Cocarnit. instructions for use in ampoules, tablets, intramuscular injections, compatibility, contraindications. price, analogues, reviews

Indications for use

Indicated for diabetic neuropathy (pins and needles, neurogenic pain), coronary heart disease, neurocirculatory dystonia, during the period after recovery from stroke and heart attack, with transient ischemic attacks, fainting.
The instructions for use indicate sciatica and radiculitis. Contraindicated in case of hypersensitivity to the drug, increased blood clotting, pregnancy, lactation, age under 18 years, acute heart failure, thromboembolism, hemorrhagic stroke, obstructive bronchitis, bronchial asthma, liver cirrhosis, hepatitis, exacerbation of gastric or duodenal ulcer.

The drug should not be used for uncontrolled hypertension, hypotension, prolongation of the QT interval, cardiogenic shock, or bradyarrhythmias.

The drug should not be used for uncontrolled hypertension.

Like most pharmaceutical medications, the Kokarnit complex product has a certain list of restrictions for use. The instructions supplied by the manufacturer indicate:

• individual hypersensitivity to the components of the medication;
• severe arterial hypertension;
• tendency to hypotension;
• psoriasis;
• diagnosed conduction disorders of heart rhythm impulses;
• decompensated heart failure;
• acute recovery period of myocardial infarction.

Particular caution is recommended when carrying out pharmacotherapy with the drug in people who have a history of severe gastritis, gastrointestinal ulcers, and liver diseases of various etiologies.

Restrictions on the use of lidocaine must be taken into account - cardiovascular pathologies, myasthenia gravis, porphyria, renal disorders.

Cocarnit injections are prescribed for use in the presence of any of the following diseases:

• Nervous pathologies of an inflammatory nature.
• Muscle paralysis.
• Muscle pain.
• Painful symptoms, manifested due to compression of blood vessels.
• Acute pain in the lower back.
• Ischemic heart diseases.
• Inflammatory processes developing in the heart muscle.

If you have one of the above diseases, you can resort to using the drug Cocarnit, but only after prescribing a specialist or consulting with him. You can give a Cocarnit injection at home if you have a sufficient level of knowledge and practice in carrying out the procedure.

Doctors prescribe the drug Cocarnit in the following cases:

• inflammation in the heart muscle;
• paralysis or muscle pain;
• nervous inflammatory pathologies;
• ischemic disease;

• radiculitis;
• lumbago;
• neuritis and neuropathies;
• diabetic polyneuropathy.

It is prohibited to give Cocarnit injections without indications for use. Symptomatic treatment is prescribed by your attending physician; injections are not given without his recommendation. They are used exclusively intramuscularly: first of all, Cocarnit injections help against pain and inflammation in muscle tissue, so they are often prescribed for muscle pain.

No matter how painful it may be for you, if there are contraindications, maintenance therapy with Cocarnit is not possible. All your concomitant diseases are taken into account by the doctor. If there are contraindications, a remedy with a similar effect will be selected.

Indications for use of the drug

are: neuritis, neuropathies (diabetes mellitus, pernicious anemia, etc.); neuralgia of various origins; myalgia, sciatica; lumbago, radiculitis; bursitis, tendonitis; coronary heart disease, myocarditis, myocardiopathy.

Contraindications to the use of the drug

are: hypersensitivity to any component of the drug; acute period of myocardial infarction; hypersensitivity, hypercoagulation (including in acute thrombosis), erythremia, erythrocytosis, severe forms of arterial hypertension, arterial hypotension, acute myocardial infarction, inflammatory lung diseases.

Injections

• October 14, 2018
• Other drugs
• Alexa Loktionova

In the modern world, problems with the peripheral nervous system and metabolism are far from uncommon. Even many young people have diseases such as neuralgia, neuritis or myalgia, which are subject to mandatory treatment. Cocarnit injections were developed specifically for this purpose.

Indications for the use of this drug are directly related to diseases of the peripheral nervous system. However, this drug is not cheap at all, which makes you wonder: is it worth buying at all? To find out the answer to this difficult question, you need to get to know the drug in more detail and find out opinions about it from other people from the available reviews.

Release form

Lyophilisate for preparing a pinkish solution, 3 ampoules of 3 ml each in a cell package. 1 ampoule contains:

1. Trifosadenine 10 mg.
2. Nicotinamide – 20 mg.
3. Cyanocobalamin – 0.5 mg.
4. Cocarboxylase – 50 mg.

Excipients: glycine 105.8 mg, preservatives (methyl parahydroxybenzoate - 0.6 mg, propyl parahydroxybenzoate - 0.15 mg). Solvent: lidocaine hydrochloride – 10 mg, water for injection – 2 ml.

