Contraindications
There are a number of conditions, the presence of which in a patient obliges the doctor to refrain from prescribing the specified medication to the patient; these include for Reamberin:
- acute renal failure;
- period of bearing a child;
- recent traumatic brain injury with associated cerebral edema;
- kidney disorders of chronic etiology;
- special individual hypersensitivity to any of the components of the product;
- lactation period.
In case of renal failure and alkalosis, Reamberin should be used with great caution.
Reamberin is used in adults and children from 1 year of age as an antihypoxic and detoxifying agent for acute endogenous and exogenous intoxications of various etiologies.
Contraindications to the use of the drug Reamberin are: individual intolerance, a condition after a traumatic brain injury, accompanied by cerebral edema, acute renal failure, chronic kidney disease (stage 5, glomerular filtration rate less than 15 ml/min), pregnancy, during breastfeeding.
With caution: with alkalosis, renal failure.
Used in adults and children from 1 year of age as an antihypoxic and detoxifying agent for acute endogenous and exogenous intoxications of various etiologies.
individual intolerance;
condition after a traumatic brain injury, accompanied by cerebral edema;
severe renal dysfunction;
pregnancy;
lactation period.
With caution: alkalosis.
Despite the general beneficial effects of the main components, the drug should not be used for cerebral edema or in case of individual intolerance to the main components.
Side effects are as follows:
- Allergic reaction.
- Metallic taste.
- The appearance of redness of the skin.
When the first signs of side effects appear, you should stop administering the drug.
What does Reamberin help with?
The dropper is recommended for adults and children over 1 year of age as an antihypoxic agent and detoxifier for acute internal and external poisoning of the body with toxic substances:
- skin lesions (psoriasis, various progressive dermatitis, dermatoses) - people with dermatological problems are recommended to undergo a two-week course of therapy every 3 to 4 months;
- severe blood loss, acute bleeding due to circulatory disorders in organs and tissues, sepsis;
- heart attack, stroke and other cardiac emergencies;
- disturbance of gas exchange in the lungs;
- oxygen starvation of brain tissue;
- liver dysfunctions - icteric syndrome, hepatitis and hepatosis, liver cirrhosis, cholestasis, liver failure;
- oncopathology with sites of stasis, as well as after chemotherapy and radiation therapy.
Also, droppers with Reamberin are indicated for severe overdose of alcohol and drugs, a shock reaction against the background of predisposing factors, during preparation for operations, for emergency treatment after surgical interventions and for patients with severe exhaustion of the body. Moreover, the effect of the medicine is noticeable under constant stress and at the stage of adaptation of the body of people who are professionally involved in sports.
Reamberin - reviews of the drug
The medicine is primarily intended to cleanse the drug of toxic substances, and, as a result, slow down the division of pathological cells. Let's move on to reviews from forums about Reamberin as a remedy for psoriasis, why and why it was prescribed to patients, and about the effectiveness of the medicine:
Evgenia, 29 years old, Nizhny Novgorod
I have had psoriasis for a long time. Doctors prescribed a lot of different remedies. At first they helped, but soon their effectiveness began to decline. The attending physician prescribed Reamberin. The solution must be administered intravenously, this caused me inconvenience, since visiting the hospital every day is difficult for me. But the therapy did not last long, about a week. What can I say? Yes, the product relieved my symptoms. Every day the improvements were more and more noticeable. Three months have passed and still no relapse. I hope he doesn't show up for at least another six months.
Alina, 34 years old, Chelyabinsk
I have suffered from psoriasis for several years. Recently, severe complications appeared, the disease spread rapidly, and I had to visit a doctor. Before that I only used ointments for psoriasis. The doctor, of course, immediately said that I should have contacted him earlier. He prescribed a course of therapy with Reamberin, since, as it turned out, I had a severe stage of psoriasis. The symptoms of the disease have passed, but first of all I advise everyone to see a doctor, and then begin treatment.
Directions for use and doses
IV, drip.
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Adults: at a rate of up to 90 drops/min (1–4.5 ml/min) – 400–800 ml/day. The rate of drug administration and dosage are determined in accordance with the severity of the patient's disease.
Children: at the rate of 6–10 ml/kg daily, once a day at a rate of 3–4 ml/min, but not more than 400 ml/day.
The course of drug administration is up to 11 days.
Adults: Reamberin is administered intravenously at a rate of 1–4.5 ml/min (up to 90 drops per minute). The average daily dose is 10 ml/kg. The course of therapy is up to 11 days.
