neurodermatitis;
- contact dermatitis;
- lichen planus;
- psoriasis;
- exfoliative erythroderma;
- Leiner's disease;
- external otitis, not complicated by infection;
- insect bites.
Contraindications ⛔
Contraindications for use of Fluorocort:
- hypersensitivity to the components of the drug;
- viral, bacterial (including tuberculosis) and fungal skin infections;
- trophic ulcer of the leg;
- rosacea;
- acne vulgaris;
- perioral dermatitis;
- intertrigo;
- cannot be applied to wounds;
- children under 2 years of age.
⛔
Source: https://travmatolog.net/ftorokort-maz/
special instructions
Corticosteroids should not be used around the eyes or on open lesions
The medication should be used with extreme caution under an occlusive dressing or on large surfaces. This therapeutic approach in children requires constant monitoring by the attending physician.
If complications develop due to secondary fungal or bacterial infection, treatment is carried out with the prescription of additional drugs belonging to the group of antifungal or antimicrobial drugs.
Use in children
The ointment should be used with great caution in childhood due to the immaturity (underdevelopment) of the skin.
It is better not to apply fluorocort to children
When using the product systemically, the reabsorption of active components may increase due to the presence of skin folds in the child or the use of diapers that act as an occlusive dressing.
Also, a similar effect may occur due to the presence of a relationship between skin and body weight. This can cause dysfunction of the adrenal cortex.
The duration of therapy in childhood should be no more than 5 days. If necessary, the course can be extended, but only under the strict supervision of the attending physician. In this case, it is prohibited to use liniment under an occlusive dressing.
The use of an occlusive dressing may lead to the development of adverse reactions. Under the influence of liniment, the skin softens and the absorption capacity increases. In this case, pathogenic microflora penetrates, promoting the development of secondary infections. Occasionally, bleeding may occur at the sites where the bandage is applied.
Use in the elderly requires dose adjustment and reduction in treatment duration. With long-term use of the drug in the treatment of lichen planus, a decrease in the effectiveness of therapy is observed.
The medicine does not have a negative effect on the ability to drive motor vehicles or perform work associated with increased concentration.
Indications for use
What does Fluorocort help with? The drug is prescribed in the following cases:
- eczema;
- atopic dermatitis (neurodermatitis);
- psoriasis;
- dermatitis of various etiologies (including allergic);
- photodermatoses;
- hypertrophic and keloid scars;
- lichen planus;
- discoid lupus erythematosus;
- insect bites.
If the diagnosed disease is complicated by the addition of a secondary fungal or bacterial infection, a specific antifungal or antibacterial drug should be added to treatment with Fluorocort ointment.
Instructions for use, dosage of the drug
The dosage and duration of the course are determined by the treating dermatologist, based on the form of the disease and the nature of the inflammatory processes.
Typically, the composition is applied 1-2 times a day - in the morning and at night. The duration of therapy in this case should be from 3 to 7 days. With longer exposure to the drug, children may develop signs of secondary infection and a decrease in therapeutic effect.
When using the product in childhood, it is recommended to dilute liniment with any other baby cream to avoid the development of side effects or addiction. In more severe cases, it is recommended to apply the ointment 2-3 times a day. The duration of treatment with steroid drugs should not exceed 5 days.
Liniment can be used with an occlusive dressing. However, in this case, the daily dosage should be no more than 10 g.
For severe skin lesions with dermatitis, the duration of treatment can be up to 25 days. In this case, therapy is carried out only under the supervision of a doctor.
Maximum use of the ointment should not exceed 1 month. Otherwise, the risks of developing side effects and addiction increase. If you miss the required dose, it is not recommended to use the drug in double dosage. The effectiveness of treatment is not observed.
FLUOROCORT
Drug: FLUOROCORT Active substance: triamcinolone acetonide ATC code: D07AB09 KFG: GCS for external use Reg. number: P No. 011862/01 Registration date: 07/15/05 Owner of reg. cert.: GEDEON RICHTER Ltd. {Hungary}
DOSAGE FORM, COMPOSITION AND PACKAGING
? Ointment for external use 0.1% white or almost white, homogeneous, practically odorless.
1 g | |
triamcinolone acetonide | 1 mg |
Excipients: methyl parahydroxybenzoate, stearic acid, polysorbate 60, cetyl alcohol, liquid paraffin, glycerol 85%, purified water.
15 g - aluminum tubes (1) - cardboard packs.
DESCRIPTION OF THE ACTIVE SUBSTANCE.
The scientific information provided is general and cannot be used to make a decision about the possibility of using a particular drug. PHARMACHOLOGIC EFFECT
GKS. Suppresses the functions of leukocytes and tissue macrophages. Limits the migration of leukocytes to the area of inflammation. It disrupts the ability of macrophages to phagocytose, as well as to form interleukin-1. Helps stabilize lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in the area of inflammation. Reduces capillary permeability due to the release of histamine. Suppresses fibroblast activity and collagen formation.
Inhibits the activity of phospholipase A2, which leads to suppression of the synthesis of prostaglandins and leukotrienes. Suppresses the release of COX (mainly COX-2), which also helps to reduce the production of prostaglandins.
Reduces the number of circulating lymphocytes (T- and B-cells), monocytes, eosinophils and basophils due to their movement from the vascular bed into the lymphoid tissue; suppresses the formation of antibodies.
Suppresses the release of ACTH and β-lipotropin by the pituitary gland, but does not reduce the level of circulating β-endorphin. Inhibits the secretion of TSH and FSH.
When directly applied to blood vessels, it has a vasoconstrictor effect.
It has a pronounced dose-dependent effect on the metabolism of carbohydrates, proteins and fats. Stimulates gluconeogenesis, promotes the uptake of amino acids by the liver and kidneys and increases the activity of gluconeogenesis enzymes. In the liver, it enhances the deposition of glycogen, stimulating the activity of glycogen synthetase and the synthesis of glucose from the products of protein metabolism. An increase in blood glucose levels activates the release of insulin.
Suppresses the uptake of glucose by fat cells, which leads to activation of lipolysis. However, due to increased insulin secretion, lipogenesis is stimulated, which promotes fat accumulation.
It has a catabolic effect in lymphoid and connective tissue, muscles, adipose tissue, skin, bone tissue.
Osteoporosis and Itsenko-Cushing syndrome are the main factors limiting long-term GCS therapy. As a result of the catabolic effect, growth suppression in children is possible.
In high doses, it can increase the excitability of brain tissue and help lower the threshold for convulsive readiness. Stimulates excess production of hydrochloric acid and pepsin in the stomach, which contributes to the development of peptic ulcers.
When used systemically, the therapeutic activity is due to anti-inflammatory, antiallergic, immunosuppressive and antiproliferative effects.
When applied externally and locally, the therapeutic activity of triamcinolone acetonide is due to its anti-inflammatory, antiallergic and antiexudative (due to the vasoconstrictor effect) effect.
