Lactobacillus reuteri and simethicone in the treatment of intestinal colic in infants: a prospective randomized trial

When the abdomen swells, an air mass consisting of small gas bubbles forms inside it. They attach to the walls of the intestine, as if they “stick”, so their evacuation is difficult.

Can Simethicone help in this case? The instructions for use of this drug inform us that its effect on the intestines favors the process of removing gases naturally. Also, the drug "Simethicone" accelerates their absorption into the bloodstream. The purpose of this drug is to get rid of flatulence (bloating) in both adults and children, including newborns.

Features of drug use

How to use the medicine "Simethicone" correctly? Instructions for use recommend taking the product strictly as prescribed by the doctor. Under no circumstances should the dosage be exceeded.

It is prohibited to use it in case of allergic reactions to this drug. You should not use this medicine without consulting a doctor if you have severe intestinal or stomach disease.

The maximum effect from using the drug "Simethicone" can be achieved by taking it before going to bed or after eating. If bloating after regular use does not decrease, or even worsens, immediately seek help from a specialist.

It is necessary to understand that the drug only relieves flatulence, and not the cause of its occurrence. Therefore, in case of frequent manifestations of bloating, you should visit a doctor to identify factors that contribute to increased gas formation in the intestines.

Instructions for use

Each form of the drug has its own instructions, which contain dosage and methods of use, as well as age restrictions.

Drops

They are prescribed to be taken after eating food orally. The bottle should first be shaken to form a homogeneous emulsion.

In case of strong formation of gases and their accumulation in the gastrointestinal tract, the medicine is prescribed according to a specific schedule.

  1. From the 30th day of life until 24 months, they should be taken 8 drops 4 times in 24 hours.
  2. From 24 to 72 months they are prescribed 13-15 drops 4 times in 24 hours.
  3. From 72 months (6 years) and older they take 16 drops 4 times in 24 hours.

To ensure accurate drop collection, it is recommended to hold the bottle vertically, neck down.

To make it easier for small children to take the product, it can be mixed with a small amount of non-gas liquid, milk or formula.

After the symptoms subside, it is recommended to stop treatment.

To prepare for examinations, the drug must be taken 2 times in 24 hours in the dosage recommended by the doctor. They start drinking it a day before the procedure.

Capsules

This form is prescribed for severe gas formation. It is suitable for adults and children over 72 months (6 years). Simethicone capsules should be taken 2 units per 24 hours. They must be taken with the required amount of liquid without gases after eating and, if necessary, 30-40 minutes before bedtime. The duration of treatment is prescribed by the doctor based on the symptoms.

To prepare for examinations, take 2 capsules a day before the procedure. 3 times in 24 hours.

In case of poisoning (to exhibit an antifoaming effect), the product is used once. For adults, the dose is 10-20 capsules, for children 4-10 capsules. The exact amount will be prescribed by the doctor.

Pills

Instructions for use of tablets and capsules are similar. There are only small differences.

Simethicone tablets must be chewed thoroughly before swallowing. If necessary, they can be washed down with a sufficient amount of non-carbonated liquid.

Suspension

This form of the drug is added to newborn babies on artificial nutrition, adding 15 drops to the bottle at each feeding. The product mixes well with food.

Children from 12 months of age to 6 years of age are given the medicine before or during meals, 15 drops. Also, if necessary, you should give 15 drops of the suspension before going to bed.

From 6 years old, doctors prescribe 16-20 drops of Simethicone with fennel before or during meals every 5 hours.

The duration of therapy is determined by the attending doctor.

Before using the suspension, the bottle must be vigorously shaken.

Before examinations, the drug is prescribed by a doctor, prescribing the dosage and duration of use.

Forms of the drug and methods of their use

If you choose Simethicone tablets to get rid of flatulence, you must chew them before swallowing. The drug in the form of gelatin capsules must be swallowed whole. The medicine in liquid form should be consumed by measuring it with a specially designed measuring spoon (or cup). If it is not included in the kit, ask the pharmacist at the pharmacy to provide it. After each use, the measuring object should be rinsed with water and dried.

