Lyoton gel: instructions, indications and contraindications, price, reviews

Lyoton or Heparin ointment - which is better, what is the difference

Manufacturer: NIZHFARM (Russia) Release form: ointment
Active ingredient: sodium heparin, benzocaine, benzyl nicotinate

Both drugs have equivalent indications for use, but differ in their pharmacological properties. The action of Lyoton is aimed at relieving inflammatory phenomena, normalizing the permeability of the vascular wall and preventing the formation of blood clots.

Heparin ointment has a more pronounced analgesic effect with the anticoagulant effect of heparin. Both drugs are most often used to treat thrombophlebitis of the veins of the lower extremities and thrombosis of the hemorrhoidal veins.

The use of Lyoton gel is possible only for external hemorrhoids and is contraindicated for inflammation of internal hemorrhoids. In this case, the best treatment for this disease would be Heparin ointment, which anesthetizes and relieves tension and inflammation of the venous wall.

In the treatment of thrombophlebitis of the veins of the lower extremities, Lyoton will be the best, since it contains more active substance compared to Heparin ointment, and it is available in the form of a gel.

To whom it is not assigned

The annotation for the drug contains a list containing contraindications for the use of Lyoton. The gel is not prescribed in the following cases:

When individual hypersensitivity to a medication or its components is a known fact.
If the areas of skin where the gel is supposed to be applied have ulcerative or necrotic defects.
In the presence of injuries that lead to a violation of the integrity of the skin.
Decreased hemocoagulation and thrombocytopenia.

Doctor's review

Gel "Lioton 1000" is positioned primarily as a means to relieve fatigue in the legs after work and eliminate swelling. It is also advertised as a cure for varicose veins and is prescribed by doctors for this purpose.

This positioning is not difficult to understand. There are many women with varicose veins and tired legs, but much fewer with bruises. Bruises heal quickly and go away forever, but varicose veins are a chronic disease that forces the patient to run to the pharmacy again and again to buy Lyoton 1000.

This remedy will be more effective for eliminating bruises. According to studies, it accelerates the resorption of hematomas by 2-3 times due to the high concentration of heparin, a direct anticoagulant.

However, a positive effect on the course of varicose veins is also possible. This disease cannot be cured by Lyoton. But with long-term use, a person benefits from:

reducing the inflammatory process;
reducing the risk of blood clots;
reducing the risk of thrombophlebitis;
normalization of tissue trophism by eliminating microthrombi and restoring microcirculation;
reducing the risk of the formation of trophic disorders, including ulcerative skin lesions.

For varicose veins, Lyoton 1000 should not be used as the main and only drug. It can be used as monotherapy only in the initial stages of the disease. In the future, the basis of treatment becomes oral medications, compression stockings, microsurgical procedures (sclerotherapy), and, if necessary, full-fledged surgical interventions. Lyoton 1000 cannot reverse the development of the disease. This remedy is intended for symptomatic treatment and reducing the risk of complications of varicose veins.

Compound

Heparin ointment and Lyoton ointment have differences in composition. Lyoton consists of 1000 MEg of sodium heparin. The Russian analogue contains:

Heparin sodium – 100 IU/g;
Benzocaine – 0.40 mg/g;
Benzylnicotinate – 0.8 mg/g.

Lyoton gel contains 10 times more active ingredient sodium heparin. Which is a significant difference in composition.

pharmachologic effect

There are differences between Lyoton and Heparin ointment in their pharmacological action. Therapy with Lyoton gel gives the following effect:

Anticoagulant, resulting in the formation of an obstacle to the formation of blood clots;
Anti-inflammatory;
Antiexudative, which leads to the elimination of increased permeability of vascular walls.

Heparin ointment has the following effect:

Local anesthetic, which eliminates pain in the area treated with the drug;
Anticoagulant.

When treated with Lyoton, swelling decreases, the inflammatory process is relieved, and the fluid encounters an obstacle when entering nearby tissues. The active substance remains in the blood for 24 hours after application. The highest concentration is observed after 8 hours. The gel is characterized by instant results. It perfectly relieves inflammation.

Heparin ointment is a combination product; its properties are expanded by its constituent components. This leads to improved blood microcirculation, promoting better absorption of heparin. It helps relieve pain by blocking nerve impulses.

Contraindications

Contraindications for Lyoton gels and Heparin ointment differ from each other. The first remedy must not be used when:

Individual intolerance to components;
Damaged skin;
Ulcers and necrosis of the skin;
Thrombocytopenia;
Decreased hemocoagulation;
Aneurysm of cerebral vessels;
Liver cancer;
During menstrual flow;
After childbirth, miscarriage;
After puncture;
Intracranial hemorrhage;
Stroke;
Blood clotting disorders;
After surgical interventions;
Dilatation of the esophagus;
Cirrhosis of the liver.

Heparin ointment is contraindicated in the following cases:

Injury to the skin;
Trophic ulcers;
Thrombocytopenia;
Hypocoagulation;
Individual intolerance;
Ulcerative-necrotic processes.

How to use

Lyoton gel can be taken at the initial stage of the disease, but it is also effective in more advanced processes. The gel allows you to relieve the inflammatory process, eliminate increased vascular permeability, and avoid blood clots.

In this case, it is applied to the affected area of the legs up to 3 times a day. When varicose veins begin to develop, the drug is applied to the skin with stroking movements once for 7-20 days.

In this case, swelling, heaviness in the legs, and pain in the blood vessels disappear.

Lyoton should not be used more than 3 times a day. A strip of 3-10 cm contains a single dosage of the drug.

Heparin ointment is prescribed at the initial stage of varicose veins. Thanks to its auxiliary components, it helps relieve pain in varicose veins.

