The instructions for children's "Nazivin" allow you to use the medication to treat young infants. If the instructions are followed, the medicine is not harmful to health and has a therapeutic effect a few minutes after injection. The drug is available in different release forms and is actively used to treat respiratory tract infections and relieve inflammation.
The main active ingredient is oxymetazoline, due to which the drug has a vasoconstrictor effect. Excipients are benzalkonium chloride solution, sodium hydrogen phosphate, distilled water.
With the intranasal route of administration, swelling of the mucous membrane of the respiratory organs is reduced. When instilled into the eyes, redness and inflammation of the conjunctiva decreases. The result begins to appear 10 minutes after use and lasts for 6-8 hours.
Packaging and dosage form of the drug
The drug is offered in the form of nasal drops and spray. The different forms should be used taking into account the planned treatment.
Spray
For the convenience of carrying out medical procedures, “Nazivin” in the form of a spray is produced in bottles equipped with a sprayer. When injecting the medicine, the entire mucous membrane is irrigated, including hard-to-reach areas.
Nasal drops
Vasoconstrictor nasal drops are an almost transparent solution from colorless to pale yellow. Drops are available in tinted glass bottles with a built-in pipette cap. The bottles are packed in cardboard boxes.
Nazivin for children: reviews
Before use, consult a specialist
Most parents used the medication to treat nasal congestion in their children. They leave their reviews about the medicine, which are mostly positive.
“When my newborn baby had a stuffy nose, we immediately turned to the pediatrician for help. After examining our baby, he prescribed us Nazivin for children. Our baby's nose began to breathe after the first instillation. I liked the effect of this medicine,” says young mother Irina, 26 years old, in her reviews of the drug.
Read: Chinese calendar for determining the gender of a child
“I use Nazivin for children during pregnancy. Folk remedies for a runny nose did not help me and therefore I had to use more radical methods of treatment. Before using Nazivin, I consulted with a doctor and he approved of my decision. I used the product twice a day and its effect was completely enough for me” - this is a review from an expectant mother.
However, there are also cases like this: “I didn’t like Nazivin for children. Not only did it not give a positive therapeutic effect, I also began to develop allergies. They replaced it with another better drug.”
According to the reviews, we can conclude that Nazivin is a high-quality medicine that allows you to fight the disease, but there are people who were dissatisfied with the result of the treatment and complain about the appearance of unwanted effects. This may be due to self-medication or the use of the wrong dosage of the medicine. That is why you should definitely consult a doctor before using the drug.
Nazivin up to 1 year should be used only as prescribed by a doctor. This is a highly effective vasoconstrictor that can relieve nasal congestion. You should be aware that with the wrong dosage of the drug, various negative consequences may develop. Before using the drug, it is imperative to determine the causes of a runny nose, as well as the individual characteristics of the child.
The video shows tips for treating a runny nose in a baby:
16 Sep 2020 Yuki 409
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For what diseases is it prescribed?
There are a number of indications for the use of Nazivin. According to the instructions for use, the medication is prescribed for the following ailments:
- acute respiratory diseases arising from rhinitis;
- vasomotor and allergic types of rhinitis;
- inflammation of the middle ear;
- Eustachitis.
Also, the medicinal properties are useful in eliminating swelling before performing surgical operations. As prescribed by a doctor, it can be used for preventive purposes.
Indications and contraindications for the use of the spray for infants
Nazivin Sensitive is used as part of the symptomatic treatment of colds of the upper respiratory tract in infants. At this age, even a common runny nose can cause pneumonia, since the airways in infants are very narrow. Nazivin Sensitive can be used to treat various respiratory infections in newborns, including aspiration pneumonia.
If symptoms of the disease persist longer than 5 days, you should inform your doctor.
In addition, Nazivin Sensitive is effectively used for diseases such as:
- Acute infectious rhinitis;
- Allergic rhinitis;
- Vasomotor rhinitis;
- Sinusitis;
- Otitis media;
- Eustachite.
Nazivin Baby is not used for physiological rhinitis in newborns, since in principle it does not require the use of medications.
The main contraindications to the use of Nazivin Sensitive in children are:
- Individual intolerance to the components of the drug;
- Congenital pathologies of the heart, kidneys and lungs;
- Increased intraocular pressure;
- Urinary retention;
- Arrhythmia;
- Angle-closure glaucoma;
- Congenital renal failure;
- Hyperthyroidism;
- Congenital pathologies accompanied by high blood pressure;
- Thyrotoxicosis;
- Pheochromocytoma;
- Genetically determined atherosclerosis.
Nazivin should also not be used for diabetes. It should be used with caution when taking certain medications simultaneously. for example MAO inhibitors or bromocriptine.
Be sure to strictly follow the dosage prescribed by the doctor, since this can cause severe poisoning in a newborn.
Instructions for use during pregnancy in the first trimester
Nazivin is used with caution at any stage of pregnancy, as it can have a negative effect on the child’s body. At the same time, Nazivin Sensitive is one of the safest vasoconstrictor drugs in this case. It does not fail systemic action.
Nazivin Baby for small children and infants
According to the instructions, Nazivin Sensitive can be used to treat rhinitis of various origins, starting from 1 year. But in special cases, as prescribed by the attending physician, it can be used from the first day of the child’s life.
Rules and dosage regimen of the drug
The specific dosage depends on the age of the patient, existing diseases and current state of health. Before using the medication for the nose and other ENT organs, it is recommended to consult with your doctor. To ensure dosage accuracy, it is recommended to use a pipette with markings to indicate the number of drops.
