Instructions for use of Andipal, at what pressure the drug is indicated, how to use it correctly

At what pressure is the drug used?

Andipal can only be taken with high blood pressure. The drug does not treat hypotension and does not eliminate the causes of the pathology. The main effect of consuming the drug is a decrease in the intensity of symptoms accompanying high blood pressure. For this reason, Andipal is considered as an emergency drug.

The maximum level at which taking the medication is justified is 160 mmHg. At higher levels, it is not recommended to consume Andipal. This is due to the effect of bendazole in the tablets. The substance first increases blood pressure and then lowers it.

Pharmadynamics and pharmacokinetics

Andipal begins to act 15 minutes after administration. This is due to the fact that the active components of the drug are quickly absorbed into the blood. The condition of a person with high blood pressure is normalized by improving cerebral circulation and stopping the release of adrenaline.

Analgin, entering the body, helps reduce the pain symptoms of migraines. The substance also reduces the severity of swelling in soft tissues, which provokes an increase in body temperature.

Papaverine eliminates spasms of smooth muscles in the digestive organs and in the walls of blood vessels. By dilating the arteries, blood flow improves.

Dibazol reduces heart rate and normalizes breathing. Phenobarbital in the drug has a sedative effect on the cells of the central nervous system.

General description of the drug Andipal

To begin with, let us clarify that Andipal is an antispasmodic drug, the action of which is aimed at eliminating spasms of varying intensity, as well as reducing blood pressure. The composition of Andipal is dominated by such active components as phenobarbital, dibazol, analgin and papaverine. It is the interaction of these substances that forms the sedative properties of the drug, under the direct influence of which the elimination of smooth muscle spasticity is observed, and, consequently, the internal pain syndrome weakens and the blood vessels dilate.

Thus, phenobarbital provides a sedative effect, analgin is an antipyretic component, dibazole and papaverine reduce the tone of the smooth muscles of all organs, causing vasodilation.

Andipal is produced mainly in tablets; in addition, in pharmacology there is its complete analogue in the form of Andipal-B, which not only has identical properties, but also has the same chemical composition. Also known are Benalgin, Kofalgin, Spazgo, Revalgin and others.

Composition and release form

Andipal is available in the form of round tablets of white or yellowish color. There are distinctive marks on the surface of the tablets. At the pharmacy, the drug is sold in cardboard or paper packages containing 10 tablets of the drug.

1 pill contains the following active ingredients:

• analgin – 0.25g;
• dibazol – 0.02 g;
• papaverine – 0.02 g;
• Phenobarbital – 0.02 g.

Among the auxiliary components of the medication are:

• potato starch – 47.7 mg;
• talc – 9.25 mg;
• stearic acid – 2.9 mg.

Analogs

This product has no analogues in composition. However, you can buy an effective medicine at the pharmacy that is similar in properties to this drug. The following drugs are analogues of Andipal for their antispasmodic effect:

• Nomigren;
• Urolesan;
• Papazol-UBF;
• Unispaz;
• No-shpalgin;
• Theodibaverin.

Indications for use

The tablets are sold in pharmacies without a doctor's prescription. Indications for taking the medicine:

• hyperthermia accompanied by an inflammatory process;
• increased blood pressure;
• vegetative-vascular dystonia;
• spasms of smooth muscles of the gastrointestinal tract;
• circulatory disorders in the brain.

The medicine is prescribed to reduce pain in the postoperative period, during complex diagnostic procedures and with high blood pressure.

Contraindications

In addition to hypotension, Andipal has other contraindications for use:

• blood pathologies – coagulation disorders, anemia;
• all types of glaucoma;
• arrhythmia;
• sensitivity to the components of the drug;
• kidney and liver diseases;
• hereditary disorder of pigment metabolism;
• obstruction of the gastrointestinal tract.

The medicine must not be taken during pregnancy, regardless of trimester. Clinical trials have revealed the harmful effects of the drug's components on the developing fetus. Taking Andipal during gestation threatens to cause deviations in the psychological state of the child - developmental delays, impaired speech functions.

