Lespefril: prices in online pharmacies
Lespefril oral solution 100 ml 1 pc.
Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!
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Instructions for medical use
LespefrilInstructions for medical use - RU No. LS-000571
Last modified date: 05.04.2017
Compound
To prepare 1000 ml of the drug you need:
Lespedeza two-color shoots – 708 g
Ethyl alcohol 95% (ethanol) – 1210 ml
Purified water – 680 ml
Anise oil – 0.7 g
Description of the dosage form
The liquid ranges from light brown with an orange tint to reddish-brown color with a characteristic odor. Presence of sediment is allowed.
Pharmacological (immunobiological) properties
Helps increase renal filtration, reduces azotemia, increases the excretion of nitrogenous wastes in the urine, increases diuresis and the excretion of sodium ions and, to a lesser extent, potassium ions.
Increased individual sensitivity to the components of the drug, pregnancy, breastfeeding, liver disease, alcoholism, epilepsy, traumatic brain injury, brain diseases, age under 18 years.
If you have one of the listed diseases, be sure to consult your doctor before taking the drug.
Directions for use and doses
Orally, 5-15 ml (1 teaspoon - 1 tablespoon) 3-4 times a day. It is allowed to dilute the drug with water before use. The course of treatment is 3-4 weeks. A second course of treatment is possible 2-3 weeks after consultation with a doctor.
Side effects
Allergic reactions are possible. In rare cases, hyponatremia.
If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.
Interaction
Due to the ethanol content of the drug, simultaneous use of disulfiram, sedatives, non-selective monoamine oxidase inhibitors, insulin, metformin, and sulfonamide is contraindicated.
When prescribing several drugs together, it is necessary to take into account the presence of ethanol in the drug, as it can change or enhance the effect of other drugs
special instructions
If hyponatremia develops, it should be compensated by administering drugs containing sodium ions.
The drug contains at least 40% ethanol. In the maximum single dose of the drug, the ethanol content is at least 4.7 g, in the maximum daily dose - at least 18.8 g.
During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Release form
Oral solution. 100 ml in orange glass bottles or polyethylene terephthalate bottles. Each bottle along with instructions for use in a cardboard pack.
Store in a place protected from light at a temperature of 15 to 25 °C.
Keep out of the reach of children.
Lespefril - instructions for use and analogues
The drug Cystinol Acute is used in urology, has an antibacterial effect, and is used to treat inflammatory diseases of the lower urinary tract. In the form of a solution for oral administration, liquid, transparent, brown in color with a slight orange tint, with the absence of suspended particles, characterized by the specific odor of ethyl alcohol.
The medication has a pronounced anti-inflammatory, hypoazotemic and diuretic effect, and also cleanses the body of various wastes and toxins. The product increases daily diuresis and promotes sodium excretion.
The instructions for Lespenefril indicate that the drug must be stored in a dark, cool place out of the reach of children. Shelf life – 5 years.
The medicine is made on the basis of plant materials and is used as a symptomatic medicine against chronic kidney failure (CRF). The main component of the solution is an extract of lespedeza bicolor shoots. The composition also contains ethyl alcohol (solvent) and anise oil.
The kidneys are the main paired organ of the urinary system, which plays the role of a so-called filter. Its task is to maintain the acid-base balance and remove the final breakdown products of nitrogenous and toxic compounds.
Lespefril is indicated orally, up to four times a day, before meals. Variations in a single dose are allowed from 1 teaspoon to 1 tbsp. spoons (5-15 ml) - depends on the severity of the symptoms of the disease.
By its nature, the shrub plant is a corrector of protein, carbohydrate, mineral and lipid metabolism. In addition, it is an important component that takes part in cleansing the body of toxic products and compounds.
Analogues of Lespenefril
Synonyms for the drug Lespenefril are available both in the form of syrup and tablets.
There are three absolute structural analogues of the drug:
These medications have the same indications and contraindications for use as the original. The dosage of the tincture is unchanged. Herbal raw materials are brewed at the rate of two tablespoons per two glasses of boiling water. Leave in a water bath for a quarter of an hour, cool, strain. Drink 50 ml three times a day. It is better to store the broth in a thermos.