In terms of anti-inflammatory activity, triamcinolone acetonide is 6 times more active than hydrocortisone. Triamcinolone acetonide has virtually no mineralocorticoid activity.
PHARMACOKINETICS
When administered systemically, it is metabolized mainly in the liver and partially in the kidneys. The main route of metabolism is 6-β-hydroxylation. T1/2 - 3.5 hours. Excreted by the kidneys.
INDICATIONS
For systemic use: bronchial asthma, chronic bronchitis with broncho-obstructive syndrome, pemphigoid, psoriasis, dermatitis.
Intra-articular administration: chronic inflammatory diseases of the joints, exudative arthritis, gout, edema of the joints, blockade of the shoulder joint, chronic inflammation of the inner layer of the joint capsule.
For external use: eczema, psoriasis, neurodermatitis, various types of dermatitis and other inflammatory and allergic skin diseases of non-microbial etiology (as part of complex therapy).
DOSING REGIME
Individual, depending on the indications and dosage form used.
SIDE EFFECT
From the endocrine system: redistribution of adipose tissue, menstrual irregularities, increased blood glucose levels, suppression of adrenal function, “moon face”, stretch marks, hirsutism, acne.
Metabolism: edema, electrolyte imbalance, negative nitrogen balance, growth retardation in children.
From the digestive system: steroid gastric ulcer, erosive and ulcerative lesions of the gastrointestinal tract, acute pancreatitis.
From the central nervous system: convulsions, sleep disturbances, mental disorders, headaches and dizziness, weakness.
From the musculoskeletal system: myopathy, osteoporosis.
From the cardiovascular system: arterial hypertension.
From the blood coagulation system: thromboembolism.
From the organ of vision: visual disturbances, posterior subcapsular cataracts, increased intraocular pressure or exophthalmos, anaphylactic reactions.
Reactions caused by immunosuppressive effects: exacerbation of infectious diseases.
With intra-articular administration: possible joint pain, irritation at the injection site, depigmentation, sterile abscess, skin atrophy; when administered in doses of more than 40 mg, resorptive side effects are possible.
When used externally: possible itching, skin irritation, late reactions such as eczema, steroid acne, purpura. With prolonged use of the ointment, the development of secondary infectious lesions and atrophic changes in the skin is possible.
CONTRAINDICATIONS
History of acute psychosis, active form of tuberculosis, myasthenia gravis, neoplasms with metastases, diverticulitis, gastric and duodenal ulcers, arterial hypertension, Itsenko-Cushing syndrome, renal failure, history of thrombosis and embolism, osteoporosis, diabetes mellitus, hidden foci of infection, amyloidosis, syphilis, fungal diseases, viral infections (including those caused by Herpes simplex and Varicella zoster), amoebic infections, poliomyelitis (except for the bulbar-encephalitis form), gonococcal or tuberculous arthritis, vaccination period, lymphadenitis after BCG vaccination, glaucoma , infected skin lesions.
PREGNANCY AND LACTATION
If use is necessary during pregnancy (especially in the first trimester) and lactation, the expected benefit to the mother and the risk of side effects in the fetus or child should be assessed.
SPECIAL INSTRUCTIONS
Not intended for intravenous administration.
Use with caution and under strict medical supervision for edema syndrome, obesity, mental illness and gastrointestinal diseases. During treatment, it is recommended to take vitamin D and eat foods rich in calcium.
For external use, to prevent local infectious complications, it is recommended to use it in combination with antimicrobial agents.
Parenteral use in children under 6 years of age is not recommended; at the age of 6-12 years - according to strict indications.
Long-term external use should be avoided in children regardless of age.
DRUG INTERACTIONS
When used simultaneously with anabolic steroids and androgens, the risk of developing peripheral edema and acne increases.
When used simultaneously with antithyroid drugs and thyroid hormones, changes in thyroid function may occur.
When used simultaneously with histamine H1 receptor blockers, the effect of triamcinolone is reduced; with hormonal contraceptives - the effect of triamcinolone is potentiated.
Hypocalcemia associated with the use of triamcinolone may lead to an increase in the duration of neuromuscular blockade caused by the action of depolarizing muscle relaxants when used concomitantly.
When used simultaneously with immunosuppressants, the risk of developing bacterial and viral infections increases.
When used simultaneously with potassium-sparing diuretics, hypokalemia is possible.
With simultaneous use, it is possible to reduce the effectiveness of indirect anticoagulants, heparin, streptokinase, urokinase, and increase the risk of erosive and ulcerative lesions and bleeding from the gastrointestinal tract.
When used simultaneously with NSAIDs (including acetylsalicylic acid), the risk of erosive and ulcerative lesions and bleeding from the gastrointestinal tract increases.
With simultaneous use, the effect of oral hypoglycemic agents and insulin is weakened; with laxatives - hypokalemia is possible; with cardiac glycosides - the risk of developing heart rhythm disturbances and other toxic effects of glycosides increases.
When used simultaneously with tricyclic antidepressants, an increase in mental disorders associated with triamcinolone may be possible.
Instructions for use
The use of the drug has its own characteristics that determine its clinical effectiveness. Therefore, before using it, you should consult your doctor and also read the attached instructions. Treatment with cream will not give the desired result if the cause of the rash is pathogenic microorganisms. The dermatologist necessarily prescribes a series of biochemical studies. Fluorocort is prescribed only if there are no bacteria, viruses, or fungi in biological samples.
Indications and contraindications
Fluorocort is used to eliminate the symptoms of pathologies sensitive to the effects of triamcinolone. It is recommended for patients with contact dermatitis, acute or chronic eczema. The medicine is prescribed for allergic rashes caused by bites or stings of non-poisonous insects.
The following diseases are also indications for the use of Fluorocort ointment:
- lichen planus of various etiologies and localizations;
- psoriatic rashes at any stage of pathology;
- Leiner's disease, or desquamative erythroderma;
- exfoliative erythroderma;
- otitis, uncomplicated by bacterial or fungal infection.
The drug is used in the treatment of neurodermatoses caused by neurological disorders. Fluorocort is not intended to eliminate skin manifestations of syphilis or tuberculosis. In pediatrics, it is used in children from 2 years of age only under the supervision of the attending physician.
The ointment is strictly prohibited for application to skin with open wound surfaces, cuts, and cracks. It is not used in the treatment of rosacea, diaper rash, acne vulgaris, trophic ulcers, or perioral dermatitis. Hypersensitivity to active and auxiliary ingredients also becomes an absolute contraindication.
Directions for use and doses
Fluorocort is applied in a thin layer to the affected areas of the skin 1-2 times a day. Single dosages are determined only by the attending physician, focusing on the degree of the inflammatory process. The patient’s age, a history of kidney and gastrointestinal pathologies, and the affected area are also taken into account. When using ointment in the treatment of children, it is usually mixed with a nourishing cream. The duration of the therapeutic course is 3-7 days.
