What kind of drug
The drug Phlebodia 600 is a popular remedy used in phlebology. The medication is used to eliminate pathological processes of the venous system, in particular varicose veins and chronic venous insufficiency.
The drug contains a complex of active ingredients, but the main role belongs to diosmin, a common angioprotector with a venotonic effect.
The manufacturer and supplier of the medicine is the French pharmaceutical company. Due to the fact that the number of tablets in the package, the price of the drug also varies. On average, you will have to pay about 770 rubles per package. The dosage is unchanged.
Venarus or Phlebodia – which is better for varicose veins?
Venarus differs from the drug Phlebodia in several respects:
- Composition – Venarus contains two active components. It also contains diosmin, but in a smaller dosage.
- Dosage regimen - according to the instructions, Venarus must be taken twice a day.
- Manufacturer . Phlebodia is a drug from a French company, Venarus is from a Russian company.
- Price - 30 tablets of Venarus cost about 550 rubles, the same amount of Phlebodia costs about 1000 rubles.
Each patient independently decides which of these criteria is more important for him, and then decides on the choice of drug. Usually people hesitate between financial affordability and French quality.
A worthy analogue of the drug Phlebodia is Detralex, which is also produced in France and is of high quality. The difference lies in the composition - Detralex, like Venarus, contains two active components. Which is better, Detralex or Phlebodia for varicose veins, read in this article.
Compound
The main and active substance present in the medication is diosmin in the form of granules. They contain 600 g of dry anhydrous substance that has undergone chemical purification. In addition to the main substances, the composition contains the following auxiliary elements:
- MCC;
- talc;
- colloidal silicon dioxide;
- stearic acid;
- dyes - titanium, iron oxide, propylene glycol;
- beeswax;
- ethanol at a concentration of 95%;
- opaglos 6000 - palm wax.
The tablets are film-coated, the composition of which is microcellulose, polyethylene glycol stearate and hypromellose. Externally, they are round, predominantly pink in color, with an interesting “mantle” on the cut, inside of which there are brown kernels.
Release form and composition of the drug
The drug is available in round, convex tablets with a pink film coating. The tablets are packaged in blisters of 15 pcs. and are placed in cardboard packaging along with instructions for use.
A pack may contain 1 or 2 blisters for bandaging for varicose veins of pregnancy, that is, 15 or 30 tablets.
The active ingredient of Phlebodia 600 is “Diosmin” 600 mg, auxiliary products include a device for pressotherapy of varicose veins:
- microcrystalline cellulose 910 mg;
- stearic acid – 50.05 mg;
- colloidal silicon dioxide – 3.5 mg;
- talc – 10.24 mg.
- shellac 150 mcg;
- beeswax 75 mcg;
- carnauba wax 75 mcg;
- red oxide 20 mcg;
- black oxide 130 mcg;
- crimson dye 401 mcg;
- titanium dioxide, vein bandaging for varicose veins – 4,026 mg;
- hypromellose, propylene glycol 458 mcg;
- macrogol stearate – 1.967 mg;
- microcrystalline cellulose – 7.866 mg;
- hypromellose – 9.832 mg.
The drug has a number of active substance analogues, which differ in the content of excipients.
Properties
The medicine has a number of positive properties. In addition to venotonic properties, it has anti-inflammatory, angioprotective and moderate phlebotonic effects.
It is important that the drug affects the lymphatic system, accelerating fluid drainage, which prevents the formation of edema.
Necessary properties of the drug to eliminate pathologies of venous vessels:
- Elimination of vascular distensibility.
- Maintaining the vascular wall in tone.
- Restoring the elasticity of the endothelium and muscle layer of the vein.
- Preventing damage to small vessels.
- Preventing the formation of venous patterns on the extremities.
- Accelerates blood circulation and gets rid of congestion.
Taking pills during pregnancy
During clinical trials, no harmful effects of the drug on the fetus were detected. However, it is recommended that pregnant women buy the medicine only after consulting a gynecologist.
In this case, the benefit of treatment for the mother usually outweighs the possible risk for the child. Pregnancy is one of the triggers for the development of varicose veins, hemorrhoids and other vascular problems . Phlebodia also has a positive effect on blood circulation in the pelvic organs, prevents stagnation and prevents swelling, which is externally invisible.
Destruction of the structure of blood vessels is better to prevent than to treat. Combating venous insufficiency and restoring the structure of the veins is much more difficult than following preventive measures. Quite often it is not possible to achieve a positive result with conservative treatment, then the patient is recommended to undergo surgical intervention. You can read in detail about laser removal of varicose veins here.
pharmachologic effect
The drug belongs to the pharmaceutical group of anti-varicose veins in a chronic form.
Pharmacodynamics and pharmacokinetics
The active substance of the drug has a wide range of positive qualities necessary for the normal functioning of venous blood vessels.
Diosmin prevents blood stagnation in the vein, reduces its permeability and restores elasticity. Due to these qualities and reduced permeability, the lymphatic drainage system is restored and vasoconstrictive processes are launched.
The active component Phlebodia 600 acts on the adhesion of leukocytes, which prevents the development of inflammation in the area of the affected vessel and adjacent tissues. In combination, the drug accelerates blood supply processes without damaging the endothelial layer.
Once in the gastrointestinal tract, it undergoes rapid absorption and maximum distribution in the blood serum. After approximately 120 minutes, the active component is detected in the bloodstream and reaches its maximum concentration after no less than 5 hours.
