How to take Venter for gastritis

Venter is prescribed for a number of diseases accompanied by damage to the gastric mucosa. The drug gives a favorable prognosis when used correctly. The medication has a number of contraindications and side effects, so it is important to read the instructions before starting treatment.

• Composition and release form
• Indications for use
• Contraindications
• special instructions
• How to take it correctly
• What side effects may occur?
• Terms of sale
• Possible substitutes for Venter - table

  Popular gastroprotectors - photo gallery

What is Venter?

Venter belongs to the group of gastroprotectors - drugs that promote the regeneration of the gastric mucosa. The Latin name is Venter. The medication prevents the aggressive effects of hydrochloric acid, forming a protective shell on the ulcer surface. Additionally neutralizes pepsin and bile acids, which contribute to the destruction of the mucous layer. Such properties of the drug create favorable conditions for accelerating the healing of damaged areas and preventing the progression of the disease.

Venter promotes healing of ulcers

The drug is absorbed from the gastrointestinal tract only in small quantities (no more than 5%). 90% is excreted through the intestines and only 10% enters the bloodstream and is evacuated through the kidneys.

Pharmacological properties

The instructions for Venter indicate that the drug protects the gastric mucosa by reducing the activity of the enzyme pepsin and binding bile salts.

Sucralfate dissolves in an acidic environment and binds to the proteins of dead tissue in the area of ​​the ulcer. As a result, an adhesive polymer paste with alkaline properties is formed. Venter protects the affected areas of the mucosa from the influence of bile, pepsin and hydrochloric acid for 6 hours. The interaction of the drug with healthy areas of the mucous membrane is insignificant.

Only 5% of sucralfate can be absorbed into the blood, so it does not have a systemic effect. The drug is excreted from the blood by the kidneys, and the non-adsorbed part in the intestine is excreted in the feces.

Venter accelerates the scarring of stomach and small intestinal ulcers and reduces the absorption of phosphates into the blood.

Composition and release form

This medication is available in tablet form. The active substance and main component is sucralfate. Auxiliary ingredients:

• corn starch;
• talc;
• anhydrous colloidal silicon dioxide;
• magnesium stearate.

For stomach ulcers, sucralfate forms a protective film on the surface of the defect

Additional instructions

A short course of treatment helps to achieve scarring of a stomach or duodenal ulcer, but the gastroprotector does not in any way affect the severity and frequency of relapses.

If sucralfate is administered to a patient through a tube, it is possible that a spherical calculus may form in the gastrointestinal tract due to the binding of proteins present in enteral nutrition solutions.

Patients suffering from renal dysfunction require periodic monitoring of phosphate and aluminum levels in the blood.

During the course of treatment, driving and working with other potentially dangerous mechanisms is allowed, since the active substance does not affect the speed of psychomotor reactions.

Indications for use

The drug is prescribed in the presence of ulcerative defects of the mucous membrane of the stomach and duodenum, which can be caused by:

• errors in diet;
• stress;
• taking certain groups of drugs (salicylates, NSAIDs, etc.);
• alcohol abuse.

The medication is used to treat gastritis with increased secretion, heartburn, as well as for the treatment of diseases associated with the reflux of acidic stomach contents into the esophagus (reflux esophagitis, motility disorders, reflux gastritis).

Reflux esophagitis is an indication for the use of Venter

The active substance helps get rid of excess amounts of phosphates associated with intoxication in renal failure.

Venter

In this medical article you can familiarize yourself with the drug Venter. The instructions for use will explain in what cases granules or tablets can be taken, what the medicine helps with, what are the indications for use, contraindications and side effects. The annotation presents the forms of release of the drug and its composition.

In the article, doctors and consumers can only leave real reviews about Venter, from which one can find out whether the medicine has helped in the treatment of gastric and duodenal ulcers in the acute stage in adults and children, for which it is also prescribed. The instructions list analogues of Venter, prices of the drug in pharmacies, as well as its use during pregnancy.

Venter is a gastroprotective medicine. Instructions for use confirm that 1 gram tablets and granules for preparing a solution protect the mucous membrane of the stomach and duodenum from the aggressive effects of hydrochloric acid, bile and pepsin.