The drug helps with headaches, so patients believe that it can be used to combat hangover. The instructions say that the drug should not be used with alcoholic beverages, since the active substances of Andipal greatly enhance the effect of alcohol on the human body. This can lead to unpredictable consequences.

Price for Andipal

This drug is one of the available medications. The difference in price for Andipal depends on the form of release, the number of tablets in the package, the manufacturer, and the region of sale. In St. Petersburg and Moscow, you can buy it cheaply at a city pharmacy for a special offer or order it through an online store where sales are held with discounts, and delivery by mail.

Blood pressure pills are one of the most popular medications. On pharmacy shelves there are a variety of names that have different effects. Some medications increase blood pressure. Others lead to the opposite result. The variety of names is determined by the need to select components to which the patient does not have hypersensitivity. Andipal for blood pressure is prescribed by doctors quite often; it is one of the new medical developments. These blood pressure pills are intended to return it to normal levels. “Andipal instructions for use, at what pressure to drink?” – after reading this article, you will find out the answer.

Hypertension is a common disease in the modern world. The main reasons are regular stress and strong emotional stress. But low physical activity, increased concentration of salt in food, excessive consumption of alcoholic beverages, and a hereditary tendency also provoke the development of hypertension. The disease manifests itself mainly in the female population after reaching 40 years of age. In men, hypertension develops less frequently (in this case, the main factor leading to hypertension is excessive drinking of alcoholic beverages).

Andipal is a combined drug that has an analgesic, antispasmodic and vasodilator effect on the body.

Andipal for pressure has several effects simultaneously, as it is a combined medicine. It is intended to eliminate spasm of the walls of blood vessels and smooth muscles. Lowers body temperature and has an analgesic effect. Therefore, Andipal avexima is used for a whole range of diseases (elimination of pain in the gastrointestinal tract, migraines, returning the body temperature to optimal levels).

Admission rules

In order to get the maximum effect from the drug, you must adhere to some rules during treatment:

1. Take the drug once when signs of hypotension appear. Take 1-2 tablets at a time.
2. Use the drug for long-term therapy only with the permission of a cardiologist. The duration of therapy does not exceed 10 days
3. Take the drug with food. A tablet taken before meals causes irritation of the mucous membranes of the stomach and intestines.
4. For long-term use, do not take more than 4 tablets per day.

The dosage of the medication may vary depending on the therapeutic goals:

• to relieve headaches, Andipal is taken in 2 doses with an interval of 1 hour;
• for hypertension, drink the drug 2 times a day for 3 days.

In the initial stages of hypertension, Andipal is taken only in extreme cases. Failure to comply with the dosages prescribed by the doctor may lead to the appearance of a collaptoid state.

For blood pressure, the drug is indicated for children from 8 years of age. For hypertension, they are allowed to take 2-3 tablets per day.

Andipal: instructions for use for high blood pressure

At what pressure and how to take Andipal? What does it cure? What does it help with? Will Andipal tablets for blood pressure be effective or not? Answers to such questions are of interest to hypertensive patients who are faced with arterial hypertension.

Today we will look at the action of the analgesic-antispasmodic Andipal, the hypotensive effect of which is successfully used in the fight against hypertension. Although the antihypertensive effect is a side effect of Andipal, this allows the medicine to be used with high systolic and diastolic pressure.

The main active ingredients of the antispasmodic and analgesic Andipal include analgin, papaverine hydrochloride, dibazole and phenobarbital, and auxiliary ingredients include talc, stearic acid and starch.

Pharmaceutical companies produce Andipal in the form of white tablets with a faint yellow tint (or pure white). There are 10 tablets in a contoured cell-free package made of aluminum foil and polyvinyl chloride film (polymer-coated paper). The drug is produced in a polymer jar of 10, 20, 100 pcs.

To understand the pharmacological action of the drug, you need to understand the effects of each component of the analgesic-antispasmodic.

Metamizole sodium (analgin) is intended to relieve analgesia (pain) and provide an anti-inflammatory effect.