Preparations with similar effects, also based on herbs and plants, include:
| Name | Main herbal ingredients | Release form | Indications | Manufacturer | Price |
| Canephron N | Centaury (herb), rosemary (roots), lovage (roots) | Dragee, water-alcohol solution | Inflammation of the bladder (cystitis), pyelonephritis (acute and chronic), nephritis of various etiologies | Bionorica SE, Germany | 430 rub. |
| Cyston | Dicarp (flowers), strawflower (seeds), saxifrage (stems), membranous sap (roots), aerial parts of the bractal onosmata, ash vernonium, heartleaf madder (stems), purified mineral resin | Tablet form | Pyelonephritis, cystitis, the presence of stones and sand in the kidneys | Himalaya (India) | 390 rub. |
These drugs cannot replace Lespenefril with 100% effectiveness and have a number of contraindications. Therefore, when choosing a medicine, preference should be given to natural analogues with an identical composition.
Analogs
Due to the fact that Lespefril contains a herbal component, the drug may not be suitable for the treatment of patients with individual intolerance or hypersensitivity. For this reason, the selection of an effective analogue would be justified.
Baytach
A tablet analogue of Lesperfil containing extracts of Scutellaria baicalensis, adenosmatis blue herb and desmodia styraxolifolia herb. It is used in urological practice for the treatment of renal failure accompanied by urolithiasis. Contraindicated for use in pediatrics, as well as during pregnancy, colitis, hypersensitivity, peptic ulcer, lactation and gastroesophageal reflux disease.
Drops for oral use. Herbion contains extracts of steelweed root, horsetail herb, bearberry leaves, birch leaves and parsley root. It is used for acute and chronic inflammatory pathologies of the kidneys and/or bladder. Gerbion is strictly contraindicated during pregnancy, lactation, hypersensitivity, liver pathologies, epilepsy, ulcers of the gastrointestinal tract, brain disorders, edema, hypersensitivity and in pediatrics.
Rendesmol
An analogue of Lespefril in the form of film-coated tablets. Contains Desmodium styraxolifolia herb extract. Rendesmol is used in urological practice for the treatment of urolithiasis and cholelithiasis, as well as cholecystitis and pyelonephritis. It is prohibited to resort to the use of this analogue in case of increased sensitivity of the patient to the action of the active or auxiliary components, peptic ulcer of the gastrointestinal tract, pregnancy, breastfeeding and in pediatric practice (children and adolescents under 18 years of age).
Contraindications
A drug
used for symptomatic therapy as a hypoazotemic and diuretic agent for chronic renal failure.
Contraindications to the use of the drug
are: hypersensitivity to the drug, pregnancy, breastfeeding. Due to the presence of alcohol, the drug should not be prescribed to patients receiving treatment with drugs that depress the central nervous system, insulin, hypoglycemic agents (metformin sulfonamides), drugs for the treatment of alcoholism.
The drug Lespefril is indicated for impaired renal function. Before use, it is recommended to consult a doctor to identify contraindications and restrictions on the use of the product.
for adults
Lespefril is prescribed to adult patients for the symptomatic treatment of chronic renal failure.
for children
The use of the drug Lespefril in children and adolescents under 18 years of age is strictly contraindicated.
During pregnancy and breastfeeding, it is strictly prohibited to use the drug Lespefril.
The drug Lespefril is contraindicated for use in the following conditions:
- epilepsy;
- children under 18 years of age;
- alcoholism;
- period of breastfeeding;
- brain pathologies;
- individual intolerance or hypersensitivity to the active or additional components of the drug;
- liver pathologies;
- pregnancy;
- traumatic brain injuries.
Description and instructions for the drug Lespeflan
Lespeflan is a domestically produced medical product. Used in urology. Increases renal filtration, removes nitrogenous wastes with urine, increases diuresis.
