Dolobene gel: instructions for use

Treatment of diseases of the musculoskeletal system includes the use of drugs in various dosage forms. The form of ointments and gels for joints and muscles has the fewest side effects and a convenient method of use.

Using external dosage forms is simple, and their effect is often comparable to that of tablets. It is only important to choose the right remedy that can have the desired effect.

Dolobene gel has long been known for its therapeutic properties. The peculiarity of the drug is the combination of three active components at once, which complement and enhance each other’s effect.

Main components of the medicine

Doloben contains heparin. This substance is an anticoagulant. Heparin reduces blood viscosity. This substance is endowed with anti-inflammatory properties. Heparin helps fight such unfavorable manifestations of various diseases as swelling, redness, and discomfort in the joints.

The gel contains the active ingredient dexpanthenol. It helps increase the elasticity of connective tissue.

Dimethyl sulfoxide, which is part of the drug, neutralizes the negative effects of hydroxyl radicals that occur at the site of the inflammatory process, reduces vascular permeability in the affected area, and helps reduce sensitivity to pain.

The gel also contains auxiliary components:

polyacrylic acid. It acts as a thickener and gives the medication the desired consistency;
trometamol This substance helps facilitate the absorption of other active components of the product;
isopropanol Alcohol has a pronounced disinfecting effect;
oil obtained from rosemary. The substance has an antibacterial effect;
citronella oil. The substance is endowed with disinfecting properties. When used externally, medicinal oil prevents infection from penetrating into affected tissues.

Compound

"Dolobene" is a complex action product, recognized as one of the best topical preparations on the modern market.

Due to the special composition of the medicine, its use serves several purposes simultaneously, and the pain goes away in a short time. So, Dolobene contains the following substances:

Heparin sodium - 100 g of medicine contains 50,000 IU. The substance acts on the texture of the blood, slowing down its clotting. Due to this, it is possible to relieve acute and sluggish inflammation. Tissue regeneration is additionally accelerated.
Dimethyl sulfoxide (90%) – contains 16.66 g per 100 g of cream. The component quickly acts on the source of inflammation, inhibiting it exactly where it is needed. Due to this, an analgesic effect is achieved. An additional effect is increased activity and improved absorption of other drug substances.
Dexpanthenol - the gel contains 2.5 g of active ingredient. A derivative of vitamin B3 is converted into pantothenic acid as soon as it enters the skin. This substance enhances metabolism, due to which all processes are activated, including accelerating the restoration of damaged tissues.

Dolobene also contains additional substances that give it a viscous texture, extend shelf life and enhance the effect of other components.

Among them: purified water, mountain pine oil, polyacrylic acid . The gel is sold without a prescription, but it is advisable to use it after consultation with a doctor who understands the disease picture of a particular patient.

Release form and pharmacological effects

The medication is produced in the form of a gel. In the photo of the medicine you can see that it is colored transparent or yellowish. The gel, which has a thick consistency, is packaged in small tubes with a pointed tip on the outside of the lid.

The drug is endowed with anti-edematous and anesthetic properties. When using the gel, the process of pain impulses passing through neurons slows down.

The anti-edematous effect of the drug is ensured by improving metabolic processes in the area of subcutaneous fat. The drug easily penetrates the skin.

Features of pharmacodynamics and pharmacokinetics

The maximum concentration of one of the main components of the gel for external use (dimethyl sulfoxide) in plasma is reached after six hours. As a rule, it lasts for up to twelve hours after applying the medication.

The heparin contained in the medication is practically not absorbed into the general bloodstream. Dexpanthenol present in the medicine is converted into pantothenic acid when applied locally.

The half-life of dimethyl sulfoxide varies from 11 to 14 hours. The active component of a pharmaceutical drug is excreted mainly by the kidneys: both in an unchanged state and in the form of a metabolite.

Mechanism of action

Dolobene is a combination medicine for local use. The characteristics of a medicine are determined by the ingredients that make up it.

