How to use vitaprost in the treatment of prostatitis

Inflammation of the prostate gland is diagnosed on average in 55% of men over the age of 50, less often in young people over 20 years of age.

In the initial stages of the disease, not everyone experiences unwanted symptoms, and some patients try to solve the problem on their own.

That is why in some cases visits to the doctor are recorded already in advanced stages of prostatitis.

If a man has painful and complicated urination, pain in the lower abdomen, or deterioration of erectile function, he should immediately consult a specialist.

Severe forms of the disease, as well as complications caused by the disease, can lead to irreversible disorders of the reproductive function and genitourinary system in men, including infertility, impotence, prostate abscess and other pathological conditions.

For quick and effective treatment of prostatitis, modern drugs are used, including the drug Vitaprost Plus, based on natural ingredients with a pronounced anti-aggregation and anti-inflammatory effect.

One of the components of the medication is lomefloxatine, an antibacterial agent for the treatment of inflammatory and infectious processes in the genitourinary system.

The mechanism of action of the drug Vitaprost Plus is to reduce tissue swelling, restore secretion production, stimulate the smooth muscle layer in the bladder and improve the characteristics of seminal fluid.

Vitaprost Plus also activates a man’s erectile function and increases the level of activity and viability of sperm.

Active substance: history of creation and properties

"Vitaprost" is a generic . The original drug is called “Prostatilen” (the effectiveness of “Prostatilen” in the treatment of prostatitis). The active substance of Vitaprost is prostaline - an extract of the prostate of bulls that have reached puberty. The substance is a complex of alkaline peptides (molecules composed of amino acid residues). The substance was synthesized in the 80s at the Military Medical Academy named after. Kirov (St. Petersburg). The rights to produce drugs based on it were obtained by MBNPK Cytomed (St. Petersburg). The first officially registered name is “Prostatilen”. This drug is officially registered as a remedy for the treatment of chronic prostatitis by Order of the Ministry of Health No. 329 of December 17, 1992, which means official recognition of the medicinal properties of prostaline.

Practicing dermatovenerologist Makarchuk Vyacheslav Vasilyevich about the drug “Prostatilen”: indications, administration, side effects, analogues

As a result of information leakage, other companies began to actively use prostaline in their production, which led to a number of lawsuits. Cytomed demanded that its competitors purchase a license.

Properties

Prostaline is a template substance that helps prostate cells stabilize their work according to its pattern (has an organotropic effect). The positive effects of drugs based on it are not limited only to the prostate. Basic properties:

• Normalization of lymph and blood circulation in the prostate, as a result of which swelling subsides and stagnation of secretions is eliminated;
• Increasing the number and improving the quality of sperm;
• Stimulation of sexual desire;
• Increasing the immune defense of cells;
• Regeneration of prostate tissue after damage (inflammation, surgery).

To achieve the effect, prostaline-based drugs must be taken in a course . They are prescribed for chronic prostatitis and cystitis, decreased fertility (to improve the quality of sperm when a woman is planning a pregnancy), to improve erectile function, and for the rehabilitation of the reproductive system after prostate surgery. Prostaline is also used to treat prostatic hyperplasia.

Have you ever had misfires in your sex life due to prostatitis?

The effectiveness of prostaline-based products

The website cytomed.ru published the results of joint studies of prostaline (in the form of rectal suppositories) conducted in 2011 by the VMA named after. Kirov and Dzhanelidze Research Institute. The target group was 24 men aged 21 to 41 years who suffered from chronic prostatitis and associated urinary disorders. There were no other diseases requiring constant medication.

Patients were administered 1 suppository with prostaline at night for 10 days, and also took multivitamin complexes. After the course of treatment, the condition of the prostate was monitored for another 90 days.

Based on the results of control tests, the pain syndrome decreased by 2.2 times, urination returned to normal (according to the results of uroflowmetry), and pathological nocturnal urges stopped . After monotherapy with prostaline, the iron acquired normal density, the lobes and sutures began to be palpated (swelling went away). The volume of the prostate decreased by 2 times . There was a pronounced positive trend in blood and urine parameters (no symptoms of an inflammatory process were observed).

Side effects of the drug and contraindications

Due to the fact that Vitaprost Plus is available in the form of rectal suppositories, its effect on the liver and kidneys, as well as on the gastrointestinal tract, is minimized.