Side effects and special instructions
The instructions for Fluorocort provide a detailed description of its possible side effects. Despite the rapid transdermal absorption, the glucocorticosteroid practically does not penetrate into the bloodstream. This becomes possible only when the drug is applied under occlusive dressings.
More often, a local allergic reaction develops or the symptoms of skin pathology worsen. There is a burning sensation, dryness, irritation, itching. There have been cases of secondary tissue infection, folliculitis, and hypopigmentation.
The product can be used under rigid and semi-rigid orthoses and elastic bandages. In these cases, the therapeutic effect of the drug is enhanced, but the risk of systemic side effects increases. If after 2-3 days of treatment the skin condition does not improve, you should consult a dermatologist. He will adjust the dosage regimen or replace Fluorocort with an analogue with a different active ingredient.
Fluorocort ointment – instructions for use, price, analogues
Anti-inflammatory, antipruritic hormonal agent. Application: psoriasis, neurodermatitis, eczema. Price from 201 rub.
Analogs: Triacort, Beloderm, Advantan. You can find out more about analogues, their prices, and whether they are substitutes at the end of this article.
Today we’ll talk about Fluorocort ointment. What is this product and how does it affect the body? What are the indications and contraindications? How and in what doses is it used? What can be replaced?
What kind of ointment
Fluorocort ointment is a hormonal drug. Intended for local treatment.
The medication has a pronounced antiallergic, antipruritic, anti-inflammatory and membrane-stabilizing effect.
Active ingredient and composition
The active substance is triamcinolone.
Additional components:
- stearic acid;
- liquid paraffin;
- purified water;
- methyl parahydroxybenzoate;
- polysorbate;
- glycerol
Liniment is white in color, has a uniform consistency and is practically odorless.
Pharmacological properties
The medication belongs to glucocorticosteroid drugs. It has a powerful anti-inflammatory, anti-allergic and anti-proliferative effect.
When exposed, the marginal accumulation of neutrophils is blocked, causing a slowdown in exudation. The migration of macrophages and the production of cytokines are stopped and granulation is reduced.
Vascular narrowing occurs, their permeability is restored due to stabilization of the membrane wall of lysosomes.
In cells, under the influence of glucocorticosteroids, lipocortin proteins are synthesized. As a result, the enzymatic activity of constituent substances that are actively involved in the production of arachidonic acid is inhibited. The amount of active endogenous components of the acid decreases.
Indications
Prescribed for the treatment of non-infectious skin pathologies. Indications for use are the need to eliminate:
What Fluorocort ointment is used for is indicated in the instructions supplied with the medication.
Directions for use and dosage
For adults, the medication should be applied several times a day to the affected area of the epidermis or under an occlusive dressing.
It is strictly forbidden to apply an occlusive dressing when treating small children.
In childhood, during pregnancy and pregnancy
It is allowed to be used to treat children from 2 years of age, but this should be done with extreme caution. The diaper, clothing and folds on the baby's skin can act as an airtight bandage and increase the rate of absorption.
It is necessary to take into account the ratio of the surface area of the epidermis, the weight of the patient and the insufficiently mature epidermis.
The course of treatment of children with Fluorocort ointment is no more than 5 days without an occlusive dressing.
The drug should not be used during the early stages of pregnancy. The decision on the need for use in later stages of pregnancy and during lactation is made by the attending physician.
The ratio of the possible risk to the child and the expected therapeutic effect must be assessed. Triamcinolone acetonide can pass into breast milk and affect the growth of the baby.
When treating children over 1 year of age, the product is applied in a thin layer to the inflamed area of the epidermis no more than 2 times a day. The course of therapy in childhood should not exceed 5 days.
Side effects
Local use of glucocorticosteroids may be accompanied by the development of adverse reactions that appear on the skin. If the drug is used for too long or when wearing an occlusive dressing, the functions of the adrenal cortex are inhibited.
When used, erythema, hypertrichosis and secondary infectious lesions may develop. May cause insomnia, headaches, cramps and dizziness. Possible development of heart failure, itching, burning of the skin and osteoporosis.
special instructions
What Fluorocort ointment helps with should be checked with your doctor. The drug should not be applied to large surfaces and it is important to avoid prolonged use in young children.
This product cannot be used in ophthalmology and should not be applied to the skin of the face.
To prevent infectious complications of a local nature, Fluorocort ointment can be prescribed simultaneously with antimicrobial agents.
It is not recommended to use the drug for the treatment of skin pathologies during pregnancy and lactation.
Overdose
In case of overdose, local and systemic reactions may occur with prolonged use of the medication over a large surface. It is necessary to gradually reduce the dose of the drug until complete withdrawal.
If signs of adrenal insufficiency appear, intravenous administration of hydrocartisone may be performed.
Customers' opinions
Although this drug is sold at a somewhat high price and is available with a prescription, the ointment is effective and popular among a large category of patients. The range of users is huge, which speaks in favor of Fluorocort. You can read reviews about the use and draw your own conclusion, but it’s still better to get checked, get tested and get an accurate diagnosis. In order not to harm your health even more, the patient should receive a prescription from a physician with the frequency, dosage and compatibility of different medications.
Elena from Vasilkov (25 years old): “I have been using this wonderful drug since adolescence. It always saved me from allergies that I suffered during the cold season. I lubricated the skin of my hands several times, after which the stains did not bother me for a long time. During pregnancy, I had to deal with Fluorocort again, as severe peeling and itching all over my body was simply annoying. The medications that were recommended for my situation did not help, the doctors prescribed this ointment from the second trimester. The medicine relieved the symptoms within a day, because the body began to get used to it. I had to alternate it with another medication.”
Lida from Sevastopol (53 years old): “After the onset of menopause, my whole body began to itch and itch. The doctor prescribed Fluorocort ointment. I was afraid that I was infected with some kind of dermatological disease, but in reality everything turned out to be much simpler. After a short course, the unpleasant symptoms stopped bothering me.”
Negative manifestations and overdose
The package insert for the drug describes in detail all possible side effects. It states that they develop infrequently, but they can happen. So, among the most common consequences of taking the following are the following:
- Pyoderma;
- In young people, skin atrophy is possible;
- Changes in blood pressure, inhibition of the pituitary-hypothalamic-adrenal system due to long-term use, especially when using an occlusive dressing;
- Osteoporosis;
- Mental pathologies;
- Glaucoma and cataracts;
- Increased risk of bone fracture;
- Change in glucose level;
- Slower growth of children.
There were no reports of overdose symptoms. But in case of using a large amount of ointment or prolonged use, the patient is advised to wash off the mass. If fluorocort ointment was taken orally, the patient's stomach should be rinsed and enterosorbents should be given before the medical team arrives.