The instructions for using dolobene gel indicate that dimethyl sulfoxide eliminates inflammatory processes, copes with swelling and pain. The anti-inflammatory characteristics of the substance are associated with a number of properties.

The most important of them is the fight against hydroxyl radicals. These elements are produced in significant quantities during the development of inflammation. They are the ones who lead to tissue destruction.

In addition, the element produces a local analgesic effect. This is achieved by reducing the rate of transmission of nociceptive impulses. The ability to cope with swelling is associated with the normalization of the subcutaneous metabolic reaction and the suppression of hydroxyl radicals in the area where the drug is applied. To a certain extent, the decongestant characteristics of the drug are associated with hygroscopic characteristics.

More than 50% of the product overcomes cell membranes. This ensures that the product penetrates sufficiently deep into the tissue.

Heparin increases anti-inflammatory properties and restores connective tissue due to the suppression of hyaluronidase. The drug produces an antithrombotic effect, increases the inhibitory effect of antithrombin on thrombin and prothrombin. The level of penetration of the substance through the intact dermis is determined by the dosage. This result is achieved at a volume of 300 IU/g.

Local use of dexpanthenol leads to the conversion of the substance into pantothenic acid, which belongs to the B vitamins. The effectiveness of the substance is comparable to the properties of pantothenic acid, which is an ingredient of coenzyme A.

This element is involved in anabolic and catabolic processes occurring in tissues. By normalizing epithelization and granulation, it is possible to accelerate the recovery of the affected areas of the dermis.

Contraindications

Contraindications and indications for use of the medicine are listed in detail in the instructions.
The use of the product should be avoided if you are hypersensitive to its components. Otherwise, the patient may experience unwanted complications such as itching and allergic skin reactions. The medication should not be applied to the body if a person has symptoms of bronchial asthma. With this pathology, breathing periodically worsens due to narrowing of the airways.
The use of medicinal gel can cause an exacerbation of the disease and the occurrence of bronchospasms. The use of the medicine should also be avoided if the patient has renal failure. The medication is excreted mainly through the kidneys, unchanged. When the excretory function of the kidneys deteriorates, the medicine gradually accumulates in the body, which can cause severe intoxication.

The medicine is not prescribed if the patient has severe liver disease. They are prohibited from treating open wounds, especially if there is heavy bleeding. When the skin is damaged, a larger amount of active substances of the gel enters the plasma than when the medicine is applied to intact skin. As a result, the risk of adverse consequences increases significantly.

In addition, when the heparin present in the product penetrates into a bleeding wound, the bleeding often increases: this substance prevents blood clotting.

Important! The gel should not be used if there are burns. The medication contains isopropanol, which is an alcohol. When applying the gel to burned skin, the patient's condition worsens significantly.

Indications

Anti-inflammatory ointment can be used for a large number of diseases and conditions. The heparin component of the drug makes it possible to use the drug also for vascular diseases.

Instructions for use of the product contain the following indications:

Injuries - domestic, sports, industrial, which are accompanied by bruises (bruise of the kneecap, foot) and other closed injuries of the musculoskeletal system.
Hematomas are accumulations of blood in subcutaneous tissues, including joint cavities.
Sprains and tears of muscles, ligaments, tendons.
Inflammation of the joint capsules and inversions of the synovial membrane - bursitis.
Fasciitis is inflammation of the tendon sheets (fascia).
Enthesopathies are a pathological process in the area of attachment of ligaments and muscles to bones.
Acute neuralgia of peripheral nerves.
Phlebitis is inflammation of the vein wall, thrombophlebitis is inflammation caused by blockage of a vein by a blood clot.
Varicose veins.
Trophic damage to the skin of the legs due to chronic venous insufficiency.

The use of ointment for arthritis and exacerbation of osteoarthritis is not contraindicated. However, the gel may not provide the necessary analgesic effect due to the low degree of penetration into the joint capsule.