Composition and properties
Phlebodia for veins, unlike many other medications for varicose veins, contains only one active ingredient. It is diosmin, which is a semi-synthetic substance. In nature, it is found in some plants, and is synthesized artificially for medicines.
Diosmin belongs to the group of venotonics - agents that exhibit vascular strengthening properties and increase the activity of veins. The drug is able to restore the structure of the venous wall, reduce its permeability, improve metabolic processes, and enhance lymphatic drainage.
When taken orally, the drug is quickly absorbed from the gastrointestinal tract into the blood and begins to act. It is distributed throughout all tissues of the body, found in the kidneys, liver, and lungs. The maximum tropism is observed in relation to the vessels of the bloodstream, so Phlebodia has found its application in phlebology.
Clinical results appear within a few days of treatment.
Indications
Phlebodia 600 tablets are taken orally. The grounds for admission are:
- Varicose veins of the lower extremities of acute and chronic course, as well as varying degrees of the pathological process.
- Prevention and complex treatment of insufficient drainage of lymphatic fluid.
- CVI.
- Hemorrhoids in the initial stage.
- Hemorrhoidal crisis.
The primary signs of varicose veins of the lower extremities are the appearance of swelling, pain and numbness.
Indications and contraindications
The product can be used for all vascular pathologies, venous insufficiency, as well as diseases that are accompanied by similar problems. Indications for use of Phlebodia:
- lymphovenous insufficiency of the lower extremities, including varicose veins;
- microcirculation disorders, trophic disorders;
- haemorrhoids.
Depending on the etiology and stage of the disease, Phlebodia can be used independently or as part of complex therapy.
The drug has a high safety profile, and has only a positive effect on blood vessels, so it has virtually no contraindications. Tablets are not recommended for use only if:
- hypersensitivity to the main or auxiliary component;
- the patient's age is under 18 years;
- pregnancy and lactation.
The last point is a relative contraindication. Some doctors prescribe Phlebodia to pregnant women, since during this period the load on the blood vessels increases significantly. You can learn more about varicose veins of the rectum, which is also common in pregnant women, here.
Side effects
Adverse reactions are rare. Most often, patients during therapy with oral phlebotonics are concerned about:
- headache;
- allergies - general and local;
- dyspeptic disorders - flatulence, heaviness in the stomach, dyspepsia;
- bad breath and oral discomfort;
- itching of the skin in “tender areas”, for example, the inner bend of the elbow.
In most cases, the medicine is well tolerated by patients, without the development of unwanted side reactions.
Method and dosage
The tablets are taken orally, without chewing and with an average volume of water. The treatment regimen is determined individually and depends on 3 factors:
- The degree of the pathological process.
- Main diagnosis.
- Presence of associated complications.
The maximum daily dosage is 1800 mg or 3 tablets of medication.
Reception does not depend on the time of day, food intake or period of wakefulness. At the onset of venous diseases, the medicine is prescribed once a day, but in the absence of severe pain. Subsequently, the amount of drugs increases to 2-3 tablets.
The course of basic treatment is 2-3 months; if complications occur or there are trophic changes in the skin, it increases to 6 months.
For preventive purposes, the dose is taken once a day. For the effectiveness of treatment, it is recommended to adhere to the treatment regimen established by the phlebologist.
For the treatment of hemorrhoidal crisis, Phlebodia 600 is used as part of a comprehensive treatment of the disease.
Phlebodia and alcohol
The official instructions do not prohibit the simultaneous use of Phlebodia 600 and alcohol.
However, alcohol-containing drinks and medications themselves negatively affect the condition of blood vessels, reducing their elasticity and causing expansion and then narrowing.
There is no direct interaction between diosmin and alcohol, but the therapeutic effect is weakened when taken simultaneously. Patients are not recommended to drink alcohol during the entire course of venotonic therapy.
The first signs of varicose veins are spider veins. It is during this period that, with proper treatment, varicose veins can be effectively eliminated. For those who do not want to worry and look for symptoms of the disease, doctors recommend that they engage in prevention, which is based on drugs from the group of venotonics. Read also what red spots on the lower legs indicate in this article
During pregnancy
One of the contraindications to the use of the medicine is the gestation period, as well as the practice of breastfeeding. This is due to the lack of data on the effect of diosmin on the fetus.
However, diosmin is not a teratogenic drug, and therefore does not affect the course and outcome of pregnancy.
Doctors do not recommend taking Phlebodia 600 in the first trimester of gestation, or doing so under close, round-the-clock supervision by medical personnel.
Often, pregnant women take medication to eliminate swelling due to lymphovenous insufficiency in the chronic stage. In this case, the regimen is as follows: 1 tablet once a day, regardless of meals. Therapy is stopped 3 weeks before the expected date of birth.
In pediatrics, diosmin is not used to treat young patients under eighteen years of age.
Summarizing
You have learned about a new effective medicine “Phlebodia 600”. Instructions for use, price, reviews, as well as the composition of the drug are presented to your attention. You also learned about drug analogues. Remember that independent replacement of the prescribed medication is unacceptable. This can cause various complications. You should consult a doctor with this question. Particular care must be taken when treating during pregnancy. If the medication is used for a long time, it is necessary to monitor the condition of the blood. Healthy veins and blood vessels to you!