Composition and effect of the drug
A white homogeneous mass without a distinct odor, in tubes of 15 grams in cardboard packs - it is in this form that Fluorocort is offered to patients. The active component has a concentration of 0.1%. The auxiliary components include the following substances:
- stearic acid;
- polysorbate;
- methyl parahydroxybenzoate;
- glycerol;
- paraffin;
- water;
- cetyl alcohol.
The active component of the drug is the substance triamcinolone, a synthetic fluorinated glucocorticosteroid. Its main property is the ability to actively fight inflammatory processes, along with this there is an antiallergic and antipruritic effect, which explains the advisability of topical use. The substance works as follows: it attaches to specific receptors in the cytoplasm and penetrates the nuclei of cells, where it interacts with their DNA. As a result of such actions, cells begin to produce lipocortin proteins, which in turn affect the production of inflammatory mediators, thereby allowing them to get rid of it.
After local application, the product easily penetrates the skin layers; it is found in the systemic bloodstream in particular. Some of the substances that enter the bloodstream are metabolized in the liver and excreted from the body within 10 hours.
Pharmacological action of Fluorocort
Thanks to the active components that make up Fluorocort, the drug helps reduce the manifestations of allergic reactions, inflammatory processes and itching, while performing an anti-exudative function.
Fluorocort and analogues of the drug have a vasoconstrictor effect, normalize vascular permeability due to stabilization of the lysosome membrane, and also affect the rate of division of epidermal cells towards its decrease.
The action of the drug is based on the mechanism of inhibition of the release of interleukin-1,2-interferon gamma from macrophages and lymphocytes. In addition, Fluorocort has an inhibitory effect on the release of inflammatory mediators by eozonophils, causes the formation of lipocortins and reduces the number of mast cells.
Fluorocort is a drug from the group of topical glucocorticosteroids. The drug contains the active substance triamcinolone, a synthetic fluorinated glucocorticosteroid. The drug has a pronounced anti-inflammatory, antiallergic, membrane-stabilizing and antipruritic effect and is used for the local treatment of dermatoses of non-infectious etiology. The mechanism of action of the drug is based on its ability to stimulate the synthesis of lipocortins.
special instructions
According to the instructions for use, there are a number of special instructions to help avoid deterioration of the patient's condition. A few important rules to remember when using the product:
- It is not recommended to use hormonal ointment during pregnancy and lactation (breastfeeding).
- The product is prohibited for use in ophthalmology.
- The drug should not be used on large areas of the skin or face.
- According to doctors, long-term use in children and adults should be avoided to avoid tissue atrophy.
- Glucocorticosteroid medication can be used simultaneously with antimicrobial agents (as prophylaxis in the presence of local infection).
For children
The drug is prescribed to children from the age of two, but when treating with ointment, extreme caution must be exercised. Folds on the baby's skin, diapers, and clothing can act as an airtight bandage and increase systemic resorption (absorption)
For the same reason, pediatricians recommend taking into account the ratio of the surface area of the skin, the weight of the child and the insufficiently mature epidermis. The duration of safe treatment for children is no more than five days, without the use of an occlusive dressing.
During pregnancy
It is prohibited to treat with the drug in the first trimester of pregnancy. Whether the ointment can be used in the second and third trimesters, as well as when breastfeeding, is decided by the attending physician. The specialist must seriously and carefully weigh the balance between the likely risk to the fetus and the expected therapeutic effect. When triamcinolone acetonide enters the bloodstream of a pregnant woman, it passes into the milk and affects the growth of the child and the adrenal cortex.
Is it possible to use fluorocort ointment for hemorrhoids?
- 1 mg - triamcinolone acetonide - active substance.
- 0.025 g - stearic acid;
- 0.002 g – methyl parahydroxybenzoate;
- 0.035 g - polysorbate 60;
- 0.18 g – 85% glycerol;
- 0.12 g – liquid paraffin;
- 0.06 g – cetyl alcohol;
- 0.577 g - purified water.
Ointment for external use 0.1% 15 g in a tube.
The package contains one tube of ointment.
Antipruritic, antiexudative, anti-inflammatory, antiallergic.
Fluorocort ointment belongs to the group of glucocorticosteroids (CGS) and is used for external use. It has local antiallergic, anti-inflammatory, antiproliferative and anti-edematous effects. When applied to the skin, it prevents the marginal accumulation of neutrophils, thereby reducing exudation and synthesis of cytokines , as well as helping to inhibit the migration of macrophages , which ultimately leads to a decrease in the development of granulation and infiltration.
Triamcinolone distributes quite quickly in body tissues.
The main metabolite of the active substance is 6-β-hydroxytriamcinolone.
It is excreted in equal proportions through the intestines and kidneys.
T1/2 of Triamcinolone from blood plasma is approximately 5 hours, from body tissues - 18-36 hours.
The use of Fluorocort ointment is recommended for skin diseases sensitive to treatment with glucocorticosteroids:
- neurodermatitis;
- chronic and acute eczema;
- contact dermatitis;
- psoriasis;
- lichen planus;
- Leiner's disease;
- exfoliative erythroderma;
- insect bites;
- external otitis (without infectious complications).
- rosacea;
- intertrigo;
- perioral dermatitis;
- acne vulgaris;
- trophic ulcer of the leg;
- open wounds and burns;
- infectious pathologies of the skin of a fungal, viral, bacterial nature (including skin tuberculosis);
- age up to 2 years;
- hypersensitivity to Triamcinolone or other components of the ointment.
Side effects when using Fluorocort are rare and are reversible.
When applying the drug, especially in large quantities, the following may occur:
- burning;
- dryness;
- irritation;
- itching;
- folliculitis;
- acneiform rash;
- hypertrichosis;
- perioral dermatitis;
- hypopigmentation;
- contact or allergic dermatitis;
- secondary infection;
- skin maceration;
- prickly heat;
- striae;
- skin atrophy.
The drug Fluorocort in the form of an ointment is used externally only.
It is recommended to apply the drug in a thin layer to problematic (according to indications) areas of the skin. The frequency of application of the drug is 2-3 times a day, at a maximum daily dose of 15 g.
The instructions for Fluorocort ointment allow the use of an occlusive dressing . In this case, applying 10 g of ointment is the maximum allowable amount per day.
The duration of treatment is usually 5-10 days. In severe cases, it can be used for up to 25 days. The maximum safe time for using the ointment is no more than 4 weeks.
A pronounced systemic effect of GCS , which is relieved by symptomatic therapy.
With the combined use of Fluorocort and oral glucocorticoids , the effect of the latter is enhanced.
At temperatures from 8 to 15 °C.
If you suspect any side effects, you must stop using Fluorocort and inform your doctor.
Like other glucocorticoids , Fluorocort is not applied to wound surfaces or to the skin in the eye area.