Children: administered intravenously at a rate of 6–10 ml/kg per day at a rate of 3–4 ml/min. The course of therapy is up to 11 days.
Instructions for use
To eliminate the possibility of problems, you must follow the recommendations for use.
They are as follows:
- The dosage and rate of administration are determined individually. The choice depends on the condition of the body, as well as weight, and the introduction of other compounds. Therefore, the course is prescribed by a qualified doctor.
- For adults, the maximum daily dose is 2 liters. Large amounts can result in high concentrations of essential elements.
- The maximum injection rate is 90 drops per minute. Adjustment can be made using a dropper.
The doctor prescribes an individual treatment program depending on the condition of the body.
During pregnancy
At the time of pregnancy, such drugs are prescribed in extreme cases. In this case, the doctor must choose the dose and rate of administration depending on the patient’s condition.
The maximum dose is no more than 1 liter. In this case, the delivery speed is reduced to 70 drops per minute. At the time of drug administration, the patient should be under the supervision of a physician.
For children
For newborns and up to one year of age, the maximum daily dose is calculated based on body weight.
Recommendations for use are as follows:
- No more than 5 ml per kg.
- The drug can be administered once a day.
At the age of 1 to 14 years, the dose increases to 10 ml per kg. In this case, the maximum daily dose is 400 ml.
special instructions
Some recommendations for use are prescribed for specific diseases. The fact that the substance is administered by injection determines the need for highly qualified personnel who will carry out the procedure.
To exclude the possibility of serious problems, you should consult your doctor before using the drug.
Pharmacological effects
The active substance protects the heart muscle, nerve cells, liver and kidneys from toxins. It also has antihypoxic, antioxidant and detoxification activity. By inhibiting the reactions of fat peroxidation, during hypoxia and tissue ischemia, enzymes that exhibit antioxidant activity are stimulated.
The membranes of the cells of the brain, kidneys, liver and heart are stabilized. The product also has a diuretic effect.
Sodium N-methylammonium succinate penetrates cell mitochondria and participates in the Krebs Cycle, inhibiting oxidation reactions and increasing intracellular energy potential (creatine phosphate and adenosine triphosphate accumulate).
Penetrating into the body, the drug does not accumulate, but is completely consumed.
Side effects
Rapid administration of the solution may cause the following adverse reactions:
- Cardiovascular system: pain in the heart, shortness of breath, palpitations, tachycardia, chest pain;
- Immune system: anaphylactic shock, angioedema, allergic reactions;
- Skin and subcutaneous tissue: itching, urticaria, allergic rash;
- Vascular disorders: feeling of heat and redness of the upper body (of a short-term nature);
- Gastrointestinal tract: metallic taste in the mouth, vomiting, abdominal pain, nausea, diarrhea;
- Respiratory disorders: dry cough, shortness of breath;
- Nervous system: anxiety, headache, agitation, dizziness, paresthesia, tremor, convulsions;
- Changes at the injection site and general disorders: weakness, sweating, pain at the injection site, chills, hyperthermia, edema, phlebitis, hyperemia.
If side effects occur, it is recommended to reduce the rate of administration of the solution. There is no information about an overdose of the drug.
Overdose
There is no information about cases of overdose. However, there is a possibility of intensifying side effects with long-term treatment with Reamberins in high dosages.
Arterial hypotension may occur, which requires stopping the infusion of the drug Reamberin, and, if necessary, introducing hypertensive drugs, cardiac drugs, calcium chloride, polyglucin.
No cases of overdose have been identified. If the drug is administered incorrectly, side effects from the respiratory, immune, cardiovascular, nervous, digestive, and integumentary systems are observed.
Side effects while taking the medication include (from common to rarely diagnosed complications):
- allergies (swelling, anaphylactic shock, rashes, itching);
- dyspnea;
- frequent yawning;
- feeling of lack of oxygen;
- difficulty breathing;
- dry cough;
- chest pain;
- immune disorders;
- pressure fluctuations;
- increased heart rate;
- burning sensation in the chest;
- redness in the upper parts of the body (a short-term reaction immediately after taking the medicine lasts 5-10 minutes);
- nausea;
- vomit;
- metallic taste;
- stool disorder;
- abdominal pain;
- cephalgia;
- dizziness;
- convulsions;
- tremor;
- hyperexcitability;
- increased anxiety and restlessness;
- hyperhidrosis;
- temperature increase;
- chills;
- general weakness;
- pain at the IV insertion site.
The presence of adverse reactions indicates that the medication was administered too quickly or the dosage was incorrectly selected, or an allergy to the drug. In addition, complications arise due to long-term use of the drug.