Components: Nicotinamide || Cyanocobalamin || Cocarboxylase

Pharmaceutical groups:

• Vitamins and vitamin-like products in combinations

lyophilisate for preparing a solution for intramuscular administration

On pharmacy shelves, the drug “Cocarnit” is presented by the manufacturer as a lyophilisate for the subsequent preparation of a parenteral solution, packaged in 3 ml dark glass ampoules. In consumer pharmaceutical packaging there are three to five cell contour blisters with three ampoules.

Additionally, a solvent is included - lidocaine in transparent ampoules, as well as detailed instructions.

lyophilized powder for the preparation of solution for injection.

Mode of application

If side effects from the central nervous system occur (dizziness, confusion), it is recommended to refrain from driving vehicles and other mechanisms.

1-2 ampoules are administered intramuscularly daily. Cocarnit injections are performed in courses, the duration of which depends on the severity of the disease.

The solution is used immediately after preparation; it should be red. If the color has not changed, it cannot be used.

The instructions for Cocarnit contain a warning about the need to monitor platelets and red blood cells, clotting time, bilirubin, uric acid and transaminases.

1-2 ampoules of the drug are administered intramuscularly once a day.

The duration of treatment and repeated courses depend on the nature and severity of the disease.

special instructions

Cocarnit in ampoules is sold in packaging together with an anesthetic auxiliary substance - Lidocaine. Before use, you must make sure that you are not allergic to this drug. If the reaction is positive, the drug is replaced with another similar medication.

After preparing the therapeutic composition, the injection is given immediately. Do not store the prepared solution, as this reduces its effectiveness.

The color of the prepared product should be red or pink. If the drug does not comply with the norm, do not use it.

During long-term treatment with Cocarnit, blood sugar levels, as well as the content of potassium and magnesium in the body, should be monitored.

Use in children

The medication is prohibited for use in the treatment of children under 18 years of age.

Experts do not recommend using Cocarnit during pregnancy and breastfeeding. If there is a need for treatment with a therapeutic agent, stop breastfeeding for a while.

Severe liver failure is a contraindication for the use of the drug.

If the symptoms of the disease worsen after 9 days of treatment, then course correction is required. Other special instructions for using Cocarnit:

1. During treatment, dose adjustment of hypoglycemic drugs and careful monitoring of the course of diabetes mellitus are required.
2. A properly prepared solution is pink in color. Do not use the drug if its color has changed.
3. The solution cannot be stored; it must be used immediately after preparation. Intradermal administration is prohibited.
4. During treatment with the drug, side effects from the central nervous system may develop in the form of dizziness and confusion, therefore it is not recommended to drive a car or operate dangerous machinery due to decreased concentration.

Composition of the support agent

The complex of its active substances makes the medicine highly effective:

• trifosadena disodium trihydrate;
• cocarboxylase;
• nicotinamide;
• cyanocobalamin.

It is this combination that promotes the rapid restoration of tissue metabolism.

Glycine and methyl parahydroxybenzoate, as well as propyl parahydroxybenzoate are auxiliary components, the purpose of which is to maintain and enhance the medicinal properties of the drug.

The body-supporting effect of the drug is ensured by its balanced mineral and vitamin composition. It includes such substances as:

• triphosadenine (10 mg);
• cocarboxylase (50 mg);
• cyanocobalamin (0.5 mg);
• nicotinamide (20 mg);
• 5-deoxyadenosylcobalamin;
• excipients (water, lidocaine, glycine).

Each substance in the composition performs its own function. Trifosadenine and cyanocobalamin stimulate metabolism, and cocarboxylase helps the body synthesize acids, proteins, lipids, and improves glucose absorption. 5-deoxyadenosylcobalamin also takes an active part in metabolic reactions. And nicotinamide has a positive effect on tissues, being one of the derivatives of vitamin PP.

https://www.youtube.com/watch?v=K_Y1-otMKvs

Nicotinamide 20 mg

Cocarboxylase 50 mg

Cyanocobalamin 0.5 mg

Disodium adenosine triphosphate trihydrate 10 mg.

Solvent: Lidocaine hydrochloride 10 mg.