Phenobarbital exhibits a hypnotic and sedative effect, suppresses foci of pathological excitation in the cerebral cortex. Its effect on the body is accompanied by an antiepileptic effect and enhanced analgesic components. In combination with the latter, blood flow is normalized and convulsive contractions that appear in the smooth muscle area of ​​the abdominal cavity are eliminated.

Papaverine is considered a powerful antispasmodic, with an affinity for blood vessels and the heart.

Thanks to dibazole, it has a vasoconstrictor effect. This component relaxes smooth muscles, increases immunity, normalizes blood pressure, and relieves antispasmodic pain.

The use of Andipal for high blood pressure is not suitable for all patients who are diagnosed with arterial hypertension. The medicine is prescribed for mild forms of hypertension or at the initial stage.

As a rule, analgesic-antispasmodic tablets help when the pressure has risen due to spasm of blood vessels. If arterial hypertension manifests itself for another reason, then it is not recommended to take Andipal.

When the patient is faced with the initial stage of hypertension, constant use of Andipal tablets is excluded. A specialist can prescribe the drug occasionally or in a short course. Andipal for hypertension reduces blood pressure, calms (mild effect) and relieves headaches.

We have already found out that Andipal is prescribed for the initial stage of hypertension, high blood pressure and spasms of blood vessels. It should also be noted that the analgesic-antispasmodic is used for:

• pain (head, abdomen, pelvis, throat),
• hypertensive heart disease,
• painful urination,
• cholelithiasis,
• disorders of the digestive processes,
• lesions of the trigeminal nerve.

The drug Andipal is recommended for use in case of a short-term increase in blood pressure not exceeding 150-160/90. As a rule, the medication is effective and quickly copes with painful symptoms that can appear along with high blood pressure.

When there is an increase in blood pressure, Andipal is taken once, one or two tablets. As prescribed by the attending physician, the analgesic-spasmolytic can be repeated. The duration of the therapeutic drug course should not exceed more than 10 days. Then a month-long break is taken. Take Andipal orally 10 minutes after meals (liquid and light meals) no more than 3 times a day.

If the increase in blood pressure is caused by external factors, then to achieve a hypotensive effect it is enough to drink one antispasmodic tablet. In case of arterial hypertension, take 3 tablets per day. A stable decrease in blood pressure is observed within 5 days. Since the chronic course of the disease requires longer-term use of medications with a hypotensive effect, Andipal should be replaced with another medicine.

For vegetative-vascular dystonia of the hypertensive type, Andipal is taken one tablet 2 times a day for 3 days. Drug therapy is supplemented with motherwort and valerian extract.

To enhance the hypotensive effect, Andipal is combined with:

• calcium channel blockers (Corinfar, Nifedipine),
• beta-blockers (Metoprolol, Oxprenolol, Anaprilin),
• nitrates (Nitrosorbide, Sustak, Nitroglycerin),
• diuretics (Hypothiazide, Furosemide),
• myotropic antispasmodics (Eufillin, Dipyridamole),
• ganglion blockers (Pentamin),
• antiarrhythmic drugs (Amiodarone).

The drug Andipal is not recommended for use in case of allergic reactions to antispasmodic components, blood diseases, impaired renal and liver function, the first trimester of pregnancy, breastfeeding, increased concentration of porphyrin in the blood, severe angina pectoris, chronic autoimmune diseases, tachyarrhythmia, cardiac conduction disorders, G- deficiency 6-FD, children under 8 years of age, angle-closure glaucoma.

It is not recommended to take Andipal with low blood pressure, since the drug has a hypotensive effect. In case of hypotension, the risks of impaired brain function and disease symptoms increase.

The hypotensive effect of Andipal decreases when taken with:

• tonics (ginseng root, Rhodiola and Eleutherococcus extracts),
• direct-acting adrenergic agonists (Adrenaline, Noradrenaline),
• adrenergic agonists of indirect action (Ephedrine),
• analeptics (Camphor, Bemegride, Lobelin, Sulfocamphocaine, Cordiamin).