Heparin ointment is applied in a thin layer and lightly rubbed in until completely absorbed 3-4 times. The course of treatment should not exceed 5 days. Usually, 3 days are enough to relieve inflammation of initial varicose veins.

If there is a need for further therapy, you should consult your doctor.

It is recommended to apply the ointment or gel only to cleansed skin.

What's better

People often wonder which is better: Heparin or Lyoton. Both drugs are used to treat varicose veins and prevent blood clots.

Lyoton contains a larger amount of the active component, the Russian drug is supplemented with components that have a strong analgesic effect. Due to this, it has a better anesthetic effect.

When comparing Heparin ointment and Lyoton, you should focus on the tolerability of the components and the doctor’s recommendation. One telling factor is the difference in cost. The price of Lyoton gel is much higher due to the large amount of active ingredient. On average in Russia it is about 250 rubles, while Heparin ointment costs about 75 rubles.

Replace with analogues

How can I replace Lyoton gel to save money? The range offered by the market is quite extensive. Some analogues are inferior in quality to the drug, but most are quite effective, but at the same time they are cheaper.

To determine analogues, it is necessary to focus on the composition of the Lyoton 1000 gel, the main active component of which is heparin.

A similar effect occurs:

hepatrombin;
lavenum;
viathromb;
Venabos gel;
troxevasin;
dolobene;
contractubex;
heparin ointment.

A drug such as contractubex contains a lower concentration of the active substance, but includes Serae extract, which has anti-inflammatory and bactericidal properties. The product heals wounds and scars well, but works less well for varicose veins.

Hepatrombin also contains a lower concentration of heparin than is included in the drug Lyoton, and the medicine includes:

allantoin;
lemon oil;
pine needle oil;
Dexapanthenol.

As a result, its anticoagulant effect is lower and the rest slightly better.

Dolobene gel exhibits an antithrombotic effect due to the content of additional substances such as dimethyl sulfoxide and dexapanthenol. The product effectively anesthetizes the skin area, relieves inflammation and pain, activates metabolic processes under the skin, accelerating the restoration of the skin.

Troxevasin is prescribed to strengthen the walls of capillaries and reduce their permeability. The product allows you to eliminate trophic disorders in varicose veins and block inflammation of the perivenous tissue.

Venitan forte contains a venotonic agent and a direct anticoagulant. The second is heparin, and the tonic is escin, extracted from horse chestnut seeds. Escin has a positive effect on the condition of blood vessels, strengthening their walls and increasing tone, which helps reduce congestion in the veins and get rid of swelling.

Russian analogues

Among the drugs developed by domestic pharmacologists, the following have a similar effect:

trombless gel;
heparin;
hepasolone;
lavenum;
heparin ointment;
Venolife;
heparin-acrigel 1000.

Let's look at them in more detail below.

Trombless

An analogue of Lyoton gel, produced in Russia, contains the same concentration of active ingredients and is very similar in application to Lyoton gel. Many patients, having started using this drug, did not notice any difference, but the difference in price is about 150-200 rubles.

Venolife

The product contains vitamins P and group B, has an effect on tissue regeneration and normalization of blood microcirculation. Can be used even during pregnancy and breastfeeding. However, due to the low content of heparin, it is not effective in severe cases of the disease.

Lavenum

Another domestic drug that exhibits antimicrobial, anti-inflammatory and decongestant effects. Recommended for use for thrombophlebitis, tendon and joint injuries, hematomas, and swelling of the legs.

Hepazolon

In addition to heparin, it contains prednisolone, which reduces the formation and efficiency of inflammatory mediators, reduces vascular permeability and reduces the body's allergic reaction.

The lidocaine included in the drug anesthetizes the affected area by blocking the transmission of nerve impulses. When used together, they significantly enhance each other’s effect, allowing you to achieve quick results.

Heparin ointment

One of the cheapest drugs, which includes, in addition to heparin, other active ingredients: a vasodilator - benzyl nicotinate and an anesthetic - benzocaine. Shows a noticeable effect in the treatment of thrombophlebitis and deep vein thrombosis. The cost of the drug usually fluctuates around 70-100 rubles.

Heparin is a cheap analogue of Lyoton 1000 gel, having a similar composition and concentration of the active ingredient. Additional elements of the product are essential oils of neroli and lavender. They have an antiseptic and antimicrobial effect, and also tighten and rejuvenate the skin.

Heparin, created a little later than heparin ointment, is more effective.

In pharmacies it can be found under the name “Heparin-Acri gel 1000”.

Lyoton gel: analogues

Currently, two types of Lyoton 1000 gel analogues are offered.

The first group of drugs is based on the use of sodium heparin as an active component. These are Heparin-Acrigel 1000, Trombless, Heparin, Laventum.

The second group of analogs has a similar therapeutic effect. These include Heparin ointment, Venolife, Gepatrombin, Troxevasin, Dolobene.

Mode of application

The product is produced in the form of a gel, so it is convenient to apply it externally by squeezing a little of the product out of the tube; for one time you can squeeze out 3 to 10 cm of the product so that it can be rubbed well into the skin.

At the same time, you need to expect that you need to use Lyoton from 1 to 3 times a day, so you should immediately buy at least two tubes, this supply of medicine will allow you to complete a full course of therapy. You can independently determine the supply of the medicine, taking into account that about 1 gram of the product is needed for an area with a diameter of 5 cm (approximately 10 cm in squeezed form).

On average, the course of using the gel is three weeks, but for each specific disease, its own timing:

In case of inflammatory processes, it is advisable to use it for 1 week, and most often the period of use can be limited to 3 days;
For edema, swelling, bruises and injuries, treatment with gel is carried out until they are completely eliminated;
For skin ulcers, gel is applied to the skin around them until they go away;
At the beginning of varicose veins, when the spider veins only appear, it will be enough to use the product for a month;
In chronic cases of varicose veins, treatment lasts from 1 to 6 months.