Release form and composition

The drug is available in the following dosage forms:

• Tablets, 10 pcs. in blister packs, 5 or 10 packs in a cardboard box;
• Granules for oral administration, in sachets, 50 sachets in a cardboard box.

The drug contains the active substance – sucralfate, in the amount of:

• 1 tablet – 0.5 g or 1 g;
• 1 sachet – 1 g.

Indications for use

What does Venter help with? Granules and tablets are prescribed for the treatment of:

• reflux esophagitis;
• and prevention of exacerbations of gastric and duodenal ulcers;
• prevention of stress ulcers;
• hyperphosphatemia in patients with uremia who are on hemodialysis.

Instructions for use

Venter tablets are taken orally whole (not chewed or crushed), washed down with a sufficient amount of liquid. If swallowing a whole tablet is difficult, you can dissolve it in 100 ml of drinking water. Take it one hour before meals and before bedtime.

The granules must be pre-dissolved in water.

The prepared solution should be taken 30-60 minutes before meals. The duration of therapy is determined by a specialist, taking into account the complexity of the disorder and the individual characteristics of each patient.

• For adult patients, the daily dosage is 2 tablets or 2 sachets - one taken before lunch, the second before bed.
• Adults are recommended to take 0.5–1 g of the drug 4 times a day, 1 g twice a day, or 2 g twice a day.
• To prevent stress ulcers, 1 g of sucralfate is recommended 6 times a day.
• To prevent relapse of peptic ulcer, 1 g is used twice a day.
• The maximum daily dose should not exceed 8 g.

The duration of treatment for peptic ulcer disease is on average 4–6 weeks. According to indications, treatment can last up to 12 weeks.

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Contraindications

The drug is not prescribed for severe renal impairment, as well as in the presence of obstruction in one of the gastrointestinal tracts and diseases of the esophagus that cause difficulty in swallowing food. The medication is contraindicated for use in gastrointestinal bleeding. The same remark applies to individual intolerance to the active substance.

During pregnancy and breastfeeding, the drug is prescribed if absolutely necessary and with caution. Children can take the medicine from 4 years of age.

Severe stage of renal failure is a contraindication to the use of Venter

If the stool suddenly becomes liquid and takes on a dark color, this may be a signal of gastrointestinal bleeding. In this case, before taking the drug, you should definitely consult a gastroenterologist.

Drug interactions

According to the instructions, Venter in combination with antacid medications should be taken at intervals of at least half an hour.

The use of Venter in combination with medications that contain aluminum increases the likelihood of aluminum accumulation in the body. To avoid this, it is recommended to take Venter analogues.

When used in combination, Venter can reduce the absorption of ranitidine, tetracyclines, digoxin, cimetidine, and ketoconazole. If there is a need for simultaneous use of these drugs, an interval of at least two hours should be maintained.

Patients who are fed through a gastric tube are recommended to take Venter separately from food and other medications.

special instructions

Medicines containing sucralfate should not be combined with antacids. It is recommended to maintain a half-hour interval between taking medications. It is not advisable to combine this medication with the following medications:

• anticoagulants;
• antibiotics from the group of fluoroquinolones and tetracyclines;
• amitriptyline;
• digoxin;
• antifungal drugs;
• theophylline;
• ranitidine and its analogues;
• phenytoin and sulpiride;
• Hindi.

A short course of therapy with this medication promotes complete healing of the ulcer, but does not reduce the risk of relapse. It is not recommended to combine the medicine with alcohol, as tissue regeneration slows down and the risk of bleeding from the gastrointestinal tract is high.

If symptoms of drowsiness and convulsions occur during treatment, this may indicate a toxic effect, which most often occurs in persons with renal failure. In such cases, monitoring of aluminum and phosphates in the blood is necessary, as well as dose revision.

Drowsiness and seizures may indicate toxic effects of therapy

The active ingredient of the drug binds protein, so when the drug is administered through a tube along with nutritional mixtures, there is a possibility of the formation of a small calculus.

VENTER

Pills

white, oval, with a notch on both sides.

Excipients: corn starch, talc, colloidal anhydrous silicon dioxide, magnesium stearate.

