Pantogam - official instructions for use (in tablet form), what it is prescribed for, areas of application, analogues

Pantogam
is a drug belonging to the class of nootropics.
Pantogam
has neurometabolic, neuroprotective and neurotrophic effects.

Pantogam

Available in the form of syrup, as well as tablets of 0.25 and 0.5 g. In bodybuilding, preference is given to the tablet form of the drug.

Pantogam

improves the brain's resistance to hypoxia and toxic substances, promotes stimulation of anabolic processes in neurons, has a stimulating effect, prevents the occurrence of seizures, increases mental and physical performance, and relieves the feeling of fatigue.

For children

Pantogam for children in the form of tablets is used only upon reaching the age of 3; starting from birth, you can take the drug for children in the form of syrup.
Reviews from doctors about Pantogam tablets, in the treatment of many neurological diseases in children starting from 3 years of age, are positive in 99 cases out of 100. The therapy is highly effective with minimal side effects. It is worth noting that the effect of the drug does not occur immediately, but most often, 1-1.5 months after the first dose.

Side effects of Pantogam in children are rare and most often consist of drowsiness or sleep disturbance. It is possible that these manifestations depend on the time of taking the drug, which is not recommended to be taken after 4 o’clock in the afternoon.

On user forums dedicated to drugs for the treatment of various childhood neurological pathologies, a large place is discussed about the drug Pantogam for children. Feedback from forum visitors regarding hyperactivity, stuttering, mental and physical impairments, tics, lack of attention, problems with urination, etc. mostly positive.

Let us recall that Pantogam in tablet form does not have a sufficient clinical research base, and is also physically inconvenient for infants to take, which is why Pantogam tablets are not prescribed to children under 3 years of age.

Side effects

The instructions warn about the possibility of developing the following side effects when prescribing Pantogam:

• Allergic reactions: conjunctivitis, rhinitis, skin rashes (these reactions require a reduction in the dose of Pantogam or its complete withdrawal);
• Other: drowsiness or sleep disturbances, noise in the head (these phenomena are usually short-term and do not require cessation of therapy).

Due to the likelihood of drowsiness in the first days of therapy, caution should be exercised when driving a car and performing potentially hazardous types of work.

Newborns

The drug Pantogam for newborns can only be prescribed by an experienced pediatrician, since it is very difficult to independently notice deficiencies in the development of a child at this age.

Speaking about the effectiveness and advisability of prescribing Pantogam for newborns, reviews from parents are quite contradictory. Some are grateful to the doctors for the timely detection of a problem in the development of their own child and note its further full development, others ignored the advice of the pediatrician and also did not feel any pathological changes.

In any case, even when prescribed for no reason, the drug Pantogam syrup has practically no side effects, and in case of real problems, it will certainly help solve them. After all, often the price of taking a medicine on time can be negligible compared to the possible negative consequences of inaction.

Harm and side effects for newborns

In most cases, the described drug is well tolerated, but some patients may experience side effects from its use, namely:

• allergic symptoms (runny nose, conjunctivitis, skin rash, etc.) - if such manifestations are present, the intake is canceled completely;
• reactions of the nervous system (drowsiness, sleep problems, severe agitation of activity, dizziness, noise and pain in the head) - with such symptoms, the dose of the drug is first simply reduced.

An overdose of the drug is possible if the recommendations regarding taking the drug are not followed and is manifested by severe symptoms described in the list of side effects. In such a situation, gastric lavage and symptomatic therapy will be required.

Indications for use

The syrup is intended for oral administration. Indications for its use are the following conditions:

• cerebral palsy of varying severity;
• encephalopathy in children in the first days of life;
• mental retardation of varying severity, including behavioral deviations in children;
• delayed neuropsychic development;
• delayed speech development;
• hyperactivity syndrome with attention deficit;
• neurosis along with enuresis, nervous tics, stuttering;
• decreased concentration and memory impairment due to previous brain diseases and blockage of blood vessels with atherosclerotic plaques;
• schizophrenia as part of complex therapy;
• extrapyramidal disorders due to chorea, Parkinson's disease;
• epilepsy of varying severity as part of complex therapy;
• psycho-emotional stress;
• excessive mental stress in the child;
• neurogenic disorders of urinary function - pollakiuria, frequent false urge to empty the bladder.