Liquid "Simethicone" can be mixed with milk formulas, juices, and water before use.

How to properly store the medication "Simethicone"? The instructions for use state that the drug should be kept at room temperature, in a dark and dry place.

Method of congestion and dosage

With flatulence

For children over 12 years of age and adults, take 1 tablet 3 times per dose.

Methods of preparation for diagnostic investigations

Prescribe 1 tablet 3 times per dose the day before the follow-up and 1 more tablet on the day of the follow-up. Simethicone tablets should be taken before or after the hour. The duration of the treatment course is determined individually. If necessary, the drug can be taken for three hours.

Extricated by our own means:

dosage depends on the severity of intoxication. The minimum recommended dose is 3 tablets.

Side effects

Can unpleasant consequences occur if you use Simethicone? Reviews from patients who have used this drug indicate that it is quite well absorbed and accepted by the body, without causing any traceable adverse reactions on its part.

If, after taking Simethicone, you experience difficulty breathing, swelling of the throat, face or tongue, red spots and itching on the skin, immediately call an ambulance.

Analogs

Analogues of Simethicone can also be used in the treatment of flatulence - drugs similar in action, for example:

  • Bobotik;
  • Meteospasmil;
  • Espumisan and a number of other drugs.

Despite what is written in the instructions for use of Simethicone, be sure to consult a doctor who will determine the cause of the pathology and, therefore, recommend adequate treatment.

The drug "Simethicone" for newborns: features of use

A fairly large number of children suffer from abdominal pain in the first months of their lives. Some parents are lucky and do not often think about the problem of gas formation in their children. In some children, flatulence disappears immediately after physical impact on the tummy (this can be a heated diaper or light massage movements). For others, the problem requires the use of a variety of medications. One of them is Simethicone.

The instructions for use explain in detail how to correctly use the drug in case of bloating in newborns and children under one year of age. To get rid of the problem of flatulence, in this case liquid “Simethicone” (suspension or emulsion) is used. Before giving the drug to your baby, the bottle of medication should be shaken well. The dose for single use is from 20 to 30 mg. The drug should be diluted with a small amount of breast milk or water. You can give the medicine to your child 3 to 5 times during the day.

Medicines containing simethicone list of medicines

The drug Simethicone is indicated for a number of pathologies and disorders of the gastrointestinal tract. It is mainly prescribed by doctors as an additional remedy that can help in the fight against the unpleasant symptoms that accompany the disease.

So, the remedy is indicated for the following conditions:

  • flatulence;
  • aerophagia;
  • increased gas formation after surgery;
  • gastrocardial syndrome;
  • Remgeld syndrome.

Simethicone is also prescribed in the following cases:

  • preparatory activities for ultrasound;
  • preparation for radiography;
  • preparation for sonography.

It is unacceptable to use Simethicone in the following cases:

  • intolerance to the main component, the presence of allergic reactions;
  • intestinal obstruction;
  • obstructive conditions of the gastrointestinal tract.

Self-administration of even such a harmless remedy as Simethicone is completely unacceptable. The frequency of administration and dosage should be determined by the attending physician.

Instructions for use

Since Simethicone is a suspension, it must be shaken thoroughly before each dose. If the bottle is stored in the refrigerator, it should be warmed to room temperature before use.

However, it is preferable to store the medicine in a dark, dry place. The patient should remember that the dosage and duration of taking the drug is determined by the doctor.

The rules for taking Simethicone are as follows:

  • the remedy is always taken after meals or before bedtime;
  • tablets should be chewed thoroughly and only then swallowed (does not apply to capsules);
  • suspension and drops can be mixed with water, tea, juice;
  • the product must not be frozen;
  • the drug in liquid form can be stored and used for no more than a month;
  • the drug must be taken at the same time.

Failure to comply with the rules for taking the drug Simethicone significantly reduces the effectiveness of the drug, slowing down the patient’s recovery.