When using occlusive dressings or applying ointment on large surfaces, a systemic effect of the drug may occur. In this case, special caution is required, especially when treating pediatric patients.
If the diagnosed disease is complicated by the addition of a secondary fungal or bacterial infection, a specific antifungal or antibacterial drug should be added to treatment with Fluorocort ointment.
Particular attention is paid to the use of the drug on the skin of the face.
The use of Fluorocort in children requires special caution, since diapers or skin folds can act as an occlusive dressing , thereby increasing systemic resorption . For the same reason, when using the ointment in childhood, the ratio of body weight to skin surface, as well as lack of skin maturity, should be taken into account.
The recommended duration of therapy in children is no more than 5 days (do not use an occlusive dressing ). If necessary, subsequent treatment should be carried out under the supervision of a pediatrician.
Is fluorocort ointment hormonal or not?
Fluorocort ointment belongs to the group of glucocorticoids, which are steroid hormones produced by the adrenal cortex. Given topical use in small quantities, their effect on the body is minimal.
source
Fluorocort ointment is an affordable and effective anti-inflammatory drug that saves the skin from inflammation and dermatitis. In appearance, the medicine is a homogeneous, white, plastic mass without a characteristic odor, intended for external use. What is Fluorocort ointment used for, what are its pharmacological properties and contraindications, let's figure it out.
Antipruritic and antiallergic medicine is produced in tubes of 15 grams, packaged in cardboard boxes with attached instructions. The active ingredient of the ointment is triamcinolone acetonide. This is a synthetic corticosteroid - a hormone of the adrenal cortex. Accumulating in the epidermis, the substance relieves exudation, itching, swelling, allergic reactions, and inflammatory processes. To the question whether Fluorocort is a hormonal drug or not, the answer is unequivocal - yes. Auxiliary components of the ointment:
- stearic acid;
- methyl parahydroxybenzoate;
- cetyl alcohol;
- polysorbate 60;
- glycerol 85%;
- liquid paraffin;
- water is purified.
According to the instructions for use, topical fluorocort hormonal ointment helps neutralize even very complex allergic manifestations and reduce inflammation of the skin. Despite the fact that this drug belongs to the group of glucocorticosteroids, it is very quickly eliminated from the body without causing any negative effects. Indications for use of Fluorocort ointment:
- Neurodermatitis.
- Eczema.
- Psoriasis.
- Dermatitis of various etiologies.
- Keloid and hypertrophic scars.
- Photodermatosis.
- Lupus erythematosus.
- Various insect bites.
- Otitis externa.
- Haemorrhoids.
- Lichen planus.
The medicine does not have a systemic effect on the body due to poor absorption. To increase the absorption of the active substance, you need to make an occlusive dressing. The use of Fluorocort ointment with maximum effect is to apply a thin layer of the product to the affected area of skin 2-3 times a day, rubbing in with light massaging movements.
The course of treatment is prescribed by the doctor individually, depending on the severity of the pathology. The average duration of therapy is from 5 to 10 days. If the disease is severe, then treatment can be extended to 25 days, but not more than 4 weeks. It is not advisable to use a double dose of the medicine after a missed dose due to the risk of overdose.
The hormonal drug is contraindicated during pregnancy and while breastfeeding, in case of hypersensitivity to its components, fungal, viral or bacterial skin diseases. The ointment should not be used for children under 2 years of age, for burns or open wounds, for trophic ulcers of the lower leg, rosacea or vulgar acne.
Judging by patient reviews, Fluorocort is well tolerated if the shelf life and expiration dates of the drug are observed. But in case of overdose, adverse reactions of the body may occur, such as skin atrophy, steroid acne, increased growth of vellus hair, folliculitis, dryness, burning, skin irritation, prickly heat.
If you need to use the ointment to treat a child of any age or teenager, be sure to consult your pediatrician. Do not apply the corticosteroid to your face. Avoid prolonged use on large areas of skin. Do not use in ophthalmology. Combination with antimicrobial drugs is effective for infectious complications.
How much does Fluorocort ointment cost? The cost of the drug varies depending on where to buy (region). For example, in Russian pharmacies the price for a 15 gram tube ranges from 250 to 300 rubles. In Ukraine, the cost of the ointment is 80-90 hryvnia. If you purchase the drug in online pharmacies, it will cost a little less than in retail outlets in large cities such as Moscow or Kyiv.
If necessary, the drug is replaced with similar drugs. Effective analogues of Ftorokort ointment:
- Triacort. An ointment for systemic use that treats psoriasis, atopic dermatitis, bronchial asthma, chronic bronchitis, allergic diseases, and skin lesions of non-microbial origin.
- Polcortolon. It is used for severe endocrine and allergic diseases, for rheumatic and dermatological pathologies, as well as for chronic or alcoholic hepatitis.
- Kenalog. The hormonal agent is prescribed for neurodermatitis, dermatitis, lichen planus and lichen simplex, keloid scars and alopecia areata. The drug is effective for dermatoses accompanied by itching, burning, and weeping symptoms.
Elena, 24 years old : Although the hormonal ointment Fluorocort is not recommended by doctors during pregnancy, in my case it helped get rid of allergic rashes on my hands after I ate some exotic fruit. I tried everything I could to get rid of my allergies, but nothing helped. And from Fluorocort the inflammation went away after just three applications.
Ekaterina , 49 years old : Fluorocort ointment is the best remedy for acne and inflammation of the skin. It is enough to apply the drug only a couple of times a day to the problem area and the development of pathology stops very quickly. Just know that if acne is on the face, then the method of application is only spot-on, otherwise there may be side effects, since the ointment is hormonal!
Alexander, 41 years old : Fluorocort ointment, like all hormonal drugs, relieves dermatitis in a short time, but after a while the disease returns again. Its constant use leads to addiction, and exacerbations of the disease occur more often. I do not recommend treating chronic skin sores with the drug; it is better to look for methods of non-hormonal therapy.
source
External agents are the main ones in the treatment of skin pathologies. Fluorocort ointment is a glucocorticosteroid for topical use; the drug is used for the treatment of complex skin diseases of long-term duration. Not a first aid product. Action – anti-inflammatory, anti-allergic, relieves itching, prevents the development of tumor processes.
Fluorocort is a homogeneous, almost white ointment, odorless. Packaged in aluminum tubes of 15 g.
The main component is the synthetic glucocorticosteroid triamcinolone acetonide. Its content is 1 mg/g, that is, 0.1%.
Almost 85% of the composition is glycerol, among other components: liquid paraffin, water, stearic acid and others.
Reference: since the active component is GCS, Fluorocort is classified as a hormonal ointment.
Triamcinolone, like other hormones, has a pronounced effect on the rate of metabolic processes. Due to this, the membranes of mast cells are stabilized, the pathological proliferation of connective tissue is slowed down, which leads to the attenuation of inflammatory processes.