The syrup is also prescribed to children as a prophylactic agent to prevent extrapyramidal disorders during long-term use of drugs from the group of antipsychotics.

Mechanism of action of Pantogam

In the practice of a neurologist, there are many patients with a variety of cognitive impairments. In medicine, so-called nootropics are usually used to correct this type of disorder (including speech development), but most of these drugs have unpleasant side effects, which sometimes negate all treatment. A partial solution is Pantogam - this is also a nootropic drug, but it is of a mixed type and has a wide range of effects. The mechanism of operation of the substance is determined by the fact that its structure is based on gamma-aminobutyric acid, which helps strengthen the brain’s ability to resist hypoxia and the negative effects of toxic substances, and also stimulates the formation of neurons. This acid is vital for the brain to organize a number of functions, which determines the aspects of Pantogam’s effect on the body.

Once in the body, the substance is quickly absorbed from the digestive system, and after two days it is completely excreted unchanged in feces and urine. Thus, this drug allows you to influence the nervous system and is used to treat a variety of mental and neurological diseases. Therapy can be carried out either alone with this substance or in combination with other drugs, since no incompatibilities have been established. It is worth noting that the drug can not only interact well with other drugs, but also enhance and prolong the effect of some, for example, novocaine and sulfonamides.

Pantogam syrup, instructions for use

Adult patients are prescribed a single dose of 2.5 ml - 10 ml, the daily dosage is 15 ml - 30 ml.

For children from 0 months, a single dose of 2.5 ml - 5 ml is recommended, the daily dosage is 7.5 ml - 30 ml.

Therapy is carried out for 1 to 4 months, less often up to 6 months. Re-prescribing Pantogam is possible after a break of 3-6 months.

The recommended range of daily doses for children, depending on pathology and age, is:

• from 0 to 12 months – 5 ml – 10 ml;
• up to 3 years – 5 ml – 12.5 ml;
• from 3 to 7 years – 7.5 ml – 15 ml;
• over 7 years old – 10 ml – 20 ml.

Treatment tactics recommend increasing the daily dose over 7–12 days, followed by taking the maximum dose for 15–40 or more days with a gradual dose reduction (7–8 days) until the drug is discontinued . The course of therapy ranges from 30 to 90 days (for the treatment of some diseases up to 6 months or even more).

For combination therapy of epilepsy with parallel administration of anticonvulsants, 7.5 ml - 10 ml per day is prescribed. Treatment lasts for 12 months or more.

For the combined treatment of schizophrenia with the joint use of psychotropic drugs, 5 ml - 30 ml per day is recommended, with a course of treatment from 30 days to 3 months.

When treating neuroleptic syndrome with concomitant extrapyramidal disorders, take a daily dose of the drug of up to 30 ml of syrup. Therapy is carried out over several months.

When treating the consequences of head injury and neuroinfections, a daily dosage of 5 ml to 30 ml is prescribed.

For extrapyramidal hyperkinesis, for the treatment of patients with organic pathologies of the nervous system, a daily dose of syrup from 5 ml to 30 ml is recommended. The course of therapy is up to 4 months or more.

The syrup is taken in order to restore performance during asthenia and excessive stress three times a day in a dose of 2.5 ml - 5 ml.

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Children with urinary disorders are prescribed 2.5 ml - 5 ml, with a daily dose equal to 0.25 ml - 0.5 ml per kilogram of weight. The course of therapy lasts from 30 days to 3 months; for adults, it is recommended to take syrup 2-3 times a day, 5 ml - 10 ml.

When carrying out long-term therapy, parallel administration of drugs with identical effects is not recommended.