The use of Vitaprost plus is not recommended for persons under eighteen years of age, as well as in the presence of severe damage to the nervous system. Individual intolerance is possible.

Vitaprost plus can be used for anal fissures and hemorrhoids. For these diseases, the drug helps relieve swelling and healing.

Side effects from taking the drug are associated with the action of the antibiotic included in the composition:

• headache, sleep disturbance, asthenia, depression, trembling of limbs, excessive nervousness, periodic convulsions;
• itching, urticaria, photophobia;

Side effects from taking the drug - headache, sleep disturbance, are associated with the action of the antibiotic

• dryness of the oral mucosa, diarrhea, enterocolitis, the appearance of plaque on the tongue, impaired taste;
• decreased blood pressure, cardiac arrhythmia, thromboembolism, worsening of cardiovascular diseases, tachycardia (increased heart rate), bradycardia (decreased heart rate);
• gastrointestinal bleeding, lymphadenopathy, thrombocytopenia;
• dysuria (impaired urination), polyuria (increased volume of urine produced), urethral bleeding, orchitis (inflammation of the testicle), epididymitis (inflammation of the epididymis), hematuria (presence of blood in the urine), urinary retention;
• vasculitis (inflammation of blood vessels), arthralgia (joint pain);
• shortness of breath, bronchospasm, cough;
• tinnitus, blurred vision, sweating, chills.

Of the above side effects, only diarrhea occurs quite often, so it is recommended to take probiotics from the first day of therapy to avoid negative reactions from the gastrointestinal tract. If you follow the dosage prescribed by your doctor, the likelihood of side effects is low.

Also in the instructions for use of the drug Vitaprost plus it is recommended to refrain from driving vehicles.

During treatment with Vitaprost Plus, it should be taken into account that when taking non-steroidal anti-inflammatory drugs, their toxicity increases with the drug, as does the effect of anticoagulants.

Forms of release of the drug "Vitaprost"

Vitaprost is produced by Nizhpharm JSC under the control of the Stada Arzneimittel AG group of companies. Available in the form of tablets and rectal suppositories:

1. Candles "Vitaprost plus". Each contains 100 mg of prostaline and 400 mg of lomefloxacin hydrochloride (an antibiotic). Prescribed for acute and chronic bacterial prostatitis. Price 1575 rub. for 10 pcs.
2. Candles "Vitaprost Forte". It contains only prostaline (100 mg per suppository) and excipients. The price of candles for 10 pieces is 1232 rubles.
3. Vitaprost candles. Each contains 50 mg of prostaline. Price from 1000 rub. for 10 pcs.
4. Vitaprost tablets (more tablets for prostatitis): bluish or blue in color, inclusions are possible. Each contains 100 mg of prostaline (or 20 mg of peptides). Tablets of 10 pieces are packed in blisters. Packaged 2 per box. A package of tablets (20 pieces) costs from 1,248 rubles.

Forms of release of the drug "Vitaprost"

Suppositories are considered more effective because the active substance is absorbed almost directly into the prostate (it is next to the rectum). All drugs can be bought in regular pharmacies or ordered through online services .

VITAPROST PLUS candles

Drug: VITAPROST® PLUS (VITAPROST PLUS)

Active substance: lomefloxacin ATC code: G04BX KFG: A drug with antibacterial and anti-inflammatory effects used for diseases of the prostate gland ICD-10 codes (indications): N41 Reg. number: LSR-002821/07 Registration date: 09/20/07 Owner of reg. credential: NIZHFARM (Russia)

DOSAGE FORM, COMPOSITION AND PACKAGING

? Rectal suppositories from white or almost white to light cream with a grayish tint, torpedo-shaped.

Excipients: solid fat (vitepsol).

5 pieces.
— cellular contour packages (1) — cardboard packs. 5 pieces. — contour cell packaging (2) — cardboard packs. INSTRUCTIONS FOR USE FOR SPECIALISTS.
The description of the drug was approved by the manufacturer in 2013. PHARMACOLOGICAL ACTION

A combined drug with antibacterial and anti-inflammatory effects, used for prostate diseases.