Cocarnit - solution for injection

Just three weeks ago I took a course of the drug “Cocarnit”. Unfortunately, I threw away the packaging, but the impressions remain. Therefore, for those who are really interested, read without pictures. The drug is very good, knowledgeable doctors often recommend it. “Kokarnit” is produced in ampoules, in... Carniton is a combined drug, the effect of which is determined by the components included in its composition. This is a lyophilisate that is dissolved with lidocaine and administered intramuscularly. Includes the following substances: triphosadenine disodium trihydrate, Vitamin B12, cocarboxylase, nicotinamide in certain ratios indicated...

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Interaction with other drugs

The drug is a complex of two vitamins, one coenzyme and a metabolic substance.

Trifosadenine is a drug containing high-energy compounds that provide energy to the nervous system and heart muscle. Has hypotensive and antiarrhythmic effects. Dilates cerebral and coronary arteries. Improves the metabolism of nervous tissue.

Trifosadenine is a drug containing high-energy bonds that provide energy to the heart muscle.

Nicotinamide is a vitamin PP, involved in energy processes and reactions of the Krebs cycle. Improves carbohydrate and protein metabolism, cellular respiration. Reduces cholesterol levels.

Cyanocobalamin – vitamin B12. A deficiency of this substance leads to an unsteady gait, dysfunction of the spinal cord and peripheral nervous system. It is a donor of methyl groups to reduce the level of homocysteine, which is harmful to the cardiovascular system. Promotes cell regeneration.

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Cocarboxylase is a coenzyme of the enzyme carboxylase, which regulates the addition and detachment of carboxyl groups to alpha-keto acids. It is an antihypoxant and increases the resistance of the myocardium to oxygen deficiency. Reduces the concentration of lactate and pyruvate in cardiomyocytes and the body. Indirectly participates in the synthesis of nucleic acids, proteins, fats.

Pharmacokinetics

Trifosadenine is broken down in cells into phosphates and adenosine, which are included in the process of formation of the ATP molecule for the energy needs of the body, including nervous tissue and the heart.

Cyanocobalamin is transported by transcobalamin proteins into tissues, stored mainly by the liver, from where it is partially excreted by bile. Transforms into 5-deoxyadenosylcobalamin. Protein binding – 0.9%. Absorbed quickly after parenteral administration. The maximum concentration is reached an hour after the intramuscular injection.

Cyanocobalamin is stored mainly in the liver, from where it is partially excreted in bile.

Nicotinamide is quickly distributed throughout the body. Metabolized by the liver - nicotinamide-N-methylnicotinamide is formed. The half-life is 1.3 hours. Excreted through the kidneys, clearance 0.6 l/min.

The drug may cause side effects.

Nausea, vomiting, diarrhea are rare.

Increased number of red blood cells, leukocytes, platelets.

Excitement, headache, vertigo.

From the central nervous system, side effects such as headaches are possible.

From the skin and subcutaneous tissues - rashes, itching, redness of the skin, acne, sweating.

Quincke's edema, itching, rash.

From the side of the heart

Arrhythmia, tachy- and bradycardia, chest pain, decreased blood pressure.

Allergies

Anaphylactic shock, skin rash.

The patient may experience allergic manifestations in the form of a skin rash.

Cyanocobalamin is incompatible with vitamins B1, B2, B6, folic, ascorbic acid, heavy metals (De-nol, Cisplatin), alcohol.

Cyanocobalamin is incompatible with alcohol.

When used simultaneously with drugs from the biguanide group (Metformin) in cases of impaired glucose tolerance, aminoglycoside antibiotics, salicylates, potassium, colchicine, and anticonvulsants, the absorption of vitamin B12 is reduced.

To avoid hypercoagulation, do not use with agents that increase blood viscosity.

Cyanocobalamin is not compatible with Levomycetin.

Strengthens the vasodilator effect of Dipyridamole.

Purines – Caffeine, Theophylline – antagonists of the drug.

Nicotinamide enhances the effect of anti-anxiety, sedative and blood pressure-lowering drugs

Xanthinol nicotinate reduces the effect of the drug.

In patients using hypoglycemic agents of the biguanide group (metformin), due to impaired absorption of cyanocobalamin from the gastrointestinal tract, a decrease in the concentration of cyanocobalamin in the blood may be observed. No drug interactions have been described with other hypoglycemic agents.