To do this, the drug is applied to a calico pad, which will need to be fixed with a bandage on the pinched nodes, or a special rectal tampon is used, inserted into the anus. This treatment is carried out for 3 days.

Terms of use

If the patient has external hemorrhoids, it will be convenient for him to make a compress. You need to apply the gel to the gauze and then apply it to the sore spot. If there are hemorrhoids from the inside, prepare a gauze tampon, apply Lyoton to it and insert it through the sphincter. Using gel in a tampon prevents swelling and blood clots from forming there. The nozzle on the packaging of the medicine can also help in eliminating the manifestations of internal hemorrhoids. It is inserted into the anus and the required amount of substance is squeezed out through it. It is not recommended to use it in the presence of bleeding and distribute it over damaged tissues. The course of treatment is up to 1 week. During this period, the patient stops feeling discomfort, burning or itching in the rectal area, and gets rid of inflammation and swelling of hemorrhoidal cones. The use of the gel prevents the development of infection that can enter the body through anal fissures, and also helps relieve pain.

Lyoton gel for the treatment of hemorrhoids

A separate question: is it possible to use the drug during pregnancy? Clinical studies have proven that the use of this drug has no effect on the fetus and does not increase its risk of pathologies. Therefore, it is appropriate to use the medication during pregnancy and after childbirth. It will help relieve swelling and eliminate discomfort in the rectal area. One contraindication for the drug for hemorrhoids during pregnancy, as well as for other patients, still exists - an allergic reaction to any components, in particular to heparin.

Analogues of Lyoton 1000

Russian analogues

Trombless

The composition includes: sodium heparin, troxerutin, dexpanthenol, benzocaine and excipients: ethanol, methyl parahydroxybenzoate, trolamine, carbomer, glycerol.

The gel has the following actions:

anti-inflammatory;
antiproliferative;
decongestants;
painkillers;
promotes rapid resorption of blood clots and hematomas;
helps restore vein patency;
restores cellular metabolism;
stimulates tissue regeneration;
venotonic;
relieves the inflammatory process of vascular walls.

A side effect can be expressed in the manifestation of local reactions, namely: skin itching, rashes, hyperemia.

Indications: injuries, bruises, varicose veins of the lower extremities, subcutaneous hematomas, swelling, consequences after surgery on the veins of the legs.

Contraindications: allergies to components, pregnancy, breastfeeding, age under 18 years, existing open wounds on the skin, tendency to bleed.

Application: spruce is applied in a thin layer to the affected area and a little near it. Lightly rubbing the gel in a circle. Application is allowed 1-2 times a day. The course of treatment can last on average up to 3 weeks.

Average cost of the drug: 260 rubles.

Trombless

Venolife

The composition includes: troxerutin 20 mg, sodium heparin 2.5 mg, dexpanthenol 50 mg and excipients such as purified water, trometamol, phenylethyl alcohol, propylene glycol.

The drug has:

pro-inflammatory effect;
helps regenerate connective tissue;
prevents thrombosis;
improves blood flow;
reduces vascular permeability;
reduces stagnation;
bactericidal effect.

There are adverse reactions: slight itching, skin rash.

Indications: swelling, venous insufficiency of the lower extremities, hematomas, dislocations, sprains.

Contraindications: open wounds, individual intolerance.

Application: apply the gel in a thin layer, then rub in slowly. The course of treatment lasts on average up to 3 weeks. Can be used up to 3 times a year.

The average cost of goods is: 750 rubles.

Venolife

Lavenum

The composition includes sodium heparin and auxiliary components: methyl parahydroxybenzoate (nipagin or methylparaben), ethanol (rectified ethyl alcohol), carbomer (carbopol), trolamine (triethanolamine), lavender essential oil, purified water.

The ointment inhibits blood clotting and also has anti-inflammatory, anti-edematous and antithrombotic effects to a lesser extent.

Complications after using the drug are possible in the form of skin hyperemia and allergic reactions.

Indications: tendon injuries, joint bruises, swelling, infiltrates, thrombophlebitis of superficial veins.

Contraindications: thrombocytopenia, skin ulcers, high blood clotting, deep venous thrombosis, bleeding, purulent processes on the skin, open wounds.

Application: apply the drug in a thin layer, slowly rubbing into the skin. Apply up to 3 times a day. The course of treatment lasts up to 7 days on average.

The average cost of goods is: 220 rubles.

Lavenum

Heparin ointment

The ingredients include: sodium heparin, benzocaine, benzyl nicotinate. It is considered a combination drug for external use.

Indications:

relieves the inflammatory process;
gives an antithrombotic effect;
improves blood clot resorption;
capable of blocking thrombus synthesis;
significantly reduces hyaluronidase activity;
reduces pain (has a local analgesic effect).

Indications:

hemorrhoids (external);
post-injection phlebitis;
post-infusion phlebitis;
thrombophlebitis of veins;
trophic ulcers;
elephantiasis;
lymphangitis;
superficial mastitis;
swelling;
injuries;
bruises;
hematomas.

Contraindications: individual intolerance; skin disorder; bleeding; thrombocytopenia.

Application: the drug must be applied in a thin layer to the affected area and rubbed in slowly. Apply up to 3 times a day. The course of treatment lasts on average up to 7 days.

You can read more about effectiveness in the article “Ointments and gels for varicose veins, the difference between them, a description of the most effective ones.”

The average cost of the drug is 50 rubles.

