Why is Akriderm prescribed? Instructions, reviews and analogues, price in pharmacies

Pharmacological action of Akriderm GK

In accordance with the instructions for Akriderm GK, the active ingredients of the drug are betamethasone dipropionate, clotrimazole, gentamicin sulfate. The auxiliary substances included in the Akriderm GK ointment are isopropyl myristate, petroleum jelly, propyl parahydroxybenzoate, and petroleum jelly. The auxiliary components in the Akriderm GK cream are sodium dihydrogen phosphate dihydrate, Trilon B, macrogol cetostearyl ether, cetostearyl alcohol, medical vaseline oil, propylene glycol, petroleum jelly.

Betamethasone dipropionate has antiallergic, antipruritic and antiexudative effects. The substance blunts the accumulation of leukocytes, inhibits the process of release of inflammatory mediators and lysosomal enzymes directly at the lesion site, reduces phagocytosis and vascular tissue permeability, and prevents the formation of inflammatory edema.

The effect of clotrimazole, which is part of Akriderm GK, is due to a disruption in the synthesis of ergosterol, which is part of the cell membranes of fungi. The substance is active against Malassezia furfur, Candida albicans, Microsporum canis, Epidermophyton floccosum, Trichophyton mentagrophytes, Trichophyton rubrum.

Gentamicin is an aminoglycoside antibiotic that has bactericidal properties. Shows activity against sensitive strains of alpha- and beta-hemolytic group A streptococcus, as well as coagulase-positive and coagulase-negative strains producing penicillinase.

According to the instructions for Akriderm GK, when the drug is used in therapeutic doses, a slight absorption of its active components into the blood plasma occurs, which depends on the condition of the epidermal barrier of the patient’s skin.

Release form and composition

There are several types of Akriderm, which differ not only due to the small mark at the end of the name, but also due to specific properties.

The usual type, GENTA and GK are available in the form of a cream for external use. Available in 15 or 30 g. The color of the emulsion is white, the presence of foreign contaminants is not allowed.

Akriderm - ointment for external use 0.05%

Akriderm SK is an ointment, the product is also available in 15 or 30 g. The contents have a shade from white to yellow.

The main active ingredient is betamethasone dipropionate. Its consistency in all dosage forms is the same - 0.64 mg/1 g. Standard Akriderm contains nilagin, characteristic of all drugs in this series, purified water, paraffin and petroleum jelly, as well as sodium sulfite.

Variations of GENTA and GK additionally include gentamicin sulfate (1 mg/1 g), cetostearyl alcohol, propylene glycol. However, the first form contains potassium phosphate, and the second contains clotrimazole (along with betameson dipropionate).

Akriderm SK contains salicylic acid, petrolatum and petroleum jelly.

Many people are interested in whether this is a hormonal ointment or not. Yes, the drug belongs to the hormonal category, which discourages some patients from purchasing it, although doctors themselves often recommend this particular medicine.

Methods of use of Akriderm GK and dosage

Akriderm GK cream and ointment should be applied in a thin layer, lightly rubbing it into the affected areas of the skin 2 times a day, preferably in the morning and evening. In mild cases and in the absence of complications, it is possible to use the product once a day.

The duration of treatment is determined individually for each patient and depends on the severity of the disease and its nosological form. As a rule, the maximum duration of therapy with Akriderm GK ointment/cream is 4 weeks. If there is no therapeutic effect, you must consult a doctor to clarify the diagnosis and adjust the treatment regimen.

special instructions

The appearance of signs of hypersensitivity, itching and irritation of the skin during treatment requires stopping the use of this remedy and choosing a more suitable treatment for the patient.

Long-term therapy, application of the drug in large quantities to a large surface of the skin, the use of occlusive dressings and treatment of children can cause systemic absorption of GCS.

Treatment of children must be carried out strictly according to the indications and prescription of the doctor, which will allow monitoring the possible development of systemic undesirable effects. It is possible that the full functioning of the hypothalamic-pituitary-adrenal system is suppressed, symptoms of hypercortisolism appear, a decrease in the excretion of growth hormone, and an increase in intracranial pressure.