Suspension dosage

  • Adults - 25-50 drops at a time.
  • Newborns - 10-15 drops per dose.
  • Children 6-15 years old - 10-20 drops per dose.
  • Teenagers - 20-50 drops per dose.

Drops

  • Adults - 25-50 drops per dose.
  • Newborns - 10 drops per dose.
  • Children - 10-15 drops per dose.
  • Teenagers - 20-50 drops per dose.

Simethicone with fennel from Evalar

Simethicone with fennel has a similar set of properties as the classic drug, but additionally has the following advantages:

  • relieves the general condition of bloating;
  • has antispasmodic and antiemetic effects;
  • prevents the formation of gases;
  • helps eliminate the problem in a purely natural way.

This product is absolutely natural, as it contains only Simethicone and fennel essential oil. Available in the form of soft gelatin capsules.

What is Simethicone with fennel

Simethicone with fennel from Evalar is a dietary supplement. It is not a medicine.

The product is available in soft capsules with a light yellow oily liquid. Contains semiticon - 80 mg, fennel essential oil - 5 mg, and also:

  • gelatin;
  • glycerol;
  • sorbitol syrup;
  • twin 80;
  • vegetable oil.

Simethicone is a chemical compound from the group of dimethylpolysiloxanes:

  1. Has a carminative and defoaming effect;
  2. Reduces the formation of gases in the intestines;
  3. Prevents their further education.

Simethicone is not absorbed into the gastrointestinal tract, but is excreted unchanged from the body. The substance does not have a negative effect on digestion, liver, kidney function, and does not interfere with the absorption of vitamins and minerals.

Fennel fruits have the following effects:

  • reduce gas formation;
  • eliminate spasms, pain, inflammation;
  • improve the functioning of the gastrointestinal tract;
  • stimulate appetite.

In addition, the plant has a weak diuretic effect on the body. In this supplement, fennel complements and enhances the effect of simethicone.

How to store

The bottle with medicinal contents should be stored in a closet. You should not put the drug in the refrigerator, since low temperatures reduce its effectiveness. Do not use a medicine that has expired, as this may lead to unforeseen consequences.

Simethicone is a safe medicine for infants, the action of which is aimed at eliminating increased gas formation. It is approved for use from the first weeks of life. The dosage, number of doses, and duration of therapy should be prescribed exclusively by the pediatrician, taking into account the characteristics of the baby’s body.

People with acute sensitivity to substances that are part of the product may experience an immediate or delayed allergy. If these manifestations occur, you should immediately stop taking the drug and consult a specialist for advice.

The instructions for Simethicone say that the emulsion does not contain sugar or its components, so the product is suitable for people with diabetes of any form.

When treating increased gas formation, you should refrain from drinking drinks with gas and foods that can provoke symptoms of bloating.

The use of this drug can distort the final results of some examinations, so you should warn your doctor.

The drug does not affect the speed of psychomotor reactions and perception of the situation, so it can be taken while driving a car.

Antareit antacid

Antareit is a complex drug, the action of which is based on its constituent components:

  1. Magaldrate (aluminum magnesium hydroxide sulfate) inactivates hydrochloric acid in gastric juice. It does not cause secondary hypersecretion of HCl and binds bile acids. The compound also has an enveloping effect, as it forms a protective layer on the surface of the gastric mucosa. This protects it from damage.
  2. Simethicone reduces the surface tension of gas bubbles in the intestines, causing them to collapse. In this case, gases can be excreted naturally or absorbed by the intestinal mucosa.

The remedy can be used for any type of dyspepsia (due to both disease and nutritional disorders).

Not recommended:

  • children under 12 years old;
  • during pregnancy;
  • with renal failure;
  • intolerance to fructose and other components of Antareit.

In pharmacies, the product is found only in the form of chewable tablets (made in India).

Do not exceed the dose of the medicine indicated in the instructions supplied with the drug, which is appropriate for the age of the person who will take the medicine. Do not take Simethicone if you are allergic to this substance.

If you suffer from severe diseases of the stomach and intestines, be sure to consult your doctor before starting to take Simethicone.

The maximum effectiveness of Simethicone is observed when taken after meals and before bedtime.