Lomefloxacin is a broad-spectrum bactericidal agent from the group of fluoroquinolones. It affects the bacterial enzyme DNA gyrase, which ensures DNA supercoiling, forms a complex with its tetramer (A2B2 gyrase subunits) and disrupts the transcription and replication of DNA, leading to the death of the microbial cell.

Highly active against gram-negative aerobic microorganisms: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Citrobacter diversus, Klebsiella pneumoniae, Enterobacter cloacae, Proteus vulgaris, Salmonella spp., Shigella spp., Moraxella morganii, Haemophilus influenzae, Haemophilus parainfluenzae, Pseudomonas aeruginosa, Leg ionella pneumophila.

Moderately sensitive to the drug Staphylococcus aureus, Staphylococcus epidermidis, Serratia liquifaciens, Serratia marcescens, Mycobacterium tuberculosis, Chlamydia trachomatis, Hafnia alvei, Citrobacter freundii, Aeromonas hydrophila, Proteus mirabilis, Proteus stuartii, Providencia rettgeri, Providencia alcalifaciens, Kle bsiella oxytoca, Klebsiella ozaenae, Enterobacter aerogenes, Enterobacter agglomerans.

Streptococcus spp., Pseudomonas cepacia, Ureaplasma urealyticum, Treponema pallidum, Mycoplasma hominis and anaerobic bacteria are resistant to the drug.

Lomefloxacin acts on most microorganisms in low concentrations (the concentration required to inhibit the growth of 90% of strains, usually no more than 1 μg/ml). Resistance rarely develops.

The Samprost substance has an organotropic effect on the prostate. Reduces the degree of edema, leukocyte infiltration of the prostate gland, normalizes the secretory function of epithelial cells, increases the number of lecithin grains in the secretion of the acini, stimulates the muscle tone of the bladder. Reduces thrombus formation, has antiplatelet activity, and prevents the development of venule thrombosis in the prostate gland. Normalizes prostate and ejaculate parameters. Reduces pain and discomfort, improves copulatory function.

PHARMACOKINETICS

Data on the pharmacokinetics of Vitaprost® Plus are not provided.

INDICATIONS

— acute and chronic bacterial prostatitis caused by sensitive microorganisms (including those accompanied by inflammatory diseases of the genitourinary tract);

— conditions before and after surgery on the prostate gland.

DOSING REGIME

The drug should be used rectally, 1 suppository (suppository) 1 time/day after an enema or spontaneous bowel movement.

Before use, the suppository should be removed from the blister pack. After administration of the drug, the patient should remain in bed for 30-40 minutes.

The course of treatment continues until the pathogen disappears in the prostate secretion and ranges from 10 to 30 days (individually for each patient).

SIDE EFFECT

Side effects of the drug Vitaprost® Plus are associated with the presence of lomefloxacin in its composition.

Allergic reactions: skin itching, urticaria, photosensitivity, malignant exudative erythema (Stevens-Johnson syndrome).

From the side of the central nervous system: asthenia, dizziness, nervousness, anxiety.

From the digestive system: pseudomembranous enterocolitis, dysbacteriosis, increased activity of liver transaminases.

From the hematopoietic system and hemostasis system: bleeding from the gastrointestinal tract, thrombocytopenia, increased fibrinolysis, lymphadenopathy.

From the cardiovascular system: decreased blood pressure, rhythm disturbances, myocardiopathy.

The Samprost substance (prostate extract) rarely causes allergic reactions.

CONTRAINDICATIONS

- childhood and adolescence up to 18 years (the period of formation and growth of the skeleton);

- hypersensitivity to the components of the drug.

The drug should be used with caution in cerebral atherosclerosis, epilepsy and other diseases of the central nervous system with epileptic syndrome.

PREGNANCY AND LACTATION

The drug is not used in women.

SPECIAL INSTRUCTIONS

In case of cirrhosis of the liver, no adjustment of the dosage regimen is required (provided that renal function is normal).

During the treatment period, prolonged exposure to sunlight and the use of artificial ultraviolet radiation should be avoided.

At the first signs of photosensitivity (including increased skin sensitivity, burns, hyperemia, swelling, blistering, rash, itching, dermatitis), hypersensitivity, manifestations of neurotoxicity (including agitation, convulsions, tremor, photophobia, confusion , toxic psychoses, hallucinations) therapy should be discontinued.