The rapid penetration of triamcinolone deep into the epidermis prevents the marginal accumulation of neutrophils, prevents the accumulation of fluid, and eliminates swelling.
Effect of triamcinolone on the body:
- Stimulates the production of lipocortins, which inhibit the synthesis of mediators of allergy and inflammation.
- Increases the rate of lipid metabolism.
- Reduces the production of histamine, which determines allergic manifestations.
- Regulates the permeability of vessel walls, ensuring timely outflow of fluid, stopping its accumulation.
- remove itching, burning;
- relieve pain, eliminate tightness or weeping;
- remove rashes and other skin manifestations;
- relieve swelling and redness.
Used in the treatment of acute and chronic skin pathologies with a long-term recurrent course. Belongs to the group of local corticosteroids of moderate activity (II).
Course use of Fluorocort improves blood supply to damaged skin areas. This improves tissue nutrition and accelerates local metabolic processes. The ointment stops granulation processes and prevents the development of infiltrates. As a result, it is possible to stop the formation of scars at the site of long-term damage to the epidermis.
What does the ointment help with? Fluorocort is used to treat:
- neurodermatitis;
- otitis externa;
- exfoliative erythroderma;
- eczema and psoriasis;
- acute and chronic dermatitis;
- lichen planus.
The ointment is used to treat insect bites complicated by an allergic reaction.
The drug Fluorocort is not able to eliminate bacterial or viral infection, therefore, in case of infection, additional medications are used for therapy.
Recommended for use by children, including boys, from 2 years of age.
It is excreted by the intestines and kidneys; complete elimination requires 18 to 36 hours.
For external use only.
The ointment is applied in a thin layer 2-3 times a day to previously washed and dried areas of the skin. The total daily dose of Fluorocort is no more than 15 g. The use of occlusive dressings is allowed, but the amount of the drug should be reduced to 10 g.
In accordance with the instructions for use, the course of therapy with Fluorocort ointment is 5-10 days. It is allowed to treat complicated cases with a longer course of up to 25 days, no more than 28. The course can be extended only if there are positive dynamics.
Let's highlight a few main points when using that you need to pay attention to:
- Do not apply to skin near eyes.
- Avoid contact with open wounds.
- After application, wash your hands well.
- Using bandages increases the risk of side effects. This must be remembered when using the medicine for children. Clothing can have the effect of a bandage on delicate skin.
- The recommended course for children is 5 days.
- When applying the ointment to a large area over a long course, a systemic effect of glucocorticosteroids is possible.
- A long course can provoke skin infection due to a decrease in local immunity; antibacterial or antimycotic therapy should be included.
All reactions should be reported to your doctor so treatment can be adjusted.
The ointment is not used for the following diseases and conditions:
- children under 2 years old;
- in case of individual intolerance to any of the components of the drug;
- for bacterial, viral, parasitic skin diseases;
- for damage to the epidermis caused by syphilis and tuberculosis;
- dermatitis of the perioral area (perioral);
- acne – pink, vulgar;
- diaper dermatitis in babies;
- trophic ulcers, wounds.
Fluorocort is not used for mucous membranes of the eyes.
Whether to prescribe a medicine is decided individually in each case. Recommendations for pregnancy and lactation are as follows:
- assessment of benefit/risk indicators for mother and fetus;
- If therapy is necessary, breastfeeding is stopped.
They try to replace GCS for pregnant women with safer medications.
The risk of side effects from the use of Fluorocort is increased in patients with the following diseases:
- diabetes;
- gastrointestinal ulcers;
- hypertension;
- cardiac, renal, liver failure;
- mycoses, bacterial and viral infections.
The use of Fluorocort in these cases is carried out with monitoring of the condition and blood parameters.
Possible negative manifestations:
- itching, burning;
- tightness of the epidermis, dryness;
- weakening of pigmentation;
- prickly heat;
- hives;
- perioral dermatitis;
- hypertrichosis;
- skin infection;
- stretch marks, thinning of the epidermis.
With long-term use together with GCS in the form of injections or oral administration, the risk of negative reactions increases.
Important: store Fluorocort at a temperature of 8-15 °, that is, in the refrigerator.
The cost of the ointment in pharmacies is from 220 rubles, manufactured in Hungary.
Triamcinolone acetonide is contained in the following preparations:
- Polcortolon. Available in the form of ointment, tablets and aerosol. Contains the same dose of the active substance in the ointment – 0.1%. Scope of application: severe forms of psoriasis, eczema, dermatitis of various etiologies.
- Triacort. The content of the active substance in the ointment is 0.1%. Used in complex therapy.
If you are allergic to the active substance, you can choose an analogue of Fluorocort with a similar therapeutic effect. Other ointments containing GCS:
- Lokoid. Contains hydrocortisone, which is a weaker corticosteroid and therefore has fewer side effects.
- Dermovate. It has two external forms - cream and ointment. It relieves swelling and itching well. Manufacturer: Poland, price – from 300 rubles.
- Advantan. The ointment is used in the treatment of skin pathologies with increased dryness of the epidermis. Allowed for use by children from 4 months.
- Akriderm. It is used for dermatitis of allergic and non-allergic nature, has a vasoconstrictor effect.
Other ointments with similar properties: Afloderm, Beloderm, Betamethasone, Betliben.
Independent replacement of drugs with analogues is not recommended.
Fluorocort is a reliable treatment for skin pathologies. According to patient reviews, the ointment rarely has side effects if the recommended dosage and course are not exceeded. GCS are often the only way to cure a serious disease that is not responsive to other drugs.
source
Fluorocort is a drug from the group of glucocorticosteroids.
Thanks to the active components that make up Fluorocort, the drug helps reduce the manifestations of allergic reactions, inflammatory processes and itching, while performing an anti-exudative function.
Fluorocort and analogues of the drug have a vasoconstrictor effect, normalize vascular permeability due to stabilization of the lysosome membrane, and also affect the rate of division of epidermal cells towards its decrease.
The action of the drug is based on the mechanism of inhibition of the release of interleukin-1,2-interferon gamma from macrophages and lymphocytes. In addition, Fluorocort has an inhibitory effect on the release of inflammatory mediators by eozonophils, causes the formation of lipocortins and reduces the number of mast cells.
According to the instructions, Fluorocort is available in the form of an ointment for external use. The main active ingredient is triamcinolone acetonide, the mass fraction of which is 0.1%. Fluorocort ointment is a homogeneous substance of light, almost white color, without a distinct odor. The product is packaged in an aluminum tube weighing 15 g, which is placed in a cardboard box.
Medical reviews of Fluorocort prescribe taking the drug as a medicine for the following diseases:
- for psoriasis;
- for eczema;
- for neurodermatitis/atopic dermatitis;
- for photodermatoses;
- for dermatitis of various origins (including allergic);
- for the treatment of hypertrophic and keloid scars;
- with lichen planus;
- with discoid lupus erythematosus;
- in case of irritation from insect bites.