Contraindications

• Psycho-emotional overload, decreased physical/mental performance (the purpose of using Pantogam is to improve memory and concentration);
• Akinetic and hyperkinetic extrapyramidal syndrome due to taking antipsychotics (treatment and prevention);
• Extrapyramidal disorders (including Huntington's chorea, Parkinson's disease, hepatolenticular degeneration, myoclonus epilepsy);
• Cognitive impairment due to neurotic disorders and organic brain lesions (including consequences of traumatic brain injury and neuroinfections);
• Neurosis-like conditions with tics, stuttering (mainly clonic), inorganic encopresis and enuresis;
• Cerebrovascular insufficiency due to atherosclerotic changes in cerebral vessels;
• Hyperkinetic disorders, including attention deficit hyperactivity disorder;
• Epilepsy with slowing of mental processes (in combination with anticonvulsants);
• Schizophrenia, accompanied by organic cerebral insufficiency;
• Neurogenic urinary disorders (pollakiuria, enuresis, urgency, imperative urinary incontinence);
• Violations of the psychological status in children, manifested by general mental retardation, specific disorders of motor functions, speech and their combination, the formation of school skills (writing, reading, counting, etc.);
• Mental retardation, including behavioral disorders;
• Various forms of cerebral palsy;
• Perinatal encephalopathy in children from the first days of life.

Absolute:

• Phenylketonuria (for syrup; due to aspartame content);
• Acute severe kidney disease;
• Pregnancy and breastfeeding;
• Hypersensitivity to any component of Pantogam.

Indications for the use of Pantogam tablets for adult patients and children starting from 3 years of age:

• cognitive impairment in neurotic disorders, as well as due to organic brain damage (including traumatic brain injury and the consequences of neuroinfections);
• extrapyramidal pathologies (hepatolenticular degeneration, parkinsonism, myoclonus epilepsy, Huntington's chorea, etc.);
• cerebrovascular insufficiency provoked by atherosclerotic abnormalities in the vascular structure of the brain;
• prevention, as well as treatment of extrapyramidal syndrome (akinetic, hyperkinetic), due to taking antipsychotics;
• epilepsy occurring with inhibition of mental processes (prescribed in combination with anticonvulsant drugs);
• psycho-emotional excessive stress, decreased physical performance and mental activity, in order to improve memory and concentration;
• neurogenic changes in the process of urination (enuresis, frequent urination, urge incontinence, urgency);
• organic cerebral insufficiency in schizophrenia;
• Children over 3 years of age are prescribed Pantogam tablets for perinatal encephalopathy, mental retardation of varying severity, delayed motor, speech, mental development, or a combination thereof. Also for various forms of cerebral palsy, neurosis-like pathologies (tics, stuttering), hyperkinetic manifestations (hyperactivity syndrome with observed attention deficit).

Indications for use of Pantogam for children from birth, in the form of syrup:

• perinatal encephalopathy (prescribed from birth);
• Cerebral palsy of varying severity;
• mental retardation of varying severity, including behavioral disorders;
• pathologies of psychological status (delayed mental or physical development, specific pathologies of motor functions, speech, as well as their combination);
• development of school skills in children (writing, reading, counting, etc.);
• senile dementia in its initial forms;
• hyperkinetic abnormalities, including attention deficit hyperactivity disorder;
• decreased mnestic-intellectual activity due to arteriosclerotic pathologies of cerebral vessels;
• trauma, toxic or neuroinfectious effects on the brain;
• neurosis-like conditions (stuttering, inorganic encopresis, tics);
• cerebral organic pathology in schizophrenia (in combination with psychotropic drugs);
• extrapyramidal diseases (Parkinson's disease, Huntington's syndrome, hepatolenticular degeneration, myoclonus epilepsy, etc.);
• therapy and prevention of extrapyramidal syndrome due to taking antipsychotics;
• decreased performance, both physical and mental, psycho-emotional overload, in order to improve memory and concentration;
• epilepsy with inhibition of mental processes and decreased cognitive productivity (in combination with anticonvulsants);
• urinary disorders of neurogenic etiology.