Cyanocobalamin is incompatible with ascorbic acid, heavy metal salts, thiamine, thiamine bromide, pyridoxine, riboflavin, folic acid.

Cyanocobalamin should not be used simultaneously with drugs that increase blood clotting.

In addition, concomitant use of cyanocobalamin with chloramphenicol should be avoided.

Aminoglycosides, salicylates, antiepileptic drugs, colchicine, potassium preparations reduce the absorption of cyanocobalamin.

When combined with drugs containing triphosadenine and dipyridamole, the effect of dipyridamole is enhanced, in particular its vasodilating effect.

Dipyridamole enhances the effect of triphosadenine.

Some antagonism appears when the drug is used together with purine derivatives (caffeine, theophylline).

It should not be administered simultaneously with cardiac glycosides in large doses, as the risk of adverse reactions from the cardiovascular system increases.

When used simultaneously with xanthinol nicotinate, the effect of the drug is reduced.

Nicotinamide potentiates the effect of sedatives, tranquilizers, and antihypertensive drugs.

Headache, dizziness, tachycardia, allergic reactions (urticaria); with intramuscular administration, hyperemia, itching, swelling at the injection site.

If severe side effects develop, the drug

cancelled.

Cocarboxylase enhances the cardiotonic effect of cardiac glycosides.

The medicinal drug Cocarnit is presented in the form of a complex of metabolic substances and vitamins of different groups. The drug Cocarnit contains a substance such as nicotinamide, which is a vitamin complex whose structure is quite close to nicotinic acid. This substance has the following effects:

• There is an activation of redox functions in human cells and tissues.
• It turns out that nitrogen metabolism improves.
• The degree of atherogenic lipoproteins contained in the blood decreases.
• An antiallergic effect is formed.

Cocarboxylase, contained in the drug, is a coenzyme from a group of enzymes synthesized in the body. Such enzymes play a significant role in the process of carbohydrate and fat metabolism, and in addition, improve the absorption of glucose, normalize the transport of useful components and nourish human tissues.

Cyanocobalamin is a nutrient that contains cobalt. For the normal functioning of the human body, this microelement is essential. Some of its main tasks include:

1. Active participation in protein, fat and carbohydrate metabolism. In addition, the microelement helps accelerate the regeneration process in tissues.
2. It lowers the cholesterol level in the blood plasma and also eliminates the excessive accumulation of fat cells in the liver.
3. Has a positive effect on the functioning of the liver and nervous system.

Another important element included in the Cocarnit product is disodium adenosine. Its positive properties include:

• Decreased blood pressure.
• Dilates blood vessels.
• Reduces the occurrence of arrhythmia.

The drug Cocarnit is available only in the form of injections for injections. It has a pink powdery appearance that must be dissolved before vaccination. The kit includes a solvent and instructions for use. The rich composition of the drug allows it to provide therapeutic therapeutic effects on humans for various diseases. For what ailments the medication is used, we will find out in more detail.

Considerable importance should be given to such a factor as the interaction of the drug with other drugs. The manufacturer and experts do not recommend using Cocarnit with other types of medications, as this contributes to the occurrence of the following pathologies:

1. Increased risk of hyperkalemia. This pathology develops if the drug is taken together with diuretics.
2. The complex use of glycosides contributes to the occurrence of pathologies, as well as side symptoms of the cardiovascular system.
3. Reducing the amount of Lidocaine in the blood plasma through the combined use of Pethidine and Quinidine.
4. When combined with morphine, it is possible to provoke depression of respiratory function.
5. Increased risk of bleeding if combined with anticoagulants.
6. Complex treatment with inhibitors helps reduce blood pressure.
7. Cocarnit should not be used together with Xanthinol, since the latter significantly reduces the effectiveness of the former.

The manufacturer of the drug Cocarnit itself, and doctors do not recommend taking it together with other medications. This is due to the fact that unwanted reactions of the body may occur.

1. If the drug is taken in combination with diuretics, there may be a possibility of an increase in the level of potassium in the circulatory system;
2. When taking the drug Cocarnit together with glycosides, there is a risk of aggravating symptoms of cardiovascular diseases;
3. If a one-time dose of Pethidine, Quinidine with the drug Cocarnit is prescribed, this may cause a decrease in the dosage of Lidocaine in the blood plasma, instead of the prescribed administered dose;
4. If it is taken together with morphine, it can cause difficulty breathing;
5. Combination with an anticoagulant can lead to bleeding;
6. When taken together with an inhibitor, it can significantly reduce blood pressure;
7. Xanthinol reduces the effectiveness of Cocarnit, so it is not recommended to take them together.