Simethicone only relieves bloating, but does not eliminate its immediate cause.

Source: https://blotos.ru/simetikon-instrukcia-po-primeneniu

Negative consequences

Since the most common remedy used by parents in such cases is Espumisan, the question immediately arises: which drug is more effective? Both drugs have almost the same effect. The difference between Simethicone and Espumisan is only in concentration. The latter has more.

You can continue using the drug "Simethicone" to treat a child for more than one week. Another question that worries parents is: are there any side effects from the drug? The drug "Simethicone" for newborns is absolutely safe. Of course, like any other drug, it can cause an allergic reaction in the child in the form of rashes. But it goes away pretty quickly.

Simethicone - a carminative drug for bloating

Increased gas formation is an unpleasant phenomenon familiar to every person after eating certain foods.

But flatulence is also caused by various pathologies that can pose a danger to the body, for example, after operations.

In all situations where excessive gas formation creates discomfort, medications are taken to eliminate it. One of the most effective means for this purpose is Simethicone.

Instructions for use

The active substance of the drug directly affects the surface tension of the liquid bubbles, causing bloating, after which they burst.

The nature of their formation is associated with the abuse of food with an excessive carbohydrate content. For this reason, the intestinal lumen becomes clogged with undigested proteins, which create a dispersed system for the formation of bubbles.

The released gases are released naturally without any discomfort . Taking the drug reduces the ability to form new bubbles due to changes in the properties of the liquid at the boundary of two different phases.

Simethicone is not absorbed by the intestinal walls, which makes its use completely safe.

Indications

Prescribing Simethicone is advisable in the following cases:

  • Manifestations of flatulence, including those that are a consequence of surgery;
  • Conditions of aerophagia, when air is swallowed along with food intake;
  • When diagnosing gastrocardial syndrome;
  • As an element of preparation for radiography, endoscopy, ultrasound or sonography;
  • After poisoning with compounds that have surface-active properties.

During clinical trials, it was observed that the drug has a protective effect on the gastric mucosa, reducing the effect of organic acids, acetylsalicylic and hydrochloric acid on it.

It also has the property of suppressing the activity of certain pathological microorganisms, and can be used in the complex treatment of gastric diseases.

Mode of application

Simethicone is taken in doses, at the appointed time, and for a certain period of time according to the doctor’s recommendations. Depending on the formulation, the rules of administration are as follows:

  • The drug is taken before bedtime or after meals;
  • Capsules are swallowed whole without chewing;
  • The tablets must be chewed during administration;
  • The liquid form is dosed with special measuring instruments included with the medicine;
  • The liquid form can be mixed with liquid food products;
  • The liquid form should not be frozen or stored for more than 30 days after opening.

The dosage of the medicine is affected by the patient’s age and indications, as well as the concentration of the active substance in it. For medicinal purposes, adults take 20-50 drops, 1-2 capsules or one tablet per dose.

For infants, a suspension or drops is used . Before taking, the drug is shaken, and the required amount is dosed with a measuring device, and mixed with water or breast milk. A single dose should not be higher than 50 mg, and the maximum permissible daily number of doses should not be more than five.

Release form

Simecticon is available in various easy-to-use forms:

  • Emulsion 40 or 100 mg/ml in vials of 30 or 50 ml;
  • Capsules 40 mg;
  • Susp. 40 mg/ml in vials of 30, 50, 75, 100 ml;
  • Susp. 66.6 mg/ml in a 30 ml vial;
  • Tablets 80 and 125 mg.

Interaction with other drugs

The active ingredient Simecticon is incompatible with the simultaneous use of certain drugs:

  • Its simultaneous use with antacids that neutralize hydrochloric acid in the secretion of gastric juice is unacceptable;
  • It is undesirable to use it together with Hydrochlorothiazide and Fosinopril, as this reduces their absorption. The interval before the next dose should be more than two hours;
  • Co-administration with Ribaverine reduces the availability of the latter.