Available in the form of an aqueous-alcoholic solution of purified extract. It is made from the stems and leaves of Lespedeza. This plant is unique in its kind; it stabilizes water-salt metabolism, cleanses the body of metabolic products, and has a toxin-removing and diuretic effect.
This drug also contains essential anise oil. It has an active anti-inflammatory effect on the urinary tract.
Application of Lespeflan:
- inflammation of the kidneys in chronic renal failure;
- pyelonephritis;
- glomerulonephritis.
Lespeflan contains ethyl alcohol.
Contraindications
It is not recommended to use:
- in case of allergic reactions and hypersensitivity to the components of the drug;
- for diseases of the brain;
- traumatic brain injuries.
Prohibited in childhood and pregnancy.
Side effects
The side effects of this medicine are mainly associated with the high content of ethyl alcohol. They may manifest themselves in the form of arrhythmia, tachycardia, slowed psychomotor reactions, and drowsiness.
Lespeflan flushes sodium from the body, so mild hyponatremia may occur.
Allergic reactions almost never occur; they can only occur in people who are prone to allergies.
If the dose is exceeded, more acute poisoning with Lespeflan may occur, which occurs in the form of alcohol intoxication.
Composition and pharmacological action
The drug Lespeflan is a hypoazotemic drug of plant origin. With regular use, the medicine helps reduce the concentration of nitrogen metabolism in the blood, increases the clearance of urea, uric acid and creatinine.
The medication has a pronounced anti-inflammatory, hypoazotemic and diuretic effect, and also cleanses the body of various wastes and toxins. The product increases daily diuresis and promotes sodium excretion.
Unlike most similar products, Lespeflan contains exclusively natural components and ingredients, due to which the risk of side effects and complications while taking it is minimized. To prepare 1000 ml. solution, required:
- 95% ethyl alcohol – 1210 ml;
- bicolor lespedeza shoots – 708 gr.;
- anise extract – 0.7 ml;
- distilled water – 680 ml.
Side effects
When using the drug Lespefril, the following side effects are possible:
In rare cases:
- allergic reactions (moderate, relieved with antihistamines (Zyrtec, Erius, Claritin, Suprastin, etc.);
- development of hyponatremia due to increased excretion of sodium in the urine;
- dizziness;
- heartbeat;
- drowsiness;
- weakness.
These side effects are mainly caused by a deficiency of sodium in the body. It is recommended to directly increase the consumption of table salt. All other side effects are caused by the presence of ethyl alcohol in the solution.
Alcohol can cause:
- drowsiness;
- dizziness;
- blurred consciousness;
- apathy.
Similar drugs:
- Celandine grass (Chelidonii majoris herba) Vegetable raw materials
- Tamsulid Capsule
- Diacarb Oral tablets
- Epletor Oral tablets
- Britomar Oral tablets
- Verospiron Oral tablets
- Hypothiazid Oral tablets
- Lespenephryl Oral solution
- Lipril (Liprilum) Oral tablets
- Horsetail (Equisetum arvense) Vegetable raw materials
** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use Lespefril, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Lespefril is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!
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Therapeutic effects and action of Lespefril
The therapeutic action and medicinal effects of Lespefril are due to the chemical compounds included in the Lespedeza tincture, such as catechins, flavones, isoterpenoids and a number of others.
Catechins are similar in their type of action to vitamin P. That is, they are vascular protectors, strengthening the capillary wall and preventing the release of fluid into the tissues with the development of edema.
Lespefril also has a powerful diuretic effect, which is often simply called a diuretic. Increased urination occurs due to the activation of filtration processes in the renal tubules. Moreover, Lespefril has quite rare and unique properties - it is a potassium-sparing diuretic. This means that under its influence only sodium is washed out of the blood, while potassium remains. Saving potassium prevents heart problems, and sodium concentration can be easily replenished with regular table salt. A widely known potassium-sparing diuretic from industrial pharmaceutical production is Veroshpiron (Spironolactone).
The third most important therapeutic effect of Lespefril is to cleanse the blood of nitrogenous compounds, which are very toxic. These compounds include the following substances: 1.