10 pieces. – blisters (5) – cardboard packs.

pharmachologic effect

Gastroprotective agent. By interacting with the proteins of necrotic ulcer tissue, it forms a protective layer that prevents the further destructive effect of pepsin, hydrochloric acid and bile salts. Increases prostaglandin synthesis, reduces pepsin activity and binds bile salts. Inhibits pepsin activity by 30%. Has a weak antacid effect.

Being in the stomach and duodenum, it is transformed into a polyanion with many free negative charges, which form strong bonds with positive radicals of protein-like exudate (albumin, fibrinogen) of the mucous membrane. Interaction with unchanged mucous membrane is insignificant.

Pharmacokinetics

Absorption is low - 3-5% of the administered dose (up to 5% of the disaccharide component and less than 0.02% of aluminum). Excreted through the intestines – 90% unchanged; a small amount of sulfate disaccharide that enters the bloodstream is excreted by the kidneys.

Indications

Peptic ulcer of the stomach and duodenum in the acute phase, symptomatic ulcers, stress ulcers of the gastrointestinal tract, erosive and ulcerative lesions of the gastrointestinal tract associated with taking NSAIDs; hyperacid gastritis, reflux esophagitis, reflux gastritis, gastroduodenitis, heartburn, drug ulcer.

Hyperphosphatemia in uremic patients on hemodialysis.

Contraindications

Severe renal dysfunction, dysphagia or gastrointestinal obstruction, gastrointestinal bleeding, hypersensitivity to sucralfate.

Dosage

Orally for adults, 0.5-1 g 4 times a day, or 1 g in the morning and evening, or 2 g 2 times a day, 1 hour before meals and before bedtime. Maximum daily dose

is 12 g. The average duration of treatment for peptic ulcer is 4-6 weeks, if necessary - up to 12 weeks. Children – 0.5 g 4 times a day.

In patients with hyperphosphatemia, when plasma phosphate concentrations decrease, the dose of sucralfate may be reduced.

From the digestive system:

constipation, diarrhea, nausea, dry mouth, gastralgia.

From the side of the central nervous system:

drowsiness, dizziness, headache.

Dermatological reactions:

skin itching, rash, urticaria.

Other:

pain in the lumbar region.

Drug interactions

When used simultaneously with indirect anticoagulants, their anticoagulant activity (including warfarin) may decrease.

With simultaneous use, the absorption of antimicrobial agents of fluoroquinolone derivatives is reduced.

With simultaneous use, the absorption of amitriptyline is reduced, which may lead to a decrease in its clinical effectiveness.

It is believed that with simultaneous use, the formation of chelate complexes with amphotericin B sucralfate, colistin sulfate, and tobramycin is possible, which can lead to a decrease in their antimicrobial activity.

When used simultaneously with digoxin, the absorption of digoxin may be reduced.

It is believed that with simultaneous use there may be a slight decrease in the absorption of ketoconazole and fluconazole.

When used simultaneously with levothyroxine, the effectiveness of levothyroxine is noticeably reduced.

When used concomitantly with sucralfate, slight changes in the pharmacokinetics of theophylline were observed. It is also believed that there may be a significant reduction in the absorption of theophylline from sustained release dosage forms.

It is believed that with simultaneous use, a decrease in the absorption of tetracycline is possible.

With simultaneous use, the absorption of phenytoin and sulpiride decreases.

A case has been described of a decrease in the concentration of quinidine in the blood plasma when used simultaneously with sucralfate.

With simultaneous use, a slight decrease in the bioavailability of cimetidine, ranitidine, and roxatidine cannot be ruled out.

special instructions

If simultaneous use of antacids is necessary, they should be taken 30 minutes before or 30 minutes after taking sucralfate.

In case of renal failure, monitoring of serum aluminum and phosphate concentrations is necessary.

The appearance of drowsiness and convulsions may indicate manifestations of the toxic effects of aluminum.

Short-term treatment can lead to complete scarring of the ulcer, but does not change the frequency and severity of relapses of peptic ulcer disease after scarring.

The administration of sucralfate through a nasogastric tube may lead to the formation of a bezoar (a stone formed in the digestive tract and shaped like a ball) with other drugs or enteral nutrition solutions, because. sucralfate can bind protein.