Side effects occur especially often when the drug is applied to the skin of the face. Therefore, the therapeutic course should not be longer than 5 days.

The use of Akriderm in ophthalmology is not allowed. It is necessary to avoid getting it into the eyes and mucous membranes.

If treatment with the drug has been carried out for a long time, gradual withdrawal of therapy is recommended.

Side effects of Akriderm GK

According to reviews, Akriderm GK causes virtually no adverse reactions from the body. Individually, local side effects may occur in the form of dry skin, itching, hypertrichosis, steroid acne, irritation, burning, hypopigmentation, folliculitis.

With long-term therapy with Akriderm GK, according to reviews, systemic side effects are possible, which include:

• Increased arousal;
• Exacerbation of hidden foci of infection;
• Ulceration of the mucous membrane of the gastrointestinal tract;
• Insomnia;
• Osteoporosis;
• Dysmenorrhea;
• Hyperglycemia;
• Edema;
• Increase in body weight;
• Increased blood pressure.

When using occlusive dressings with Akriderm GK, the risk of developing systemic side effects significantly increases.

According to reviews, Akriderm GK in children can cause the development of Cushing's syndrome, glucosuria and reversible dysfunction of the adrenal cortex.

Side effects

Akriderm can cause negative signs, especially with long-term use, most often recorded:

• Burning, itching, dry skin, the presence of steroid acne, folliculitis, increased pigmentation, some manifestations of allergies.
• Weight fluctuations, blood pressure fluctuations, swelling, development of osteoporosis.
• Disorders of the digestive tract.
• Increased excitability, sleep problems.
• Exacerbation of infectious pathologies.
• When applying dressings, skin atrophy, symptoms of prickly heat, maceration, and increased infection may occur.

Contraindications to the use of Akriderm GK

The instructions for Akriderm GK indicate that absolute contraindications to the drug are:

• Skin manifestations of syphilis;
• Lupus;
• Chicken pox;
• Skin post-vaccination reactions;
• Herpes simplex;
• Open wound surfaces;
• Hypersensitivity to the components of the product;
• Perforation of the eardrum that occurred during therapy for otitis externa;
• Children's age up to 1 year (for cream), up to 2 years (for ointment);
• Lactation period.

Akriderm GK should be used with caution during pregnancy, as well as in children and adolescents aged 2 to 18 years.

Use during pregnancy and lactation

During pregnancy (especially in the first trimester), the use of the drug is allowed only in cases where the expected benefit to the mother outweighs the potential risk to the fetus. In such cases, the use of the drug should be short-term and limited to small areas of the skin.

It is not known whether the components of the drug are excreted in breast milk. Therefore, if it is necessary to use the drug Akriderm GK during lactation, breastfeeding should be stopped.

Analogs

In pharmacies you can find an analogue of Akriderm GK. There are medications that contain the same active substances and have identical effects. Complete drug substitutes:

• Triderm. The Belgian external product has a high price, which starts from 700 rubles. It has a wide spectrum of action and is available with a doctor's prescription.
• Kanison plus. It has antiallergic, antimycotic and bactericidal effects. Price - about 380 rubles. Produced by an Indian pharmaceutical company.
• Candiderm. Country of origin: India. Indications for use of the cream are the same as for Akriderm GK. Cost - from 270 rubles.

There are medications with differences in composition that can be replaced with the drug on the recommendation of a dermatologist.

1. Celestoderm-B with garamycin. It contains betamethasone and gentamicin. The external remedy is effective against dermatitis and inflammatory processes. Since the composition does not contain clotrimazole, it is not prescribed for the treatment of dermatomycosis.
2. Akriderm SK. The composition contains betamethasone and salicylic acid. The ointment eliminates inflammation, swelling, itching, exfoliates dead skin particles and softens. The product is effective for allergic rashes and rough skin.
3. Advantan. The ointment and cream contain methylprednisolone aceponate, which belongs to the group of corticosteroids and has anti-inflammatory and antipruritic effects.