Urea.
2.
Creatinine.
3.
Uric acid.
These nitrogenous compounds are constantly produced in the human body, and are the end products of the metabolism of proteins and purine bases (components of DNA), that is, essentially waste products that should be quickly eliminated. If kidney function is impaired, these nitrogenous substances remain in the circulating blood and poison the human body. And Lespefril effectively removes these nitrogenous components from the blood, the presence of which is due to insufficient functional activity of the kidneys. By removing endogenous toxic substances from the blood, Lespefril improves a person’s overall well-being.
In addition, the drug Lespefril has a mild anti-inflammatory effect, reducing the severity of this pathological process localized in the organs of the urinary system (kidneys, bladder, ureters, urethra).
Release forms and composition
Lespefril is available in the form of a solution in 100 ml bottles or dark glass jars. The solution is liquid, transparent, does not contain suspended particles and is brown in color with a slight orange tint. Lespefril has a specific odor of ethyl alcohol.
Lespefril contains the following components: 1.
Alcohol tincture of two-color Lespedeza – 15 ml.
2.
Anise essence – 0.25 ml.
3.
Ethyl alcohol at a concentration of 70% – 84.75 ml.
The active component of the drug Lespefril is a tincture of a medicinal plant - Lespedeza bicolor
. To achieve optimal dissolution and uniform distribution throughout the fraction of all chemical substances that Lespedeza tincture contains, anise in the form of an essence was added to the solution. The fatty essence is necessary to dissolve certain classes of chemicals present in Lespedeza, which have positive effects on the human body. Also, these fat-soluble substances (for example, coumarins, flavonoids, etc.) from Lespedeza tincture are better absorbed into the bloodstream, being evenly dispersed in the anise essence.
The alcohol in Lespefril plays the role of a solvent with polar properties. That is, it is possible to successfully and uniformly disperse both the fat-soluble substances in the anise essence and the water-soluble components of the Lespedeza tincture. It is the properties of alcohol, as a polar solvent, that make it possible to collect in one solution the necessary active substances from Lespedeza tincture with a fundamentally different chemical structure - water-soluble and fat-soluble.
Dosage and method of administration
Lespenefril is indicated orally, preferably before meals.
When taken orally, depending on the clearance of creatinine, the tincture is prescribed per kg of body weight, 0.5-1 ml, the loading daily dose is considered to be 2-3 teaspoons, the average daily dose is considered to be 1-2 teaspoons with a dosage frequency of two to three times per day. day.
For long-term treatment, the daily maintenance dose is up to 1 teaspoon per day for two weeks every month.
For parenteral administration, 1 mg of pure extract is used per kilogram of weight; it is preferable to administer the drug intravenously or by perfusion.
The daily average dose is 4 bottles, the highest is considered to be 10 bottles per day.
Lespefril - instructions for use and reviews
Orally, before meals - 1-2 teaspoons 2-3 times a day. Before use, dilute the drug with a small amount of water. The course of treatment is 3–4 weeks.
I have been suffering from mild kidney failure for the past two years. The doctor prescribed Lespenefril solution to support the functioning of the urinary system. The medicine works great! I like that it has a natural composition, is not addictive, and there are practically no side effects. In the first days I felt a little nauseous, but now I don’t feel that way.
Dosage 1 tablet 0.03 grams. The plant base of flaronin is excellent for the treatment of prostatitis, which usually requires long-term treatment.
The medicinal collection Nephrofit is used as a prevention and complex treatment of inflammatory diseases of the kidneys and urinary tract, which are accompanied by a decrease in urinary and nitrogen excretion function, urolithiasis, and edema.
Contraindications for use
Despite its relatively safe composition, the medication has some contraindications, which are important to consider when prescribing treatment. Absolute restrictions include:
- children's age (up to 18 years);
- alcohol dependence (the drug is incompatible with alcohol due to an increase in the level of toxicity in the body and danger to the liver);
The drug should not be taken together with disulfiram, non-selective monoamine oxidase inhibitors. Complex therapy with the use of sulfonamide and metformin is not recommended. The effect of sedative medications can be unpredictable, so treatment using them is also excluded
Also, when used together, it is important to take into account the presence of ethyl alcohol in the composition, which can increase toxicity and side effects.