The parallel use of Andipal with adsorbents, enveloping and astringent agents negatively affects the process of absorption of the antispasmodic in the gastrointestinal tract. When using the drug with narcotic analgesics, the risk of adverse reactions increases.

Adverse reactions that may occur when taking Andipal include:

• drowsiness,
• impaired renal and liver function,
• hypotension,
• negative impact on the speed of psychomotor reactions.

Less commonly, the patient may experience nausea, allergic reactions, constipation, depression, and ataxia. With long-term use, metamizole sodium can have a depressing effect on the blood in the form of anemia, agranulocytosis and thrombocytopenia.

Since the drug is a potent drug, the dosage of Andipal is prescribed only by a doctor, who must take into account the general condition of the patient, the presence of chronic diseases and contraindications.

What are the symptoms of an overdose of Andipal? If for some reason the patient experiences an overdose of the drug, then headaches, severe drowsiness, nausea and vomiting are observed. Before the arrival of doctors, it is recommended to rinse the stomach and take activated charcoal. Symptomatic therapy is indicated.

Nowadays, pharmaceutical companies produce many analogues of Andipal. Depending on the indications and contraindications, you can choose the product that will become a “lifesaver”, at the same time relying on the composition and price. The fact is that phenobarbital, which is part of Andipal, is classified as a narcotic component that affects the functionality of the brain.

Analogs of Andipal include:

• Teodibaverine, Captopril, Analdim,
• Nomigren, Papazol, Kofalgin,
• Quatrox, Celebrex, Urolesan,
• Unispaz, No-shpalgin.

Marina, 44 years old So it turned out that I have neurocircular dystonia (hypertensive type). It happens that blood pressure rises due to psycho-emotional overload, changes in weather or fatigue. I don’t even resort to using a tonometer, since I immediately determine blood pressure based on the characteristics of the headache. Once they recommended Andipal to me. To be honest, at first I thought that this remedy only relieved headaches. I felt a little uneasy, thoughts flashed through my head about what if Andipal increased the blood pressure and did not lower it. But everything worked out. The use of Andipal for high blood pressure allows you to normalize blood pressure approximately 20-30 minutes after administration. The headache subsides and it immediately becomes easier, because the pressure drops. I did not notice any obvious adverse reactions in my case. Elena, 48 years old, I often experience headaches due to several chronic diseases. Painkillers are always at hand, including Andipal. The latter is excellent for headaches caused by increased blood pressure, unlike Ketonals and Pentalgins. Andipal allows you to reduce blood pressure to a comfortable level in my case of 110/70 (plus or minus), and at the same time exhibits an analgesic effect. It does not act immediately, after 30 minutes. I observe the effect for several hours. I think the downside is the presence of analgin in the drug; I try not to use Andipal tablets for blood pressure too often. Elena, 48 years old Andipal (Avexima) is sometimes taken by the spouse when spasms appear in the brain, migraines, or when blood pressure jumps by 10-20 units. One tablet is enough for him and after about half an hour there is a significant improvement. We do not practice the use of Andipal for high blood pressure, but for a slight increase - even so. The analgesic is in our first aid kit as a backup remedy. The medicine is a good antispasmodic, helping with moderate pain syndromes. However, please note that Andipal is ideal for one-time cases when blood pressure is slightly elevated or you just have a headache. Section: Medicines

Adverse reactions

Therapy with Andipal can cause:

• allergic skin rashes;
• feelings of drowsiness;
• liver dysfunction.

After taking Andipal, it is not recommended to drive a vehicle or perform work that requires increased concentration.

Among the side effects of the drug are:

• blood thinning;
• development of a depressive state;
• depression of the nervous system;
• decreased motor activity.

Due to numerous adverse reactions, Andipal is not recommended for use as a pain reliever. For this purpose, drugs with a milder therapeutic effect are selected.

In case of an overdose of the drug, the following is observed:

• drowsiness;
• dizziness;
• collptoid state.