Side effects

When using Dolobene, a variety of side effects may occur:

irritation. When you first apply the medicine, redness may occur on the affected area. The occurrence of this adverse reaction is due to the presence of isopropanol in the medication. In most cases, such an undesirable effect disappears on its own after several days;
allergy. When it appears, a person experiences a burning sensation and swelling in the treated area. In some cases, complications such as lethargy, fever, and excessive fatigue are observed. If signs of allergy occur, rinse the treated area thoroughly with clean water. If your health suddenly deteriorates, you should contact a medical facility;
the appearance of a specific odor from the oral cavity. This complication occurs quite rarely. The appearance of a strong odor from the mouth is caused by the penetration of a small amount of dimethyl sulfide into the lungs.

What does Dolobene ointment help with?

Today on the pharmaceutical market you can purchase any necessary medical drug with a fast-acting effect. As you know, each of us is not immune from bruises, sprains and other injuries, not only when playing sports, but also in everyday life.

When choosing the optimal treatment, it is better to give preference to a drug that will quickly relieve pain and promote healing of damaged tissue. One of these remedies is Dolobene gel; its healing properties deserve special attention.

Composition of Dolobene ointment

The main active substances contained in Dolobene penetrate the human body quite quickly. By interacting with each other, they quickly relieve pain and improve metabolic reactions under the skin.

Heparin improves local blood circulation, restores connective tissue, and accelerates the resorption of small blood clots. This substance has a dose-dependent antithrombotic property, inhibits the activity of hyaluronidase and regenerates connective tissue.

The local analgesic effect is achieved through the chemical substance dimethyl sulfoxide, which reduces pain impulses in nerve cells. Where the ointment was applied, hydroxyl radicals lose their activity, and metabolic reactions under the skin improve. An anti-edematous effect is achieved.

Dexpanthenol, entering the skin, is transformed into pantothenic acid, which is necessary for tissue processes, as a result of which injured skin areas are quickly regenerated. This substance has a dermatoprotective effect.

This medication is for external use only. It anesthetizes the damaged surface, relieves swelling and treats inflammation, and also copes well with various neuralgic processes.

Thus, Dolobene gel is excellent for those who have sprains, neuritis, or damaged muscle tissue. It helps well against bruises, bruises and swelling thanks to the active substances contained in this ointment.

The medicine should be stored for no more than 3 years, at a certain temperature - up to 25 degrees Celsius. The gel, packed in tubes weighing 50 grams, can be purchased at the pharmacy without a prescription.

What is the ointment for: indications for use

The ointment is used in the following cases:

for bruises, injuries with intact skin;
for diseases of the musculoskeletal system, including osteochondrosis, arthrosis, arthritis;
for hematomas and joint injuries;
with swelling of soft tissues;
with inflammation of the tendons (tendinitis) and tendon sheaths;
with thrombophlebitis;
when stretching muscles, tendons and ligaments;
for acute neuralgia;
with periarthritis of the glenohumeral joints.

Instructions for use Dolobene

To maximize the effect of the gel on the sore spot, it is necessary to properly prepare the skin. To do this, you need to thoroughly clean it of dirt, cosmetics, and other medications. It is strictly forbidden to apply the gel to damaged skin, bleeding wounds and mucous membranes.

A small amount of gel is rubbed into the skin of the painful area with light movements. You can apply a breathable bandage over the gel, but before using the dressing, you need to wait a little time for the alcohol contained in the preparation to evaporate from the surface of the skin. The gel should be applied two to four times a day. The duration of treatment is selected individually, taking into account the effectiveness of using Dolobene ointment and the severity of the disease.

Contraindications and side effects

This drug, like other medications, has a number of contraindications:

kidney and liver pathologies;
pathologies of the heart and blood vessels, stroke, angina pectoris and myocardial infarction;
presence of open wounds;
asthma;
lactation;
period of bearing a child;
individual intolerance.