It is not recommended to use Lespefril in cases of severe hyponatremia. But the condition can be compensated for with sodium medications.
During the treatment period, care must be taken when driving vehicles and machinery. It is recommended to avoid activities that require increased concentration and quick reactions.
Lespefril: indications for use
Therapy for chronic lesions of body systems comes down to prolonging periods of remission, reducing the stages of exacerbation and relieving symptoms. In the treatment of chronic renal failure, Lespefril is often used, which helps slow down destruction and reduce inflammation.
Description and characteristics
The medicine is made on the basis of plant materials and is used as a symptomatic medicine against chronic kidney failure (CRF). The main component of the solution is an extract of lespedeza bicolor shoots. The composition also contains ethyl alcohol (solvent) and anise oil.
The drug has a diuretic effect, but does not flush potassium and magnesium from the body.
Lespedeza is a natural regulator of metabolic processes in the body, affecting the functioning of all systems. The medicine is included in complex therapy and is used separately.
When treating the genitourinary system and kidneys, the solution alleviates the course of the disease and shortens the period of exacerbation of chronic renal failure. As part of complex therapy, Lespefril has the following effects:
- restoration of metabolism;
- maintaining and restoring immunity;
- regulation of water-salt metabolism in the body;
- excretion of nitrogenous wastes through urine;
- increasing the rate of sodium excretion.
The medication is available in the form of a solution for internal use. The standard packaging volume is 100 milliliters. The average cost of a bottle is 150-200 milliliters, dispensed without a doctor's prescription. Due to the characteristics of the composition and mechanism of action, information on pharmacokinetics and pharmacodynamics is insufficient.
Indications and features of use
The main indication for use of the drug is chronic renal failure. With this disease, the drug helps relieve inflammation and improve fluid excretion. Lespefril also helps as part of complex therapy for the following lesions and conditions of the body:
- pyelonephritis;
- urolithiasis disease;
- kidney stone disease;
- glomerulonephritis.
The main purpose of the medicine is auxiliary. The medication improves the general condition of patients, helps improve well-being, and eliminates unwanted symptoms. Lespefril is effective against kidney disease in which renal failure is a symptom or complication.
Before use, the medicine must be diluted in a small amount of clean water.
The drug is used up to four times a day. The size of one dosage for an adult is from 5 to 15 milliliters (from a teaspoon to a tablespoon), depending on the indications, the severity of the lesion and the individual characteristics of the patient. The duration of the therapeutic course is also determined individually.
Typically it lasts from three to four weeks. The course can be repeated with a break of two to three weeks. Meal regimen is not important since absorption data are not available.
Negative effects
Lespefril is a relatively safe herbal medicine that rarely causes side effects. In some cases, allergic reactions may occur in the form of urticaria, skin rash and redness, itching, and swelling.
The drug does not wash out potassium and magnesium, but with systematic use there is a risk of hyponatremia. In such situations, medications, multivitamins and foods containing sodium help compensate for the loss of microelements.
In case of overdose, the likelihood of allergies and hyponatremia increases.
Taking Lespefril together with alcohol can enhance the effect of the latter. Ethyl alcohol is also contained in the solution.
The component can also enhance the effect of other medications, which is important to consider when using other medications, including sedatives.
If it is necessary to include other medications in a complex treatment, it is important to consult a doctor to prevent the development of undesirable effects.
Contraindications for use
Despite its relatively safe composition, the medication has some contraindications, which are important to consider when prescribing treatment. Absolute restrictions include:
- children's age (up to 18 years);
- alcohol dependence (the drug is incompatible with alcohol due to an increase in the level of toxicity in the body and danger to the liver);
- epilepsy;
- pregnancy, breastfeeding;
- traumatic brain injuries;
- liver damage, dysfunction of the hepatic system against the background of progression of various pathologies of the organ;
- hypersensitivity to the main component and other substances in the composition of the drug;
- various types of brain diseases.