Impact on the ability to drive vehicles and operate machinery

During the treatment period, patients must be careful when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

OVERDOSE

Data on drug overdose are not provided.

DRUG INTERACTIONS

With simultaneous use, the activity of oral anticoagulants increases and the toxicity of NSAIDs increases.

Drugs that block tubular secretion slow down the elimination of the drug.

There is no cross-resistance with penicillins, cephalosporins, aminoglycosides, co-trimoxazole, metronidazole.

CONDITIONS OF VACATION FROM PHARMACIES

The drug is approved for use as a means of OTC.

CONDITIONS AND DURATION OF STORAGE

List B. The drug should be stored out of the reach of children at a temperature not exceeding 20°C. Shelf life: 2 years.

Reception mode

Take two tablets daily, no matter before or after meals. For prostate hyperplasia, the course will be at least a month, for chronic inflammation of the gland - from 10 days. During remissions of chronic prostatitis (to prevent exacerbations), Vitaprost is taken 2 tablets daily for a month, then take a break. 1-2 courses per year are enough.

Rectal suppositories "Vitaprost Plus" are administered once a day. The intestines must first be cleansed naturally or forcibly. After treatment, it is advisable to lie down for about half an hour. The course is at least 10 days.

Vitaprost suppositories (without antibiotics) are used for chronic prostatitis in a course of 10 days, for hyperplasia - from 15 days, to eliminate the symptoms of an overactive bladder (frequent urination, incontinence due to irritation) - from 20 days.

Purpose of the drug

The drug is prescribed for the treatment of diseases associated with the male genitourinary system. It is also used to prevent prostate-related diseases. The suppositories have a natural composition and are available without a prescription, but it is better to consult a doctor before use.

Vitaprost Plus is a suppository that is prescribed for chronic or acute bacterial prostatitis. They are necessary after surgery on the prostate gland. This drug is also suitable for the treatment of inflammatory processes in the genitourinary tract. Due to the unique composition, the suppositories effectively cope with inflammatory processes in the gland area. During clinical studies, it was possible to prove that the drug copes with microorganisms that cause pathologies.

After starting treatment with the drug, ejaculation and prostate function normalize.

Vitaprost Plus is available in the form of suppositories, which differ in cream or white shade. Usually doctors prescribe one suppository per day. The dosage is increased or decreased depending on the case. It is better to consult a doctor for an appointment. The duration of treatment depends on the complexity of the disease. Taking the drugs lasts from 10 days to a month .

​

Contraindications, side effects

Of the contraindications to the use of suppositories, the instructions indicate only individual intolerance. For tablets:

• Deficiency of lactase and isomaltase in the body;
• Individual intolerance to fructose, sucrose;
• Glucose-galactose malabsorption (improper absorption of these substances).

Vitaprost Plus suppositories should not be used by men with epilepsy and other disorders of the central nervous system, cerebral atherosclerosis . Side effects caused by the presence of antibiotics:

1. Rash and other skin irritations.
2. Dizziness, anxiety, headaches, fatigue, shortness of breath, blurred vision.
3. Constipation, diarrhea, impaired taste perception, possibly intestinal bleeding.
4. Decreased blood pressure, arrhythmia.
5. Chills, thirst.

Other Vitaprost drugs, except for an allergic reaction caused by individual intolerance, have no side effects. They do not interact with medications. There are no known cases of Vitaprost overdose. The drug is theoretically compatible with alcohol, but in fact, taking ethanol makes treatment pointless.

special instructions

• The use of Vitaprost Plus for liver cirrhosis does not differ from the standard treatment regimen in cases where there are no dysfunctions of this organ.
• Taking Vitaprost Plus is not a limitation for activities that require increased concentration and high speed of psychomotor reactions. This also applies to driving a car. Caution is advised.

