- Description and release form
- Composition and mechanism of action
- Indications for use
- Instructions for children (dosage)
- Side effects and special instructions Are there any side effects?
- Contraindications for Cefekon
- Overdose
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Children's Cefekon has an analgesic and antipyretic effect . In the central nervous system, the drug causes a blockade of cyclooxygenase, thereby affecting the pain center and thermoregulation system. At the site of inflammation, the effect of paracetamol on cyclooxygenase is neutralized by cell peroxidase, which significantly reduces the anti-inflammatory effect. Cefekon does not negatively affect the gastrointestinal mucosa and water-electrolyte metabolism, that is, sodium water retention in the body is not observed.
Pharmacokinetics
The drug has high absorption and is quickly absorbed through the mucous membrane. Easily overcomes the BBB. Has high bioavailability. Distributed mainly in body fluids. Protein binding is insignificant (less than 10%). Metabolized in the liver. The maximum concentration of the drug in the blood occurs within 10-60 minutes after taking it. It is excreted by the kidneys in the form of inactive metabolites (sulfates and glucuronides).
Indications for use
The drug is prescribed to children as:
- antipyretic . Prescribed for influenza , ARVI , post-vaccination reactions, childhood infections and other conditions that cause an increase in body temperature;
- analgesics and for pain syndrome ( neuralgia , myalgia , headache and toothache, pain from burns and injuries).
Contraindications
Children under 1 month, hypersensitivity to paracetamol, chronic alcoholism. The drug should be prescribed with caution in diseases of the blood system, severe and liver dysfunction , genetically determined enzymatic absence of glucose-6-phosphate dehydrogenase.
Cefekon D - suppositories during pregnancy and lactation can be prescribed taking into account the benefits and risks for the pregnant woman and the child (fetus). Studies have not established the teratogenic, mutagenic and embryotoxic effects of paracetamol .
How to store Cefekon at home
Cefekon N is stored at a temperature not exceeding 25 °C in a place protected from sunlight. The storage temperature of Tsefekon D should be no more than 20 °C. The slight difference in the permissible storage temperature is due to the fact that paracetamol, which is part of Cefekon D, is more susceptible to high temperatures.
Suppositories can be stored in a special medicine cabinet in a dark place, but it is better to place them in a special compartment in the refrigerator door.
When opening the package, it is advisable to indicate the date of opening. But this is optional. If the package is accidentally opened, do not use the drug for more than 24 hours.
Do not store suppositories:
- near heating devices;
- in a place accessible to children;
- in the closet or on the balcony;
- on the windowsill.
Analogs of Cefekon:
- Efferalgan;
- Paracetamol;
- Panadol;
- Tylenol;
- Perfalgan;
- Lupocet;
- Aldorol;
- Ifimol;
- Piaron.
Instructions for Cefekon D
The suppository is administered rectally to the child or adolescent. The instructions for Cefekon D suppositories for children recommend administering the suppositories after a cleansing enema. The suppository is administered 2-3 times a day. A single dose of Cefekon D on average should not exceed 15 mg per kilogram of a child’s weight, and the maximum daily dose is 60 mg.
A special purpose of the drug is required for children aged 1-3 months - a single administration of one suppository (0.05 g of paracetamol) per day.
At the age of 3 months to one year, with a child weighing 6-10 kg, the dose of the drug is 1-2 suppositories of 0.1 g each; 1–3 years with a body weight of 10–15 kg 1–2 suppositories of 0.1 g; 3–10 years (weight 16–32 kg) 1 candle, 0.25 g; 10–12 years (weight 33–36 kg) 2 suppositories of 0.25 g each.
Tsefekon - suppositories for children, the instructions do not recommend using for a long time. Taking Cefekon D to reduce fever is limited to 3 days, and to relieve pain - use no more than five days.
Release form and composition
Cefekon D is produced in the form of white, creamy-white or yellowish-white suppositories, torpedo-shaped. The drug is intended for rectal use in the treatment of children.
1 suppository weighing 1.25 g contains:
- active ingredient: paracetamol – 250, 100 or 50 mg;
- excipient: solid fat (supposir, vitepsol).
The drug is packaged in blister packs containing 5 suppositories. There are 2 blisters in 1 cardboard box.
Analogs
Level 4 ATC code matches:
Phenacetin
Combiflu
Chlorphenamine
Coldflu
Calpol
Fervex
Panadol Extra
Panadol for children
Panadol
Solpadeine
Efferalgan
Milistan
Coldrex Maxgripp
Coldrex Hotrem
Coldrex
AntiGrippin
Unispaz
Pentalgin Plus
Rapidol
Maxicold
There are quite a lot of analogues of the drug “children’s Cefekon” containing paracetamol.
Let's mention just a few of them: Paracetamol for children , Children's Panadol , Tylenol for children , Bindard (effervescent powder for children), Dynafed EX , Volpan (powder), Dynafed junior , Dafalgan , Deminofen , Calpol 6 plus , Paracetamol MS , Efferalgan and others.