The drug should not be taken together with disulfiram, non-selective monoamine oxidase inhibitors. Complex therapy with the use of sulfonamide and metformin is not recommended.
The effects of sedative medications can be unpredictable, so treatment using them is also excluded.
Also, when used together, it is important to take into account the presence of ethyl alcohol in the composition, which can increase toxicity and side effects.
Particular caution should be exercised in patients suffering from insulin-dependent diabetes mellitus, since Lespefril is not compatible with insulin medications.
It is not recommended to use Lespefril in cases of severe hyponatremia. But the condition can be compensated for with sodium medications.
During the treatment period, care must be taken when driving vehicles and machinery. It is recommended to avoid activities that require increased concentration and quick reactions.
Storage and sales conditions
The drug is available exclusively in liquid form. Manufacturer: VIFITECH (Russia). When purchasing, you do not need a doctor's prescription, but it is not recommended to purchase the medication without a prescription due to the list of contraindications.
The medicine must be stored in a dark place, protected from children and animals, at a temperature of 15 to 25 degrees. The shelf life of unopened packaging is 3 years. After opening and consumption, the shelf life is reduced to a month.
Analogues and substitutes of the drug
A complex of mild diuretic, anti-inflammatory and analgesic effects can be provided by a lot of herbal and chemical-based medicines. Substitutes with a similar composition and mechanism of action are produced in liquid form.
| A drug | Active substance | Manufacturer | Cost (rubles) |
| Renel (tablets) | Aluminum Oxide + Nitric Acid + Lead Acetate + Barberry + Chondodendron Felt + Spanish Fly + Hahnemann's Caustic Soda + Saw Palmetto | Biologische Heilmittel Heel GmbH (Germany) | 350-400 |
| Canephron N (alcohol solution, dragee) | Centaury herb, lovage roots, rosemary leaves | Bionorica SE (Germany) | 450-500 |
| Bioprost (rectal suppositories) | Pumpkin seed oil + Thymol | CJSC IntelPharm (Russia) | 550-580 |
| Afala (tablets) | Antibodies to prostate-specific antigen | NPF Materia Medica Holding LLC (Russia) | 400-420 |
| Tentex Forte (tablets) | Combination of powdered herbal extracts | HIMALAYA DRUG (India) | 580-600 |
| Speman (tablets) | Combination of herbal extracts | HIMALAYA DRUG (India) | 1200-1300 |
Analogs are selected if Lespefril is insufficiently effective or if there is increased sensitivity to the manufacturing components.
Differences between Lespefril and Lespeflan
Lespeflan is a herbal medicine in the form of a solution. Sold through pharmacy chains at an average cost of 200-240 rubles without a doctor’s prescription.
Manufacturers of the drug: DALKHIMFARM (Russia), PHARMACENTR VILAR (Russia). The main component of the medicine is also a liquid extract of lespedeza bicolor shoots.
The composition contains ethyl alcohol and anise oil.
Differences from Lespefril can be studied according to the instructions. The manufacturer of Lespeflan indicates that the list of side effects may include heartbeat disturbances, tachycardia, and slowed psychomotor reactions.
The solution rarely causes allergic reactions. The difference is also in price. The average cost of Lespeflan is 30-40 rubles higher in Russian pharmacy chains.
The dosages of the medication are the same; the instructions recommend taking the medication before meals once a day.
What is better than Lespefril and Lespenefril?
Lespenefril and Lesprefril differ insignificantly in composition. Lespenefril is based on lespedeza capitate powder, ethyl alcohol and anise essence (Lesprefril contains anise oil). In terms of use, Lespenefril is better because it is sold in a solution for internal use and injection.
This allows you to expand the range of applications, but increase the list of contraindications and side effects. The average cost of a package of medicine is 120-130 rubles. Manufacturer: UCB HealthCare (France).