The leaflet for the drug Pantogam indicates the following contraindications to its use.

For the syrup:

• first trimester of pregnancy;
• phenylketonuria, due to the content of aspartame in the syrup.

Are common:

• hypersensitivity to hopantenic acid or other ingredients of the syrup or tablets;
• acute kidney pathologies in severe form.

Pantogam tablets, instructions for use

The recommended single dose of Pantogam in the form of tablets for adult patients is 250 mg - 1000 mg, the daily dosage is 1500 mg - 3000 mg.

Children from 3 years of age are prescribed tablets in a single dose ranging from 250 mg to 500 mg, the daily dosage is 750 mg - 3000 mg.

The course of therapy usually takes from 30 to 120 days, in some cases up to six months. After a 3 or 6 month break, you can repeat the course of treatment.

For combination therapy of epilepsy, Pantogam is prescribed in a daily dose of 750 mg - 1000 mg, for a year or more.

In the combined treatment of extrapyramidal neuroleptic syndrome, up to 3 g of the drug is taken over several months.

When conducting combination therapy of extrapyramidal hyperkinesis in patients with hereditary pathological conditions of the nervous system, a daily dose of 500 mg to 3000 mg is recommended for up to 4 months or even more.

To neutralize the consequences of head injury and neuroinfections - 0.25 g (250 mg) of Pantogam, taken 3 - 4 times a day.

To restore performance in conditions of asthenia and excessive stress - 3 times a day, 250 mg.

For the treatment of extrapyramidal syndrome, due to the use of antipsychotics, it is recommended for adult patients 500 mg - 1000 mg, three times a day; for children, the recommended dosage is from 250 mg to 500 mg in 3-4 doses. Treatment lasts from 1 to 3 months.

Children with tics are prescribed 3-6 doses per day at a dose of 250 mg to 500 mg, for 1 to 4 months.

For problems with urination, adult patients take Pantogam tablets 2-3 times a day, 500 mg - 1000 mg; pediatric patients: 250 mg - 500 mg (the recommended daily dose varies from 25 mg to 50 mg per kilogram of weight). The course of therapy is carried out over 1 to 3 months.

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Depending on age, children with various diseases of the nervous system are prescribed from 1 to 3 g of Pantogam.

The dosage regimen most often boils down to increasing the dose over 7–12 days, followed by taking the maximum dose of Pantogam for 15–40 days, with a slow decrease in the maximum dose (7–8 days) until the drug is completely discontinued.

If a repeated course of therapy is necessary, the break should be from 1 to 3 months.

Release form and composition

• Tablets 250 mg and 500 mg.
• Capsules 200 mg and 300 mg Pantogam Active.
• Syrup 10%.

INN (international nonproprietary name) is hopantenic acid.

Pantogam syrup

Substance content in 1 ml:

• Active: 100 mg calcium hopantenate (pantogam).
• Auxiliary ingredients: glycerol, sorbitol, citric acid monohydrate, E 211, aspartame, Cherry flavor, water.

The medicine is in the form of an uncolored or slightly yellowish solution that smells like cherry. Packaged in 100 ml bottles made of light-protective material. In a cardboard box - 1 container, measuring spoon, annotation to Pantogam.

Pantogam tablets

Contents of components in 1 tablet:

• Active: 250 or 500 mg calcium hopantenate (Pantogam).
• Additional: potato starch, E 572, E 504.

The medicine is in the form of white flat pills with a break line and a bevel. Packaged in PVC blister packs of 10 pieces or in dark plastic jars with a lid of 50 pieces. In a cardboard box - 5 packages or 1 jar, accompanying instructions.

Pantogam capsules

Contents of components in 1 capsule:

• Active: 200 or 300 mg of hopantenic acid.
• Additional: TsMK, E 572

Shell components: gelatin, glycerin, E218, sodium lauryl sulfate, water, E 171, dyes.