Instructions for the use of Cocarnit injections

The metabolism-improving drug Cocarnit additionally regenerates nerve fibers of the peripheral nervous system. The medicine is produced by the Egyptian company EIPICo, belongs to the group of metabolic agents based on a complex of active components nicotinamide, cyanocobalamin, cocarboxylase and adenosine triphosphate.

Compound

The drug contains metabolic substances and vitamins that form a balanced complex. Component properties:

1. Trifosadenine is an adenosine derivative designed to stimulate metabolism. The substance has a vasodilating effect on the coronary and cerebral arteries, increases metabolism and provides energy to tissues. In addition, it has a hypotensive and antiarrhythmic effect, reduces blood pressure, relaxes smooth muscles, and improves the conduction of nerve impulses.
2. Cocarboxylase is an enzyme produced in the body from thiamine (vitamin B1). It is part of another carboxylase enzyme that catalyzes the carboxylation and decarboxylation of keto acids. The substance affects the synthesis of nucleic acids, proteins, fats, improves the absorption of glucose and tissue trophism. Cocarboxylase reduces the concentration of pyruvic and lactic acid.
3. Cyanocobalamin (vitamin B12) is metabolized in the body to methylcobalamin and 5-deoxyadenosylcobalamin. The first component promotes the conversion of homocysteine ​​to methionine and adenosylmethionine, participating in the formation of pyrimidine and purine bases, DNA and RNA. 5-deoxyadenosylcobalamin is involved in part of the metabolism of carbohydrates and lipids. Vitamin deficiency leads to impaired division of hematopoietic and epithelial cells and impaired formation of the myelin sheath of neurons.
4. Nicotinamide is a form of vitamin PP that is involved in redox reactions. The component regulates tissue respiration, improves carbohydrate and nitrogen metabolism.

Doctors prescribe Cocarnit injections strictly according to indications. Injections are effective for the following diseases and conditions:

• neuralgia of various origins;
• neuritis;
• symptomatic treatment of diabetic polyneuropathy, neuropathies of other origins;
• radiculitis, lumbago, sciatica;
• myalgia, bursitis, tendonitis;
• coronary heart disease, myocardiopathy, cardiac surgical myocarditis.

If Cocarnit is prescribed in ampoules, the instructions for use of the medicine should be studied carefully, since this medicine has its own characteristics of use.

To exclude the development of an allergic reaction, a test is done before treatment to determine the tolerability of the active components of the drug. If the patient’s well-being does not deteriorate and there are no redness, swelling or rashes on the skin, the medication can be used.

The therapeutic solution is administered intramuscularly (in some cases, subcutaneous and intravenous administration is allowed). The medicine for injection must be diluted using a solvent additionally included in the package.

Adhere to the following scheme:

1. The required amount of solution is drawn from the ampoule using a syringe and added to the bottle containing the dry mixture.
2. The composition is stirred well to obtain a homogeneous consistency.
3. The medicine is drawn into a syringe and injected deep into the gluteal muscle, into a place previously treated with alcohol.

The recommended daily dose is 2 ml.

The introduction of a therapeutic solution may provoke the development of adverse reactions from the body. The following undesirable effects are sometimes observed:

• attacks of headache and dizziness;
• increased or decreased heart rate;
• increased excitability;
• pain in the heart area;
• breathing problems;
• hypercoagulability;
• muscle spasm;
• increased body temperature;
• metallic taste in the mouth;
• increased sweating.

Treatment with the drug may be accompanied by general weakness and malaise. In case of hypersensitivity to the components of the drug, an allergic reaction develops, manifested by dermatitis, itching, and hyperemia. In rare cases, allergies can lead to angioedema and anaphylactic shock.

In case of an overdose of the drug the following are noted:

• tremor of the limbs;
• tachycardia;
• convulsions;
• heart failure;
• pulmonary edema;
• coma;
• increased side effects.

In such cases, stop using the medication and carry out symptomatic treatment.