Heparin ointment

Imported substitutes

Ukraine:

heparin gel;
Heparil 1000 gel;
Heparin - Darnitsa;
Dioflan gel;
Liothromb.

Belarus:

Heparin gel;
Heparin;
Heparin Active.

Analogues of gel Lyoton 1000

What is the difference between heparin ointment and gel?

Heparin ointment and gel differ in dosage, composition, auxiliary components and manufacturers.

Ointments contain three main components:

heparin is a direct anticoagulant;
benzocaine is an anesthetic component necessary to block nerve impulses;
benzyl nicotinate is a vasodilator necessary to improve blood flow and also enhance the absorption of heparin.

Produced by many pharmaceutical companies and called “Heparin ointment”, the dosage of the active component is 100 IU (international units). It differs from the gel in a fattier, thicker consistency.

Depending on the manufacturer, the gel may contain 1000 or more units of active substance. There are no additional active ingredients. For example, a gel with the trade name Lyoton includes only heparin with a dosage of 1000 IU. Form-forming components provide light texture and rapid penetration into the skin, unlike ointment.

A number of gels are produced that, in addition to the active component, also contain additional ones. Thus, Troxevasin Neo contains dexpanthenol.

and
troxerutin
. Panthenol is necessary for healing skin defects, enhancing the absorption of the anticoagulant, accelerating metabolic processes in affected tissues. Troxerutin strengthens the venous wall, preventing the diffusion of the liquid part of the blood. Therefore, the heparin gel Troxevasin Neo for edema is used for varicose veins of the lower extremities.

Venitan Forte, in addition to the described anticoagulant in a dosage of 100 IU, contains panthenol, escin and allantoin. Escin is obtained from horse chestnut; this component reduces inflammation, swelling, and increases the tone of the venous wall. Allantoin is necessary to enhance the effect of heparin.

The Gepatrombin line of gels and ointments includes various components. The classic drug contains 300-500 IU of heparin in 1 gram. Gepatrombin G ointment with 65 IU of anticoagulant is additionally supplied with the hormonal anti-inflammatory component prednisolone. Gel “C” (500 IU of heparin), consisting of panthenol and dimethyl sulfoxide - an antimicrobial, anti-inflammatory, analgesic substance.

What to choose?

So, the ointment differs from the gel in a significantly lower amount of heparin per gram, the presence of additional components and a greasy texture. The choice in favor of a single-component remedy or a combined one depends on the type of disease, and the dosage depends on the severity.

If there are mild local circulatory disorders (slow healing or resorption) without pain, then a small amount of heparin in gel form (regular Hepatrombin, a small amount of Lyoton) is sufficient.

Mainly, heparin-containing gels at a dose of 1000 units/g (Lioton, Trombless) are used for varicose veins and the symptoms that accompany them. These include swelling of the legs, fatigue, pain, expansion of the saphenous veins, and telangiectasias. Heparin gel in cosmetology successfully copes with spider veins and helps with cellulite. It is used as part of combination treatment, in particular, after sclerosis of dilated capillaries.

Varicose veins of the rectum and anus (internal and external hemorrhoids) are also treated with an anticoagulant gel (Hepatrombin G) or ointment (Proctosedyl).

When choosing an ointment or gel that is better for the treatment of trophic ulcers, you should pay attention to conventional ointments or combined gel products: Troxevasin Neo, Dolobene. These drugs have a healing, anti-inflammatory and antioxidant effect.

Pharmacological possibilities

The basic active ingredient of Lyoton is heparin. The product is obtained from the internal organs of cows and pigs. Thanks to its impact:

Blood density decreases;
The permeability of the vascular system, provoked by biogenic amines or other reasons, is reduced;
Congestion in the veins is prevented;
The negative potential of blood cell membranes increases, this helps reduce the adhesive and aggregative effects of platelets and other components;
Excessive growth of smooth muscles is blocked;
The risk of atherosclerotic changes is reduced;
The aggression of the complement system is reduced, this is reflected in the inhibition of the process of cooperation of lymphocytes and the synthesis of antibodies; the antiallergic effect is manifested in the binding of serotonin and histamine;
In the lungs, the active effect of surfactant is inhibited;
The work of the endocrine system is stimulated by binding adrenaline, inhibiting excess production of aldosterone, controlling the ovarian response to hormonal activity, increasing the activity of parathyroid hormone.

According to the pharmacological classification, heparin belongs to the class of anticoagulants, which, in turn, is divided into 2 groups:

Direct anticoagulants - such as heparin, bemiparin, apixaban, etc.;
Indirect anticoagulants - such as warfarin, phenindione, etc.

Features of the mechanism of action of heparin as a direct acticoagulant are manifested in a direct effect on coagulation and inhibition of each phase in the process of blood clotting.

The gel treats inflammation and swelling, eliminates excessive permeability of veins, which provokes the release of valuable biological fluids into the tissue. The medication prevents the formation of clots, normalizes blood clotting, and prevents platelets from sticking together. The maximum effect after applying the gel can be expected after 8 hours, while heparin works in the blood throughout the day. The compound is eliminated in urine.

Features of application

Lyoton 1000 belongs to the group of medium molecular weight heparins; it is a direct anticoagulant. Its components give the medicine anti-inflammatory, anti-exudative and antithrombotic effects.

After therapy they observe:

Improving the condition of blood vessels and increasing their tone;
Normalization of hemorheological failures;
Prevention and elimination of inflammatory processes on the walls of veins with or without blockage;
Improved blood clotting;
Increased lymphatic drainage;
Restoration of changes in the veins by eliminating their strong lumen;
Elimination of varicose ulcers, which are often present on the lower extremities;
Reducing swelling of the legs;
Elimination of bruises not only of muscle tissue, but of joints and tendons;
Relief after operations performed on veins;
Elimination of subcutaneous hematomas that occur due to the accumulation of blood in the tissues.