The medicine is in the form of white (300 mg) and yellow (200 mg) gelatin capsules. Filling: white or yellowish powder. Packaged in blisters of 10 pieces. In a cardboard pack - from 2 to 6 packs, manual.

Storage conditions

It is recommended to store the syrup out of the reach of children in a cool, dark place. The optimal storage temperature should not exceed 25 degrees. After opening the bottle, the medicine should be kept in the refrigerator for no longer than 6 months, after which it should be disposed of, even if the medicine has not yet run out.

The shelf life of the medicine in syrup form is 2 years from the date of manufacture and is indicated on the packaging. After this period, the drug cannot be taken orally.

Analogs

Structural analogues of the active substance:

1. Gopantam;
2. Hopantenic acid;
3. Calcium salt of hopantenic acid;
4. Calcium hopantenate;
5. Pantocalcin.

When choosing analogues, it is important to understand that the instructions for use of Pantogam, the price and reviews of drugs with similar effects do not apply. It is important to consult a doctor and not change the drug yourself.

Which is better: Pantogam or Pantocalcin?

In fact, Pantogam and Pantocalcin are synonyms, that is, their active ingredient is the same substance. Judging by the reviews of experts, the effectiveness and cost of these drugs are almost identical. In this regard, the interchangeability of these drugs is possible.

Reviews about pantogam

Pantogam tablets, for the treatment of various neurological disorders indicated in the instructions for use, receive positive reviews from doctors who use them in their practice. When taken by adults, reviews of Pantogam indicate excellent results of the therapy. 98% of patients are absolutely satisfied with the outcome of the treatment and are ready to trust this drug in the future.

When taken by children, reviews of Pantogam are no less positive, including reviews of tablets when taken by children from 3 years of age, as well as reviews of Pantogam syrup for children starting from 0 months.

For infants, reviews of Pantogam are more varied and do not come to a clear opinion. The thing is that many parents do not trust their pediatricians and often do not follow their recommendations, preferring self-medication and the “natural” development of the child. It is worth noting that often they are really right and the normal development of the baby takes place without any medications.

Only an experienced and respectable pediatrician can give infants the correct diagnosis and provide adequate treatment. One way or another, you make the decision to conduct any treatment for your child, so approach this with all responsibility, taking into account the opinions of several doctors and your own intuition.

Composition of the drug

The active ingredient in both tablet form and syrup is the calcium salt of hopantenic acid (pantogam), but in different dosages. The main component of the drug in its pure form is a white powder consisting of small crystals that easily dissolve in water. The substance has an effect on the human nervous system, stimulates it, thereby increasing performance, activating mental activity, regulating behavior and exhibiting anticonvulsant activity. The drug has the unique property of having a moderate sedative effect and having a stimulating effect on the body.

Auxiliary components, although they do not have a clear effect on the body, can be important if the body has an individual intolerance to one or another component. The additional composition of the tablet form includes: calcium stearate, magnesium hydroxycarbonate and methylcellulose.

As for the syrup, the concentration of the active ingredient in it is 500 mg per dose (to determine it, use a measuring spoon from the kit equal to 5 ml). The big advantage of the liquid form is that it is easier and more pleasant for children to take, as there is a pleasant taste and aroma of cherry. Additional ingredients include: citric acid, sorbitol, glycerol, sodium benzoate, aspartame and purified water.

Instructions for Pantogam: dosage.

The drug can be given to infants in the first days of life, but strictly as directed by the doctor and in compliance with age standards.

• 1 month - 1 year you can give 5-10 ml;
• up to three years - 5-12 ml;
• from 4 to 7 years old - 7-14 ml;
• after 8 years 11-20 ml.

The drug should be taken half an hour after meals, 2 times a day. It is important to give Pantogam before 3 pm, as in the evening it can lead to sleep disturbances in the baby.