Undesirable effects

The multicomponent nature of the Kokarnit product, the instructions for use confirm this, determines the wide range of pharmacological effects it provides:

• adenosine derivative - triphosadenine, has a stimulating effect on the course of metabolic processes in tissues, in addition, it has a vasodilating, energy-stimulating effect, moderately hypotensive and antiarrhythmic effect;
• cocarboxylase is a coenzyme that indirectly promotes the formation of nucleic acids, as well as proteins and beneficial lipids, and also significantly reduces the concentration of lactic and pyruvic acids, which improves the transfer of glucose into cells, so the trophism of nervous tissue increases;
• cyanocabalamin – participates in the correction of metabolic processes of carbohydrates and lipids;
• nicotinamide – actively participates in reductive and oxidative processes at the cellular level, which improves the course of metabolic processes and corrects tissue respiration.

All of the above pharmacological effects determine a wide range of uses of the drug in medical practice.

Since the drug has a multicomponent composition, during its administration, people may experience individual deterioration in health in the form of:

• persistent cephalgia;
• dizziness;
• severe weakness;
• tachycardia;
• dermal rashes;
• skin itching;
• anaphylactic shock;
• hives;
• hyperhidrosis;
• dyspeptic disorders;
• pulmonary edema;
• peripheral vascular thrombosis;
• bronchospasm;
• blurred vision.

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It is recommended to immediately notify the attending physician about each case of a sharp change in well-being during pharmacotherapy, so that therapy can be adjusted.

Pharmacokinetics

Reviews about the drug Cocarnit

Patients rarely describe a characteristic medication because they use it as part of a combination treatment. It is difficult to understand which medicine provided the positive dynamics, but Cocarnit’s merit is really present in this. Doctors speak positively about the properties of this medication and attribute to it a therapeutic effect for convulsions, numbness of the limbs, neuritis and other nervous disorders.

Some patients use Cocarnit as a preventive measure to relieve stress after an emotionally stressful day at work. When used correctly, side effects are excluded, so reviews about their occurrence on medical forums on the Internet were not found. Cases of overdose are described in isolated clinical pictures, but are only a consequence of the patient’s negligent attitude towards his own health.

Cocarnit is an effective medicinal product with pronounced metabolic properties at the cellular level. Its use has a beneficial effect on the nervous system and is an excellent prevention of stress and chronic insomnia.

Kokarnit's analogs

Analogues of the drug, characterized by a similar therapeutic effect, can be used if it is not possible to purchase Cocarnit (or there are contraindications and individual intolerance). You can check with your doctor which of the remedies is suitable for you as a replacement.

Among similar drugs, you can find products cheaper than Cocarnit, ampoules of which cost around 600 rubles. But there are medications that are more expensive, but still effective or suitable specifically for your case. Consulting a doctor before purchasing such drugs is required.

Experts recommend the complex product for use when pathological conditions require immediate restoration of tissue processes.

Main indications for use of the drug:

• various etiologies of neuralgia;
• neuritis and ischealgia;
• radiculitis and dorsopathies;
• neuropathy;
• myalgia and tendonitis;
• bursitis;
• myocardiopathy.

In rare cases, the use of the drug during the period of intrauterine development of the fetus is allowed - according to individual indications, if the benefit of therapy for the mother exceeds the possible risk for the baby.

For the treatment of diabetic polyneuropathy, analogues are prescribed:

1. Amitriptyline.
2. Trigamma.
3. Durogesic.
4. Cymbalta.
5. Gabagamma.
6. Vitaxon.
7. Carbamazepine.
8. Finlepsin retard.
9. Benfolipen.
10. Nicetyl.
11. Thiogamma.
12. Thiolepta.
13. Milgamma.
14. Thioctacid.
15. Lipothioxone.
16. Actovegin.
17. Octolipen.
18. Neurolipon.
19. Milgamma compositum.
20. Espa Lipon.
21. Finlepsin.
22. Combilipen.
23. Berlition 300.

There are no products with completely identical composition. However, there are metabolic drugs - Sodium adenosine triphosphate, Cocarboxylase, Nicotinic acid tablets, Cyanocobalamin.

Taurine (from 7.40 rubles), Taurine-DIA (from 9.73 rubles), Glycine (from 12.50 rubles), Lipoic acid (from 13.00 rubles), Glycine-MHPP (from 19.60 rubles)… Show all analogues of the drug Cocarnit » Attention: use of analogues must be agreed with the attending physician.

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The drug "Cocarnit": has no complete analogues; 100 analogues in action, the most similar is Combilipen tabs (214-463ք)

Diseases for selection

Doesn't interact with

Add diseases and medications so that the Cyberis artificial intelligence selects analogues that do not have dangerous contraindications or interactions with the drug administered.