If you feel worse, you should consult a doctor. He will adjust the dosage and course of treatment or replace the medicine with an analogue. If you feel unwell immediately during the administration of the medicine, then you need to stop the procedure and, if necessary, carry out symptomatic therapy.
Analogues of Reamberin
Analogs are prescribed for treatment:
- Meglumina sodium succinate;
- Anexat;
- Antaxon;
- Artamin;
- Acizol;
- Bianodine;
- Braidan;
- HepaMerz;
- Gluconeodesis;
- Glutamic acid;
- Dalizol;
- Desferal;
- Dianil;
- Digitalis antidote for BM;
- Zorex;
- Ionostigmine;
- Calciumfolinate Ebewe;
- Calcium folinate;
- Carbactin;
- Carboxim;
- Carbopect;
- Carbosorb;
- Cardioxan;
- Cuprenil;
- Lamisplat;
- Larnamin;
- Levulose;
- Leucovorin calcium;
- Lignin;
- Medetopect;
- Naloxone;
- Naltrexone;
- Sodium thiosulfate
- Ornilatex;
- Ornitsetil;
- Pelixim;
- Pentacin;
- Polyfan;
- Polyphepan;
- Sanitation;
- Sorbex;
- Trekrezan;
- Activated carbon;
- Unithiol;
- Uromitexane;
- Filtrum Sti;
- Ceruloplasmin;
- Extranil;
- Enterodesis;
- Epilapton;
- Etiol.
We invite you to familiarize yourself with Erius Syrup for children instructions for use. Erius syrup
There are no drugs synonymous with Reamberin that are absolutely similar in composition. However, if necessary, the medicine can be replaced with other medications that are similar to the solution in terms of their effect on the body. Analogues of Reamberin include:
- Xylate;
- Sodium chloride;
- Plerigo;
- Bicarbonate of soda;
- Gluxil;
- Lactoxyl;
- Sorbilact;
- Hunyadi Janos;
- Holiver;
- Rhythmcore;
- Enerliv.
Shelf life and storage conditions
The medicine does not lose its properties during 3 years of storage. If necessary, the substance may be frozen at the time of transportation. Like other products, this one should be kept away from children.
Recommended storage conditions are in a dark place, the temperature should be between 0 and 25 degrees Celsius. If a precipitate appears or a color change occurs, do not use the solution.
Reamberin is an almost irreplaceable drug. It can be prescribed in a wide variety of cases and combined with many others. Self-injections are strictly prohibited, since the body’s reaction to active substances is difficult to predict.
In a place protected from light, at a temperature not exceeding 25 °C. Freezing of the drug is allowed. If the color of the solution changes or there is a precipitate, the use of the drug is unacceptable.
Keep out of the reach of children.
Reamberin should be stored in a place protected from light at a temperature of 0 to 25 ° C. Freezing of the drug is allowed.
If the color of the solution changes or there is a precipitate, the use of the drug is unacceptable. Keep out of the reach of children.
Interaction with other drugs
Combines well with antibiotics, water-soluble vitamins, and glucose solution. It is not recommended to mix the drug in a bottle or container with other medications.
Intravenous administration of the drug Reamberin simultaneously with calcium supplements is unacceptable due to possible precipitation of calcium succinate.
In general, the drug Reamberin is well compatible.
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It can be administered simultaneously with a glucose solution or water-soluble vitamins or antibiotics.
Mixing the product with other solutions and medicinal substances is unacceptable.
Also, you should not combine the use of Reamberin with the administration of calcium supplements, since there is a possibility of calcium succinate precipitating.
Price and holiday conditions
| Volume of medicine | Price for Reamberin in rubles |
| 100 ml | from 120 rub. |
| 200 ml | from 150 rub. |
| 250 ml | from 160 rub. |
| 400 ml | from 180 rub. |
| 500 ml | from 190 rub. |
Store in a place protected from light, out of reach of children, at a temperature of 0-25 °C. Freezing the solution is allowed. Shelf life – 5 years.
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On prescription.
Release form and composition
The release form of Reamberin is a 1.5% solution for infusion therapy, in bottles of 200 and 400 ml, polymer containers of 250 and 500 ml.
The active ingredient of the drug is meglumine sodium succinate; 1 liter contains 15 grams.
The auxiliary components of the solution include:
- Sodium chloride – 6 g;
- Potassium chloride – 0.3 g;
- Magnesium chloride – 0.12 g (based on dry weight);
- Sodium hydroxide – 1.788 grams;
- Injection water – up to 1 liter.