Which is better: Lespefril or Canephron
Canephron N also contains plant components: extracts of rosemary leaves, centaury herb, and lovage. The medication is available in the form of a solution and tablets, which makes the administration process easier. The list of indications for use includes chronic renal failure and various non-infectious lesions of the urinary tract.
The differences between Canephron N and Lespefril also include a wider range of contraindications and side effects. But the plant base also makes the medication relatively safe for regular use.
In some cases, it may be taken during pregnancy and breastfeeding. The medicine is used in pediatrics (Lespefril is prohibited for use by patients under 18 years of age). The average cost of a package of Canephron N is 400-450 rubles.
The manufacturer of the medicine is Bionorica SE, Germany.
Features of the drug
Lespefril is a medicine in the form of a solution of plant origin, which is actively used in the treatment and prevention of exacerbations of chronic renal failure. When used systematically, the drug relieves pain, inflammation and other negative symptoms of the disease.
Lespefril also regulates metabolic processes in the body's systems and causes a minimum of side effects. The advantage of the medicine is also a relatively small list of contraindications. If necessary, it is possible to select analogues of the medication without a doctor’s prescription.
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Lespefril or Lespenefril?
The Russian drug Lespefril is an analogue of the French drug Lespenefril. The drugs differ from each other in that the Russian one contains Lespedeza bicolor, and the French Lespenefril contains Lespedeza capitata. That is, the active components are different types of the same medicinal plant.
By creating an analogue of Lespenefril, domestic scientists pursued the goal of establishing the production of an effective but inexpensive drug. Therefore, the indications and contraindications for use of both drugs are exactly the same. However, the effectiveness of Lespenefril exceeds that of the domestic Lespefril. Therefore, the dosages in which Lespenefril is taken are somewhat lower. This is explained by a better degree of purification and standardization of ready-made tinctures of Lespedeza capitata, on the basis of which a solution taken orally is prepared.
French pharmaceutical corporations also produce Lespenefril in ampoules, intended for administration in the form of intramuscular or intravenous injections. The drug can be injected into people who cannot drink alcohol, including pregnant women and children.
Bioflavonoids
In the body of the lespedeza itself, bioflavonoids act as signaling molecules between different plant cells, and also determine the protection of the photosynthetic apparatus from damage by ultraviolet radiation and from the invasion of pathogenic microorganisms. However, in the human body they are much more important for the kidneys.
Thus, the effectiveness of the drug "Lespenefril", the instructions for use of which do not include a specific pharmacological mechanism of action, is explained by the direct influence of the biologically active substances included in its composition. The fact is that bioflavonoids strengthen capillary walls, which are damaged in the kidneys in most diseases. The latter include glomerulonephritis, pyelonephritis, interstitial nephritis, arterial hypertension, atherosclerosis, diabetes mellitus and many others.
Drugs
These include ornithine (Ornitsetil and Hepa-Merz preparations), lactulose (Duphalac syrup), amino acids for parenteral nutrition (Hepasol A solution) and herbal lespedeza (Lespeflan and Lespenefril medicines). The instructions for use of these medicines inform customers about their pronounced detoxifying effect, which consists precisely in the neutralization of ammonia, increased renal filtration and diuresis.
Thus, these drugs have a beneficial effect on the kidneys and help restore their functions. The price of Lespenefril varies in different regions of the country, but on average it is about 90-100 rubles per bottle. By the way, it is made of dark glass so that the sun's rays do not affect the quality of the tincture and do not reduce its shelf life. And the price of Lespenefril in the form of an oral solution is slightly lower than for the tincture. However, both bottles contain only 120 ml of the drug, which is usually not enough for the entire course of treatment.
Danger of overdose
If a person independently increases the dosage of the drug and adheres to this treatment regimen for several days, signs of an overdose may soon appear.
Experts assure that the manifestation of symptoms is similar to ordinary alcohol intoxication; most patients complain of disorders:
- the occurrence of frequent dizziness;
- severe headache;
- nausea and vomiting;
- hand tremors;
- increased sweating.
If such symptoms occur, you must immediately call a team of doctors who will help relieve the symptoms.