For babies
For infants aged 1 month to one year, it is enough to instill 1-2 drops into each nasal passage. As an alternative method, you can soak cotton swabs in the solution and wipe the inside of your nostrils. The number of daily procedures is no more than three. The concentration of the medicinal solution should be no more than 0.01%.
From 1 year and older
For children over 1 year of age, only drops with a concentration of no more than 0.025% are prescribed. The standard dosage is 1-2 drops in each nasal opening 2-3 times throughout the day.
Pharmacological action and group of children's drug for newborns
Nazivin Sensitive belongs to the pharmacological group of vasoconstrictors, that is, vasoprotective and alpha-adrenomimetic drugs. Oxymetazoline hydrochloride constricts the blood vessels of the tissues of the nasal cavity and upper respiratory tract, relieves swelling of the mucous membrane and restores nasal breathing. It has an exclusively local effect, so this medicine can be used in children under 1 year of age.
Nazivin Sensitive gently reduces the outflow of mucus, reducing nasal congestion and irritation of the mucous membrane.
The drug contains a safe preservative, non-alkonium, which stops the further progression of a viral, bacterial or fungal infection through the respiratory tract. Sodium citrate in combination with citric acid monohydrate softens the nasal mucosa and accelerates metabolism.
Nazivin reduces swelling and redness of the mucous membrane not only in the nose. After 15 minutes, the positive effect spreads to the mucous membrane of the throat and conjunctiva of the eyes.
Nuances of using the drug
It is necessary to take into account a number of nuances of Nazivin therapy to achieve effective treatment in a short time. Compliance with the rules and recommendations will help avoid negative consequences and side effects.
For adults
If you use the drug via intranasal administration, the dosage for adults is 1-2 drops in each nostril 2-3 times a day or a similar number of spray injections with an interval of 10-12 hours. Adults and children over 12 years of age are recommended to use a solution with a concentration of 0.025-0.05%.
If Nazivin is prescribed to combat conjunctival edema, 1-2 drops are instilled into each conjunctival sac. If therapy is not effective, the frequency of use may be increased up to 4 times.
During pregnancy and lactation
Treatment with Nazivin during pregnancy and breastfeeding is permitted after comparing the expected effect for the mother and the probable danger to the child. An increase in the standard dosage is not allowed.
Nazivin children's drops for runny nose - instructions for use
If you are planning to purchase Nazivin for children (in drops, from 1 to 6 years), you should study the instructions first. Pay attention to indications and contraindications, assess the risk of side effects.
A child's body reacts more sharply to chemicals than an adult, so the risk of developing allergies and other negative reactions is higher.
When a drug is not suitable, analogues that provide a similar therapeutic effect are considered, even if they differ in composition.
Release form and composition
The drug is available in the form of nasal drops and spray. The active component is oxymetazoline hydrochloride. Its concentration varies: you can purchase Nazivin drops of 0.01, 0.025 and 0.05%. The product is available in bottles of 5 and 10 ml. The composition includes auxiliary components:
- benzalkonium chloride 50% solution;
- disodium edetate dihydrate;
- sodium dihydrogen phosphate dihydrate;
- sodium hydrogen phosphate dihydrate;
- sodium hydroxide 1 M solution;
- water.
Pharmacodynamics and pharmacokinetics
The active substance in the drug (oxymetazoline) belongs to the group of alpha-adrenergic agonists and anticognestants. It is used for various pathological conditions with localization of the lesion in the respiratory and hearing organs. This is due to the vasoconstrictor effect of the substance. Due to vasoconstriction, there is a decrease in swelling of the mucous membranes.
When using the drug, effects such as redness and irritation are not observed. Along with the decrease in swelling, the production of sputum from the nasal sinuses slows down. This makes breathing easier.
Symptoms of rhinitis weaken, they may disappear temporarily, but when the remedy stops working, the signs of the disease will return. Such changes in the patient’s condition are observed throughout the entire course of treatment with the drug, because
Nazivin does not eliminate the cause of the pathological condition.
Thanks to this remedy, aeration of the nasal sinuses and middle ear cavity is restored, and the development of bacterial infections is prevented. As a result, sinusitis or otitis media does not appear against the background of rhinitis.
Nazivin does not have a systemic effect on the body. It is distinguished by its ability to be quickly absorbed, as a result of which the patient’s condition immediately improves. The resulting effect lasts for 12 hours, then the symptoms of the disease return.
Instructions for use, dosage and rules of use
The drug is prescribed to children from birth, using a variety with a minimum concentration of the active component. It can be used to alleviate the condition of vasomotor and allergic rhinitis, respiratory diseases accompanied by copious sputum production or swelling of the mucous membrane.
Read more Drops Sideral for children - instructions and reviews
The medicine in different forms (spray and nasal drops) is used according to different schemes, which is due to the difference between the mechanisms of action.
Both products are delivered to the baby’s sinuses, but the spray irrigates the entire surface of the mucous membrane, and the drops are not sprayed, they are characterized by fluidity. When deciding which is better, spray or drops, you should take into account the patient’s age, because
this factor determines the sufficient concentration of the active substance in each case.
Drops for children under 1 year
For very young children use Nazivin baby for children from birth (from 0 to 1 year). The concentration of the active substance in this drug is 0.1%. For newborns (up to 4 weeks), a more gentle regimen is suitable.