Pregnancy and lactation

Use with caution during pregnancy and lactation.

For impaired renal function

Contraindicated in severe renal impairment.

The description of the drug VENTER is based on officially approved instructions for use and approved by the manufacturer.

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Source: https://health.mail.ru/drug/venter/

What side effects may occur?

When treated with this medication, you may experience discomfort in the stomach, as well as nausea, changes in stool (diarrhea or constipation) and dry mouth. Sometimes headaches and drowsiness occur during therapy. In rare cases, allergic reactions are possible, accompanied by skin rashes and itching. During treatment, dizziness and pain in the lumbar region sometimes appear.

By following the doctor's instructions and dosage, the likelihood of side effects decreases.

Side effects

According to reviews, Venter is generally well tolerated by patients. In isolated cases, the following side effects may develop:

• Gastrointestinal tract: stool disorders, nausea, vomiting, dry mouth, flatulence;
• Central nervous system: disturbance of sleep and wakefulness, vertigo, dizziness. According to reviews, Venter, when used for a long time in patients with impaired renal function, can cause the accumulation of aluminum and the development of encephalopathy;
• Allergies: skin rash, itching, urticaria;
• Other reactions: lower back pain, myalgia.

Possible substitutes for Venter - table

Popular gastroprotectors - photo gallery

De-Nol promotes the healing of ulcerative defects

Vikair accelerates the regeneration of the gastric mucosa

Vikalin is prescribed to persons over 18 years of age

Venter: how to take the drug

It is recommended to be administered orally to adults and children over 14 years of age on an empty stomach, half an hour or 1 hour before meals. The tablets can be swallowed whole with water, or dissolved in ½ glass of water and drunk.

Prevention of relapse of Helicobacter pylori - negative duodenal ulcer.

• 1 tablet 2 times a day. The drug should be taken for 4-8 weeks after the ulcer has healed.

Prevention and treatment of stress ulcers.

• 1 tablet 6 times a day. The maximum daily dose is 8 g of sucralfate (8 tablets). The drug can be taken safely for at least 2 weeks.

Gastroesophageal reflux disease.

• 1 tablet 4 times a day: 1 tablet before each main meal (breakfast, lunch, dinner) and 1 tablet immediately before bed. The course of treatment is up to 12 weeks.

The drug should not be used to treat children under 14 years of age.

Reviews of the drug Venter for the treatment of gastritis

Alisa Shilova May 9, 2020: saved me from severe stomach pains, chronic gastritis worsened, I couldn’t sleep at night from the severe pains! The only negative is that it is very difficult to swallow! I had to divide it into several parts, or even make suspensions (due to the peculiarities of the stomach). But they helped nonetheless.

Venter tablets saved me from severe stomach pains

Olga Agafonova April 26, 2020 10:58 pm: very large tablets, it’s simply impossible to swallow! Although the instructions say to swallow without chewing. I tried to swallow the pill, water came out of my nose, I could barely swallow it! I only swallow small pieces! Explain what will happen if you take it this way?

Anton Khvalovsky February 25, 2020, 03:49: the drug is good, but the form…. I don’t know which is easier to swallow—school chalk from the blackboard or Venter in tablets? You can ask someone to spit down your throat through a tube, like giving a horse a pill.

Viktor Aleksandrovich Smirnov March 17, 2020, 09:36: in the treatment of chronic gastritis, I took various medications: Losek, Nolpaza, omeprazole, denol, and it did not help. The doctor advised me to take Venter (Slovenia). While taking Trimetad (three times before meals), I added half a tablet (0.5 g) of Venter at night. On the second day, I stopped waking up at night from stomach pain and eating. The worries went away and life became more fun. Venter is much cheaper in price than the previously mentioned drugs.

Sources:

• https://gastritinform.ru/www.likar.info/lekarstva/Venter/
• https://gastritinform.ru/instrukciya-otzyvy.ru/520-venter-po-primeneniyu-analogi-tabletki-granuly-rastvor-yazva-zheludka-obostrenie.html
• https://gastritinform.ru/yod.ua/drug/venter/
• https://health.mail.ru/drug/venter/

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