The use of the gel is also contraindicated for children under five years of age. Before starting treatment with this drug, it is advisable to consult a doctor.

Undesirable reactions may occur during use:

unpleasant itching, redness, burning;
allergic relapses (rash, blisters, swelling);
sleep disturbance, nausea;
difficulty breathing, dizziness;
the appearance of a garlicky taste in the mouth;
replacement of taste perceptions.

Many side effects disappear on their own if you stop using the drug. In any case, if serious adverse reactions occur, you should immediately consult a doctor.

Use during pregnancy and lactation

It is not recommended to use the drug during pregnancy, since the safety of using the dimethyl sulfoxide component during pregnancy has not been confirmed by clinical trials.

But it has been experimentally confirmed that this component has a negative effect on the embryonic development of the fetus and is found in breast milk, so use is contraindicated during lactation.

How can you replace ointment: analogues

Heparin ointment is the cheapest substitute with a similar effect.
Fastum gel – medicinal active ingredient ketoprofen.
Voltaren emulgel is the main active ingredient of diclofenac.
Gel DIP Relief - medicinal substances ibuprofen and levomenthol.
Alezan cream contains many herbs in its composition.

Application diagram

The medicine is used during phonophoresis.
In this case, first a little medicine is applied to the affected area, then this area is exposed to ultrasonic waves. The procedure speeds up the process of penetration of the main components of the gel into tissues and helps improve blood circulation.

You can simply apply the gel to the affected area daily. The frequency of use of the medicine varies from two to four times a day. The medicine is allowed to be absorbed. After five minutes, a special sterile bandage made of sealed material is applied to the body.

Important! When using the drug, the photosensitivity of the skin may increase. During treatment you should avoid visiting the solarium. When using the medicinal gel, it is not recommended to sunbathe in direct sunlight.

Use of the product during pregnancy and breastfeeding

Dolobene should not be used during pregnancy. The drug can cause premature placental abruption and bleeding.

The medicine is not recommended for use during breastfeeding. Dolobene is not prescribed to children under five years of age.

special instructions

Before applying the gel, you must thoroughly cleanse the skin of cosmetics, other medications or any chemicals.
The gel should not be applied to the mucous membranes of the mouth, eyes, nose, damaged areas of skin and open wounds (due to severe sunburn, radiation, post-operative scars).
During drug therapy, the photosensitivity of the skin may increase. In this regard, you should limit your visits to the solarium and avoid intense sunbathing.
If skin reactions develop, therapy should be discontinued.
Due to the high absorption of dimethyl sulfoxide, it is not advisable to use Dolobene simultaneously with other gels and ointments.

Interaction with other medications and alcohol

During the treatment period, it is allowed to drink alcohol in moderation. This is due to the fact that the active components of the drug penetrate the systemic bloodstream in minimal concentrations.

Dolobene may enhance the effect of other medications intended for topical use. When the drug is used simultaneously with non-steroidal anti-inflammatory drugs made on the basis of sulindac, the likelihood of neuropathy increases.

Dolobene Gel: instructions for use

The drug Dolobene belongs to the group of direct-acting anticoagulants and has pronounced analgesic, anti-edematous, anti-inflammatory, regenerating and anti-thrombotic properties.

Release form and composition of the drug

The drug Dolobene is available in the form of a gel for external use in aluminum tubes of 50 g. The gel is a substance of uniform consistency, transparent with a slightly yellowish tint with a pronounced odor.

The main active ingredients of the gel are: sodium heparin, dexapanthenol, dimethyl sulfoxide. The drug also contains auxiliary components: essential oils of rosemary, citronella, mountain pine, polyacrylic acid, purified water.

Pharmacological properties of the drug

Dolobene gel is for external use only. The therapeutic effect of the drug is due to its constituent components.

Dimethyl sulfoxide relieves signs of inflammation, eliminates skin swelling, and reduces pain. This substance penetrates into the deep layers of the skin, acting directly on the pathological focus.