Lyoton is primarily used to block thrombin; it activates fibrinolytic factors and inhibits the activity of hyaluronidase, while improving metabolic processes in tissues.

Composition, dosage form

The gel is sold in metal tubes with dosages of 30 g, 50 g, 100 g. The tubes are packaged in cardboard boxes.

The gel is a translucent colorless mass, sometimes with a yellowish tint. The medicine has a pleasant smell due to the content of essential oils.

The main component of the composition is sodium heparin (1000 IU), and it also contains auxiliary components:

ethanol;
water;
propyl parahydroxybenzoate;
essential oils of neroli and lavender;
trolamine;
methyl parahydroxybenzoate;
carbomer 940.

It is sold in pharmacies without a prescription, but before use it is recommended to obtain the approval of a specialist (phlebologist, therapist, traumatologist, etc.).

Indications and contraindications for treatment with Lyoton

The scope of therapeutic action of the drug is quite extensive. It is intended not only for the treatment of proctological pathologies, but also many other diseases . Direct indications for prescribing Lyoton 1000 ointment are:

external and internal hemorrhoids with the formation of thrombosed nodes;
inflammation of hemorrhoidal cones without bleeding;
anal ulcerations, fissures;
thrombophlebitis (inflammation and blockage) of superficial veins;
phlebitis of the venous walls;
chronic varicose veins of the extremities;
varicose ulcers of the lower extremities;
non-infectious swelling and compaction;
Terms of use. "Lioton" for hemorrhoids
subcutaneous hematomas;
injuries to muscle tissue, joints, tendons;
postoperative complications on the veins, including hemorrhoids.

"Lioton" in the treatment of hemorrhoids is used mainly as part of complex or preventive therapy. As an independent remedy, it helps relieve uncomfortable symptoms, but is unable to eliminate the cause of the disease. The gel can be used as first aid in case of sudden exacerbation of pathologies of the rectum and perianal area. In each individual case, the need to prescribe this drug is determined by the diagnosis and well-being of the patient.

Before starting treatment, you must familiarize yourself with all possible contraindications. Among the strict prohibitions in the instructions are:

hypersensitivity to heparin or additional components;
open and bleeding wounds;
bleeding disorders (thrombocytopenia, hemophilia);
tendency to bleed;
trophic ulcers of the lower extremities;
hemorrhagic diathesis.

If the mentioned conditions are not detected, antihemorrhoidal therapy with Lyoton 1000 can be carried out on the recommendation of a doctor.

Lyoton 1000 gel 1000 units/g, 100 g

Instructions for use of Lyoton 1000 gel, doses and rules

The gel is used externally only; after application to the skin, rub in gently with light movements. Standard dosage recommended by the instructions for use of Lyoton gel - a strip 3 to 10 cm long

Frequency of application – up to 3 times a day

The standard dosage recommended by the instructions for use of the Lyoton gel is a strip 3 to 10 cm long. The frequency of application is up to 3 times a day.

In the case of a leg ulcer, gently lubricate the inflamed skin around the ulcer. The gel is used daily until the inflammation disappears (on average from 3 to 7 days, the possibility of a longer course of treatment is determined by the doctor)

The gel is used daily until the inflammation disappears (on average from 3 to 7 days, the possibility of a longer course of treatment is determined by the doctor).

Important information

Lyoton 1000 gel should not be applied to open wounds, mucous membranes, or in the presence of purulent processes.

Use is not recommended for deep venous thrombosis.

Use during pregnancy and lactation

Lyoton gel can be prescribed during pregnancy and breastfeeding.

Heparin does not cross the placental barrier and is not detected in breast milk. Since it is only slightly absorbed when used externally, the drug does not have a systemic effect on the body.

Pregnant and breastfeeding women should consult a doctor before starting treatment.

Lyoton: composition and release form

The drug is made using the active component sodium heparin, which helps thin the blood in the vessels and activates the internal blood flow.

The action of the active substance is due to its interaction with blood proteins, which reduces blood clotting. Penetrating into the blood vessels, heparin gradually dissolves the formed blood clots, activates the activity of the excretory system, and reduces the risk of thrombophlebitis and a number of heart diseases.

Lyoton gel also contains additional components: carbomer, triethanolamine, methyl parahydroxybenzoate, propyl parahydroxybenzoate, lavender and neroli oil, purified water.

The drug is produced in the form of a colorless homogeneous gel.

Indications for use

The use of Lyoton gel is indicated for the following diseases and pathological conditions:

phlebeurysm;
thrombophlebitis, phlebothrombosis, periphlebitis;
swelling of the lower extremities;
consequences of injuries: bruises, sprains, dislocations;
bruises and hematomas, subcutaneous hematomas;
angina pectoris;
myocardial infarction;
mitral heart disease;
superficial mastitis;
haemorrhoids;
spider veins on the face.

To relieve swelling, women often apply gel to their face. This should be done with great caution due to possible allergic reactions and the likelihood of the drug getting on the mucous membranes of the eyes.

How does Lyoton 1000 work?

The gel is intended for external use. It is a viscous, transparent mass. Available in a special tube. The volume can be 30, 50, 100 g.

The gel has an antithrombotic, antiexudative effect, and also has a moderate anti-inflammatory effect.

Gel Lyoton 1000

When Lyoton is applied to problem areas of the skin, the gel begins to act. Actions:

able to relieve swelling;
prevents fluid from escaping into adjacent tissues;
helps blood vessels eliminate high permeability of the walls;
helps get rid of high blood clotting;
eliminates the inflammatory process.