Prescribe 1 drop in each nasal passage. Frequency of use: 2-3 times a day. For children from 5 weeks to 1 year, instillation is recommended with the same frequency. However, you can increase the amount of the drug to 2 drops if there is severe swelling and difficulty in nasal breathing.
Drops for children over 1 year
In this case, a more concentrated solution is used - 0.025%. The treatment regimen is the same as for children from 5 weeks to 1 year: 1-2 drops of the product are administered into each nasal passage, frequency of application is up to 3 times a day. If the swelling is not severe, you can put drops in your nose only in the morning and evening. This scheme is used to treat children under 6 years of age.
Older patients are prescribed drops with a concentration of the active component of 0.05%. Amount of product for one-time instillation: 1-2 drops. The frequency of its use is 2-3 times a day. It is not recommended to exceed the indicated dosages, as this may lead to negative consequences.
Spray application
The medicine in this form contains an average dose of the active substance, so it can be used as part of complex therapy in children from 1 year to 6 years.
Patients older than this age are prescribed an increased amount of the drug, and the spray is not suitable for newborns; in this case, reduced doses must be used. The application regimen is standard: 1 injection 2-3 times a day.
The duration of treatment should not exceed 7 days. If necessary, a second course of therapy is carried out after a few days.
Contraindications of the drug
Nazivin is not prescribed in a number of cases, including:
- rhinitis, accompanied by atrophic processes in tissues;
- angle-closure glaucoma;
- intolerance to the active component.
Read more Instructions for using Dexatobropt eye drops
Different forms of the drug have different age restrictions, which should be taken into account.
Use with caution
There are a number of pathological conditions in which it is permissible to use Nazivin, but therapy is carried out under the strict supervision of a doctor, since it is important to monitor the patient’s condition. Relative contraindications:
- increased intraocular pressure;
- during pregnancy and lactation, the drug is prescribed if the probable benefit outweighs the possible harm;
- recent use of monoamine oxidase inhibitors, Nazivin is allowed to be used 10 days after the end of the course of treatment with drugs of this group;
- thyrotoxicosis;
- diabetes;
- severe diseases of the cardiovascular system, such as hypertension, accompanied by frequent crises, as well as angina pectoris.
Side effect
Possible reactions:
- dryness of the mucous membranes of the sinuses;
- frequent sneezing;
- burning in the nose;
- Long-term use contributes to the development of tissue atrophy and drug-induced edema.
After the end of the action of Nazivin, a sharp deterioration in the condition is observed: nasal breathing becomes difficult, swelling intensifies. Sputum is not always released. A runny nose can only be accompanied by a deterioration in the respiratory function of the nose.
Nazivin overdose
If a large amount of the drug enters the body, for example, with repeated instillation of the drug in significant volumes, some patients develop signs of tachycardia and blood pressure increases. Other symptoms:
- nausea;
- fatigue;
- headache;
- restless state;
- sleep disturbance.
If the drug is accidentally taken orally, the following symptoms may occur:
- cyanosis;
- nausea;
- vomit;
- pupils constrict;
- abnormal heart rate;
- collapse;
- temperature increase;
- impaired respiratory function, including due to pulmonary edema;
- hypertension.
Some patients develop bradycardia, and symptoms of nervous system dysfunction and mental disorders may appear. Rarely, coma is a consequence of decreased central nervous system function.
To speed up recovery, stop the development of pathologies, and eliminate negative manifestations, use any sorbent, such as activated carbon.
You can remove toxins faster if you first rinse your stomach.
special instructions
Do not use drops for longer than recommended by the manufacturer. Nazivin should be used especially carefully to treat children, since patients in this group react more acutely to changes in the treatment regimen and increasing the dose of the drug.
After using increased doses of this drug, disturbances in the functioning of the central nervous system and cardiovascular system may occur. This means that you need to drive with caution, and if the above negative reactions occur, you should refrain from driving for a while.
Interaction with other drugs
You cannot use different vasoconstrictor drops at the same time. This will lead to an increase in their effect. As a result, the risk of developing negative reactions increases. Nazivin increases blood pressure when used simultaneously with MAO blockers and tricyclic antidepressants.
Read more Instructions for using Tobradex eye drops
Analogs of children's drops Nazivin
If the medicine in question is not suitable for some reason, you can pay attention to substitutes:
Vibrocil
Available in the form of drops, the medicine contains other active ingredients: phenylephrine, dimethindene maleate. This means that the drug can be used if Nazivin provokes a negative reaction.
Vibrocil is used to relieve symptoms of allergies and vasomotor, chronic rhinitis. The medicine eliminates swelling and makes breathing easier during colds. Contraindications for Vibrocil are similar to Nazivin.
It should be taken into account that children under 6 years of age are prescribed the drug in the form of drops.
Nazol Baby
Available in the form of drops. It is distinguished by a moderate vasoconstrictor effect, which is due to its composition: phenylephrine acts as the active ingredient.
The mechanisms of operation of this medicine and Nazivin are similar: blood vessels constrict, swelling is eliminated, and the intensity of sputum production is reduced. Nazol is approved for children 1 year and older. The contraindications for this drug and Nazivin are the same.
The difference between the medications is the limited use of Nazol Baby. It should not be taken for more than 3 days.
When choosing analogues, you need to be careful and study the instructions, since most vasoconstrictor drugs are intended for children over 6 years old. Some drugs come in different forms. If the spray is not used in the treatment of infants, then the drops have a wider area of application.