During the therapy period, prolonged exposure to sunlight, as well as visiting a solarium, are not recommended. Exposure to ultraviolet rays can provoke the development of photosensitivity, expressed by the following symptoms:

1. hypersensitivity of the epidermis;
2. sunburn;
3. hyperemia;
4. swelling;
5. the formation of blisters, dermatitis and other undesirable manifestations on the surface of the skin;
6. itching

Comparative analysis with some drugs

Differences and similarities between Vitaprost and other drugs for the treatment of prostatitis:

• "Prostamol Uno" is an extract of dwarf palm fruit. Just like Vitaprost, it helps reduce swelling of the gland. The effectiveness has been clinically proven (https://www.rmj.ru/articles/urologiya/Opyt_primeneniya_preparata_Prostamol_Uno_v_Rossii_pri_lechenii_dobrokachestvennoy_giperplazii_predstatelynoy_ghelezy_i_hronicheskogo_prostatita/). But the course is longer, and the result is less pronounced ;
• “Afala” is a homeopathic remedy based on antibodies to prostate-specific antigen isolated from bovine prostate extract. The action is similar to Vitaprost (its analogue ). The course is long - 16 weeks. The effectiveness has been clinically proven (https://urologyjournal.ru/ru/archive/article/11569).

Drug “Afala”

• "Prostacor" - injections based on prostate extract, generic drug "Vitaprosta" (same active ingredients). Generics are also “Prostatilen”, “Prostalin” and “Prostanorm”.
• “Longidase” is a rectal suppository based on bovhyaluronidase azoximer. The substance relieves inflammation and softens scar tissue. Prevents sclerosis of gland tissue, alleviates the symptoms of chronic prostatitis (https://umedp.ru/articles/longidaza_v_kompleksnoy_terapii_khronicheskogo_prostatita.html).

Read about the Acutest device for the treatment of prostatitis - review, effectiveness, contraindications.

Preparations based on prostaline (Vitaprost) are more convenient because the course of treatment is much shorter and the range of areas of influence on the genitourinary system is wider.

Doctors' opinion

Doctors recognize the effectiveness of the Vitaprost series of drugs for treating chronic prostatitis and improving the functioning of the male genitourinary system. As monotherapy, it is prescribed during remissions to prevent relapses. In acute prostatitis, drugs (except Vitaprost Plus) are used as auxiliary drugs (they do not conflict with antibiotics).

The effectiveness of prostaline-based drugs has been clinically proven, which gives doctors every right to prescribe it to their patients. The main condition for effectiveness is a correct diagnosis.

Reviews of dermatovenerologist Vyacheslav Vasilyevich Makarchuk about the drug “Vitaprost”

Vitaprost Plus description and instructions for use of the drug.

Drug name:

Vitaprost Plus

Release form, composition and pack

Rectal suppositories from white or almost white to light cream with a grayish tint, torpedo-shaped. 1 sup. Samprost substance (based on 20% content of water-soluble peptides) 100 mg lomefloxacin hydrochloride 400 mg. Excipients: vitepsol.

Clinical and pharmacological group: A drug with antibacterial and anti-inflammatory effects, used for diseases of the prostate gland.

pharmachologic effect

A combined product with antibacterial and anti-inflammatory effects, used for prostate diseases.

Lomefloxacin is a broad-spectrum bactericidal agent from the group of fluoroquinolones. It affects the bacterial enzyme DNA gyrase, which ensures DNA supercoiling, forms a complex with its tetramer (A2B2 gyrase subunits) and disrupts the transcription and replication of DNA, leading to the death of the microbial cell. Highly active against gram-negative aerobic microorganisms: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Citrobacter diversus, Klebsiella pneumoniae, Enterobacter cloacae, Proteus vulgaris, Salmonella spp., Shigella spp., Moraxella morganii, Haemophilus influenzae, Haemophilus parainfluenzae, Legionella pneumophila. Moderately sensitive to the product Staphylococcus aureus, Staphylococcus epidermidis, Serratia liquifaciens, Serratia marcescens, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Chlamydia trachomatis, Hafnia alvei, Citrobacter freundii, Aeromonas hydrophila, Proteus mirabilis, Proteus stuartii, Providencia rettgeri, Providencia alcalifaciens, Klebsiella oxytoca, Klebsiella ozaenae, Enterobacter aerogenes, Enterobacter agglomerans. Streptococcus spp., Pseudomonas cepacia, Ureaplasma urealyticum, Treponema pallidum, Mycoplasma hominis and anaerobic bacteria are resistant to the product.