The gel penetrates into the blood partially through the systemic circulation. However, this does not cause any pathological processes in the blood clotting system. After a course of using the drug, heparin is present in the patient’s blood. Disappears within 24 hours after application. But do not forget that the gel is able to penetrate the placental barrier. The gel is indicated for various diseases, namely:

superficial wound disease;
complication of phlebothrombosis;
thrombophlebitis;
superficial periphlebitis;
complication after vein surgery;
after injuries;
with sprains;
in case of injury (damage) to soft tissues;
with swelling;
for resorption of subcutaneous hematomas;
joint bruises.

The gel, like all medications, has its contraindications, these include:

traumatic damage to the skin;
individual intolerance to the composition of the gel;
ulcers on the skin, any necrotic changes;
reduced hemocoagulation;
thrombocytopenia;
existing bleeding;
purulent processes present on the skin.

As practice shows, this remedy has proven itself well, and at the same time, apart from an allergic reaction, it does not cause any complications.

How to apply the gel correctly

You should first consult a doctor. Since the duration of treatment and dose directly depend on the severity of the disease.

The amount of the drug must be applied depending on the volume of tissue damage. For this there is a special strip up to 10 cm long.
The gel is applied in a thin layer and gradually rubbed in gently.
In the presence of hematomas, swelling and injuries, the drug is used until the symptoms disappear.
For initial degrees of varicose veins of the lower extremities, the gel is used for a course of up to 3 weeks.
For chronic venous insufficiency, the gel can be used for up to 6 weeks.

Overdose of this drug is practically never observed in practice. The reason is that the systemic absorption of sodium heparin is very low.

If a child accidentally swallows the gel, nausea and vomiting may occur. In this case, it is necessary to urgently rinse the child’s stomach and consult a doctor.

Lyoton 1000 can be stored in a room where the air temperature does not exceed +25 degrees. This storage location must be inaccessible to children.

Drug interactions

It is not recommended to use simultaneously with other products for external use. Also, do not use simultaneously with non-steroidal anti-inflammatory drugs, antihistamines, tetracyclines.

Available in pharmacies without a prescription.

The main action of Lyoton gel

Dilated veins with varicose veins are associated with insufficient functioning of the valves. Due to their weakness, a large volume of blood accumulates in the vessels, which makes it even more difficult for it to move from the lower extremities towards the heart. Since the valves cannot completely prevent the reverse flow of blood, swelling of the tissues occurs, heaviness in the legs, and blood clots begin to form against the background of lymphatic and venous stagnation.

Properties of Lyoton gel

Manifestations of venous insufficiency increase with increased blood coagulation activity. The main effect of heparin, which is part of Lyoton gel, is aimed at eliminating this factor. Unlike external agents based on bioflavonoids (Troxevasin, Venoruton, Phleboton), the drug not only improves venous outflow and lymph drainage, but also directly affects blood fluidity:

reduces viscosity;
resolves blood clots;
inhibits platelet aggregation (sticking together);
binds and neutralizes compounds that damage the inner lining of veins;
reduces the possibility of blood clots attaching to the vascular wall.

At the tissue level, heparin has the ability to restore the passage of ions through cell membranes, blocks enzymes involved in the inflammatory process, reduces the activity of platelet factors, and also stimulates cellular immunity. Thanks to these biological effects, anti-edematous, analgesic and regenerating effects are manifested.

One of the important features is Lyoton’s ability to prevent a serious complication of varicose veins - acute thrombophlebitis.

Recommendations for use

Phlebologists emphasize that the best effect when using Lyoton gel is achieved:

When wearing special compression garments or knitted bandages, comfortable shoes with low heels or wedges.
Maintaining a daily routine: alternating rest with walks. During rest, your legs should be in an elevated position.
Taking a contrast shower for your feet. Jets of cool (+20 degrees) and warm water (+45 degrees) alternate every 15 seconds. Start the procedure with one minute and gradually increase to 10 minutes.
Swimming lessons, which should be individually selected by a doctor and trainer.

If the recommendations are not followed, vein diseases continue to progress and their development cannot be stopped using Lyoton gel.

Possible side effects and overdose of Lyoton gel

When using the drug Lyoton gel, possible side effects should be taken into account. The results of clinical observations allow us to conclude that side effects when using this drug are unlikely, but we cannot exclude the possibility of an individual negative reaction of the body to heparin (individual intolerance to heparin)

In such cases, dermatological reactions are possible at the sites where the drug is applied, which resemble allergic ones:

The results of clinical observations allow us to conclude that side effects when using this drug are unlikely, but we cannot exclude the possibility of an individual negative reaction of the body to heparin (individual intolerance to heparin). In such cases, dermatological reactions are possible at the sites where the drug is applied, which resemble allergic ones:

Possible itching of the skin;
Redness of the skin may be observed;
Skin rashes may occur;
Peeling of the skin is possible.

If a dermatological reaction occurs in response to the use of Lyoton gel, you must stop using it - the symptoms of the allergic reaction will quickly disappear without the use of any additional therapeutic measures.

As for the possibility of overdose when using Lyoton gel, such cases are unknown. However, during studies of the drug, it was revealed that the antidote that neutralizes the effect of heparin is protamine sulfate.

special instructions

Additional substances of the drug are methyl and propyl p-hydroxybenzoate. Therefore, Lyoton is not recommended for use by people who have established allergic reactions to parabens.

In people who have hemorrhagic symptoms, it is very important to carefully evaluate the appropriateness of using this substance. Lyoton should not be used for bleeding

Also contraindications include purulent lesions of the epithelium.

Do not apply the composition to infected areas of the dermis, open wounds, or mucous membranes. The same applies to the skin around the eyes. In addition, contact of the substance with the eyes should be avoided.