Reviews about the drug
Marina, 33 years old, Saratov:
Nazivin had to be given to the child at six months. Then a runny nose appeared for the first time, the nose was stuffy, so it was necessary to quickly relieve the condition. The drops helped immediately, since then I have had to use them more than once, but the product always helps out. After 1 year, we switched to a drug appropriate for the baby’s age.
Nina, 43 years old, Vladivostok:
I like children's Nazivin in the form of a spray better, as it irrigates the mucous membranes in the nose. The drops do not cover the entire surface that is swollen. I like the speed of the medicine, but Nazivin does not eliminate the cause of rhinitis, so I used it alternately with a local antibacterial agent.
You can purchase the product for 155-165 rubles/bottle. The difference in price is due to differences in release form and bottle volume. The drug is available at the pharmacy without a prescription.
Source: https://infofarma.ru/kapli/nazivin-detskij
Side effect
Taking medication outside of the restrictions or significantly increasing the standard dosage leads to side effects. Local reactions include dryness and a burning sensation of the mucous membrane, from the digestive system - attacks of nausea, from the central nervous system - a feeling of constant fatigue, migraines, sleep disturbances, and a feeling of anxiety.
Prolonged continuous use can provoke mucosal atrophy, tachyphylaxis and drug-induced rhinitis.
In case of a significant overdose of the drug or internal use, there is a pronounced constriction of the pupils, attacks of vomiting, an increase in temperature, an abnormal heart rate, respiratory distress, and swelling of the lungs. If there are side effects, it is recommended to consult a doctor and undergo symptomatic therapy. You should also consult a doctor if you need to treat with Nazivin for more than 5 days in a row.
Contraindications
- atrophic rhinitis;
- angle-closure glaucoma;
- children under 6 years of age (drops and nasal spray 0.05%);
- hypersensitivity to the components of the drug.
Carefully _
should be prescribed with the simultaneous use of MAO inhibitors and other drugs that increase blood pressure, as well as for up to 10 days after discontinuation of these drugs; with increased intraocular pressure; during pregnancy and lactation; in severe forms of cardiovascular diseases (angina pectoris); with thyrotoxicosis and diabetes mellitus.
Children's Nazivin: instructions for use, up to 1 year, drops and spray
A child's runny nose causes inconvenience not only to the sick baby, but also to his parents. Due to nasal congestion, the child sleeps poorly, eats poorly and is capricious a lot.
If measures are not taken at the initial stage, a runny nose will affect the throat, a cough will develop, and there will be a possibility of a serious complication, otitis media.
Pharmacies offer a huge list of medications that can alleviate the course of the disease, but not all of them are suitable for early childhood. One of the most successful medications suitable for young children is Nazivin.
General information about the drug
Nazivin is a vasoconstrictor drug for topical use that effectively combats swelling of the mucous membrane.
Experts recommend it for the treatment of rhinitis in children, and the dose and form of release are prescribed based on the patient’s age.
The greatest effect from using the medicine occurs after 15 minutes, and its effectiveness remains for 8–10 hours after treatment of the mucous membrane. This property allows you to use the drug before bedtime to relieve symptoms and provide the baby with a comfortable rest.
The use of Nazivin protects the upper respiratory tract from infection, and due to the fact that the middle ear is saturated with air, the likelihood of developing bacterial complications is reduced. The drug does not cause redness and does not irritate the mucous membranes.
The principle of action of the drug is based on the ability of oxymetazoline to influence alpha-2 adrenergic receptors located in the vessels of the nasal mucosa. The vessels narrow, the swelling subsides and the volume of discharge decreases significantly. Nazivin helps to quickly restore normal breathing through the nose. The drug is not absorbed into the blood and has only a local effect.
Composition and release forms
The active ingredient is oxymetazoline hydrochloride. The drug also includes:
- Citric acid monohydrate.
- Sodium citrate dihydrate.
- Glycerol.
- Benzalkonium chloride.
- Purified water.
Nazivin is produced in the form of a liquid with a yellowish tint. Release forms vary depending on the concentration of the active substance and packaging:
- Drops 0.01%.
- Drops 0.025%.
- Drops 0.05%.
- Spray 0.05%.
Drops are produced in glass bottles with a pipette cap, and spray bottles are made of plastic and have a sprayer that allows you to evenly distribute the medicine over the mucous membrane.
Indications for use
Nazivin is recommended for use in the following cases:
- The occurrence of rhinitis caused by ARVI.
- Allergic rhinitis, accompanied by swelling of the mucous membrane.
- Vasomotor rhinitis.
- If necessary, ensure effective drainage of the paranasal sinuses in the case of sinusitis, sinusitis, otitis media and eustachitis.
- Nazivin is also used to prepare the nasal cavity before surgical treatment.
Contraindications and possible side effects
You will have to stop using the drug if:
- The child may have an allergic reaction to the components of the medicine.
- When diagnosing atrophic rhinitis, a pathological condition in which the mucous membrane is deformed and the nerve endings in it die.
- In the presence of closed-angle glaucoma.
Particular caution is required when prescribing Nazivin in the following cases:
- When prescribed simultaneously with MAO inhibitors and within ten days after their discontinuation.
- With increased intraocular pressure.
- During pregnancy and during breastfeeding.
- In the presence of severe cardiovascular diseases.
- With thyrotoxicosis.
- If you have diabetes.
Side effects
Side effects when using Nazivin are rare, but studies confirm that the following reactions are possible:
- Feeling of burning and dryness in the nose.
- Sneeze.
- After the medication wears off, you may experience a feeling of nasal congestion and reactive hyperemia.