Before starting to use the drug, the instructions for Fluorocort recommend that you familiarize yourself with the list of contraindications in order to avoid complications. You should refrain from using Fluorocort in the following cases:
- in the presence of skin diseases of various etiologies (including viral, bacterial and fungal);
- in case of diagnosed skin tuberculosis;
- with skin manifestations of syphilis;
- for precancerous skin diseases and other types of tumors;
- in the presence of hypersensitivity to the components of the Fluorocort composition;
- with perioral dermatitis.
The drug is an external topical application. In accordance with numerous reviews of Fluorocort, the treatment regimen described below is recommended.
The ointment must be applied in a thin layer to damaged areas of the skin with a frequency not exceeding 3 times. The amount of ointment used for applications should not exceed 15 g per day. If necessary, the ointment can be applied under an occlusive (sealed) dressing. The recommended amount of ointment in such situations is 10 g or less.
The course of treatment with Fluorocort is from 5 to 10 days. In rare cases, an extension of up to 25 days is possible. However, the drug should not be used for longer than 4 weeks.
The use of the drug may lead to unwanted side effects. Following the instructions for Fluorocort, in such situations it is necessary to contact your doctor, describing in detail the disturbing symptom.
Local adverse reactions include the following:
- development of erythema;
- hypertrichosis;
- the appearance of secondary infectious infections in the form of fungal and/or bacterial infections.
Long-term use of the drug or its application to large areas of the skin can lead to undesirable effects in the form of atrophic skin changes and a number of others characteristic of drugs of the GCS group.
In addition, Fluorocort can cause allergic reactions.
The drug is not recommended for use by pregnant women and women during lactation.
Fluorocort should not be applied to large surfaces of the body or facial skin, and its long-term use in children of any age should be avoided.
It is not recommended to use the product in ophthalmology.
It can be used in conjunction with antimicrobial drugs as a prophylactic agent for local infections.
Among the drugs similar in composition and mode of action to Fluorocort, the most well-known are the following:
- Berlicourt;
- Kenacort;
- Azmacort;
- Kenalog;
- Polcortolon;
- Triacort;
- Triamcinolone.
It is recommended to store fluorocort in a dark place where the temperature does not exceed 15°C. The shelf life in this case is 2 years.
Fluorocort 0.1% ointment for external use 15 g 1 pc.
Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!
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In the UK there is a law according to which a surgeon can refuse to perform an operation on a patient if he smokes or is overweight. A person must give up bad habits, and then, perhaps, he will not need surgical intervention.
The human brain weighs about 2% of the total body weight, but it consumes about 20% of the oxygen entering the blood. This fact makes the human brain extremely susceptible to damage caused by a lack of oxygen.
A person taking antidepressants will, in most cases, become depressed again. If a person has coped with depression on his own, he has every chance to forget about this condition forever.
American scientists conducted experiments on mice and came to the conclusion that watermelon juice prevents the development of vascular atherosclerosis. One group of mice drank plain water, and the second group drank watermelon juice. As a result, the vessels of the second group were free of cholesterol plaques.
In order to say even the shortest and simplest words, we use 72 muscles.
Human bones are four times stronger than concrete.
In an effort to get the patient out, doctors often go too far. For example, a certain Charles Jensen in the period from 1954 to 1994. survived more than 900 operations to remove tumors.
Four pieces of dark chocolate contain about two hundred calories. So if you don’t want to gain weight, it’s better not to eat more than two slices a day.
Smiling just twice a day can lower your blood pressure and reduce the risk of heart attacks and strokes.
The first vibrator was invented in the 19th century. It was powered by a steam engine and was intended to treat female hysteria.
According to many scientists, vitamin complexes are practically useless for humans.
Research shows that women who drink several glasses of beer or wine per week have an increased risk of developing breast cancer.
People who eat breakfast regularly are much less likely to be obese.
Most people learn basic dental hygiene from a very early age. After all, teeth serve several purposes, and they are all important to varying degrees. Ability
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Many patients suffering from enlarged hemorrhoids wish to get rid of unpleasant symptoms without surgery - with the help of conservative therapy. Antihemorrhoidal drugs are available in various dosage forms. One of the most common and effective is an ointment.
The effectiveness of local medications lies in the fact that they quickly act on hemorrhoids, stop bleeding without affecting the digestive tract. What ointments to use for hemorrhoids should be determined by the attending physician.
Antihemorrhoidal ointments are a mild type of pharmaceutical that are intended primarily for application to external cavernous formations, but in some cases they are also introduced into the anus.
Ointment products differ in the content of active ingredients, which determine the main properties of the drugs. The basis of ointments are substances such as petroleum jelly or lanolin.
Ointments for hemorrhoids are easy to use and are suitable for the treatment of both internal hemorrhoids and external cavernous formations. The drugs act locally, which helps to avoid or minimize the development and spread of allergic reactions.
This form of the medicine penetrates deeply into the skin and mucous membrane, allowing the active ingredients to act inside the hemorrhoids, which speeds up relief from the negative symptoms of the disease.
Important! As patient reviews show, ointments have a drawback - due to the oily base, the preparations cannot be completely absorbed into the skin, so they often leave unpleasant greasy stains on clothes.
However, it should be understood that ointment products are not suitable for monotherapy. Locally acting medications should be part of a comprehensive treatment, increasing the effectiveness of the main methods of getting rid of hemorrhoids.
Therapy with ointment products has certain features, which presupposes compliance with the rules for using these drugs in the treatment of hemorrhoids.
- Before using the ointment, the patient should, if possible, empty the intestines and treat the anal area (rinse with water and wipe with a soft cloth).
- For external hemorrhoids, a thin layer of ointment is applied to cavernous formations located in the tissues of the anorectal area. For internal venous collections, the medication should be injected into the rectum using a finger, a cotton swab, or a special applicator.
- Frequency of use – 2-3 times a day or after each bowel movement. When the symptoms gradually subside, doctors recommend using the ointment no more than once a day.
- Drugs that contain hormones must be used extremely carefully and not for a very long time. In addition, such ointments should be discontinued gradually.
- The duration of therapy is individual in each specific case. Most often it does not exceed 7 days. Heparin ointment may be prescribed for a two-week treatment course.
- Ointment products are stored in a cool and dark place. In the summer months, it is generally better to put tubes of medications in the refrigerator. The period of application usually does not exceed three years.
Ointment products are stored in a cool and dark place.
When using the product for the first time, the patient needs to monitor the body’s reaction. If redness, rash and other consequences are observed at the application site (photos of negative reactions are available on the Internet), the drug is discontinued and therapy is adjusted.
Ointments for the treatment and prevention of varicose veins of hemorrhoidal veins are divided into several categories. The classification depends on the main focus of the active components.