When treating phlebitis, it is forbidden to rub the composition into the skin.

There is no sufficient experience with the use of the substance in children. Therefore, the drug is not recommended for this category of patients.

What therapeutic effect does Lyoton-gel have on hemorrhoids?

"Lioton 1000" belongs to the drugs used for varicose veins. The main manifestation of hemorrhoids are nodular formations on the walls of the rectum, which periodically become inflamed and thrombosed. The drug prevents this pathological process, improving blood microcirculation and metabolic processes .

How to replace the gel

Heparin, a product with the active ingredient of the same name, is produced by domestic pharmaceutical enterprises: Tatkhimfarmpreparaty and the Murom Instrument-Making Plant. Dosage – from 15 to 100 g.
Viatromb is sold in the pharmacy chain in the form of a gel spray with a capacity of 25 ml. The main active substance is also heparin. An important feature of the analogue is safety: it is prescribed both in childhood and during pregnancy. The medicine is produced in Europe, in the German company Fabril Pharma GmbH.
Heparin-Acrigel complements the list of this category of drugs. The manufacturer of the medicine is domestic Akrikhin.
Lavenum is packaged in 30, 50 and 100 g. An analogue is produced at the Russian JSC Sintez.
Trombless can also be found in a combined version with the addition of dexpanthenol, troxerutin and benzocaine under the trade name. Troxerutin is a flavonoid with venotonic and angioprotective capabilities that treats chronic venous insufficiency, edema, and inflammation. Benzocaine is a local anesthetic component. Dexpanthenol restores and moisturizes the skin. Gels are produced at the domestic NIZHFARM.
Thrombogel is identical in its characteristics to Lyoton. Sold in tubes of 15 and 30 g, produced at the Belarusian enterprise Belmedpreparaty.

Among the combined similar medications, where heparin is combined with other angioprotectors:

Venitan Forte, developed in Slovenia at the Lek company based on heparin and escin. The latter contains horse chestnut saponins, which have anti-inflammatory, anti-edema, and venoprotective capabilities.
Venolife is close in structural composition to Trombless Plus, since in addition to heparin it also contains dexpanthenol and benzocaine. The Russian Akrikhin produces a gel packaged in 30-100 g.
Hepatrombin is presented by the Serbian pharmaceutical company Hemofarm in the form of ointment and gel. The basic components heparin and dexpanthenol are supplemented with allantoin. The medicine has restorative and astringent properties.

In terms of safety, Troxevasin also loses: in addition to the allergic consequences that Lyoton also has, headaches and abdominal discomfort are possible. The analogue is not prescribed to nursing mothers. Patients, judging by the reviews, also prefer Lyoton: it does not have a strong odor or sticky application.

Doctors consider Troxevasin to be just an anti-inflammatory drug that is not able to influence the severe symptoms of varicose veins.

What is the difference between heparin ointment and gel?

Heparin ointment and gel differ in dosage, composition, auxiliary components and manufacturers.

Ointments contain three main components:

heparin is a direct anticoagulant;
benzocaine is an anesthetic component necessary to block nerve impulses;
benzyl nicotinate is a vasodilator necessary to improve blood flow and also enhance the absorption of heparin.

25 g

A number of gels are produced that, in addition to the active component, also contain additional ones. Thus, Troxevasin Neo contains dexpanthenol.

What to choose?

If there are mild local circulatory disorders (slow healing or resorption) without pain, then a small amount of heparin in gel form (regular Hepatrombin, a small amount of Lyoton) is sufficient.

Varicose veins of the rectum and anus (internal and external hemorrhoids) are also treated with an anticoagulant gel (Hepatrombin G) or ointment (Proctosedyl).

Other uses of the drug

Some people use Lyoton-gel for the face. The reviews here are very positive: swelling is relieved, wreaths disappear. As a rule, the remedy in question is used after a sleepless night to remove bags under the eyes or to cure bruises. However, you should not overuse the gel; after all, the main indications for its use are completely different. You should not use it for acne on the skin, and in other cases, when applying, make sure that the gel does not get into your eyes.

Description and characteristics of the drug Lyoton

Lyoton gel is a medicinal product intended for external use. The basis of the drug is the active component - sodium heparin 100 g. It is a direct anticoagulant and prevents blood clotting. The active substance is absorbed into the blood slightly and this is achieved only after application to the affected area after 8 hours.

The substance is excreted by the kidneys, which is very important during pregnancy and lactation.

Additional substances included in the drug: ethanol, methyl parahydroxybenzoate, carbomer, lavender and neroli oils, trolamine.

Essential oils have a relaxing effect and also reduce discomfort and pain.

The drug Lyoton gel has the following pharmacological actions:

Anti-inflammatory
Antiexudative
Decongestant
Anticoagulant

The remedy is available in the form of a gel. The consistency is viscous, colorless or yellowish. Lyoton gel improves tissue metabolism. As a result, hematomas, bruises and blood clots resolve, swelling decreases.

"Lioton" in the treatment of hemorrhoids: adverse reactions and precautions

Treatment with Lyoton 1000, provided that medical recommendations and instructions are followed, is successful in most cases. Patients tolerate the drug well and note a significant improvement in well-being after a week's course . In exceptional situations, undesirable reactions may occur, which you should pay attention to:

redness, burning, itching of the skin;
rashes like urticaria;
angioedema as a severe allergy to the components;
hemorrhages (hemorrhages) in the anorectal area.

No cases of overdose were identified. If the gel is used uncontrolledly or used for other purposes (accidental ingestion), symptoms of intoxication or systemic reactions of the body may appear. It is necessary to seek medical help and carry out symptomatic therapy .