- In rare cases, reactions from the central nervous system are possible - insomnia, headache, fatigue and anxiety.
- Nausea.
- With frequent, repeated overdoses, tachycardia and arterial hypertension may occur.
- Using the drug for more than 5 days may lead to drug-induced rhinitis.
Overdose
When taken orally or repeated overdoses, the following may occur: nausea, vomiting, cyanosis, tachycardia, arrhythmia, etc. In addition, the functions of the central nervous system are inhibited, accompanied by drowsiness, bradycardia, decreased temperature and respiratory arrest.
An overdose is treated by gastric lavage and taking absorbents, such as charcoal.
How to take and dosage for children
Drops for babies under 1 year have a concentration of 0.01%.
The scheme for using Nazivin for newborns is as follows:
- In the first month of life (up to 4 weeks), 1 drop is dripped into each nostril 3 times a day. Measure out the required amount of medication using the pipette included with the bottle.
- From the second month, the number of drops can be increased to 2, the number of applications remains the same.
The drug can be administered in two ways:
- Instill directly into the nose using a pipette.
- Wipe the mucous membrane with a cotton swab dipped in the medicine. This method is often used in infants.
Drops for children from 12 months to 6 years are available in a dosage of 0.025%. They are administered 3 times a day, 1–2 drops.
Nazivin at a concentration of 0.05% is intended for children over 6 years of age and adults. Instillation should be done no more than three times a day, 2 drops in each nostril.
ATTENTION! Treatment with Nazivin should not last more than 3–5 days.
Nazivin Sensitive spray is available in dosages of 0.025 and 0.05%. This medication option is not suitable for infants, however, for children over one year of age the spray is convenient to use. A special feature of the spray is the uniform application of the drug to the mucous membrane, due to which the effect is achieved faster.
During treatment it is necessary to make 1 injection 3 times a day. Just like drops, the spray cannot be used for longer than 5 days.
special instructions
Please note that after purchase Nazivin must be stored in a dark place at a temperature not exceeding 25 degrees. Also, the medicine should be kept out of the reach of children.
The shelf life of Nazivin is 3 years from the date of release.
Do not use expired medications - this can seriously harm your health.
Analogues of the drug
Analogues of Nazivin are drugs based on oxymetazoline - Afrin, Nazol, Noxprey, Fazin. However, all these drugs are produced with a dosage of 0.05% and are prohibited for children under one year of age. Analogue drugs acceptable for use in infants are Oxyfrin and Sialorrino at a dosage of 0.01%.
Other drugs often prescribed by pediatricians for children under 1 year of age:
- Aquamaris. Drops based on sea water relieve inflammation and swelling. Allowed from birth.
- Nazol Baby. The active ingredient, phenylephrine, has a vasoconstrictor effect and relieves swelling of the mucous membrane.
- Protargol. Has an antibacterial effect and contains silver proteinate. Silver is not absorbed into the blood; the drug acts locally.
Children's Nazivin is used when you need to quickly and effectively solve the problem of nasal congestion in a small patient. If you follow the doctor's recommendations, this drug effectively fights the runny nose and does not cause discomfort to the baby.
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Source: https://prof-medstail.ru/zdorove-rebenka/detskij-nazivin
Dosage
Nazivin drops are intended for intranasal use.
Adults and children over 6 years old
drops of 0.05% should be prescribed, 1-2 drops in each nostril 2-3 times a day.
Children aged 1 to 6 years
drops of 0.025% should be prescribed, 1-2 drops in each nostril 2-3 times a day.
Children under 1 year of age
drops of 0.01% are prescribed.
Newborns
(children under 4 weeks of age) administer 1 drop into each nostril 2-3 times a day.
Children aged 1 month to 1 year
Prescribe 1-2 drops in each nostril 2-3 times a day.
To ensure dosage accuracy, the bottle of 0.01% drops has a graduated pipette with markings on the number of drops. If 1 drop is prescribed, then the pipette should be filled with the solution to the 1 mark.
The following procedure has also been proven effective: depending on age, 1-2 drops of a 0.01% solution are applied to cotton wool and wiped over the nasal passages.
Nazivin should be used for 3-5 days. Doses higher than recommended are prescribed at the discretion of the physician.
Nazivin Children up to 1 year and older: instructions for use of drops and spray, analogues
The condition of a child with a cold is often aggravated by nasal congestion. It is difficult for the child to fall asleep, he does not eat well and is constantly capricious because he cannot breathe freely. In pediatric practice, for such conditions, it is customary to prescribe vasoconstrictor medications, which include Nazivin.
The drug causes the blood vessels to narrow reflexively. Swelling decreases, the amount of mucus secreted decreases, and snot acquires a thicker consistency. As a result, the baby feels relief, his nasal breathing becomes free.
Description of the drug
Nazivin drops and spray are included in the group of alpha-adrenomimetic drugs. Their characteristic feature is a pronounced vasoconstrictor effect. Nazivin for children has a mild effect on the child’s body. It is prescribed to infants from the first days of life.
The active substance is oxymetazoline. Auxiliary components ensure the integrity of the solution and increase the therapeutic effect of oxymetazoline. Medicines in the form of drops and sprays are intended for local use, so they do not have a systemic effect on the body.
Operating principle of Nazivin
The vasoconstrictor components in Nazivin help relieve nasal congestion, relieving swelling and inflammation in the nasal cavity. If you follow the instructions and strictly dose the drug, then you will be able to restore nasal breathing 2 minutes after use.