The Egyptian company EIPICo once released Cocarnit, which has the ability to improve metabolism. The metabolic drug helps the regeneration of peripheral nerve fibers.

What is metabolism? This is a chemical reaction necessary for the vital support of the entire organism. If this process is disrupted, your health immediately worsens, your body weight increases, and general weakness and other negative conditions may appear. To normalize metabolism, you need to lead an active lifestyle and not eat excess food. In addition, Cocarnit is prescribed to restore metabolism.

Compound

The medication is packaged in glass ampoules, the powder is colored pink. There is a special liquid solution for diluting it.

Pharmacodynamics

Cocarnit is a vitamin complex that helps improve metabolism. The medicine has analgesic and neurometabolic properties that have a positive effect on the emotional and vegetative state. The drug owes its properties to its components.

Cocarboxylase

Available in glass bottles with a dosage of 50 mg. The constituent substances have the ability to increase access to cells of essential nutrients and oxygen. This improves energy metabolism and inhibits lactic acid. The active substances of the drug do not allow metabolic acidosis to occur. They help relax muscle tissue, resulting in reduced pulsation.

The drug Cocarboxylase is most often prescribed for heart diseases in the compensation stage, for diseases of a nervous nature, and for ketoacidosis in diabetes mellitus. In cases where there is insufficiency of cerebral blood flow.

The medicine is used for drug intoxication and for the treatment of infectious diseases. When using this medicine, the patient may have an allergy in the form of redness or rashes. There is a possibility of disruption of the gastrointestinal tract, decreased blood pressure, and bradycardia.

Korilip

Rectal suppositories Korilip are a Russian analogue of the drug Cocarnit. It contains the active substance - cocarboxylase, as well as auxiliary components: lipoic acid, vitamins and minerals. Helps improve the metabolic process, helps eliminate acidosis and hypoxia. Due to the properties of the substances, proteins and nucleic acids are formed, and the liver tissue is protected.

The medicine Korilip is indicated for use in diseases where oxygen starvation occurs. It is prescribed to patients suffering from chronic heart disease, infectious diseases, drug poisoning, and ketoacidosis. Also indicated for use in children.

Symptoms of adverse events after using the drug are rare. For example, an allergic rash, coughing, and sneezing may occur. Dyspeptic reactions include a gag reflex and nausea. Do not take the drug if you are intolerant to at least one of the active substances.

How is the Kokarnit complex used?

Among the injectable drugs administered intramuscularly or into the knee joints are:

• non-steroidal anti-inflammatory drugs: movalis, melbek, dikloberl, olfen;
• non-narcotic analgesics: ketorolac, ketalgin, dexalgin;
• glucocorticoid drugs: diprospan, dexamethasone, metipred, solu-cortef;
• chondroprotectors: alflutop, rumalon.

A coenzyme that plays an important role in the metabolic process of carbohydrates. Takes part in the synthesis of nucleic acid.

Hypoglycemic agents from the biguanide group (based on metformin), when used simultaneously with Cocanite, can interfere with the rate of absorption of cyanocobalamin from the gastrointestinal tract, reducing its concentration in the blood. Other drugs in the group do not show such an effect.

The mechanism of action of Cortexin is ensured by the activation of neurons and neurotrophic factors of the brain, due to which the transfer of information between brain structures occurs much faster and more efficiently.

Pregnancy and lactation

It is not recommended to use the drug Cocarnit during pregnancy.

It is recommended to stop breastfeeding during treatment with the drug.

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During pregnancy

should be used only if the expected benefit to the mother outweighs the potential risk to the fetus.

It is recommended to stop breastfeeding during treatment with the drug.

In the instructions of Cocarnita

The medicine Cocarnit is used only when injections are prescribed by a doctor. The injections must be administered by a person with at least minimal medical knowledge of human anatomy.

A list of diseases for which a doctor may prescribe treatment with Cocarnit. For example:

• Neuritis and neuralgic diseases of any origin;
• Pain in the spinal region with radiculitis, lumbago;
• Bursitis, myalgia;
• Myocarditis, stroke.

This remedy is not particularly indicated for pregnant women. In case of urgent need, it is taken with caution, as there may be a significant risk to the unborn child.

Contraindications

Cocarnit has many positive reviews, but despite this, not all patients can take it. A list of cases in which injections are strictly prohibited.