"Lioton 1000" is a safe product, but some precautions must be observed:

topical heparin should not be used simultaneously with anticoagulant drugs; the prothrombin time may increase;
tetracycline, salicylic acid, hydrocortisone are incompatible with Lyoton;
The gel should not be used by people allergic to parabens contained in the drug;
Gel Lyoton 1000 for the treatment of hemorrhoids
For bleeding and blood clotting disorders, treatment is carried out very carefully, with a small amount of gel.

The drug does not affect psychomotor reactions, so there are no restrictions on the control of transport and complex mechanisms.

Side effects Lyoton

Dizziness, headaches, nausea, anorexia, vomiting, diarrhea, alopecia; early (2-4 days of treatment) and late (autoimmune) thrombocytopenia; hemorrhagic complications - bleeding in the gastrointestinal tract or urinary tract, retroperitoneal hemorrhages in the ovaries, adrenal glands (with the development of acute adrenal insufficiency), osteoporosis, soft tissue calcification, inhibition of aldosterone synthesis, increased levels of transaminases in the blood, allergic reactions (fever, rashes, bronchial asthma, anaphylactoid reaction), local irritation, hematoma, pain upon injection.

Varicose veins during pregnancy

Varicose veins are the most common disease of the vascular system. Pregnancy often provokes its appearance.

This disease develops as follows: blood is sent through the artery to the lower extremities, and then, as a result of compression of the vessels, it does not immediately return to the heart. As a result, the venous outflow of blood is disrupted. In the blood vessels of the lower extremities, blood stagnates, the pressure in the walls increases and gradually leads to deformation.

Veins may dilate due to an increase in the volume of circulating blood in a pregnant woman. This is due to the fact that not only the pregnant woman, but also the fetus is provided with blood. Also during pregnancy, blood can change its rheological properties. As a result, blood viscosity increases, but the speed of blood flow in the vessels decreases.

The following symptoms are characteristic of varicose veins:

Heaviness and fatigue in the legs
The appearance of spider veins
Edema of the extremities
Cramps in the calf muscles
Painful sensations
Itching
Pigment spots on affected areas

Many women during pregnancy experience discomfort and heaviness in their legs. All this is due to venous insufficiency. It arises from

Before using the drug, you should read the instructions

Due to weight gain, this increases the load on the veins.

This unpleasant phenomenon can only be treated with special ointments or gels. One such medicine is Lyoton gel.

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Analogues of Lyoton ointment for hemorrhoids

Analogues of Lyoton 1000 gel
If there is a clinical need to replace the drug or individual hypersensitivity to prednisolone, you can choose an analogue. There are drugs that contain one of the components of Lyoton, as well as drugs with similar pharmacological effects.

Heparin contains:

Heparin ointment;
"Hepatrombin";
"Heparin";
"Trombless";
"Heparoid";
"Heparil";
"Liothromb";
"Liogel";
"Aescin";
"Venitan Forte";
"Venosan";
"Dermaton";
"Esphatil."

You can also use antihemorrhoidal gels - “Thrombocid”, “Heparoid Zentiva”, “Venolife”.

What is the effect of heparin based on?

Heparin is an organic substance of animal origin, an anticoagulant, and belongs to the water-soluble glycosaminoglycans. This compound is found in the so-called mast cells of animal organisms, which secrete a variety of physiologically active substances (including heparin) to combat inflammation and allergens. Heparin got its name due to its high content in the liver. It prevents the formation of blood clots due to interaction with blood antithrombin. The latter, in combination with heparin, greatly enhances its inhibitory effect on blood clot-forming proteins (compounds that promote the formation of blood clots). Therefore, heparin is the main component of many antithrombotic drugs.

Indications for use

Unstable angina, acute myocardial infarction; thromboembolic complications during myocardial infarction, operations on the heart and blood vessels, thromboembolism of pulmonary and cerebral vessels, thrombophlebitis; DIC syndrome, prevention of microthrombosis and microcirculation disorders; renal vein thrombosis; hemolytic-uremic syndrome; atrial fibrillation, mitral heart defects; bacterial endocarditis; glomerulonephritis; lupus nephritis; rheumatism; bronchial asthma; carrying out extracorporeal methods (extracorporeal circulation during cardiac surgery, hemosorption, hemodialysis, peritoneal dialysis, cytapheresis), forced diuresis; flushing venous catheters.

How to use the drug

When treating bruises and other various injuries, the product is applied in a thin layer to the skin and rubbed into the affected area. This procedure should be performed at least 3 times a day. The course of treatment lasts until the hematomas, bruises, and swelling completely disappear.

Treatment of varicose veins in the legs at the initial stage, which is characterized by heaviness in the legs, burning, and the appearance of small capillaries, can last for 1-3 weeks.

For varicose veins and chronic thrombophlebitis, treatment can last up to six months.

In many cases, a heparin-based drug is used on the face. It is recommended to apply the gel carefully so that the composition does not get into the eyes or lips. You should be careful when applying the drug near the eyes. It is better to avoid this area, as it can cause irritation in this thin area of skin.

When treating thrombosis of hemorrhoidal veins, the drug is administered rectally. This method allows the active substance to be quickly absorbed and absorbed into the blood vessels.

The drug is not able to change the blood formula and acts locally, so negative consequences for the pregnant woman and the fetus are not detected. To get rid of swelling and dilated veins, the gel can only be used under the supervision of an obstetrician-gynecologist.

Taking into account individual characteristics and the degree of damage, the doctor selects an individual course of treatment. Do not rub or rub the gel too much. If the process has gone very far and led to the appearance of blood clots, one of them may break off and lead to blockage of the lumen of the vessel.

Do not use the gel for pustular diseases, open wounds or ulcerative lesions. The gel should not be applied to mucous membranes or wet wounds.