The effect of taking the medicine will be long (about 12 hours). Restoring aeration will alleviate the baby’s condition, help him eat normally and sleep well. Nazivin is able to prevent the addition of a secondary bacterial infection (sinusitis, sinusitis, otitis media, etc.).
The active component oxymetazoline has a local effect. When it enters the mucous membranes of the nasal cavity, vasoconstriction occurs, thereby relieving tissue swelling and restoring the natural patency of the upper respiratory tract.
The auxiliary component benzalkonium chloride is included in the drug as a preservative. It prevents mold and bacteria from actively multiplying, which reduces the risk of further spread of infection.
To maintain the acid-base balance of the nasal cavity, sodium citrate and citric acid were included in Nazivin. These components improve the condition of the nasal mucosa and accelerate metabolic processes. Gilzerol is designed to soften and moisturize the ciliated epithelium of the inner membranes of the nose.
Forms of release of the drug
Nazivin Baby 0.01% is prescribed to newborns from the second day of life, it is often further diluted. A transparent solution with a yellow tint is available in small dark glass bottles of 5 ml with a pipette.
Other release forms:
- nasal drops 0.025% and 0.05% in a dark glass bottle with a 10 ml pipette;
- Nazivin Sensitive spray 0.05% in a 10 ml polyethylene bottle (enough for an average of 220 sprays).
Children's Nazivin in drops (Baby)
Nasal drops marked Baby are prepared on a water basis. The concentration of the active substance is 0.01%. The small bottle is equipped with a pipette cap, thanks to which you can accurately dose the medicine.
For the medicine to work, it must be instilled into each nostril. If the parents of a newborn are afraid of an overdose, then the baby solution can be diluted with saline or distilled water at a ratio of 1:1.
For children over 1 year of age, experts recommend using the drug with a higher concentration. In this case, it is better to use Nazivin 0.025% nasal drops.
Spray Nazivin Sensitive
The children's drug in the form of a spray is easy to dose; there is no need to accurately determine the amount of liquid using a pipette. With each injection, as much medicine reaches the mucous membranes as is necessary to achieve the desired therapeutic effect. The drug Nazivin Sensitive is intended for children over six years of age. One dose contains 22.5 mcg of active substance.
The solution in spray form is easy to use and economical. According to many experts, due to its wide spraying, children's spray irrigates the nasal mucous membranes better than drops.
Indications for use
Most often, the pediatrician prescribes nasal drops for children with nasal congestion with symptoms of acute respiratory viral infections and acute respiratory infections. Also, nasal drops and spray may be indicated for:
- allergic rhinitis;
- vasomotor rhinitis;
- eustachitis;
- inflammation of the middle ear.
Often, vasoconstrictor drugs are prescribed for drainage of the paranasal sinuses in case of sinusitis, sinusitis, etc. If a small patient has to undergo diagnostic procedures, then the nasal solution will help relieve swelling and inflammation in the nasal passages.
Without consulting a specialist, you should not resort to using such drugs to treat runny nose in infants.
Instructions for use
The method of use and dose of the medicine is determined by the attending physician. When using Nazivin 0.05% spray to treat children over 6 years of age, it is recommended to do 1 injection into the nostrils.
You can use the medicine no more than 3 times a day. The course of treatment does not exceed 3–5 days, unless otherwise agreed with the doctor. Nazivin Sensitive spray 0.025% has been released for children aged 1 to 6 years.
It also needs to be sprayed into the nose 2-3 times a day.
Children over 6 years old can use nasal drops, where the concentration of the active substance is 0.05%. Using a pipette, 1-2 drops of solution are injected into each nostril 2-3 times during the day.
For children under 6 years of age, 1 drop of Nazivin Baby 0.025% is dripped into each nasal passage. The procedure should be repeated 2-3 times.
Newborns and infants up to one year of age are prescribed Nazivin 0.01% solution. In order to drop the recommended dose of the drug into the baby’s nose, you need to draw liquid into the pipette up to the -1- mark. One drop of the drug should fall into the right and left nostrils.
This must be done carefully to prevent the drug from getting into the eyes. The child may twitch or turn sharply, so during the procedure you need to firmly fix his head. The medicine is instilled 2-3 times a day.
The duration of therapy when using Nazivin in the form of drops should not exceed 3-5 days.
In what cases is the drug contraindicated?
Knowing that Nazivin Baby can be used to treat children in the first year of life, many parents do not take into account contraindications, considering the medicine to be absolutely safe. However, oxymetazoline nasal solution may be contraindicated for use in some cases. Ignoring this point in the instructions for use often leads to the development of side effects.
The drug should not be taken by children with the following conditions:
- intolerance to the components of the drug;
- atrophic runny nose;
- kidney, liver and heart diseases;
- increased blood pressure due to pheochromocytoma, essential hypertension or atherosclerosis;
- endocrine disorders;
- angle-closure glaucoma;
- diseases requiring the use of MAO inhibitors.
Possible side effects
If you follow your doctor's recommendations and strictly follow the instructions, then side effects when taking Nazivin occur extremely rarely. Most often they are caused by an overdose of the drug when a child accidentally swallows the contents of the bottle. It is important that the medicine is kept out of the reach of children.
If the dose of the drug is exceeded, the patient may experience the following symptoms:
- nausea and vomiting;
- breathing problems;
- constriction of the pupils;
- increase in the number of heart contractions;
- pulmonary edema;
- a sharp decrease in blood pressure;
- increased body temperature;
- cyanosis (blueness of the skin and mucous membranes);
- vascular dysfunction.