Heparin, which is part of the drug, has an anti-inflammatory effect, stimulates regeneration processes, and prevents the development of thrombosis.

Dexapanthenol penetrates into the deep layers of the skin and, under the influence of a series of chemical reactions, is converted into pantothenic acid (provitamin B). This substance stimulates skin regeneration processes, moisturizes and relieves signs of inflammation, and promotes rapid healing of damage.

Indications for use

Dolobene gel for external use is prescribed to patients for the treatment of the following pathologies:

Bruises;
Injuries, hematomas;
Swelling due to injury;
Inflammation of muscles, tendons and soft tissues;
Inflammation of the joints;
Acute neuralgia.

Contraindications

Dolobene gel can only be used as prescribed by a doctor. Before starting to use the drug, you should read the accompanying instructions in detail, as the medicine has the following contraindications:

Bronchial asthma;
Impaired blood clotting function;
Damage to the liver and kidneys;
Individual intolerance to the components of the drug;
Open wound surfaces;
Pregnancy and breastfeeding period;
Age in children under 5 years.

Method of administration and dosage of the drug

Dolobene can only be used on intact areas of the skin. The gel is applied to clean, dry skin in a thin layer and gently rubbed in with massage movements. It is recommended to apply the drug 2 to 4 times a day, depending on the severity of the clinical symptoms of the disease. If necessary, you can use a gauze bandage with a small amount of gel applied to it.

The duration of the course of treatment with the drug is determined by the doctor individually for each patient.

Use of the drug during pregnancy and lactation

The drug Dolobene is contraindicated for use among pregnant women due to the lack of reliable information regarding the effect of the active components of the gel on the intrauterine development of the fetus.

The use of the gel during lactation is contraindicated, since studies have shown that dimethyl sulfoxide penetrates into breast milk, and then into the child’s body with food. If drug therapy is necessary, the issue of stopping breastfeeding should be decided.

Side effects

If the recommendations specified in the instructions are followed, patients rarely develop negative reactions during therapy with Dolobene gel. In case of individual hypersensitivity to the constituent components of the drug, the patient develops the following side effects:

Local skin reactions - itching, burning, discomfort when applying the drug to the skin, urticaria;
In very rare cases, angioedema may develop;
The appearance of bad breath;
With prolonged uncontrolled use, systemic side effects may develop.

Drug overdose

When using the drug on large areas of skin for a long period of time, systemic signs of overdose may develop:

Depression of liver function;
Nausea, stomach pain;
Headache;
Weakness;
Increased breathing or decreased respiratory function;
Chills and general malaise.

If signs of drug overdose or accidental ingestion of Dolobene gel develop, the patient’s stomach is washed and symptomatic treatment is given if necessary.

Interaction of the drug with other drugs

When using Dolobene with indirect anticoagulants simultaneously, there may be a risk of bleeding.

When used simultaneously with the drug, other ointments or topical creams may complement each other's therapeutic effect.

Using gels or ointments from the group of non-steroidal anti-inflammatory drugs together with Dolobene increases the risk of developing neuropathy.

special instructions

The drug Dolobene can only be applied to a dry, previously cleansed skin surface. Do not use the product on mucous membranes or wound surfaces. If the drug accidentally gets into your eyes, rinse them with plenty of clean water and immediately consult an ophthalmologist.

The gel must not be applied to postoperative scars, burn areas, or ulcerative surfaces.

Since the patient’s photosensitivity increases during drug therapy, it is not recommended to visit solariums or stay in open sunlight for a long time at this time.

For children under 12 years of age, the daily dose of the drug and the duration of the course of therapy are determined by the doctor depending on the individual characteristics of the body.

Analogs of Dolobene gel

Analogs of the drug Dolobene are the following:

Hepatrombin C;
Heparin ointment.

Before replacing a prescribed drug with its analogue, the patient should consult a doctor.