All these drugs have contraindications and cause adverse reactions, so the decision to replace them should only be made by a doctor.

Akriderm SK

This version of the ointment contains betamethasone, the second active substance is salicylic acid. This composition helps to determine what Akriderm SK ointment treats. The peculiarity of this ointment is that, unlike the previous ones, it helps not only to fight allergic reactions and severe inflammation, its use is justified for hyperkeratosis. Therefore, this drug helps with the same thing that Akriderm ointment helps with (betamethasone, which contains the active ingredient), and also helps soften the skin and speed up the exfoliation of the skin. Used for diseases such as lichen planus, ichthyosis, eczema, psoriasis, ichthyosoform changes.

What do the reviews say?

Some users report that when they used this remedy for the first time, it helped eliminate the symptoms of the disease quite quickly. The next time the drug was used, longer treatment was required and the effect was less durable.

Sometimes Akriderm is used for acne and a similar situation is noted. At first, the rashes go away quickly, but then they come back again and this happens much more often. Moreover, the appearance of pigmented and light areas and deterioration of the skin structure are noted. Although such users do not even know exactly how to use Akriderm ointment, what it helps with and how long to apply it.

By the way, such cases are described quite often. This happens because this drug is not able to influence the causes of the development of dermatitis, relieving the manifestations of the disease. Therefore, the use of Akriderm can only bring temporary relief, and then the development of complications.

Cream "Akriderm"

There are several varieties of this drug, one of them is a drug called “Akriderm”. The drug is produced in the form of an ointment or cream, it all depends on what effect the patient wants to get and what disease needs to be eliminated. The active component is betamethasone, which is present in the ointment in an amount of 0.05%. If you purchase a cream, then it is possible to buy a drug with a concentration of 0.064% or 0.05%.

The medicine allows you to quickly eliminate the inflammatory process and swelling that appears at the site of the lesion. Itching and other allergic skin reactions are eliminated. It is advisable to use the drug for a short time, despite what Akriderm ointment helps with, after a few days it is better to switch to other medications. Such treatment can be considered more of an emergency drug and can be used in really difficult situations.

Akriderm ointment: instructions for use

Akriderm ointment for children and adults

Available in 15 and 30 g tubes. Used in children from 1 year and adults. This form of release is used for chronic diseases, because it has a high penetrating ability and softens the skin when it thickens, which often happens with complications after illnesses. After prolonged use or after application under a bandage, it can be absorbed into the bloodstream and have a systemic effect. That is why Akriderm ointment is indicated for use after a doctor’s prescription.

Pharmacological properties

Akriderm has antifungal and antibacterial activity

Betamethasone reduces the rate of production of enzymes and inflammatory mediators in the skin, thereby quickly stopping the inflammatory process. This substance has pronounced anti-inflammatory and anti-edematous activity. The drug reduces the production of histamine in the affected area, thereby eliminating itching and flaking of the skin.

The exact mechanism of action and pharmacological properties depend on the detailed composition.

Akriderm GK also has antifungal and antibacterial activity. Akriderm Genta is used for swelling and inflammation of the skin caused by a bacterial infection, since the drug contains an antibiotic.

Akriderm SK additionally has a keratolytic effect due to the inclusion of salicylic acid in the composition. It stimulates the process of cell renewal, eliminates peeling and discomfort in the affected area.

Contraindications

It is forbidden to use the ointment in the treatment of skin pathologies for pregnant women. This is due to the fact that the active substances present in it can cause harm to the fetus. If the severity of the pathology forced the patient to use this medication, then specialists after the birth of the baby should conduct a thorough examination. If the mother was prescribed Akriderm ointment during breastfeeding, then lactation is artificially stopped during therapy.

The drug is not prescribed to patients who have been diagnosed with the following diseases:

• tuberculosis;
• chicken pox;
• violation of the integrity of the skin;
• the body's reaction to the introduction of vaccines.

The use of the medication by children under 2 years of age is also prohibited.