Sometimes the baby experiences disturbances in the functioning of the central nervous system. Body temperature and blood pressure drop, and the patient enters an apathetic state. At the same time, he constantly feels sleepy. This often leads to cardiac and respiratory arrest. The baby may fall into a coma.
To prevent an overdose from causing serious health problems for the child in the future, if one or more of the above symptoms appear, you should immediately seek medical help. In the hospital, the patient will undergo gastric lavage and be prescribed appropriate treatment.
Also, you should not use the drug for more than 5 days. If you do not follow this rule, the effect of the drug will gradually decrease.
Long-term use of vasoconstrictor nasal drops or spray will lead to atrophy of the nasal mucosa, and the ciliated epithelium will lose its basic functions.
In this case, the person loses the ability to breathe freely without droplets, and he develops drug-induced rhinitis. It is possible to get rid of a constantly clogged nose by using corticosteroids.
Analogues and cost
Pharmacies offer a wide range of drugs designed to relieve nasal congestion. If we talk about analogues of Nazivin, then first of all we need to focus on drugs that contain oxymetazoline. These drugs include: Nazol, Noxprey.
The following have similar effects to Nazivin:
For the treatment of children, it is better to give preference to Pinosol, since it contains substances of plant origin. Otrivin is almost identical in strength and duration of action to Nazivin (price 100-150 rubles). Tizin drops are cheaper, but they last no longer than 2 hours.
Source: https://www.deti34.ru/aptechka/preparaty/nazivin-detskij-instrukciya.html
Side effects
Local reactions:
sometimes - dryness and burning sensation of the nasal mucosa, sneezing, in rare cases (after the end of Nazivin's action) - a feeling of nasal congestion (reactive hyperemia).
From the side of the central nervous system:
rarely - anxiety, insomnia, fatigue,.
From the digestive system:
rarely - nausea.
From the cardiovascular system:
with repeated overdose, arterial hypertension and tachycardia are possible.
Long-term continuous use of vasoconstrictor drugs can lead to tachyphylaxis, atrophy and recurrent swelling of the mucous membranes of the nasal cavity (rhinitis medicamentosa).
Overdose
Symptoms:
with a significant overdose or ingestion, constriction of the pupils, nausea, vomiting, cyanosis, increased body temperature, tachycardia, arrhythmia, collapse, cardiac depression, arterial hypertension, pulmonary edema, and respiratory disorders may be observed. In addition, mental disorders may be observed, as well as depression of central nervous system function, accompanied by drowsiness, decreased body temperature, bradycardia, arterial hypotension, respiratory arrest and possible development of coma.
Treatment:
gastric lavage, taking activated carbon.
Chin Kou Medical Instruments Co. Ltd. MERCK SHARP & DOHME BV Merck Selbstmedikation GmbH/Pharmaster Merck KGaA Merck KGaA for Nycomed Ursafarm Arzneimittel GmbH/Merck Selbstmedicati Ursafarm Arzneimittel GmbH/Merck KGaA & Co. Werk Pharmaster/Merck KGaA & Co. Werk Spittal
Country of origin
Germany Germany/Austria Russia France/Austria France/Germany
Product group
Respiratory system
Anticongestant - vasoconstrictor (alpha-adrenergic agonist).
Release forms
- 220 doses - polyethylene bottles with a dosing device (1) - cardboard packs. 10 ml bottle with a pipette cap 10 ml bottle 10 ml bottle with a pipette cap 5 ml bottle with a pipette cap polyethylene bottle (bottle) with a dosing device 5 ml, cardboard pack 1
Description of the dosage form
- Nasal drops nasal drops Nasal spray 0.05% Dosed nasal spray
pharmachologic effect
Nazivin® Sensitive (oxymetazoline) has a vasoconstrictor effect. When applied topically to the inflamed mucous membrane of the nasal cavity, it reduces swelling and nasal discharge. Restores nasal breathing. Elimination of swelling of the nasal mucosa helps restore aeration of the paranasal sinuses and middle ear cavity, which reduces the likelihood of bacterial complications (sinusitis, sinusitis, otitis media). When used locally intranasally in therapeutic concentrations, it does not irritate or cause hyperemia of the nasal mucosa. Oxymetazoline begins to act quickly, within a few minutes. The duration of action of Nazivin® Sensitive is up to 12 hours.