Conditions of release and storage

Dolobene is sold in pharmacies without a prescription. The optimal storage temperature for the drug is 25 degrees. Do not allow the medicine to freeze, do not use after the expiration date, keep away from children.

Price

The average cost of Dolobene in Moscow pharmacies is 315 rubles.

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Drug analogues

There are substitutes for Dolobene.
For burns, it is better to use Panthenol, and for minor injuries (bruises) gul Traumeel or Badyaga. If you have an allergic reaction to the gel, you can use other medications with similar therapeutic properties. If there is an injury (bruise), Dolobene can be replaced with the following medications:

essentially any ointment/gel made on the basis of heparin, for example the popular Lyoton gel;
Traumeel S. This combination medicine has a pronounced antimicrobial effect. Traumeel S is excellent for treating soft tissue damage and injuries.

What to prefer: Dolobene, Fastum gel or Diclofenac?

There is no doubt about whether to choose Dolobene or Diclofenac. After all, the drugs differ significantly in their mechanism of action. Diclofenac has a pronounced anti-inflammatory effect, reduces the inflammatory process in the affected area, helps relieve swelling, and relieves pain.

Unlike Dolobene, Diclofenac does not accelerate the process of skin restoration in the affected area. It does not have a noticeable effect on the metabolism in the affected tissues.

The answer to the question, which is better, Dolobene or Fastum gel, is also obvious. The drug Fastum Gel also contains components that have a pronounced anti-inflammatory effect. According to the mechanism of action, the drug is not much different from the well-known Diclofenac, essentially being its analogue.

What does Dolobena ointment help with - composition and effect

Bruises, injuries, sprains, strains occur in the life of every person, fortunately, in the modern world it is not a problem to purchase a drug that will relieve pain and heaviness in the legs; one of the effective medicines is Dolobene ointment.

Composition and release form

Dolobene gel (ointment) for external use is available in 50 ml tubes, in a cardboard box. The product has a yellowish tint and a thick consistency.

Pharmacological group - an anticoagulant agent for local use, relieves the feeling of heaviness in the muscles, helps to resolve hematomas, and has an analgesic effect. Used in a course for external application.

Composition of ingredients of Dolobene ointment:

active ingredients: Dexpanthenol, Sodium Heparin, Dimethyl sulfoxide;
mountain pine oil;
rosemary oil;
isopropanol;
lemongrass oil;
polyacrylic acid;
purified water;
trometamol

The ointment is effective for varicose veins and spider veins, since the active substance Heparin enhances the activity of antithrombin III. It is recommended for prophylactic use when using oral contraceptives, to strengthen the walls of blood vessels and prevent varicose veins.

pharmachologic effect

The main direction of action of the ointment is anti-edematous and anti-inflammatory.

The action of the combined drug Dolobene occurs due to the active substances included in the composition:

heparin - helps accelerate metabolism and tissue regeneration, helps resolve bruises and hematomas. Has an anti-inflammatory effect;
dimethyl sulfoxide - effectively relieves swelling and a feeling of heaviness, analgesizes, reduces the inflammatory process. Penetrates through the skin and biological membranes, which allows the delivery of active substances to the deep layers of tissue;
dexpanthenol – when rubbed into the skin, it is converted into a B vitamin, which regenerates skin cells.

The components of the ointment are eliminated from the body within 14 hours after application.

Indications for use

Dolobene ointment has proven itself in many cases; the main indications for the use of this drug are:

hematomas, bruises, swelling that occurred from traumatic causes - external application of Dolobene quickly eliminates inflammation and reduces swelling in a matter of days. In this case, the ointment helps strengthen blood vessels;
muscle inflammation;
inflammatory processes in soft tissues, tendons, tendonitis;
traumatic disorders in the joints;
sprain of ligaments and tendons - the product quickly eliminates the symptoms of these injuries in the form of swelling and pain, Dolobene components accelerate metabolism, due to which the ligaments are restored faster;
bursitis;
thrombophlebitis - a course of use of Dolobene can restore damaged skin, strengthen the walls of blood vessels and veins, the medicine will not allow blood clots to increase in size;
arthrosis - for this disease, the use of ointment accelerates metabolism and blood microcirculation in the diseased area, slows down the breakdown of cartilage tissue, and prevents the disease from progressing;
arthritis – Dolobene removes inflammatory processes in joints, relieves pain;
myositis - applying Dolobena gel for a course of 5 days will completely relieve the symptoms of the disease and the inflammatory process;
varicose veins – used for varicose veins of the legs, helps prevent the progression of the disease, removes the feeling of heaviness and cramps in the legs;
neuralgia of any etymology – Dolobene prevents relapse of neuralgia.

Instructions for use

Dolobena ointment should be applied to the affected area of skin in a thin layer 2 to 4 times a day. Dolobene should be rubbed in carefully, in a circular motion until completely absorbed. If the area of skin is severely affected, there are open wounds on it, then you should not rub the product, you need to apply and leave the drug, it will be absorbed into the tissue over time.

Important! Before applying the drug to the skin, the painful area must be washed and cleared of any blockages; there should be no residues of other drugs on it, as a conflict of drug compatibility may occur. Dolobene gel can be effectively used in the form of compresses, instructions for use:

rinse the skin and dry it from drops of water;
apply a thin layer of gel to the affected area;
wait until the ointment is absorbed;
Place gauze folded several times on top.

In this case, you cannot make compresses that are classic from the point of view of ordinary people, in which the ointment is applied to a piece of fabric, applied to the sore spot, and covered with polyethylene or something warm on top. This technique will steal most of the active substances from the wounded tissues; they will be absorbed into the fabric bandage. To achieve the effect, you will have to use a larger amount of Dolobene, which is not economical, given the considerable price of the ointment.

The duration of the course can be 5-14 days; usually, the duration of use of the drug is determined by the doctor, based on the degree and nature of the damage. In case of urgent need and severity of the disease, the gel can be applied for more than two weeks.

This ointment is used during ultrasound procedures, as a contact gel, which increases the permeability of the device’s waves. It can also be used during iontophoresis.

Contraindications and side effects

Contraindications to the use of Dolobene ointment:

allergic skin reactions, individual intolerance to the components of the composition;
pathologies of the cardiovascular system;
bronchial asthma (the drug cannot be used, even if the patient has only a history of this disease);
severe liver and kidney diseases, dysfunction of these organs;
open wound;
not for children under 5 years of age;
pregnancy;
lactation and breastfeeding (components of the ointment may pass into breast milk).

In the instructions provided with the tube of ointment, you can find lines that state that using the ointment to treat children under 5 years of age is prohibited. But none of the components included in the composition have such age-related contraindications individually, and some of them can be used in cases with infants.

Important! There is an opinion among experts that it is precisely this combination of active components, as in Doloben, that can provoke metabolic disorders in young children.

Possible side effects:

allergic reactions (expressed in the appearance of redness, itching, irritation of the skin);
Quincke's edema (rare);
changes in the perception of taste buds;
nausea and vomiting;
intestinal disorders;
lack of air for a full breath;
headache;
the smell and taste of garlic in the mouth.

Important! Do not apply the ointment to mucous membranes of the skin (nose, eyes, mouth) or to open wounds, postoperative sutures, or at the site of sores.

During the entire period of use of the ointment, it is strictly not recommended to be in direct sunlight or visit a solarium, since the absorption of the Dolobene drug increases the photosensitivity of the skin.

If the skin gives a negative reaction to the application of the drug, then the course of treatment must be stopped and an analogue must be selected. You should not combine this ointment with other pain-relieving gels, especially those from the NSAID group containing sulindac; such a combination can cause toxic reactions.

Price

Ointment in a tube 50g. – 350-450 rubles.