• If you observe a decrease in heart rate in a patient;
• For heart failure;
• In case of stroke or heart attack;
• If the patient suffers from bronchial asthma;
• A tumor was discovered;
• Stomach diseases, ulcerative colitis;
• Low/high blood sugar levels.

The package along with Cocarnit injections contains an anesthetic auxiliary substance - lidocaine. After the powder substance is dissolved with water, you also need to draw lidocaine into the syringe. But first you need to make sure that the patient does not have an allergic reaction to this drug. If the answer is yes, then Cocarnit should be replaced with another medicine.

If the patient has an allergy, then swelling, red rashes all over the body are detected, breathing becomes more frequent or health becomes worse. Allergies are dangerous because they can cause anaphylactic shock, which can lead to death.

Cocarnit should be administered strictly intramuscularly. Open the glass ampoule with the dry substance and the solution liquid, mix thoroughly until a homogeneous liquid is formed, and then draw up a sterile syringe. The injection site must be wiped with a disinfectant, such as alcohol.

The daily dosage is 4 ml: administer one ampoule of the medicine in the morning and evening. To eliminate symptoms, you will need to undergo a treatment course for 7-9 days. If there is no improvement during this period, the doctor prescribes stronger drugs.

The frequency of administration of Cocarnit and the total duration of the course of therapy are determined by the specialist on an individual basis. As a rule, the ready-made solution of the drug - lyophilisate is already diluted with lidocaine; it is recommended to inject it deeply into the gluteal muscle 1 time / day every day. After relief of general negative symptoms, 1 ampoule of the drug is required 2-3 times a week.

Monitoring of blood parameters during pharmacotherapy is not required, as is no adjustment of medication doses for treatment in elderly people.

Possible side effects and symptoms of overdose

The use of Cocarnit injections causes unwanted reactions in the body in very rare cases. Possible side effects include the following:

• allergic reaction, expressed by difficulty breathing, skin rash and Quincke's edema;
• hives;
• confusion;
• tachycardia or bradycardia;
• pain in the heart area;
• nausea and diarrhea;
• increased sweating;
• redness of the skin of the upper body and face;
• irritation at the injection site, accompanied by itching, burning and redness;
• headaches and dizziness.

Terms of sale

A drug

should be stored in a dry place, out of reach of children.

The average price of Kokarnit, lyophilisate (Moscow), is 658 rubles. You can buy medicine in Minsk for 14 – 18.5 bel. rubles The price of the drug in Kyiv is 215 hryvnia, in Kazakhstan – 2830 tenge. Dispensed by prescription.

You can purchase the drug Cocarnit only with an appropriate prescription from your doctor. The cost of the medicine in injections is 720 rubles for 3 ampoules. The medicine is produced by several manufacturers, so pricing can vary significantly. To avoid getting caught by a counterfeit, you should purchase the medicine exclusively from certified pharmacies.

The medicine should be stored exclusively in a dark place where access to children is limited. Improper storage of the drug will render it unusable, after which its use is strictly prohibited. Typically, the shelf life of the medicine from the date of release is 3 years if stored correctly. When purchasing a medication, be sure to pay attention to the release date. After the expiration date, the drug must be disposed of.

In conclusion, it should be noted that the drug has analogues, so if Cocarnita is not available in the pharmacy, then it can be replaced by: Cardonat, Actovegin, Vitaxon, Milgamma.

Instructions for the use of sulfocamphocaine injections

Cocarboxylase in the form of injections: features of the use of the drug

Dispensed by prescription. List B.

Price for Cocarnit

The price for 3 ampoules is 636 rubles.

Store in a dry place at a temperature of 15... 25°C.

Best before date

3 years. Solvent – ​​4 years.

At the moment, it is not possible to purchase this drug in Moscow pharmacies, since it is not registered in Russia. In this regard, the price of Cocarnit is unknown. Online pharmacies offer the drug at a price of 113.55 rubles. for 3 bottles.

Find the nearest pharmacies

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

On prescription.

Cocarnit is produced by several manufacturing companies. This factor significantly affects the pricing of the drug. If you buy the medicine in injections, then for three ampoules in glass you can pay 720-750 rubles. The drug is sold in pharmacy kiosks as prescribed by a doctor.

According to the instructions, it should be stored without exposure to daylight. Children's access to medicine should be limited. If the storage conditions are not properly met, Cocarnit will become unusable and will need to be disposed of, since the use of an unusable or expired drug is strictly prohibited. The shelf life of the medicine is three years.