The syrup is prescribed for a course of at least 1 month, for the treatment of most diseases - for 50-90 days.

Admission rules:

During the first 10-12 days, we gradually increase the amount of the drug, then take the maximum recommended dose for 1 month.

After this, we carefully reduce the dosage for 7 days until we stop taking it.

Price.

Pantogam syrup for children is relatively expensive - one bottle is not enough for a course, and its cost is approximately 350-400 rubles for 2020.

By the way, the drug is available without a prescription, but this does not mean that you can prescribe it without permission.

The shelf life is 2 years, but after opening the bottle must be stored in the refrigerator.

Analogues of Pantogam and their price.

For children, this drug is the drug of choice, but pharmacies also have similar effects that are often prescribed to adults:

• Gopantam - 250 rubles;
• Calcium hopantenate - 250 rubles;
• Pantocalcin 420 rubles.

Pantogam - review after 2 months of use.

Despite the fact that the product is quite good and popular according to doctors, in our case I did not see a significant effect. Maybe because there was no problem as such, or maybe just time helped.

Many neurological problems in children go away over time, and the established tone of the upper extremities, for example, may disappear after a couple of months and not be noticeable.

However, all problems cannot be solved on their own, and it is important to monitor the child and his development!

Disturbances occurring in the functioning of the brain are diagnosed in newborns. The causes of such pathologies are different: infections, hypoxia during pregnancy or during childbirth, trauma, hereditary predisposition.

Such violations cannot be ignored, as in the future this can negatively affect the physical development of the baby and his mental characteristics. As a means of therapy in such situations, drugs are used to improve the functioning of blood vessels and brain cells. One of them is Pantogam.

Composition, instructions for using Pantogam syrup for children, how much this drug costs, reviews from parents - you will find out all the details by reading our article.

Interaction

Please note that Pantogam:

• Prevents side effects of carbamazepine, phenobarbital, antipsychotics;
• Prolongs the effect of barbiturates;
• Potentiates the effect of local anesthetics (procaine);
• Enhances the effects of anticonvulsants.

Etidronic acid and glycine enhance the effect of the calcium salt of hopantenic acid.

Pantogam, when taken in combination with barbiturates, prolongs their action.

When used together with anticonvulsants, it enhances their effectiveness.

Prevents the side effects of Carbamazepine, Phenobarbital, and neuroleptics.

Potentiates the effects of drugs for local anesthesia (Procaine).

The effect of Pantogam is enhanced by complex treatment with etidronic acid and Glycine.

special instructions

The medicine in syrup form can be used to treat children from the first days of life according to indications and doctor’s prescription. Self-medication can pose a threat to the child’s health, so it is recommended to take the drug only with the permission of a pediatrician or pediatric neurologist. The syrup is not recommended to be taken simultaneously with sorbents and antacid drugs, since this drug interaction leads to a decrease in the absorption of the drug into the general bloodstream and a decrease in its therapeutic effect. If a child takes any medications on a regular basis, be sure to inform the doctor about this.

Manufacturer: Pantogam and drug analogues

Pantogam was invented and produced in Russia. The manufacturer of the medicine is always indicated on the packaging:

• LLC "PIK-PHARMA PRO" - tablets and syrup;
• LLC "VIPS-MED" - only syrup.

The price of both dosage forms is approximately the same - they can be purchased for 350-400 rubles.

If the pharmacy does not have Pantogam, you can buy another drug with the same active ingredient.

Brief overview of analogues:

• Gopantam (about 300 rubles) - only in the form of tablets of 250 and 500 mg. It also has an analgesic effect.
• Calcium gopantheonate (200-250 rubles) - only in the form of 250 mg tablets. The drug is contraindicated in children under 3 years of age.
• Pantocalcin. Tablets 250 mg - about 450 rubles. 500 mg - 600-700 rubles. The description of side effects does not include sleep disturbances, drowsiness or noise in the head.

Synonym of Pantogam - Pantocalcin.