Pharmacokinetics
When administered locally intranasally, oxymetazoline does not have a systemic effect. The half-life of oxymetazoline when administered intranasally is 35 hours. 2.1% of oxymetazoline is excreted in the urine and about 1.1% in the feces
Special conditions
With caution In patients taking monoamine oxidase inhibitors and other drugs that increase blood pressure for up to 10 days after their use; with increased intraocular pressure, during pregnancy and lactation, with severe forms of cardiovascular diseases (hypertension, angina); with thyrotoxicosis and diabetes mellitus. Pregnancy and lactation When used during pregnancy or breastfeeding, do not exceed the recommended dosage. The drug should be used only after a careful assessment of the risk-benefit ratio for the mother and fetus. Special instructions Long-term use and overdose of the drug should be avoided, especially in children
Compound
- Nazivin 0.01% – Oxymetazoline hydrochloride 0.1 mg; Excipients: Citric acid monohydrate 0.6093 mg Sodium citrate 3.823 mg Glycerol (85%) 24.348 mg Benzalkonium chloride (50% solution) 0.100 mg Purified water 979.020 mg (for 0.1%) Nazivin 0.025% – Oxymetazoline hydrochloride 0.25 mg; Excipients: Citric acid monohydrate 0.6093 mg Sodium citrate 3.823 mg Glycerol (85%) 24.348 mg Benzalkonium chloride (50% solution) 0.100 mg Purified water 978.870 mg (for 0.25%) Nazivin 0.05% – Oxymetazoline hydrochloride 0 .5 mg; Excipients: Citric acid monohydrate 0.6093 mg Sodium citrate 3.823 mg Glycerol (85%) 24.348 mg Benzalkonium chloride (50% solution) 0.100 mg Purified water 978.600 mg (for 0.5%) Nazivin® Sensitive 11.25 mcg/dose – Oxymetazoline hydrochloride 0.250 mg Excipients: Citric acid monohydrate 0.609 mg Sodium citrate dihydrate 3.823 mg Glycerol (85%) 24.921 mg Purified water 978.397 mg (for 11.25 mcg/dose) Oxymetazoline 0.250 mg; Auxiliary ingredients: citric acid monohydrate, sodium citrate dihydrate, glycerol /85%/, water Oxymetazoline 0.500 mg; Excipients: citric acid monohydrate, sodium citrate dihydrate, glycerol /85%/, water Oxymetazoline hydrochloride 0.100 mg Excipients: Citric acid monohydrate 0.609 mg Sodium citrate dihydrate 3.823 mg Glycerol (85%) 24.921 mg Purified water 978.547 mg Oxymetazoline hydrochloride 0.5 mg Excipients: Citric acid monohydrate 0.6093 mg Sodium citrate 3.823 mg Glycerol (85%) 24.348 mg Benzalkonium chloride (50% solution) 0.100 mg Purified water 978.600 mg
Nazivin indications for use
- - acute respiratory diseases with symptoms of rhinitis; - acute allergic rhinitis; - exacerbation of vasomotor rhinitis; - to facilitate the outflow of discharge from the paranasal sinuses in case of sinusitis, eustachitis, otitis media; — to eliminate swelling before diagnostic manipulations in the nasal passages
Nazivin contraindications
- Inflammation of the mucous membrane of the nasal passages without secretion, chronic heart failure, hyperthyroidism, diabetes mellitus, pregnancy, children under 6 years of age (for eye drops), increased sensitivity to oxymetazoline, atrophic rhinitis, lactation, arrhythmias, severe atherosclerosis, arterial hypertension, chronic renal failure , angle-closure glaucoma.
Nazivin dosage
- 0,01% 0,025% 0,05%
Nazivin side effects
- Sometimes: burning or dryness of the nasal membranes, sneezing. In rare cases: after the effect of using Nazivin® wears off, a strong feeling of “stuffiness” in the nose (reactive hyperemia). Repeated overdose with local nasal use sometimes leads to systemic sympathomimetic effects such as increased heart rate (tachycardia) and increased blood pressure. In very rare cases, anxiety, insomnia, fatigue, headaches and nausea have been observed. Long-term continuous use of vasoconstrictor drugs can lead to tachyphylaxis, atrophy of the nasal mucosa and recurrent swelling of the nasal mucosa (rhinitis medicamentosa).
Drug interactions
Slows down the absorption of local anesthetic drugs and prolongs their effect. In patients taking monoamine oxidase inhibitors (MAOIs) during the previous 2 weeks and within 2 weeks after their discontinuation, tricyclic antidepressants or other drugs that increase blood pressure - increased blood pressure. Co-administration of other vasoconstrictor drugs increases the risk of side effects.
Overdose
with a significant overdose or ingestion, constriction of the pupils, nausea, vomiting, cyanosis, increased body temperature, tachycardia, arrhythmia, collapse, cardiac depression, arterial hypertension, pulmonary edema, and respiratory disorders may be observed.
Storage conditions
- keep away from children
Information provided
1 ml of the drug contains:
Active substance:
Excipients:
special instructions
Long-term use and overdose of the drug should be avoided.
Long-term or frequent use of vasoconstrictor drugs leads to a decrease in the effectiveness of the drug, and their improper use can cause atrophy and swelling of the nasal mucous membranes.
When prescribing oxymetazoline for the treatment of chronic rhinitis, in order to avoid the risk of atrophy of the nasal mucosa, it should be used only under medical supervision
With frequent use of high dosages of imidazoline derivatives, they can lead to reactive congestion (stuffiness) of the nasal passages. Therefore, the drug is used no more than 5-7 days after the start of treatment.
In the following cases, the drug can be used only after a thorough assessment of the risks and benefits of its use:
- patients being treated with monoamine oxidase inhibitors (MAO inhibitors) and other drugs that have the potential to increase blood pressure
- increased intraocular pressure, especially angle-closure glaucoma
- severe cardiovascular disease (eg, coronary disease, hypertension)
- pheochromocytoma
- metabolic disorders (eg, hyperthyroidism, diabetes)
Pregnancy and lactation
Data obtained from a limited number of women receiving this drug during the first trimester of pregnancy did not indicate the development of any adverse reactions due to oxymetazoline that could affect the pregnancy or the health of the fetus/newborn. When used during pregnancy or breastfeeding, do not exceed the recommended dosage.
Features of the effect of the drug on the ability to drive a vehicle or potentially dangerous mechanisms
After long-term use of Nazivin®, in dosages exceeding the recommended ones, a general effect on the cardiovascular system and central nervous system cannot be excluded. In these cases, the ability to operate a vehicle or equipment may be impaired.