In most cases, the effect of ointment alone is completely insufficient. To obtain a pronounced therapeutic effect, it is necessary to combine therapy with local and systemic medications.
This group includes drugs that inhibit blood clotting and reduce the likelihood of blood clots. The most famous medication in the category is Heparin ointment for the treatment of external hemorrhoids.
Heparin ointment is used to treat external hemorrhoids.
Also typical anticoagulants are Gepatrombin, Gepatrombin G.
This remedy is useful if the patient needs an inexpensive and truly effective ointment for hemorrhoids, which has an antithrombotic and antihemorrhoidal effect. The main advantage of the drug is its low cost.
The heparin component prevents the formation of blood clots, anesthesin (anesthetic agent) relieves pain, and benzyl nicotinate promotes vasodilation, which helps other ingredients penetrate the hemorrhoid.
Among the restrictions are:
- necrosis of tissues and mucous membranes;
- low blood clotting;
- first 12 weeks of gestation.
It is extremely rare for patients to experience bleeding; more often, undesirable consequences such as itching, allergic dermatitis or urticaria may develop.
The cost of the medicine is from 35 to 80 rubles.
The product is intended for the treatment and prevention of blood clots, and has the ability to regenerate tissue.
Hepatrombin is intended for the treatment and prevention of blood clots and has the ability to regenerate tissue.
Heparin, the main active ingredient, is able to accumulate in the inner layers of the skin and penetrate through the vascular membranes.
Ointment for the treatment of Gepatrombin is contraindicated in:
- constant bleeding;
- a decrease in the number of platelets in the blood;
- the first 12 weeks of gestation.
The drug is well tolerated; in rare cases, hypersensitivity reactions to the ingredients of the product in the form of skin redness are possible.
Price - from 120 to 250 rubles, depending on the amount of the active ingredient in the product.
The medication relieves blood clots and inflammation in hemorrhoids.
Hepatrombin G relieves blood clots and inflammation in hemorrhoids.
The heparin component prevents blood clotting, prednisolone reduces swelling, inflammation, and itching in the anal area. Lauromacrogol promotes sclerization, that is, gluing, of vascular walls.
The drug helps against external hemorrhoids and internal venous accumulations, which are accompanied by severe inflammatory processes and thrombophlebitis of the anal veins.
Hepatrombin G has more contraindications than the classic version of the drug:
- infectious lesions of the skin;
- predisposition to bleeding;
- syphilitic and tuberculous lesions of the rectum;
- anal tumor.
The most common side effects are local allergic reactions in the area of application - itching and redness of the skin.
The price of the drug is from 160 to 190 rubles.
Another anticoagulant drug with a pronounced antihemorrhoidal effect.
What cheaper analogues exist?
Along with the drug described, there is also a huge number of ointments, which will contain components that coincide with the composition of Fluorocort. Thus, it is necessary to note cheaper ointments of similar action, which are based on the same active substance as in the product in question:
- Kenalog;
- Advantan;
- Tricortal;
- Sinaf;
- Polcortolon, etc.
They all have the same range of possible uses and limitations. If the active substance itself is not suitable for the patient, then only a doctor can prescribe another drug for therapy.
Side effects and overdose
Glucocorticosteroid medications that are applied topically, in some cases cause side effects that appear on the skin. True, according to reviews, there is a possibility of systemic side effects, which depends on the amount of the active substance that enters the patient’s blood. If the ointment is used for a long period of time on a large surface of the skin or an occlusive dressing is often used, then the function of the adrenal cortex is suppressed (mainly in children). Other adverse reactions:
- CNS (central nervous system): mental pathologies, insomnia, headache, convulsions, anxiety, dizziness, increased intracranial pressure.
- Immune system: hypersensitivity.
- Digestive system: pancreatitis, gastric and/or intestinal bleeding, peptic ulcer, esophagitis.
- Cardiovascular system: arterial hypertension, development of heart failure.
- Skin reactions: dryness and thinning of the epidermis, dermatitis, erythema, itching, burning, folliculitis, hirsutism, hypertrichosis, erythema, diaper rash, hypopigmentation.
- Water-electrolyte metabolism: hypokalemia, disruption of the adrenal cortex, sodium and water retention in the body, hypokalemic alkalosis.
- Musculoskeletal system: osteoporosis (osteonecrosis), growth retardation (in a child), aseptic necrosis, steroid myopathy.
- Visual organs: development of glaucoma, cataracts, exophthalmos, corneal ulcer, swelling of the optic nerve nipple.
- Infectious, parasitic diseases: opportunistic infections, activation of “dormant” (latent) infectious pathologies.
- Deviations in laboratory tests: negative indicators of nitrogen balance, increased intraocular pressure, suspension of reactions during skin tests.
Side effects
For glucocorticosteroid drugs with musculoskeletal constipation, there are characteristic side effects of a musculoskeletal nature, however, due to the amount of molecule that enters the systemic bloodstream, systemic effects are possible.
If the measles are stuck on a large surface, the function of the measles of the nasal glands may be suppressed, especially in children, as well as when the occlusive dressings are stuck; Possible negative nitrogen balance of inheritances due to increased protein breakdown.
Additional words with a known effect: cetyl alcohol - may cause local skin reactions (for example, contact dermatitis); Methyl parahydroxybenzoate (E 218) - may cause allergic reactions (possibly intensified).
Infections and parasitic diseases:
activation of latent infections, masking of infection, opportunistic infections.
On the side of the immune system:
hypersensitivity reactions.
On the side I will exchange speeches and food:
Suppressed function of the measles of the supraginae (secondary measles deficiency), hypokalemia alkalosis, water and sodium retention in the body, hypokalemia.
Mental disorders:
sleeplessness.
On the side of the central nervous system:
mental disorders, seizures, confusion, headache, displacement of the internal cranial pressure.
From the side of the organs:
cataract*, posterior subcapsular cataract, exophthalmos, glaucoma, papilla of the visual nerve, corneal bulge. *Importance of development of cataracts in children.
On the side of the heart:
heart failure.
From the side of the vessel:
arterial hypertension.
On the side of the scolio-intestinal tract:
Schulkovo-intestinal hemorrhage, Schlunovo-intestinal hemorrhage, Schulno-intestinal perforation, esophagitis, pancreatitis, peptic virulence.
On the side of the skin and under the skin fabrics:
dermatitis, liver irritation, foliculitis, acneform rashes, contact dermatitis, dryness and thinness of the skin, erythema, hirsutism, hypersweating, hair loss, itching, skin atrophy, hypopigment atsia, twitching, striae, telangiectasia, worsening of wounds.
On the side of the musculoskeletal apparatus and suitable tissue:
growth retardation in children, steroid myopathy, osteoporosis, osteonecrosis, aseptic necrosis.
Laboratory equipment:
increased internal pressure, negative nitrogen balance, increased reaction to skin tests.