Simethicone is also used in combination with other compounds as components of medications:

  • Simethicone with Loperamide is the drug Imodium plus;
  • Simethicone with magnesium hydroxide and algedrate is Almagel neo;
  • Simethicone with alverine citrate is Meteospasmil.

Side effects

Simethicone is chemically neutral and does not have any side effects on organs and systems, except for rare allergic reactions after taking it in the form of redness of the skin, difficulty breathing, itching, swelling of the throat, lips and tongue.

Despite the low absorption properties and the classification of the medicine as safe, if the permissible dosage is exceeded, you should consult a specialist.

During pregnancy

Due to its inert properties and isolated cases of side effects, Simecticon is prescribed, if necessary, to pregnant women, as well as during the entire period of lactation.

Storage conditions and periods

The drug should be stored in a dark place, at a temperature not exceeding 25°C for two years. Opened packaging is stored under the same conditions for no more than a month. Keep away from children!

Price

The cost of the drug depends on the manufacturer, the country in which it is sold, and the value of the pharmacy chain’s trade markup.

  • The average price in Russia is from 160 to 490 rubles;
  • The average cost in Ukraine is from 119 to 514 UAH.

Analogs

There are several manufacturers of drugs that produce their own brands with the substance Simethicone, but have different names, these are:

Flatulence. What is flatulence?

A clear example of efficiency

If you doubt that Simethicone is really effective, do a simple experiment at home.

  1. Take a small transparent container (shot glass, glass, jar) and pour plain cold water into it.
  2. Add the detergent you use to wash dishes (for example, Fairy or similar) into the container.
  3. Shake the contents until a large number of small bubbles (foam) form.
  4. Now add a couple of drops of the drug and mix everything again.
  5. As a result, the foam disappears completely. In the same way, under the influence of the drug, gas bubbles in the intestines unite and exit.

Indications

Increased gas formation and accumulation of gases in the gastrointestinal tract (flatulence, Remgeld syndrome, aerophagia, gas formation in the postoperative period); preparation for diagnostic procedures of the abdominal cavity and pelvic organs (radiography, sonography), prevention of foam formation during gastroscopy; as an antifoam agent for poisoning with surfactants (for example, detergents).

Does not contain sugar, can be used by patients with diabetes and digestive disorders.

Use for colic in children

Clinical studies show that the use of simethicone does not improve infantile colic and colic in children[1][2] (no different in effectiveness from placebo in systematic reviews)[3],[4] and therefore its use for this purpose is unjustified.

Contraindications

Hypersensitivity, intestinal obstruction, obstructive diseases of the gastrointestinal tract.

Customer reviews about the biogenic dietary supplement Simethicone with fennel

Konstantin, 46 years old

I recently had severe bloating and pain in my stomach. Capsules with fennel extract came to the rescue. The herbal remedy quickly stabilized the condition and normalized digestion.

Elena, 53 years old

After heavy meals I take the natural drug Simethicone. It relieves spasms, a feeling of heaviness, improves the absorption of beneficial minerals and activates the production of vitamins.

Roman, 26 years old

My gastroenterologist prescribed a new dietary supplement, Simethicone. I have been suffering from gastritis for many years, and this is the best remedy to relieve flatulence, turbulence in the stomach, and acute cramps. I tried other supplements before, but they were not effective.

Yulia, 35 years old

I recently went on a diet. As a result, it only undermined the functioning of the gastrointestinal tract. She was restored with the help of the herbal drug Simethicone. It improved the digestive process, relieved attacks of nausea, colic and diarrhea.

pharmachologic effect

The pharmacological properties of Simethicone are characterized as antifoaming and carminative. By its action, the product can reduce the formation of gas and foam in the digestive tract. The substance is characterized by inertness and surface activity. Non-toxic.

By eliminating surface tension, Simethicone collapses gas bubbles that arise during the development of flatulence and prevents the formation of new ones. The gas that is released can be removed from the body naturally or absorbed in the intestines. The patient does not feel discomfort due to the effects of the drug.

After oral administration, Simethicone is practically not absorbed from the digestive tract and is excreted invariably.

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