Reviews of Tsefekon D
On numerous online forums discussing drugs for children, reviews of Cefekon suppositories confirm the high effectiveness of the drug. Cefekon D is especially indispensable in cases where the child categorically refuses to take antipyretics and painkillers in the form of drinks (syrups) or tablets, or the child begins vomiting after taking the syrup.
Some parents, if their child has a fever, give him an antibiotic , which absolutely cannot be done without consulting a doctor. Do not forget that temperature is a protective reaction of the body and does not need to be reduced within moderate limits. Give your child wet wipes and give him plenty of fluids.
Antipyretic suppositories Tsefekon for children are the best option, but we should not forget that children’s suppositories for fever should not be taken for more than 3-5 days. In addition, the drug is not expensive. Information from forums confirms that suppositories for children containing paracetamol are quite popular among parents. People often ask on forums “how long does it take for Cefekon D suppositories to work?” As a rule, the effect appears within 15-20 minutes and lasts up to five hours.
Some parents are faced with the choice “which is better: Cefekon or Nurofen ?” and is it possible to give Cefekon and Nurofen to a child at the same time? These two drugs have different active substances ( paracetamol and ibuprofen ). Everything here is individual. In some cases, Cefekon is more effective, in others - Nurofen. It is not recommended to give Cefekons Nurofen at the same time. If between taking, for example, Nurofen, the temperature rises, reduce it by rubbing it. However, if your child takes Cefekon for five days and the temperature does not drop, then Cefekon must be replaced with another drug. But you cannot give your child one drug between doses of another.
Sometimes parents use adult suppositories to reduce their child's temperature. This cannot be done, since most parents cannot correctly calculate the dose for the child. It is better to use a drug intended for children.
Content
- Composition of Tsefekon suppositories
- Indications for the use of Tsefekon suppositories
- Dosage and instructions for use
Today, all pharmacies stock a huge number of antipyretic rectal medications for children. Among them, the most effective and safe are Cefekon temperature suppositories. They consist of paracetamol, which is why they not only quickly reduce the baby’s temperature, but also eliminate pain. Another advantage of Tsefekon suppositories for children is their affordable price range. In this article we will talk about the composition, dosage and use of these rectal suppositories.
Price Tsefekon D, where to buy
The price of Tsefekon suppositories for children 0.25 g No. 10 varies between 44 - 58 rubles per package. The price of Tsefekon D suppositories 0.05 g No. 10 is 34-42 rubles, and 0.1 g No. 10 is 38-47 rubles per package. You can purchase the drug in most pharmacies in Moscow and other cities.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Cefekon D rectal suppositories.
50 mg 10 pcs. Nizhpharm OJSC 42 rub. order - Cefekon D rectal suppositories. 250 mg 10 pcs. JSC "Nizhpharm"
58 RUR order
- Cefekon D rectal suppositories. 100 mg 10 pcs. JSC "Nizhpharm"
51 RUR order
Pharmacy Dialogue
- Cefekon D (supp. 50 mg No. 10)Nizhpharm JSC
37 RUR order
- Cefekon D (supp. 250 mg No. 10)Nizhpharm JSC
63 RUR order
- Cefekon D (supp. 100 mg No. 10)Nizhpharm JSC
50 rub. order
Europharm* 4% discount using promo code medside11
- Tsefekon d 0.25g suppositories 10 for childrenNizhpharm OJSC
65 rub. order
- Tsefekon d 0.05 10 suppNizhpharm JSC
42 RUR order
- Cefekon d 0.1g suppositories 10 for children JSC Nizhpharm
49 RUR order
show more
Pharmacy24
- Cefekon D for children 0.25 g N10 suppositories VAT "Nizhpharm", Nizhny Novgorod, Russian Federation
39 UAH. order - Cefekon D for children 0.1 g No. 10 suppositories VAT "Nizhpharm", Nizhny Novgorod, Russian Federation
45 UAH order
PaniPharmacy
- Cefekon D suppository Supp. cefekon D 0.25g No. 10 Russia, Nizhpharm
41 UAH order
- Cefekon D suppository Supp. cefekon D 0.1g No. 10 Russia, Nizhpharm
48 UAH order
show more
Rules for storing the drug Cefekon in pharmacies and clinics
According to the order of the Ministry of Health and Social Development of the Russian Federation N 706n “On approval of the Rules for the storage of medicines”, Tsefekon N and D suppositories are stored:
- in refrigeration chambers while maintaining the required temperature;
- near analogues and generics;
- in sealed packaging;
- at a humidity of no more than 70%.
Reciting from SanPinN 2.1.7.2790-10, if expired or falsified drugs are detected, they must be disposed of. In a pharmacy, Tsefekon is given heat treatment and then disposed of. Large quantities of illiquid goods are destroyed at special sites of pharmaceutical companies.
Tsefekon N and D must be transported in special refrigerated chambers to maintain proper storage conditions. Carriers are required to have a license and permit to transport drugs. This is regulated by Federal Law N61 “On the Circulation of Medicines” dated April 12, 2010.
Pharmacists and clinic staff are required to ensure proper storage of medications. Failure to promptly dispose of expired medications may result in a fine, while sale and use in hospitals may result in a suspended sentence.