Tanakan - instructions, composition, dosage, side effects of use

Lomefloxacin acts on most microorganisms in low concentrations (the concentration required to inhibit the growth of 90% of strains, usually no more than 1 μg/ml). Resistance does not develop often. The Samprost substance has an organotropic effect on the prostate.

Reduces the degree of edema, leukocyte infiltration of the prostate gland, normalizes the secretory function of epithelial cells, increases the number of lecithin grains in the secretion of the acini, stimulates the muscle tone of the bladder. Reduces thrombus formation, has antiplatelet activity, and prevents the development of venule thrombosis in the prostate gland. Normalizes prostate and ejaculate parameters. Reduces pain and discomfort, improves copulatory function.

Pharmacokinetics

Data on the pharmacokinetics of the product are not provided.

Indications

• acute and chronic bacterial prostatitis caused by sensitive microorganisms (including those accompanied by inflammatory diseases of the genitourinary tract);
• conditions before and after surgery on the prostate gland.

Dosage regimen

The drug should be used rectally, 1 soup. 1 time/day after an enema or spontaneous bowel movement. Before use, the suppository should be removed from the blister pack. After administering the product, the patient should remain in bed for 30-40 minutes.

It is recommended to continue treatment until the pathogen disappears from the prostate secretion: from 10 to 30 days (individually for each patient).

Cimesol - Cimesolum - instructions, composition, dosage, side effects of use

Side effect

Side effects of the Vitaprost Plus product are associated with the presence of the antibiotic lomefloxacin in its composition.

• Regarding the central nervous system: asthenia, dizziness, nervousness, anxiety.
• Regarding the cardiovascular system: decreased blood pressure, rhythm disturbances, myocardiopathy.
• Regarding the digestive system: pseudomembranous enterocolitis, dysbacteriosis, increased activity of liver transaminases.
• Regarding the hematopoietic system: bleeding from the gastrointestinal tract, thrombocytopenia, increased fibrinolysis, lymphadenopathy.

Allergic reactions: skin itching, urticaria, photosensitivity, malignant exudative erythema (Steven-Johnson syndrome). The substance "Samprost" (prostate extract) rarely causes allergic reactions.

Contraindications

• childhood and adolescence up to 18 years (the period of formation and growth of the skeleton);
• high sensitivity to product components.

The product should be used with caution in case of cerebral atherosclerosis, epilepsy and other diseases of the central nervous system with epileptic syndrome.

Pregnancy and lactation

The drug is not used in women.

special instructions

In case of liver cirrhosis, no adjustment of the dosage regimen is required (if the condition of normal renal function is observed). During the therapy stage, prolonged exposure to sunlight and the use of artificial ultraviolet radiation should be avoided. At the first signs of photosensitivity (including increased skin sensitivity, burns, hyperemia, swelling, blistering, rash, itching, dermatitis), hypersensitivity, manifestations of neurotoxicity (including agitation, convulsions, tremor, photophobia, confusion , toxic psychoses, hallucinations) therapy should be discontinued.

Maverex description and instructions for use of the drug.

Impact on the ability to drive vehicles and operate machinery

at the therapy stage, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Overdose

Data on product overdose are not provided.

Drug interactions

With simultaneous use, the activity of oral anticoagulants increases and the toxicity of NSAIDs increases. Medicines that block tubular secretion slow down the excretion of the product. There is no cross-resistance with penicillins, cephalosporins, aminoglycosides, co-trimoxazole, metronidazole.

Storage conditions and periods

List B. The drug should be stored out of reach of children at a temperature not exceeding 20°C. Shelf life: 2 years.

Attention! To use the drug "Vitaprost Plus" you should obtain a detailed and complete consultation with your doctor. The instructions are provided solely for familiarization with “ Vitaprost Plus ”.

Sources of information: rsml.med.by, mednet.by, drugs.com, webmd.com.

Reviews from men

Pavel, 33 years old: “At first I took lomefloxacin tablets, but around the 5th day my pancreas started to hurt, then I decided to switch to Vitaprost Plus suppositories.” I put two at a time all week, but there was no improvement. Only blood began to appear from the anus due to irritation of the mucous membrane.”

Egor, 41 years old: “4 days after using Vitaprost Forte suppositories, the pain in the perineum went away. After 10 days (full course), the relapse of chronic prostatitis was completely stopped.”