Interaction with other medications

When Andipal is combined with other synthetic drugs, an increased hypotensive effect may be observed. Such means include:

• nitrates – Nitrosorbit, Monosan, Dinisorb;
• myotropic antispasmodics – Drotaverine, Nosh-pa, Papaverine;
• diuretics – Veroshpiron, Furosemide, Uregit;
• beta blockers - Nebivolol, Penbutolol, Anaprilin.
• Ganglioblockers – Gigroniy, Pentamin.

If Andipal is used in conjunction with other non-narcotic drugs, the toxic effect on the body may be increased. It is not recommended to take the drug with sorbents, as they reduce the level of absorption of the active components into the gastrointestinal tract. The shelf life of the drug is 2.5 years.

Patient reviews

Alexander 34 years old . “The drug is well suited for slightly elevated blood pressure, but for people whose blood pressure rises to 200 mm Hg. he won't help. The product saves me from headaches and nausea that occurs after overwork or drinking coffee. I recommend that people who are taking medicine for the first time consult a doctor. The undeniable advantage of the medicine is its cost.”

Stanislav is 54 years old . “I took Andipal in the initial stages of the development of hypertension, when the pressure rose to 140-160 mm Hg. Art. Over time, the drug stopped helping, since the tablets only slightly lower blood pressure and are addictive if used frequently. I believe that the medicine is suitable for young people who do not suffer from chronic hypertension. For people with gastrointestinal diseases, it is better to give preference to other medications, since Andipal negatively affects the mucous membranes of the intestines and stomach.”

Elena is 41 years old . “My parents have been drinking Andipal since 2010. Recently, the drug has stopped helping due to the fact that addiction to its components has occurred. During treatment, parents noted a side effect – nausea.”

Svetlana, 36 years old . “I had to take Andipal while on vacation. After drinking whiskey I had a severe headache. I drank the drug at risk to my health, since the medicine is not compatible with alcohol. Fortunately, there were no adverse reactions. I advise anyone who is planning to undergo a course of medication to consult a doctor first. This medicine has many side effects."

Tatyana, 38 years old . To take the drug as an antipyretic or analgesic, it is necessary to control the blood pressure level. The product is not suitable for people suffering from low blood pressure. These tablets help me with hypertension associated with changing weather or stress. Among the main advantages I can note the low cost. The only drawback of the product is the lack of instructions for use.

During pregnancy and lactation

The instructions for use of Andipal contain clear instructions prohibiting the use of the drug in the first trimester and during breastfeeding. If the composition is necessary for certain clinical manifestations, then its administration should be under the strict supervision of a physician after laboratory studies of the condition of the liver tissue and the picture of peripheral circulation.

Hypertension is a disease that borders between life and death. Not only the state of health, but also the number of years lived depends on correctly selected medications and their optimal dosages.

After examining and determining the cause of hypertension, the doctor may prescribe:

• Triampur compositum has hypotensive and diuretic action;
• Minoxidil;
• Verapamil;
• Atenolol;
• Clonidine;
• Enam.

Analogs of Andipal with similar antispasmodic properties:

The patient undergoes tests to determine the level of magnesium, creatine and potassium in the blood. At the same time, concomitant diseases are treated and prevented.

Andipal is not universal and patients tolerate its effects differently. If the duration of therapy is exceeded, even cases of addiction may develop. But most of those who took the drug speak of it as a life-saving composition that helped with momentary surges in blood pressure, spasms and headaches. But we must not forget that it is only part of symptomatic, but not etiotropic treatment, that is, it improves well-being, but does not eliminate the problem of hypertension . Attracts with its accessibility. A pack of 10 tablets costs about 35 rubles.

Doctor's recommendations online

When taking Andipal for blood pressure, a rapid therapeutic effect is observed. Its effectiveness is evidenced by reviews from patients suffering from hypertension. Before using the product, you must ensure that there are no contraindications. If you take the medicine for hypotension or to relieve a hangover, you can get negative consequences in the form of nausea, weakness and an allergic reaction. The medication is suitable for one-time or short-term use. For course treatment, Andipal is taken only with the consent of the doctor, since it affects the composition of the blood and is addictive.