Analogs

The main structural analogue of Dolobene is Hepatrombin C; this drug contains the same active substances as in Dolobene gel.

Other analogues are anticoagulants:

Heparin ointment is a Russian analogue of Dolobene ointment, the price of the drug is about 90 rubles in pharmacies, it is used for thrombophlebitis, injuries, varicose veins;
Lyoton - price higher than Dolobene, effectively relieves swelling, pain and swelling in the legs;
Venolife is an effective Russian drug with a low price, effective against swelling, pain in muscles and joints, tissue injuries, ulcers;
Troxevasin – lower price: for 50g. – 240 rubles, used for hematomas, bruises, thromboses;
Venabos – used for leg cramps, varicose veins, injuries and swelling;
Traumeel is a homeopathic remedy that can be used for inflammation and traumatic disorders of the musculoskeletal system. Price about 500 rub.;
Comfrey ointment is a cheap option for an anticoagulant drug that can restore damaged joints, relieve swelling, and accelerate the exchange of calcium and phosphorus in bone tissue.

Reviews

“I used Dolobene ointment while taking OK, there was a constant feeling of heaviness in my legs, all the muscles ached and twisted, after several doses of the drug there was relief. Now I use the ointment periodically to prevent varicose veins and the appearance of spider veins, my legs are fine and look healthy.”

“The product helps well with joint pain. In winter, I fell on my left knee, after which I could not step on my leg. The doctor prescribed compresses with the drug Dolobene. Compresses relieved tension and pain well. In addition to compresses, I smeared a thin layer of the drug on my knee at night, it really helps, I always keep it in my first aid kit just in case.”

“Several years ago, my son broke his arm, after removing the cast we started using this ointment, applying a thin layer superficially to the damaged arm three times a day. The swelling around the bone began to decrease immediately, and the son stopped complaining of unbearable pain. The drug, of course, is not cheap, but it is effective, and in some cases there is no room for savings.”

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Reviews

Reviews from doctors about Doloben are generally positive. Thanks to the combined composition, the medicine quickly eliminates inflammation and improves blood circulation.

Many people who use the medication to treat sprains and bruises speak favorably of Doloben. The gel is well absorbed and eliminates painful sensations without leaving greasy stains on the laundry.

Some note that the medicine is not effective enough in the presence of pain after a fracture or extensive damage to soft tissues. Below are a few reviews as an example. You can always leave your feedback in the comments at the end of the article.

Ivan, 32 years old: “I am actively involved in sports.
I recently sprained my ankle. The pain was very strong. But Dolobene gel helped to cope with the problem. The pain disappeared, the swelling of the joint noticeably decreased. Dolobene gel is a very effective and high-quality product.” Pavel Egorovich, 56 years old: “The medicinal gel helps a lot with joint pain.
I actively use this product. I apply it to sore joints twice a day. I tried to be treated with cheaper ointments, but, unfortunately, I did not notice any special effect after using them.” Larisa Yuryevna, 65 years old: “I used the gel for the first time after I had a bad fall in winter and broke my arm. I applied the medicine three times a day. I noticed a positive result quickly. The swelling went away, the hand stopped aching.

Not long ago I was diagnosed with bursitis. Dolobene came to my rescue again. The product is perfectly absorbed and does not cause an allergic reaction. The only drawback of the drug is its relatively high cost. For me, a pensioner, it is a little expensive. But you don’t have to skimp on your health.”

conclusions

Let's summarize:

Dolobene – gel for topical use. Prescribed for bruises, hematomas, sprains, inflammatory diseases of periarticular tissues, after injury.
Dolobene has analgesic, anti-inflammatory and regenerative effects. It effectively relieves pain and swelling of tissues and accelerates their healing.
Dolobene gel is used in children over 5 years of age and adults. Not used during pregnancy and lactation.
Dolobene is well tolerated. Sometimes local reactions occur in the form of itching and burning of the skin. It is possible to develop an allergy to the drug.